𝕏

Task 54994394

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_749_0
Workunit 26113068
Created 27 Jun 2024, 17:49:18 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 30 Jun 2024, 22:32:22 UTC
Received 28 Jun 2024, 11:40:29 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 3 hours 3 min 56 sec
CPU time 2 hours 50 min 42 sec
Validate state Valid
Credit 42.09
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.26 MB
Peak swap size 5.29 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_749.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_749_0_r1172654014_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_749_0_r1172654014_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 119.604449
     * GNaL_b in INaL: 0.006130
     * Gto_b in Ito: 0.091808
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031073
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.170079
     * Gncx_b in INaCa_i: 0.000978
     * Pnak_b in INaK: 69.974559
     * GKb_b in IKb: 0.003680
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029419
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8667141, states[0] = -89.623505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17769339, states[0] = -94.681492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26583106, states[0] = 1.741647, states[40]= 0.004775
Saving checkpoint... 
Iteration: 36286358, states[0] = -94.685114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44934427, states[0] = -94.817712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53591919, states[0] = -4.338596, states[40]= 0.004016
Saving checkpoint... 
Iteration: 61413449, states[0] = -94.807361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66927938, states[0] = -94.813688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75265502, states[0] = -94.637709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82347470, states[0] = -94.761615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91176460, states[0] = -93.080156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96207432, states[0] = -94.453546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105032887, states[0] = 23.606169, states[40]= 0.001781
Saving checkpoint... 
Iteration: 113408886, states[0] = -94.804483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120269827, states[0] = -94.646988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127600249, states[0] = -11.625176, states[40]= 0.002377
Saving checkpoint... 
Iteration: 133654284, states[0] = -64.479262, states[40]= 0.000010
Saving checkpoint... 
Iteration: 141724829, states[0] = -94.520163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150875013, states[0] = -94.783888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158461299, states[0] = -94.824732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165224867, states[0] = -94.520190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172198726, states[0] = -94.414996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177761273, states[0] = -94.627156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184655311, states[0] = -65.702237, states[40]= 0.000008
Saving checkpoint... 
Iteration: 189641925, states[0] = -51.127894, states[40]= 0.000086
Saving checkpoint... 
Iteration: 198385669, states[0] = -94.790879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205160923, states[0] = -73.133316, states[40]= 0.000002
Saving checkpoint... 
Iteration: 212073951, states[0] = 7.053467, states[40]= 0.004662
Saving checkpoint... 
Iteration: 219838275, states[0] = -94.751761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228215226, states[0] = -94.484187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236925743, states[0] = -94.811748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245461162, states[0] = -94.824331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253857291, states[0] = -94.769605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260202054, states[0] = -94.429800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268970356, states[0] = -94.826822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279642743, states[0] = -51.970138, states[40]= 0.000076
Saving checkpoint... 
Iteration: 288309450, states[0] = -94.716354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298592392, states[0] = -4.696087, states[40]= 0.003945
Saving checkpoint... 
Iteration: 305141130, states[0] = -50.310826, states[40]= 0.000098
Saving checkpoint... 
Iteration: 313902012, states[0] = -94.800033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323110933, states[0] = -21.739233, states[40]= 0.001329
Saving checkpoint... 
Iteration: 329935166, states[0] = -94.815192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336055061, states[0] = 15.602168, states[40]= 0.003324
Saving checkpoint... 
Iteration: 343667618, states[0] = -83.958780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348230653, states[0] = -94.539322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355347535, states[0] = -94.760417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364965423, states[0] = -94.825082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374235409, states[0] = -94.554699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381472020, states[0] = -94.826815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388630076, states[0] = -39.381994, states[40]= 0.000437
Saving checkpoint... 
Iteration: 398421280, states[0] = -94.809161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407065149, states[0] = 11.306815, states[40]= 0.004136
Saving checkpoint... 
Iteration: 415688594, states[0] = -94.341189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424943224, states[0] = -94.817796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430860840, states[0] = -94.771876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437900874, states[0] = -94.798918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445658285, states[0] = -69.457658, states[40]= 0.000004
Saving checkpoint... 
Iteration: 451015770, states[0] = 27.138929, states[40]= 0.008154
Saving checkpoint... 
Iteration: 460725493, states[0] = -94.521189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466567491, states[0] = 10.229809, states[40]= 0.004300
Saving checkpoint... 
Iteration: 475157375, states[0] = -68.269782, states[40]= 0.000005
Saving checkpoint... 
Iteration: 481915369, states[0] = -94.806118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491607860, states[0] = -18.860028, states[40]= 0.001417
Saving checkpoint... 
Iteration: 499476683, states[0] = -94.827541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507059415, states[0] = 13.809088, states[40]= 0.003687
Saving checkpoint... 
Iteration: 513121489, states[0] = -31.409805, states[40]= 0.000994
Saving checkpoint... 
Iteration: 520194721, states[0] = -94.392908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528925109, states[0] = -94.810309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536424484, states[0] = -94.810011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545061014, states[0] = 13.128691, states[40]= 0.003817
Saving checkpoint... 
Iteration: 554780688, states[0] = -94.667516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564055731, states[0] = 15.331983, states[40]= 0.003381
Saving checkpoint... 
Iteration: 572834048, states[0] = -94.745837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580104949, states[0] = -16.093218, states[40]= 0.001648
Saving checkpoint... 
Iteration: 587273607, states[0] = -94.653135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596711530, states[0] = -94.468126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606217591, states[0] = -94.491721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614545102, states[0] = 19.426512, states[40]= 0.002523
Saving checkpoint... 
Iteration: 623730225, states[0] = -94.536775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632418526, states[0] = -94.806984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641550227, states[0] = 17.501976, states[40]= 0.002923
Saving checkpoint... 
Iteration: 651589426, states[0] = -2.408026, states[40]= 0.004365
Saving checkpoint... 
Iteration: 659273819, states[0] = -94.653288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666649746, states[0] = -59.357829, states[40]= 0.000023
Saving checkpoint... 
Iteration: 672862081, states[0] = -94.771924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681806788, states[0] = -94.710951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690726703, states[0] = -94.524486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699789967, states[0] = -94.684005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706357484, states[0] = -94.767957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713912584, states[0] = -94.803856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721420295, states[0] = -94.807430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729726976, states[0] = -94.525275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737623277, states[0] = -33.048500, states[40]= 0.000869
Saving checkpoint... 
Iteration: 744964932, states[0] = -94.823425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752856198, states[0] = -94.766666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760995110, states[0] = -94.830687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769650670, states[0] = -60.367955, states[40]= 0.000020
Saving checkpoint... 
Iteration: 777324170, states[0] = -94.733670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787630566, states[0] = -39.846127, states[40]= 0.000413
Saving checkpoint... 
Iteration: 796926426, states[0] = -94.809798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806079649, states[0] = 3.944145, states[40]= 0.004815
Saving checkpoint... 
Iteration: 815199935, states[0] = -94.418008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825140656, states[0] = -49.823229, states[40]= 0.000105
Saving checkpoint... 
Iteration: 831719740, states[0] = -94.498878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840847026, states[0] = -94.757989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850542290, states[0] = 20.445643, states[40]= 0.002322
Saving checkpoint... 
Iteration: 859140526, states[0] = -49.690242, states[40]= 0.000107
Saving checkpoint... 
Iteration: 869442588, states[0] = -94.815794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878801910, states[0] = -94.702864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883550196, states[0] = 17.514201, states[40]= 0.002921
Saving checkpoint... 
Iteration: 889299295, states[0] = -94.698749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898477737, states[0] = -94.826210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906620980, states[0] = -30.942712, states[40]= 0.001029
Saving checkpoint... 
Iteration: 915744283, states[0] = -94.579396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923569769, states[0] = 9.147160, states[40]= 0.004445
Saving checkpoint... 
Iteration: 932054840, states[0] = 15.691794, states[40]= 0.003306
Saving checkpoint... 
Iteration: 941753869, states[0] = -94.605575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949854356, states[0] = -94.764268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957952855, states[0] = -94.818924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966366734, states[0] = -94.774447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974409721, states[0] = -94.801404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982583812, states[0] = 1.429612, states[40]= 0.004768
Saving checkpoint... 
Iteration: 989977025, states[0] = -94.825668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999869297, states[0] = -94.776276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006038327, states[0] = 21.831509, states[40]= 0.002067
Saving checkpoint... 
Iteration: 1014700560, states[0] = -94.420049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023400535, states[0] = -94.796391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029742611, states[0] = -94.574063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034998029, states[0] = -94.830183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044105625, states[0] = -16.736477, states[40]= 0.001579
Saving checkpoint... 
Iteration: 1053206441, states[0] = -94.445420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061462455, states[0] = -94.821449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070089719, states[0] = -2.624271, states[40]= 0.004330
Saving checkpoint... 
Iteration: 1079139575, states[0] = -48.720330, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1086752705, states[0] = -94.601944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096446979, states[0] = -94.816422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104394700, states[0] = -94.792764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113534944, states[0] = 22.956977, states[40]= 0.001879
Saving checkpoint... 
Iteration: 1122805233, states[0] = -94.706896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132222548, states[0] = -94.507961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141188116, states[0] = -94.331302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149324498, states[0] = -94.732574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155924281, states[0] = -94.807448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163108260, states[0] = -19.235148, states[40]= 0.001398
Saving checkpoint... 
Iteration: 1172743937, states[0] = -94.577356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190393369, states[0] = -94.791639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210169706, states[0] = -87.200629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222225546, states[0] = -94.518290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238361605, states[0] = -94.769271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247662913, states[0] = -76.146938, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1252764672, states[0] = -94.630810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268072727, states[0] = 7.682637, states[40]= 0.004606
Saving checkpoint... 
Iteration: 1290523680, states[0] = 26.058926, states[40]= 0.001850
Saving checkpoint... 
Iteration: 1295784791, states[0] = -94.672299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302909577, states[0] = -94.800018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310557774, states[0] = 14.496147, states[40]= 0.003552
Saving checkpoint... 
Iteration: 1325896023, states[0] = -94.792645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340612071, states[0] = -22.789799, states[40]= 0.001319
Saving checkpoint... 
Iteration: 1357967506, states[0] = -94.821697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379269863, states[0] = -94.641949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390061294, states[0] = 13.009470, states[40]= 0.003840
Saving checkpoint... 
Iteration: 1407725917, states[0] = -94.518840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428288022, states[0] = -94.677639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438082517, states[0] = 2.238723, states[40]= 0.004801
Saving checkpoint... 
Iteration: 1451047781, states[0] = 18.432389, states[40]= 0.002728
Saving checkpoint... 
Iteration: 1472341592, states[0] = -94.750138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486103739, states[0] = -14.934356, states[40]= 0.001797
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.704591
 - CaMKt in component CaMK (millimolar): 0.013097
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.831600
 - nass in component intracellular_ions (millimolar): 6.831700
 - ki in component intracellular_ions (millimolar): 145.044437
 - kss in component intracellular_ions (millimolar): 145.044416
 - cansr in component intracellular_ions (millimolar): 1.691305
 - cajsr in component intracellular_ions (millimolar): 1.649743
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003691
 - hf in component INa (dimensionless): 0.876536
 - hs in component INa (dimensionless): 0.876528
 - j in component INa (dimensionless): 0.876476
 - hsp in component INa (dimensionless): 0.719314
 - jp in component INa (dimensionless): 0.876441
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.701560
 - hLp in component INaL (dimensionless): 0.437546
 - a in component Ito (dimensionless): 0.000632
 - iF in component Ito (dimensionless): 0.999865
 - iS in component Ito (dimensionless): 0.608640
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999865
 - iSp in component Ito (dimensionless): 0.679141
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.915471
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999830
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003185
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.369771
 - xs1 in component IKs (dimensionless): 0.269101
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997389
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:40:20 (1056): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge