𝕏

Task 54994910

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_4000-conf_549_0
Workunit 26113326
Created 27 Jun 2024, 17:49:29 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 30 Jun 2024, 22:32:22 UTC
Received 29 Jun 2024, 3:53:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 2 hours 37 min 50 sec
CPU time 2 hours 26 min 37 sec
Validate state Valid
Credit 39.55
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.27 MB
Peak swap size 5.29 MB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_4000-conf_549.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_4000-conf_549_0_r788058370_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pieske_4000-conf_549_0_r788058370_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.190051
     * GNaL_b in INaL: 0.004779
     * Gto_b in Ito: 0.091171
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033780
     * GKs_b in IKs: 0.001862
     * GK1_b in IK1: 0.147193
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 71.878210
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018642
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10636921, states[0] = -86.743383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19398532, states[0] = -86.655552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25448552, states[0] = -86.610833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33216122, states[0] = -86.570467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43583308, states[0] = -86.521471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52281496, states[0] = -86.342891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63026107, states[0] = -86.479914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71560066, states[0] = -86.455064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79268545, states[0] = -86.449139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87654015, states[0] = -86.433531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98190981, states[0] = -83.983956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107974041, states[0] = -86.414283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118887470, states[0] = -86.426471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127583762, states[0] = -86.409031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131480610, states[0] = -86.409173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142412356, states[0] = -86.372819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152154258, states[0] = -47.881000, states[40]= 0.000037
Saving checkpoint... 
Iteration: 164920475, states[0] = -86.413261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172010744, states[0] = 20.859150, states[40]= 0.036637
Saving checkpoint... 
Iteration: 183524146, states[0] = -86.398471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192464823, states[0] = -86.385102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205518266, states[0] = -86.396892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219106962, states[0] = -86.404341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229778447, states[0] = -86.392499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242966600, states[0] = -86.406929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254779096, states[0] = -86.409796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259159215, states[0] = -86.402031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264979145, states[0] = -86.406229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277041034, states[0] = -86.404603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284723528, states[0] = -86.409300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296400316, states[0] = -86.356600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305368113, states[0] = -86.397194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309218605, states[0] = -86.400207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317052419, states[0] = -86.404046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325903014, states[0] = -86.390025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338537805, states[0] = -86.397442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351704011, states[0] = -86.392000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364098552, states[0] = -2.172781, states[40]= 0.003377
Saving checkpoint... 
Iteration: 374068562, states[0] = 10.441512, states[40]= 0.004136
Saving checkpoint... 
Iteration: 379045114, states[0] = -86.404074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385996331, states[0] = -86.389120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395944006, states[0] = -86.389537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405761378, states[0] = -86.391283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414413087, states[0] = -86.362625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425109269, states[0] = -86.402495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436560729, states[0] = -86.400359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443018447, states[0] = -86.404670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449323933, states[0] = -86.397780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457766704, states[0] = -86.391198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468666659, states[0] = -86.407721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474301498, states[0] = -86.271932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483159941, states[0] = -86.401282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496141709, states[0] = -36.617175, states[40]= 0.000215
Saving checkpoint... 
Iteration: 508206263, states[0] = -86.016803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518608828, states[0] = -86.404788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527233938, states[0] = -86.399613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534021520, states[0] = 21.051360, states[40]= 0.006343
Saving checkpoint... 
Iteration: 544459644, states[0] = -86.380272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548749410, states[0] = -86.409024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558868817, states[0] = -86.407900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569965433, states[0] = -86.389292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579656654, states[0] = -86.392447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588923515, states[0] = -86.406816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598274382, states[0] = -86.232244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605864781, states[0] = -86.390169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615272962, states[0] = -86.398765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625653073, states[0] = -86.392481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638027500, states[0] = 20.466688, states[40]= 0.004841
Saving checkpoint... 
Iteration: 646770643, states[0] = -86.408991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655852392, states[0] = -86.390275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664828779, states[0] = -86.408496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673379987, states[0] = -86.396660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683589273, states[0] = -86.393312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691581897, states[0] = -86.393412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699624742, states[0] = -86.392830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711754323, states[0] = -86.391268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721838925, states[0] = -86.390390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728123085, states[0] = -20.750554, states[40]= 0.000873
Saving checkpoint... 
Iteration: 738466855, states[0] = -86.382358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744934264, states[0] = -86.406548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755383269, states[0] = -86.396581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762421380, states[0] = -86.366251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773025728, states[0] = -86.404412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781391129, states[0] = -86.396433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791750088, states[0] = -86.391297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801928833, states[0] = -86.389547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812467925, states[0] = -86.382646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822785734, states[0] = -86.408883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833277128, states[0] = -86.398629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844072416, states[0] = 9.158471, states[40]= 0.004128
Saving checkpoint... 
Iteration: 854811054, states[0] = -86.408663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865512181, states[0] = -86.394394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876337648, states[0] = -86.311840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886641343, states[0] = -86.406607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897712267, states[0] = -86.391702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908070803, states[0] = 9.704728, states[40]= 0.004133
Saving checkpoint... 
Iteration: 918719620, states[0] = -86.408747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929721045, states[0] = -86.391593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940103497, states[0] = -5.196308, states[40]= 0.002889
Saving checkpoint... 
Iteration: 950502133, states[0] = -86.390933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960993714, states[0] = -86.405135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971449072, states[0] = -86.395383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982283218, states[0] = -86.246074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992991761, states[0] = -86.405174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003819340, states[0] = -86.390520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014762527, states[0] = -86.408925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025312134, states[0] = -86.397875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036161196, states[0] = -53.741035, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1046865037, states[0] = -86.407856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057623995, states[0] = -86.392759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068641835, states[0] = -86.406590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079239643, states[0] = -86.399364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090395649, states[0] = -86.353649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101403945, states[0] = -86.396131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112016857, states[0] = 21.166502, states[40]= 0.010406
Saving checkpoint... 
Iteration: 1123067222, states[0] = -86.403332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133739392, states[0] = -86.391339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144197777, states[0] = -85.417404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154959137, states[0] = -86.405898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165229574, states[0] = -86.399563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175519704, states[0] = -86.394209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185651320, states[0] = -86.392377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196193084, states[0] = -84.199434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206501354, states[0] = -86.390713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216994995, states[0] = -86.405047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227312057, states[0] = -86.397831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238031905, states[0] = 19.788926, states[40]= 0.004408
Saving checkpoint... 
Iteration: 1248540623, states[0] = -86.397545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258214974, states[0] = -86.113306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268237059, states[0] = -86.164393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278174563, states[0] = -66.666515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287468036, states[0] = -86.394998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296775646, states[0] = -86.408827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307264004, states[0] = -86.398795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317840698, states[0] = -86.390238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328529968, states[0] = -86.395915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338994763, states[0] = -86.405025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349202246, states[0] = -86.400123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359746023, states[0] = -86.391214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370539459, states[0] = -86.397349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380986400, states[0] = -86.405213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402613843, states[0] = -86.404932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422944666, states[0] = -86.406165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439862028, states[0] = -86.390006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450085252, states[0] = 4.286222, states[40]= 0.003980
Saving checkpoint... 
Iteration: 1460032157, states[0] = 19.745013, states[40]= 0.004390
Saving checkpoint... 
Iteration: 1468283109, states[0] = -86.245797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477577807, states[0] = -86.393292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485364880, states[0] = -86.396756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493082618, states[0] = -86.402878, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.264773
 - CaMKt in component CaMK (millimolar): 0.000917
 - cass in component intracellular_ions (millimolar): 0.000070
 - nai in component intracellular_ions (millimolar): 5.954403
 - nass in component intracellular_ions (millimolar): 5.954450
 - ki in component intracellular_ions (millimolar): 146.037912
 - kss in component intracellular_ions (millimolar): 146.037902
 - cansr in component intracellular_ions (millimolar): 1.265678
 - cajsr in component intracellular_ions (millimolar): 1.265783
 - cai in component intracellular_ions (millimolar): 0.000072
 - m in component INa (dimensionless): 0.008637
 - hf in component INa (dimensionless): 0.639513
 - hs in component INa (dimensionless): 0.639514
 - j in component INa (dimensionless): 0.639517
 - hsp in component INa (dimensionless): 0.390438
 - jp in component INa (dimensionless): 0.639519
 - mL in component INaL (dimensionless): 0.000256
 - hL in component INaL (dimensionless): 0.459348
 - hLp in component INaL (dimensionless): 0.270482
 - a in component Ito (dimensionless): 0.001116
 - iF in component Ito (dimensionless): 0.999409
 - iS in component Ito (dimensionless): 0.985420
 - ap in component Ito (dimensionless): 0.000569
 - iFp in component Ito (dimensionless): 0.999409
 - iSp in component Ito (dimensionless): 0.991535
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997568
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001329
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.019631
 - xs1 in component IKs (dimensionless): 0.036821
 - xs2 in component IKs (dimensionless): 0.000231
 - xk1 in component IK1 (dimensionless): 0.997157
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:53:10 (25028): called boinc_finish(0)

</stderr_txt>
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