𝕏

Task 54994533

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_649_1
Workunit 26113137
Created 27 Jun 2024, 17:49:18 UTC
Sent 27 Jun 2024, 22:32:21 UTC
Report deadline 30 Jun 2024, 22:32:21 UTC
Received 29 Jun 2024, 0:45:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 2 hours 48 min 34 sec
CPU time 2 hours 18 min 17 sec
Validate state Valid
Credit 44.15
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.29 MB
Peak swap size 5.32 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_649.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_649_1_r862775016_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Drouin_ENDO_4000-conf_649_1_r862775016_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.714489
     * GNaL_b in INaL: 0.005814
     * Gto_b in Ito: 0.090695
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032233
     * GKs_b in IKs: 0.002054
     * GK1_b in IK1: 0.163347
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 74.922210
     * GKb_b in IKb: 0.003938
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031075
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8260211, states[0] = -93.753132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17059118, states[0] = -93.991270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24733588, states[0] = -93.959269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32476988, states[0] = -93.889542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42237458, states[0] = -93.355448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51243101, states[0] = -93.902168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58522426, states[0] = -93.885300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67524967, states[0] = -93.887594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75194793, states[0] = -93.896813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82014533, states[0] = 30.918991, states[40]= 0.012199
Saving checkpoint... 
Iteration: 89981833, states[0] = -93.874969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98445217, states[0] = -93.837860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106612315, states[0] = -93.899924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114451527, states[0] = -93.841698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121580979, states[0] = -93.881358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128034985, states[0] = 28.753953, states[40]= 0.000105
Saving checkpoint... 
Iteration: 137036610, states[0] = -93.899353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145197578, states[0] = -93.892801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154542063, states[0] = -93.883877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161935469, states[0] = -93.873245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169205154, states[0] = -93.892201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177354304, states[0] = -93.886898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184190444, states[0] = -64.697044, states[40]= 0.000019
Saving checkpoint... 
Iteration: 191344679, states[0] = -93.887109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199699563, states[0] = -93.877477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207755357, states[0] = -93.876251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216371744, states[0] = -93.754771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223425631, states[0] = -93.884408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229396752, states[0] = -93.885263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236753970, states[0] = -93.906486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245394974, states[0] = -93.885261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253948488, states[0] = -93.872499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262235431, states[0] = -93.311492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271814510, states[0] = -93.874840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284803846, states[0] = -93.906071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294619299, states[0] = -93.898846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303960463, states[0] = -93.872156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311488215, states[0] = -93.882323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318782085, states[0] = -93.906213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324889384, states[0] = -93.903849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328713279, states[0] = -93.905548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332695955, states[0] = -93.904926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339138379, states[0] = -93.894092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351448728, states[0] = -93.883344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362872018, states[0] = -93.904292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373807509, states[0] = -93.874701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385534427, states[0] = -93.880874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397816236, states[0] = -93.874471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405427823, states[0] = -93.883822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412906970, states[0] = -93.903031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419310308, states[0] = -93.887539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427864286, states[0] = -93.873495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431709217, states[0] = -93.876566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440571322, states[0] = -93.890263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449777966, states[0] = -93.875088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459789294, states[0] = -93.874837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470285529, states[0] = -93.543560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476149659, states[0] = -32.021109, states[40]= 0.001644
Saving checkpoint... 
Iteration: 484859992, states[0] = -93.904328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494396124, states[0] = -93.787380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504889549, states[0] = -93.903380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515816029, states[0] = -93.874172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527333941, states[0] = -93.886468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539400234, states[0] = -93.884316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553148053, states[0] = -93.893161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563318232, states[0] = -93.886901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572379757, states[0] = -93.765650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579129312, states[0] = -93.893835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583316238, states[0] = -93.886917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587827776, states[0] = -93.873763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592752345, states[0] = -93.905530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602733786, states[0] = -93.905303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609300057, states[0] = -93.887402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617799577, states[0] = -93.874229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623546244, states[0] = -93.879952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630797962, states[0] = -93.905256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640126876, states[0] = -14.180919, states[40]= 0.001643
Saving checkpoint... 
Iteration: 645440122, states[0] = -93.882842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654721239, states[0] = -93.904922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663750610, states[0] = -93.875095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674447260, states[0] = -93.835924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686213775, states[0] = -90.314755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700187374, states[0] = -62.015589, states[40]= 0.000029
Saving checkpoint... 
Iteration: 713679778, states[0] = -93.876491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725574001, states[0] = -93.878978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736674057, states[0] = -93.902767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748255291, states[0] = -93.416780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755054166, states[0] = -93.896418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765081507, states[0] = -93.895280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774290555, states[0] = -93.560612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779512002, states[0] = -93.880464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783277574, states[0] = -93.887738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787148216, states[0] = -93.892556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794858445, states[0] = -93.903578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805900444, states[0] = -93.871880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816339541, states[0] = -93.694756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824544133, states[0] = -93.882388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830079723, states[0] = 13.248493, states[40]= 0.001200
Saving checkpoint... 
Iteration: 835041153, states[0] = -93.896743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841674460, states[0] = -93.876282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854009949, states[0] = 29.875056, states[40]= 0.060145
Saving checkpoint... 
Iteration: 867668968, states[0] = -93.876340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881199642, states[0] = -93.890332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894892075, states[0] = -93.902300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909287678, states[0] = -93.887062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922791026, states[0] = -93.904589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936040889, states[0] = 27.171470, states[40]= 0.000137
Saving checkpoint... 
Iteration: 949747965, states[0] = -93.874417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962376419, states[0] = -93.759816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972729167, states[0] = -93.904277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983218665, states[0] = -93.889358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993888857, states[0] = -93.871602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004480179, states[0] = -93.856064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014520855, states[0] = -93.874293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024395191, states[0] = -93.784879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034552205, states[0] = -93.884101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044682219, states[0] = -93.902448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053871798, states[0] = -93.871753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063186027, states[0] = -93.890383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073252405, states[0] = -93.887892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083309105, states[0] = -93.885878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093343008, states[0] = -93.884719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103435091, states[0] = -93.881817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113378022, states[0] = -93.883539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123485456, states[0] = -93.880314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133522770, states[0] = -93.879266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143740034, states[0] = -93.874084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153792718, states[0] = -93.872989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163645755, states[0] = -93.876114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173256962, states[0] = -93.887472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183292533, states[0] = -93.886191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193162872, states[0] = -93.890943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203515057, states[0] = -93.879295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213788326, states[0] = -93.872922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223471371, states[0] = -93.880456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233805876, states[0] = -93.872526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243899329, states[0] = -93.870776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254053332, states[0] = 23.201119, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1264267296, states[0] = -93.469278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273969129, states[0] = -93.869521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283565024, states[0] = -93.877776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293377756, states[0] = -93.883086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303589490, states[0] = -93.877108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313964530, states[0] = -93.869494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323995551, states[0] = -93.868970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333802144, states[0] = -93.872343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344078176, states[0] = 13.879188, states[40]= 0.001114
Saving checkpoint... 
Iteration: 1354337724, states[0] = -93.689475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366752944, states[0] = -93.903555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379729383, states[0] = -93.873703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392495458, states[0] = -93.862780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404324730, states[0] = -93.659365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416924799, states[0] = -93.899830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430314138, states[0] = -93.631779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443077073, states[0] = -93.893725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457044883, states[0] = -93.895000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470774319, states[0] = -93.903306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484296456, states[0] = -93.578628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497541188, states[0] = -93.877844, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.744417
 - CaMKt in component CaMK (millimolar): 0.002040
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.664787
 - nass in component intracellular_ions (millimolar): 6.664909
 - ki in component intracellular_ions (millimolar): 145.196846
 - kss in component intracellular_ions (millimolar): 145.196835
 - cansr in component intracellular_ions (millimolar): 1.811617
 - cajsr in component intracellular_ions (millimolar): 1.811478
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004067
 - hf in component INa (dimensionless): 0.858422
 - hs in component INa (dimensionless): 0.858422
 - j in component INa (dimensionless): 0.858426
 - hsp in component INa (dimensionless): 0.686440
 - jp in component INa (dimensionless): 0.858429
 - mL in component INaL (dimensionless): 0.000062
 - hL in component INaL (dimensionless): 0.697629
 - hLp in component INaL (dimensionless): 0.501495
 - a in component Ito (dimensionless): 0.000674
 - iF in component Ito (dimensionless): 0.999840
 - iS in component Ito (dimensionless): 0.991373
 - ap in component Ito (dimensionless): 0.000343
 - iFp in component Ito (dimensionless): 0.999840
 - iSp in component Ito (dimensionless): 0.996527
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996491
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005035
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008170
 - xs1 in component IKs (dimensionless): 0.041292
 - xs2 in component IKs (dimensionless): 0.000100
 - xk1 in component IK1 (dimensionless): 0.997625
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:44:53 (16180): called boinc_finish(0)

</stderr_txt>
]]>


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