𝕏

Task 54994940

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_149_0
Workunit 26113341
Created 27 Jun 2024, 17:49:29 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 1 Jul 2024, 8:08:22 UTC
Received 29 Jun 2024, 1:40:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 2 hours 59 min 14 sec
CPU time 2 hours 23 min 22 sec
Validate state Valid
Credit 55.67
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.29 MB
Peak swap size 5.33 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_149.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_149_0_r1446798709_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_149_0_r1446798709_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 92.931623
     * GNaL_b in INaL: 0.006890
     * Gto_b in Ito: 0.073803
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030145
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.153677
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 69.323227
     * GKb_b in IKb: 0.003889
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023161
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12537295, states[0] = 16.798991, states[40]= 0.005488
Saving checkpoint... 
Iteration: 21698027, states[0] = -94.661947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30342683, states[0] = -94.826696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39169878, states[0] = -91.169639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46976891, states[0] = -94.852547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55468076, states[0] = -94.845341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63864831, states[0] = -94.810289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70220656, states[0] = -94.659002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75032986, states[0] = 19.050875, states[40]= 0.005769
Saving checkpoint... 
Iteration: 82367843, states[0] = -94.805318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96652328, states[0] = -64.773001, states[40]= 0.000002
Saving checkpoint... 
Iteration: 111209654, states[0] = -94.628497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123888385, states[0] = -94.807677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136909333, states[0] = -94.813960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151022077, states[0] = 22.252006, states[40]= 0.008192
Saving checkpoint... 
Iteration: 162783787, states[0] = -94.738293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170449386, states[0] = -94.823079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180339928, states[0] = -94.782583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188665064, states[0] = -81.920275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196102339, states[0] = -16.874396, states[40]= 0.001262
Saving checkpoint... 
Iteration: 208389196, states[0] = -94.805605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214292298, states[0] = -94.746102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223090642, states[0] = -7.108540, states[40]= 0.002959
Saving checkpoint... 
Iteration: 232620168, states[0] = -32.496542, states[40]= 0.000402
Saving checkpoint... 
Iteration: 240842073, states[0] = -94.783403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249249337, states[0] = -94.694637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257909485, states[0] = -94.812250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266753944, states[0] = -94.701220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274975881, states[0] = -94.827314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282560701, states[0] = 8.870522, states[40]= 0.004956
Saving checkpoint... 
Iteration: 291209751, states[0] = -94.624888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299139285, states[0] = -50.498384, states[40]= 0.000029
Saving checkpoint... 
Iteration: 307307773, states[0] = -94.759543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315602620, states[0] = -17.107057, states[40]= 0.001238
Saving checkpoint... 
Iteration: 324479891, states[0] = -94.827899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333089830, states[0] = -6.500023, states[40]= 0.003091
Saving checkpoint... 
Iteration: 341115073, states[0] = -28.010164, states[40]= 0.000636
Saving checkpoint... 
Iteration: 348697630, states[0] = -94.597579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356277189, states[0] = -94.730254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365063274, states[0] = 7.800673, states[40]= 0.004918
Saving checkpoint... 
Iteration: 372759309, states[0] = -94.708450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381244449, states[0] = -94.687125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389747132, states[0] = -94.691201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398258648, states[0] = -94.707549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407075775, states[0] = 2.058125, states[40]= 0.004530
Saving checkpoint... 
Iteration: 414994666, states[0] = -94.829993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423712786, states[0] = -94.630901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430196140, states[0] = -94.593121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440319008, states[0] = -94.768120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450493388, states[0] = -94.829794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460827130, states[0] = -94.773805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471255714, states[0] = -94.703507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481819862, states[0] = -94.768713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493139781, states[0] = -51.000246, states[40]= 0.000027
Saving checkpoint... 
Iteration: 505227345, states[0] = -94.658495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515357314, states[0] = -94.791383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525602377, states[0] = -16.892990, states[40]= 0.001260
Saving checkpoint... 
Iteration: 535519312, states[0] = 22.875620, states[40]= 0.010149
Saving checkpoint... 
Iteration: 545479685, states[0] = -94.827710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556032945, states[0] = 19.182636, states[40]= 0.005779
Saving checkpoint... 
Iteration: 566406504, states[0] = -94.811067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576119599, states[0] = -31.988014, states[40]= 0.000427
Saving checkpoint... 
Iteration: 585546311, states[0] = 14.474475, states[40]= 0.005134
Saving checkpoint... 
Iteration: 595612842, states[0] = -26.058589, states[40]= 0.000735
Saving checkpoint... 
Iteration: 606069169, states[0] = 5.225392, states[40]= 0.004788
Saving checkpoint... 
Iteration: 616320125, states[0] = -94.768812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626636862, states[0] = -48.060999, states[40]= 0.000043
Saving checkpoint... 
Iteration: 637203342, states[0] = -94.611157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646947840, states[0] = -94.821785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656338351, states[0] = -94.780833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665499098, states[0] = -94.830413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674545156, states[0] = 14.903780, states[40]= 0.005159
Saving checkpoint... 
Iteration: 683749305, states[0] = -94.694229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692559811, states[0] = 9.234970, states[40]= 0.004968
Saving checkpoint... 
Iteration: 701642433, states[0] = -53.711416, states[40]= 0.000017
Saving checkpoint... 
Iteration: 710812096, states[0] = -94.762712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720767548, states[0] = -94.718743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731453077, states[0] = -94.822817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742121939, states[0] = -34.061604, states[40]= 0.000332
Saving checkpoint... 
Iteration: 751285327, states[0] = -94.738667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760627696, states[0] = -39.262546, states[40]= 0.000163
Saving checkpoint... 
Iteration: 769895807, states[0] = -94.807388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779211340, states[0] = -94.627757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787154330, states[0] = -66.673175, states[40]= 0.000002
Saving checkpoint... 
Iteration: 795545890, states[0] = 14.631358, states[40]= 0.005143
Saving checkpoint... 
Iteration: 803045718, states[0] = 14.695318, states[40]= 0.005146
Saving checkpoint... 
Iteration: 810398681, states[0] = -94.808347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819712533, states[0] = -94.630125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827170564, states[0] = -89.653136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833634505, states[0] = -45.730032, states[40]= 0.000062
Saving checkpoint... 
Iteration: 842404608, states[0] = -94.810278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851054568, states[0] = 11.324516, states[40]= 0.005025
Saving checkpoint... 
Iteration: 858119360, states[0] = -31.776866, states[40]= 0.000438
Saving checkpoint... 
Iteration: 865374565, states[0] = -94.799133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872751803, states[0] = -94.697729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880350810, states[0] = -94.787764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888395323, states[0] = -94.807139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896920034, states[0] = -94.814840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905401316, states[0] = -94.809164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914121033, states[0] = -33.256758, states[40]= 0.000367
Saving checkpoint... 
Iteration: 921595123, states[0] = -10.649242, states[40]= 0.002208
Saving checkpoint... 
Iteration: 929497729, states[0] = -94.830055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937570571, states[0] = 4.582077, states[40]= 0.004746
Saving checkpoint... 
Iteration: 946409879, states[0] = -94.811855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954535676, states[0] = 18.278756, states[40]= 0.005559
Saving checkpoint... 
Iteration: 962950087, states[0] = -94.822045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971392188, states[0] = -94.805970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979673195, states[0] = -91.931950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987685861, states[0] = -94.501046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996259170, states[0] = -94.707839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005020333, states[0] = 22.657912, states[40]= 0.009276
Saving checkpoint... 
Iteration: 1012416199, states[0] = -94.813680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020248263, states[0] = -94.692460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028536082, states[0] = 18.141147, states[40]= 0.005531
Saving checkpoint... 
Iteration: 1036602629, states[0] = -17.114141, states[40]= 0.001238
Saving checkpoint... 
Iteration: 1041921975, states[0] = -94.815275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055226427, states[0] = -94.656464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068762702, states[0] = -94.712418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086693468, states[0] = -94.582755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107367805, states[0] = -94.795995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128904386, states[0] = -94.810013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151843933, states[0] = -94.783777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174640051, states[0] = -51.274070, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1203056628, states[0] = 10.513767, states[40]= 0.005004
Saving checkpoint... 
Iteration: 1229448087, states[0] = -94.821444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256518328, states[0] = 23.076371, states[40]= 0.011230
Saving checkpoint... 
Iteration: 1282476124, states[0] = -94.826642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313203244, states[0] = -94.610480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343308846, states[0] = -94.759699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373700562, states[0] = -94.604337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403195195, states[0] = -94.589315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433477082, states[0] = -94.826695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464395225, states[0] = -94.806714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495972089, states[0] = -94.825828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530288217, states[0] = -95.088534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564646715, states[0] = -90.029517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605100468, states[0] = -32.346368, states[40]= 0.000398
Saving checkpoint... 
Iteration: 1641999774, states[0] = -31.731357, states[40]= 0.000426
Saving checkpoint... 
Iteration: 1690970965, states[0] = -94.923439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747405789, states[0] = -95.008890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803379963, states[0] = -94.858214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845958839, states[0] = -94.842014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863032464, states[0] = 19.212669, states[40]= 0.005818
Saving checkpoint... 
Iteration: 1879803740, states[0] = -94.762039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890911032, states[0] = -94.816513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897546751, states[0] = 14.252933, states[40]= 0.005127
Saving checkpoint... 
Iteration: 1906330120, states[0] = -94.777943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915132150, states[0] = -43.593178, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1921862780, states[0] = -94.795062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930766619, states[0] = -94.718285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939998484, states[0] = -94.830592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1949651972, states[0] = -63.989318, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1960329940, states[0] = -94.775248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970909010, states[0] = -94.811311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983807550, states[0] = -94.758478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993721067, states[0] = -94.646099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004762946, states[0] = -94.712212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016146920, states[0] = -58.401112, states[40]= 0.000008
Saving checkpoint... 
Iteration: 2021744464, states[0] = -94.686076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2031549623, states[0] = 13.226926, states[40]= 0.005080
Saving checkpoint... 
Iteration: 2039724805, states[0] = -94.652838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048671604, states[0] = -90.686052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058585708, states[0] = -3.640097, states[40]= 0.003683
Saving checkpoint... 
Iteration: 2064001035, states[0] = 46.211523, states[40]= 0.035504
Saving checkpoint... 
Iteration: 2070980230, states[0] = -94.826727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078061515, states[0] = 8.535419, states[40]= 0.004945
Saving checkpoint... 
Iteration: 2089911406, states[0] = -94.811495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099451358, states[0] = -94.821489, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.705384
 - CaMKt in component CaMK (millimolar): 0.007255
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.642125
 - nass in component intracellular_ions (millimolar): 6.642184
 - ki in component intracellular_ions (millimolar): 145.331694
 - kss in component intracellular_ions (millimolar): 145.331676
 - cansr in component intracellular_ions (millimolar): 1.328114
 - cajsr in component intracellular_ions (millimolar): 1.289311
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003691
 - hf in component INa (dimensionless): 0.876550
 - hs in component INa (dimensionless): 0.876545
 - j in component INa (dimensionless): 0.876511
 - hsp in component INa (dimensionless): 0.719356
 - jp in component INa (dimensionless): 0.876489
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.702424
 - hLp in component INaL (dimensionless): 0.439561
 - a in component Ito (dimensionless): 0.000632
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.611336
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.683788
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.928556
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999861
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001673
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.347375
 - xs1 in component IKs (dimensionless): 0.253441
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997388
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:40:16 (5048): called boinc_finish(0)

</stderr_txt>
]]>


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