𝕏

Task 54994858

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_6000-conf_949_0
Workunit 26113300
Created 27 Jun 2024, 17:49:29 UTC
Sent 27 Jun 2024, 22:32:21 UTC
Report deadline 30 Jun 2024, 22:32:21 UTC
Received 28 Jun 2024, 5:14:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 3 hours 20 min 9 sec
CPU time 3 hours 0 min 53 sec
Validate state Valid
Credit 43.89
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.26 MB
Peak swap size 5.28 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_6000-conf_949.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_6000-conf_949_0_r1743435055_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_MID_6000-conf_949_0_r1743435055_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 108.441185
     * GNaL_b in INaL: 0.005407
     * Gto_b in Ito: 0.086050
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032560
     * GKs_b in IKs: 0.001986
     * GK1_b in IK1: 0.170501
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 69.007362
     * GKb_b in IKb: 0.003929
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024842
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11859167, states[0] = -94.179608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34115372, states[0] = -94.194545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51231746, states[0] = -32.499342, states[40]= 0.004574
Saving checkpoint... 
Iteration: 59069736, states[0] = -94.190271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66126519, states[0] = 7.142869, states[40]= 0.000067
Saving checkpoint... 
Iteration: 74680319, states[0] = -94.195123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82383797, states[0] = -94.214213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90539163, states[0] = -94.182657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98284908, states[0] = -94.206482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107146476, states[0] = -94.209983, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113511970, states[0] = -94.208982, states[40]= 0.000001
Saving checkpoint... 
Iteration: 121732771, states[0] = -94.217999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 130138484, states[0] = -94.233139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137757665, states[0] = -94.211879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146619566, states[0] = -94.213221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155230812, states[0] = -94.216068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 163194441, states[0] = -94.234446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170920395, states[0] = -94.214009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179291902, states[0] = -94.216852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188744907, states[0] = -94.215028, states[40]= 0.000001
Saving checkpoint... 
Iteration: 197824347, states[0] = -94.215036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205296229, states[0] = -94.232903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212780552, states[0] = -94.215367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 221559764, states[0] = -94.216185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229853733, states[0] = -94.222046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237787538, states[0] = -94.243137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244719965, states[0] = -94.224069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 253361930, states[0] = -94.231447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 261341948, states[0] = -93.906048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270878145, states[0] = -94.243770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277469671, states[0] = -94.228826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285216651, states[0] = -33.597468, states[40]= 0.003359
Saving checkpoint... 
Iteration: 293196881, states[0] = -94.218340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301017915, states[0] = -94.240939, states[40]= 0.000001
Saving checkpoint... 
Iteration: 308061463, states[0] = -94.219481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 315967660, states[0] = -94.242109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324786989, states[0] = -94.242852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333183435, states[0] = -20.629141, states[40]= 0.002275
Saving checkpoint... 
Iteration: 341147908, states[0] = -94.218485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348803309, states[0] = -94.243075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356318454, states[0] = -94.217094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 365810123, states[0] = -94.214940, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373789249, states[0] = -94.222410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 381496053, states[0] = -94.171103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388403869, states[0] = -94.229724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 396262977, states[0] = -70.968859, states[40]= 0.000019
Saving checkpoint... 
Iteration: 404378493, states[0] = -94.216403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413098329, states[0] = -94.218465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421283487, states[0] = -94.232602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429687042, states[0] = -94.235783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438783330, states[0] = -94.242010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446939223, states[0] = -94.214148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455373955, states[0] = -94.216086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463087170, states[0] = -94.237964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471391934, states[0] = -94.038098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478839590, states[0] = -94.220987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486876350, states[0] = -94.242465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493927413, states[0] = -94.219749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502790255, states[0] = -94.221526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 511362947, states[0] = -94.229904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 520417394, states[0] = -94.228507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530077457, states[0] = -94.217870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538684913, states[0] = -94.222951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 547703032, states[0] = -94.222585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 557571912, states[0] = -94.214401, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568270565, states[0] = -94.231958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576958498, states[0] = -94.240584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 584039655, states[0] = -94.217880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591948394, states[0] = -94.240695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601604477, states[0] = -94.223967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610362088, states[0] = -94.229252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620099113, states[0] = -94.217050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626638112, states[0] = -94.213677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 634070600, states[0] = -94.237279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642736655, states[0] = -94.238567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650808259, states[0] = -94.213014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657414143, states[0] = -94.077360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665373335, states[0] = -94.214659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671708813, states[0] = -94.213138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680206151, states[0] = -94.215715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685379680, states[0] = -94.228301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 691586322, states[0] = -94.223701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701319964, states[0] = -94.214748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708663181, states[0] = -94.230806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715852810, states[0] = -94.219191, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725432973, states[0] = -94.213911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734288602, states[0] = -94.214735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739814083, states[0] = -94.219565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 747321854, states[0] = -93.827104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754364358, states[0] = -94.228214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760763368, states[0] = -94.220171, states[40]= 0.000001
Saving checkpoint... 
Iteration: 770391449, states[0] = -94.213836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778636982, states[0] = -94.222158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785228476, states[0] = -94.214825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794075473, states[0] = -94.216089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802737822, states[0] = -94.220283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 810740793, states[0] = -94.237669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819109315, states[0] = 12.223512, states[40]= 0.000019
Saving checkpoint... 
Iteration: 825249530, states[0] = -57.378051, states[40]= 0.000155
Saving checkpoint... 
Iteration: 831668597, states[0] = -94.230739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 839054759, states[0] = -94.215987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846798766, states[0] = -94.239617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854661396, states[0] = -94.212041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 862487910, states[0] = -94.224566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871348712, states[0] = -94.227815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 881255065, states[0] = -94.213971, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890623053, states[0] = -94.211931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899488518, states[0] = -94.212441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908460120, states[0] = -94.212521, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917411703, states[0] = -94.212718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923288617, states[0] = -94.213446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930868542, states[0] = -94.239494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939433250, states[0] = -94.103784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947206299, states[0] = -94.213893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 955428942, states[0] = -94.225271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 964362579, states[0] = -94.226828, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972114002, states[0] = 10.486912, states[40]= 0.000029
Saving checkpoint... 
Iteration: 979653210, states[0] = -94.220497, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987716781, states[0] = -94.234825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997029774, states[0] = -94.235953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002382459, states[0] = -94.014146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009976883, states[0] = -94.215653, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1019277536, states[0] = -94.212869, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025739568, states[0] = -94.210633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035451618, states[0] = -94.125813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042926899, states[0] = -94.216013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1049204710, states[0] = -94.213211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057783595, states[0] = -94.217843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065172867, states[0] = -16.108488, states[40]= 0.000755
Saving checkpoint... 
Iteration: 1073403501, states[0] = -94.211701, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1079293685, states[0] = -94.212347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087089241, states[0] = -94.233657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093457094, states[0] = -94.223681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100872129, states[0] = -94.209806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107369043, states[0] = -93.981110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117100020, states[0] = -94.233139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125476943, states[0] = -94.150555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134460696, states[0] = -94.134939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142530331, states[0] = -94.210589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149343160, states[0] = -93.904299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156417200, states[0] = -94.224180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1165724278, states[0] = -94.218026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176194281, states[0] = -24.032085, states[40]= 0.004243
Saving checkpoint... 
Iteration: 1185117290, states[0] = 9.269155, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1194797432, states[0] = -94.237221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1203058452, states[0] = 29.814351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211684434, states[0] = -94.209530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1220093381, states[0] = -94.213013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229356525, states[0] = -94.210915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239038136, states[0] = 33.618908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247322192, states[0] = -94.211010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1253925956, states[0] = -94.208665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263081287, states[0] = 22.485714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270774523, states[0] = -94.216526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277178643, states[0] = -94.211867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285147344, states[0] = -94.230606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293634212, states[0] = -94.221873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301704987, states[0] = -94.208852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309156996, states[0] = -94.230160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318079127, states[0] = -94.232378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324244560, states[0] = -94.227535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332464572, states[0] = -94.137516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340024404, states[0] = -94.212885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1347001933, states[0] = 29.654244, states[40]= 1.573173
Saving checkpoint... 
Iteration: 1356246254, states[0] = -54.679588, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1363707428, states[0] = -94.216952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371267956, states[0] = -78.590701, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1379173044, states[0] = -94.211219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387906055, states[0] = -94.213918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396166710, states[0] = -94.229283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1404216744, states[0] = -33.652467, states[40]= 0.003341
Saving checkpoint... 
Iteration: 1411985717, states[0] = -94.212812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420313320, states[0] = -94.224999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1427764285, states[0] = -94.207823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437479590, states[0] = -94.150731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445524819, states[0] = -94.208547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453482764, states[0] = -94.220652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461674582, states[0] = -94.227250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470919755, states[0] = -94.235243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1479778552, states[0] = -94.234782, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1487030012, states[0] = -94.211823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495654056, states[0] = -94.216965, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.082859
 - CaMKt in component CaMK (millimolar): 0.001353
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.833985
 - nass in component intracellular_ions (millimolar): 7.834136
 - ki in component intracellular_ions (millimolar): 144.002542
 - kss in component intracellular_ions (millimolar): 144.002528
 - cansr in component intracellular_ions (millimolar): 1.770080
 - cajsr in component intracellular_ions (millimolar): 1.771382
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003930
 - hf in component INa (dimensionless): 0.865046
 - hs in component INa (dimensionless): 0.865046
 - j in component INa (dimensionless): 0.865047
 - hsp in component INa (dimensionless): 0.698280
 - jp in component INa (dimensionless): 0.865047
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707033
 - hLp in component INaL (dimensionless): 0.513247
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999150
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999685
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999294
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004264
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000634
 - xs1 in component IKs (dimensionless): 0.019331
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997544
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:14:35 (3868): called boinc_finish(0)

</stderr_txt>
]]>


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