𝕏

Task 54994391

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_549_1
Workunit 26113066
Created 27 Jun 2024, 17:49:18 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 30 Jun 2024, 22:32:22 UTC
Received 29 Jun 2024, 3:56:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 2 hours 41 min 6 sec
CPU time 2 hours 28 min 45 sec
Validate state Valid
Credit 41.68
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.28 MB
Peak swap size 5.33 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_549.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_549_1_r1041797857_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_549_1_r1041797857_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 94.190051
     * GNaL_b in INaL: 0.004779
     * Gto_b in Ito: 0.091171
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.033780
     * GKs_b in IKs: 0.001862
     * GK1_b in IK1: 0.147193
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 71.878210
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018642
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9336989, states[0] = -94.912162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20580524, states[0] = 0.949293, states[40]= 0.004163
Saving checkpoint... 
Iteration: 28601186, states[0] = -17.627048, states[40]= 0.001314
Saving checkpoint... 
Iteration: 38883044, states[0] = -94.857276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45428549, states[0] = -94.880678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54279502, states[0] = -94.708295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64522539, states[0] = 25.798141, states[40]= 0.001570
Saving checkpoint... 
Iteration: 75481588, states[0] = -94.891436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84156512, states[0] = -77.574614, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93457997, states[0] = -94.881807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98543089, states[0] = 19.403858, states[40]= 0.001773
Saving checkpoint... 
Iteration: 107118875, states[0] = -34.976361, states[40]= 0.000545
Saving checkpoint... 
Iteration: 116590782, states[0] = -6.150569, states[40]= 0.003291
Saving checkpoint... 
Iteration: 128265600, states[0] = -94.664879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136835227, states[0] = -94.792855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146283420, states[0] = -94.706894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156717134, states[0] = -94.496074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167958729, states[0] = -94.879096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178185828, states[0] = -94.314909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189263342, states[0] = -94.657722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198486576, states[0] = -94.887250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205958169, states[0] = -94.878514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215955520, states[0] = -94.877495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228616706, states[0] = -32.666983, states[40]= 0.000676
Saving checkpoint... 
Iteration: 241592348, states[0] = -7.557058, states[40]= 0.003012
Saving checkpoint... 
Iteration: 245446228, states[0] = -94.873782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258649340, states[0] = -67.785744, states[40]= 0.000004
Saving checkpoint... 
Iteration: 270105866, states[0] = -21.512398, states[40]= 0.001100
Saving checkpoint... 
Iteration: 279977124, states[0] = -94.884166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291182061, states[0] = -94.251173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295692499, states[0] = -94.369926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308704383, states[0] = -94.434913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314891639, states[0] = -94.844304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321869609, states[0] = -94.827109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329558718, states[0] = 13.101749, states[40]= 0.002929
Saving checkpoint... 
Iteration: 339773644, states[0] = -94.683124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349132364, states[0] = -49.065103, states[40]= 0.000090
Saving checkpoint... 
Iteration: 359563747, states[0] = 10.841929, states[40]= 0.003330
Saving checkpoint... 
Iteration: 364106461, states[0] = -22.130823, states[40]= 0.001080
Saving checkpoint... 
Iteration: 374285226, states[0] = -94.709126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382371529, states[0] = -94.828488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389324820, states[0] = -94.777277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397628880, states[0] = -45.338942, states[40]= 0.000153
Saving checkpoint... 
Iteration: 402105959, states[0] = -21.608167, states[40]= 0.001097
Saving checkpoint... 
Iteration: 409691488, states[0] = -94.362766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416834376, states[0] = -94.789736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429967116, states[0] = -94.880427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438666511, states[0] = -90.470936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450696069, states[0] = -94.390497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457242682, states[0] = -94.593765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468855361, states[0] = -94.813102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473734236, states[0] = -94.563725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480887305, states[0] = -94.840475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489205317, states[0] = -94.438730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502027018, states[0] = 24.792539, states[40]= 0.001192
Saving checkpoint... 
Iteration: 514352827, states[0] = -94.810312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524468659, states[0] = -94.880496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535160906, states[0] = -83.788895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544845168, states[0] = -94.801938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552620037, states[0] = -36.085811, states[40]= 0.000486
Saving checkpoint... 
Iteration: 565212302, states[0] = -94.471863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571042380, states[0] = 19.696810, states[40]= 0.001739
Saving checkpoint... 
Iteration: 581051970, states[0] = 15.945162, states[40]= 0.002395
Saving checkpoint... 
Iteration: 593114625, states[0] = -30.530482, states[40]= 0.000794
Saving checkpoint... 
Iteration: 604653052, states[0] = -72.462517, states[40]= 0.000002
Saving checkpoint... 
Iteration: 614230563, states[0] = -94.549178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620508356, states[0] = 26.727254, states[40]= 0.085969
Saving checkpoint... 
Iteration: 628682529, states[0] = -94.259991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636908596, states[0] = -94.853685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643477814, states[0] = -94.882726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647893212, states[0] = -94.843890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658345156, states[0] = -94.801414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669444972, states[0] = -94.871346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677635651, states[0] = -52.594332, states[40]= 0.000053
Saving checkpoint... 
Iteration: 687397781, states[0] = -94.846768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696268762, states[0] = -94.669443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708667669, states[0] = -91.343222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717765567, states[0] = -94.661089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728310752, states[0] = -94.754751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739406971, states[0] = -94.852266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750720462, states[0] = -94.507426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758602091, states[0] = -17.545994, states[40]= 0.001339
Saving checkpoint... 
Iteration: 763266700, states[0] = -94.663844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772405528, states[0] = -94.851253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782783977, states[0] = -94.704616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792768166, states[0] = -94.667488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803103889, states[0] = -19.440439, states[40]= 0.001197
Saving checkpoint... 
Iteration: 813508565, states[0] = 26.701045, states[40]= 0.080108
Saving checkpoint... 
Iteration: 823916596, states[0] = -94.857345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834554351, states[0] = 14.964034, states[40]= 0.002580
Saving checkpoint... 
Iteration: 845121896, states[0] = -38.004494, states[40]= 0.000393
Saving checkpoint... 
Iteration: 855618710, states[0] = -34.718965, states[40]= 0.000560
Saving checkpoint... 
Iteration: 866489336, states[0] = -94.884845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876832037, states[0] = -94.784703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887549899, states[0] = 16.782211, states[40]= 0.002241
Saving checkpoint... 
Iteration: 898060568, states[0] = 12.287775, states[40]= 0.003078
Saving checkpoint... 
Iteration: 908570940, states[0] = 7.309187, states[40]= 0.003837
Saving checkpoint... 
Iteration: 919088648, states[0] = -4.237590, states[40]= 0.003636
Saving checkpoint... 
Iteration: 929061423, states[0] = 11.905069, states[40]= 0.003147
Saving checkpoint... 
Iteration: 939612044, states[0] = -27.883951, states[40]= 0.000917
Saving checkpoint... 
Iteration: 950116239, states[0] = -32.182815, states[40]= 0.000703
Saving checkpoint... 
Iteration: 960540075, states[0] = 20.550835, states[40]= 0.001608
Saving checkpoint... 
Iteration: 971001610, states[0] = 45.131803, states[40]= 0.402659
Saving checkpoint... 
Iteration: 981185638, states[0] = -94.308556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991764406, states[0] = -94.656775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002177669, states[0] = -94.071884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012710040, states[0] = -94.459214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1023312738, states[0] = -94.756581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033930378, states[0] = -94.863348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044501261, states[0] = 46.145451, states[40]= 0.283553
Saving checkpoint... 
Iteration: 1055117353, states[0] = -33.324721, states[40]= 0.000638
Saving checkpoint... 
Iteration: 1065543785, states[0] = 19.167426, states[40]= 0.001825
Saving checkpoint... 
Iteration: 1076339330, states[0] = -94.792815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086910765, states[0] = -94.852923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097273686, states[0] = -94.679798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108240380, states[0] = -94.582912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118678305, states[0] = -94.109217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128929802, states[0] = -94.862651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139441696, states[0] = -94.867893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149088661, states[0] = -4.247816, states[40]= 0.003635
Saving checkpoint... 
Iteration: 1159039318, states[0] = 20.826611, states[40]= 0.001568
Saving checkpoint... 
Iteration: 1169115851, states[0] = -31.784159, states[40]= 0.000725
Saving checkpoint... 
Iteration: 1179476407, states[0] = -94.879918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190041800, states[0] = 19.914428, states[40]= 0.001706
Saving checkpoint... 
Iteration: 1200308154, states[0] = -94.748390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210416139, states[0] = -94.855365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220963331, states[0] = -94.875642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231447514, states[0] = -94.869843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241144617, states[0] = -62.326797, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1250815808, states[0] = -94.760309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260456121, states[0] = -94.872959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269331773, states[0] = -94.782598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278634010, states[0] = -50.827257, states[40]= 0.000069
Saving checkpoint... 
Iteration: 1289022899, states[0] = 25.776623, states[40]= 0.001518
Saving checkpoint... 
Iteration: 1299594748, states[0] = -9.893009, states[40]= 0.002529
Saving checkpoint... 
Iteration: 1310171906, states[0] = -93.244473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320661362, states[0] = -84.435263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330269820, states[0] = -94.669246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340571179, states[0] = 7.185011, states[40]= 0.003852
Saving checkpoint... 
Iteration: 1350978090, states[0] = -94.879637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361719916, states[0] = -94.502294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383615426, states[0] = -31.347686, states[40]= 0.000750
Saving checkpoint... 
Iteration: 1400296174, states[0] = -94.726356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415081489, states[0] = 1.128705, states[40]= 0.004153
Saving checkpoint... 
Iteration: 1425072988, states[0] = 6.220186, states[40]= 0.003953
Saving checkpoint... 
Iteration: 1432533626, states[0] = 22.803614, states[40]= 0.001308
Saving checkpoint... 
Iteration: 1439250110, states[0] = -94.613471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448582866, states[0] = 0.191273, states[40]= 0.004118
Saving checkpoint... 
Iteration: 1457234289, states[0] = -94.559450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464185744, states[0] = -94.307584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472389646, states[0] = -94.837707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480997859, states[0] = -94.884164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489710361, states[0] = -94.458555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499552512, states[0] = 15.725086, states[40]= 0.002437
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.760445
 - CaMKt in component CaMK (millimolar): 0.012787
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.687086
 - nass in component intracellular_ions (millimolar): 6.687186
 - ki in component intracellular_ions (millimolar): 145.186638
 - kss in component intracellular_ions (millimolar): 145.186615
 - cansr in component intracellular_ions (millimolar): 1.682454
 - cajsr in component intracellular_ions (millimolar): 1.640859
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003671
 - hf in component INa (dimensionless): 0.877525
 - hs in component INa (dimensionless): 0.877516
 - j in component INa (dimensionless): 0.877457
 - hsp in component INa (dimensionless): 0.721155
 - jp in component INa (dimensionless): 0.877417
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704417
 - hLp in component INaL (dimensionless): 0.443051
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.616050
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.687585
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.920306
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999855
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003164
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.355478
 - xs1 in component IKs (dimensionless): 0.260208
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997374
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:56:25 (34040): called boinc_finish(0)

</stderr_txt>
]]>


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