𝕏

Task 54994380

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_149_0
Workunit 26113061
Created 27 Jun 2024, 17:49:13 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 30 Jun 2024, 22:32:22 UTC
Received 29 Jun 2024, 0:46:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 2 hours 50 min 21 sec
CPU time 2 hours 19 min 28 sec
Validate state Valid
Credit 41.79
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.26 MB
Peak swap size 5.28 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_149.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_149_0_r1547724124_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Coppini_1000-conf_149_0_r1547724124_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 92.931623
     * GNaL_b in INaL: 0.006890
     * Gto_b in Ito: 0.073803
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030145
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.153677
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 69.323227
     * GKb_b in IKb: 0.003889
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023161
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9847545, states[0] = -94.729644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17153541, states[0] = -59.183920, states[40]= 0.000021
Saving checkpoint... 
Iteration: 25515499, states[0] = 28.682898, states[40]= 0.008129
Saving checkpoint... 
Iteration: 33623281, states[0] = -29.397584, states[40]= 0.001209
Saving checkpoint... 
Iteration: 42946636, states[0] = -94.719353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51443719, states[0] = -94.716097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59533835, states[0] = 24.270870, states[40]= 0.001449
Saving checkpoint... 
Iteration: 67375039, states[0] = -94.674257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74787129, states[0] = -94.557008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82708365, states[0] = -94.303631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91090162, states[0] = -0.932252, states[40]= 0.004445
Saving checkpoint... 
Iteration: 98103421, states[0] = -11.460917, states[40]= 0.002371
Saving checkpoint... 
Iteration: 105343269, states[0] = -94.642070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113354812, states[0] = -94.654104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121069448, states[0] = 10.371566, states[40]= 0.004033
Saving checkpoint... 
Iteration: 129456699, states[0] = -94.716731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137186386, states[0] = -93.216795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143682083, states[0] = -91.217485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151033130, states[0] = 24.534375, states[40]= 0.001425
Saving checkpoint... 
Iteration: 158202841, states[0] = -94.269438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166613339, states[0] = -20.372758, states[40]= 0.001405
Saving checkpoint... 
Iteration: 174483046, states[0] = -94.724320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183065007, states[0] = 12.352551, states[40]= 0.003699
Saving checkpoint... 
Iteration: 191171295, states[0] = -77.311288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198625773, states[0] = -31.121672, states[40]= 0.001112
Saving checkpoint... 
Iteration: 207218580, states[0] = -94.347383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216229440, states[0] = -94.390431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224724390, states[0] = -94.370873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232215849, states[0] = -94.335707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240084381, states[0] = 2.709405, states[40]= 0.004652
Saving checkpoint... 
Iteration: 247234197, states[0] = -94.407837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254101587, states[0] = -9.801219, states[40]= 0.002725
Saving checkpoint... 
Iteration: 261915343, states[0] = -94.697765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269435839, states[0] = -94.707626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273377803, states[0] = -94.673223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278174909, states[0] = -82.713871, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287130300, states[0] = -35.034626, states[40]= 0.000782
Saving checkpoint... 
Iteration: 293716098, states[0] = -94.336484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302459912, states[0] = -94.716724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307516163, states[0] = 28.708136, states[40]= 0.006641
Saving checkpoint... 
Iteration: 316959515, states[0] = -94.716525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327379846, states[0] = -94.674569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336040485, states[0] = 21.964262, states[40]= 0.001797
Saving checkpoint... 
Iteration: 343094344, states[0] = -3.870969, states[40]= 0.004016
Saving checkpoint... 
Iteration: 350327568, states[0] = -94.621083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354261065, states[0] = -94.492091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364528802, states[0] = 25.917091, states[40]= 0.001305
Saving checkpoint... 
Iteration: 375299387, states[0] = -94.577358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384416271, states[0] = -94.697712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394720113, states[0] = -94.352852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402527507, states[0] = 26.301350, states[40]= 0.001301
Saving checkpoint... 
Iteration: 412887732, states[0] = -94.680019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422341300, states[0] = -94.637716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432599983, states[0] = -8.410187, states[40]= 0.003041
Saving checkpoint... 
Iteration: 443894508, states[0] = -94.684528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451030710, states[0] = 25.325049, states[40]= 0.001344
Saving checkpoint... 
Iteration: 455388617, states[0] = -94.680457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463956607, states[0] = -94.714873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470281300, states[0] = -94.541068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479374920, states[0] = -94.670009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487286254, states[0] = -94.551530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494777924, states[0] = -94.533443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506357830, states[0] = -94.654763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518375419, states[0] = -94.670239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531881779, states[0] = -94.675137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539161517, states[0] = -65.010317, states[40]= 0.000010
Saving checkpoint... 
Iteration: 547139652, states[0] = -43.395606, states[40]= 0.000282
Saving checkpoint... 
Iteration: 555867896, states[0] = -94.663775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560513169, states[0] = 28.939597, states[40]= 0.016886
Saving checkpoint... 
Iteration: 569174505, states[0] = -82.100324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579489830, states[0] = -94.724174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591691210, states[0] = -93.959689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596795687, states[0] = -94.569601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600732456, states[0] = -94.399910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611115269, states[0] = -22.064260, states[40]= 0.001400
Saving checkpoint... 
Iteration: 619168978, states[0] = -74.043404, states[40]= 0.000002
Saving checkpoint... 
Iteration: 630567808, states[0] = 11.121364, states[40]= 0.003916
Saving checkpoint... 
Iteration: 637254985, states[0] = -94.473699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645043619, states[0] = 20.817343, states[40]= 0.001995
Saving checkpoint... 
Iteration: 651012138, states[0] = 28.985453, states[40]= 0.023662
Saving checkpoint... 
Iteration: 661901986, states[0] = -94.688333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673940736, states[0] = -94.707908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687409176, states[0] = -94.692473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701663778, states[0] = -67.550758, states[40]= 0.000006
Saving checkpoint... 
Iteration: 707079738, states[0] = 5.304972, states[40]= 0.004585
Saving checkpoint... 
Iteration: 710933134, states[0] = -94.704482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719400251, states[0] = -94.687005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730010141, states[0] = 29.087078, states[40]= 0.046003
Saving checkpoint... 
Iteration: 738476093, states[0] = -94.719831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747648571, states[0] = -51.881182, states[40]= 0.000083
Saving checkpoint... 
Iteration: 751671163, states[0] = -77.106712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 762184946, states[0] = -92.739112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767527329, states[0] = 26.353419, states[40]= 0.001302
Saving checkpoint... 
Iteration: 771442489, states[0] = -94.708195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780484247, states[0] = -94.721872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787123481, states[0] = -29.147861, states[40]= 0.001258
Saving checkpoint... 
Iteration: 798781237, states[0] = -94.539469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804553796, states[0] = 16.952361, states[40]= 0.002765
Saving checkpoint... 
Iteration: 810909571, states[0] = -94.692152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819090354, states[0] = -1.032371, states[40]= 0.004436
Saving checkpoint... 
Iteration: 831675747, states[0] = -83.952155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845772976, states[0] = -94.520352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859823270, states[0] = -94.612993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873175625, states[0] = -83.771570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887196161, states[0] = -94.179527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900966249, states[0] = -94.716156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913296157, states[0] = -94.569071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926750336, states[0] = -94.458532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939590351, states[0] = -1.030057, states[40]= 0.004437
Saving checkpoint... 
Iteration: 950172141, states[0] = -78.537857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960632012, states[0] = -36.527703, states[40]= 0.000665
Saving checkpoint... 
Iteration: 971504995, states[0] = 32.263994, states[40]= 0.258337
Saving checkpoint... 
Iteration: 981725050, states[0] = -94.370062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991901949, states[0] = -94.686853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002210986, states[0] = -94.310636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012330437, states[0] = -94.621898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022765334, states[0] = -94.500483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031601196, states[0] = -9.456309, states[40]= 0.002802
Saving checkpoint... 
Iteration: 1041024166, states[0] = 27.212678, states[40]= 0.001445
Saving checkpoint... 
Iteration: 1050938712, states[0] = -94.705401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061143082, states[0] = -46.604384, states[40]= 0.000181
Saving checkpoint... 
Iteration: 1071264646, states[0] = -94.498470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081375806, states[0] = -94.668062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091448596, states[0] = -94.709181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101580446, states[0] = 4.924665, states[40]= 0.004606
Saving checkpoint... 
Iteration: 1111801054, states[0] = -94.577054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121903286, states[0] = -94.687094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132213593, states[0] = -94.321833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142055944, states[0] = 16.106205, states[40]= 0.002944
Saving checkpoint... 
Iteration: 1151674920, states[0] = -82.716119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161787672, states[0] = -94.551446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171863316, states[0] = -94.656970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182077733, states[0] = 6.359794, states[40]= 0.004514
Saving checkpoint... 
Iteration: 1192339761, states[0] = -94.632528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202046342, states[0] = 19.804401, states[40]= 0.002184
Saving checkpoint... 
Iteration: 1212234015, states[0] = -94.402851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222303713, states[0] = -94.581183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232539835, states[0] = 22.200423, states[40]= 0.001759
Saving checkpoint... 
Iteration: 1242674115, states[0] = -81.500414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1252229692, states[0] = -94.386716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261916702, states[0] = -94.694067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271859750, states[0] = -94.653214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282033223, states[0] = 24.506630, states[40]= 0.001430
Saving checkpoint... 
Iteration: 1292120209, states[0] = -26.337006, states[40]= 0.001387
Saving checkpoint... 
Iteration: 1302271952, states[0] = -94.515855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312149671, states[0] = -52.950121, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1322416680, states[0] = -94.693788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332613078, states[0] = -20.132770, states[40]= 0.001409
Saving checkpoint... 
Iteration: 1344829394, states[0] = -94.619076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357544287, states[0] = 20.570980, states[40]= 0.002040
Saving checkpoint... 
Iteration: 1370045146, states[0] = 20.251649, states[40]= 0.002100
Saving checkpoint... 
Iteration: 1381700268, states[0] = -94.241320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394506295, states[0] = 30.464870, states[40]= 0.167789
Saving checkpoint... 
Iteration: 1408331355, states[0] = -94.621320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421300400, states[0] = -94.574523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434958196, states[0] = -94.711143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447935465, states[0] = -94.702259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461460260, states[0] = -94.711729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475175819, states[0] = -84.047665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487982234, states[0] = -94.718222, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.598361
 - CaMKt in component CaMK (millimolar): 0.013224
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.785640
 - nass in component intracellular_ions (millimolar): 6.785737
 - ki in component intracellular_ions (millimolar): 145.087235
 - kss in component intracellular_ions (millimolar): 145.087215
 - cansr in component intracellular_ions (millimolar): 1.691427
 - cajsr in component intracellular_ions (millimolar): 1.648829
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003731
 - hf in component INa (dimensionless): 0.874634
 - hs in component INa (dimensionless): 0.874625
 - j in component INa (dimensionless): 0.874566
 - hsp in component INa (dimensionless): 0.715770
 - jp in component INa (dimensionless): 0.874526
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.696503
 - hLp in component INaL (dimensionless): 0.428492
 - a in component Ito (dimensionless): 0.000636
 - iF in component Ito (dimensionless): 0.999863
 - iS in component Ito (dimensionless): 0.601102
 - ap in component Ito (dimensionless): 0.000324
 - iFp in component Ito (dimensionless): 0.999863
 - iSp in component Ito (dimensionless): 0.669866
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.910526
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999803
 - jca in component ICaL (dimensionless): 0.999968
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003197
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.381191
 - xs1 in component IKs (dimensionless): 0.277319
 - xs2 in component IKs (dimensionless): 0.000091
 - xk1 in component IK1 (dimensionless): 0.997416
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:46:40 (35300): called boinc_finish(0)

</stderr_txt>
]]>


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