𝕏

Task 54994366

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_449_0
Workunit 26113054
Created 27 Jun 2024, 17:49:13 UTC
Sent 27 Jun 2024, 22:32:22 UTC
Report deadline 1 Jul 2024, 1:25:10 UTC
Received 28 Jun 2024, 11:52:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222976
Run time 3 hours 11 min 32 sec
CPU time 2 hours 58 min 19 sec
Validate state Valid
Credit 45.68
Device peak FLOPS 3.14 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.26 MB
Peak swap size 5.28 MB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_449.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_449_0_r1733691291_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-CLVPET_Block_Ks_95-conf_449_0_r1733691291_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 118.681838
     * GNaL_b in INaL: 0.005629
     * Gto_b in Ito: 0.073991
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033952
     * GKs_b in IKs: 0.000088
     * GK1_b in IK1: 0.157937
     * Gncx_b in INaCa_i: 0.000975
     * Pnak_b in INaK: 74.623087
     * GKb_b in IKb: 0.003766
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025055
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7210894, states[0] = -94.568253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17079033, states[0] = 2.413254, states[40]= 0.005056
Saving checkpoint... 
Iteration: 26887490, states[0] = -94.733722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34164069, states[0] = -87.354093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41777412, states[0] = -94.586813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51150006, states[0] = -66.054122, states[40]= 0.000007
Saving checkpoint... 
Iteration: 60908967, states[0] = -94.720254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68431701, states[0] = -94.728640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74312690, states[0] = -94.633496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83204223, states[0] = -94.349322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89380325, states[0] = -94.698031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96258082, states[0] = -94.527907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101290836, states[0] = -94.596193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107739976, states[0] = -94.477018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116776295, states[0] = -94.567707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122998679, states[0] = -94.742235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131317089, states[0] = -94.634483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139975743, states[0] = -94.736502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148284883, states[0] = -94.583407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157167471, states[0] = -89.507888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164059905, states[0] = 13.258077, states[40]= 0.004680
Saving checkpoint... 
Iteration: 171742732, states[0] = -94.483296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180373896, states[0] = -94.689841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187961854, states[0] = -94.731956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194695186, states[0] = -94.304334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203814522, states[0] = -94.629938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210662131, states[0] = -82.110296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216136681, states[0] = -50.359280, states[40]= 0.000085
Saving checkpoint... 
Iteration: 224709130, states[0] = -94.364977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230397472, states[0] = -94.704747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237112148, states[0] = -25.496691, states[40]= 0.001204
Saving checkpoint... 
Iteration: 244131811, states[0] = -45.187431, states[40]= 0.000182
Saving checkpoint... 
Iteration: 252416219, states[0] = -94.714407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260714373, states[0] = -94.385714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267892796, states[0] = -94.701856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274410685, states[0] = -94.711637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281286427, states[0] = -94.585246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287333591, states[0] = -94.652913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292791189, states[0] = -94.593702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301811260, states[0] = -94.625034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308976211, states[0] = -94.735321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315344689, states[0] = -94.664396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324707474, states[0] = -94.357819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330918639, states[0] = -94.715264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340932139, states[0] = -94.721038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348159515, states[0] = -77.980243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 354339683, states[0] = -94.659214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361375042, states[0] = -94.689873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368408331, states[0] = -94.710138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375509095, states[0] = 29.347965, states[40]= 0.065438
Saving checkpoint... 
Iteration: 385335431, states[0] = -94.654608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394380259, states[0] = -94.693421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403348225, states[0] = -94.667530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409058275, states[0] = 13.980920, states[40]= 0.004575
Saving checkpoint... 
Iteration: 415855976, states[0] = -94.674553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422163950, states[0] = -84.910663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431022002, states[0] = 27.096240, states[40]= 0.003099
Saving checkpoint... 
Iteration: 439379976, states[0] = -94.693085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447237149, states[0] = -94.465149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457479220, states[0] = -94.735596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466094351, states[0] = -7.942720, states[40]= 0.003336
Saving checkpoint... 
Iteration: 473907923, states[0] = -94.709595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482657599, states[0] = -75.085204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492008639, states[0] = 29.505726, states[40]= 0.075888
Saving checkpoint... 
Iteration: 501482712, states[0] = -94.736296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511357664, states[0] = -94.675715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521573986, states[0] = 6.370746, states[40]= 0.005260
Saving checkpoint... 
Iteration: 532055006, states[0] = 15.380871, states[40]= 0.004347
Saving checkpoint... 
Iteration: 540554301, states[0] = 15.676478, states[40]= 0.004295
Saving checkpoint... 
Iteration: 549081736, states[0] = 1.796900, states[40]= 0.005142
Saving checkpoint... 
Iteration: 556077513, states[0] = 4.380704, states[40]= 0.005264
Saving checkpoint... 
Iteration: 564474094, states[0] = -94.733968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571326627, states[0] = -94.644020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576578523, states[0] = 3.784636, states[40]= 0.005249
Saving checkpoint... 
Iteration: 584712657, states[0] = -94.377915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592790308, states[0] = -94.591202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600727113, states[0] = -94.431557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608013986, states[0] = 28.554158, states[40]= 0.014284
Saving checkpoint... 
Iteration: 616066177, states[0] = 10.367596, states[40]= 0.005026
Saving checkpoint... 
Iteration: 625615848, states[0] = -29.122666, states[40]= 0.001050
Saving checkpoint... 
Iteration: 634163434, states[0] = -84.127111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643518688, states[0] = 27.819400, states[40]= 0.004672
Saving checkpoint... 
Iteration: 653901941, states[0] = -94.705856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663321270, states[0] = -94.637174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672244835, states[0] = -94.487539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678849021, states[0] = -94.667409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687720110, states[0] = -94.406151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696168899, states[0] = -90.801469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703088916, states[0] = -3.300278, states[40]= 0.004424
Saving checkpoint... 
Iteration: 711218420, states[0] = -94.399761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720613681, states[0] = -26.996830, states[40]= 0.001154
Saving checkpoint... 
Iteration: 729780436, states[0] = -94.572474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738525853, states[0] = 26.074047, states[40]= 0.002659
Saving checkpoint... 
Iteration: 747080098, states[0] = 2.828966, states[40]= 0.005209
Saving checkpoint... 
Iteration: 756571792, states[0] = 7.545719, states[40]= 0.005221
Saving checkpoint... 
Iteration: 766283451, states[0] = -94.578155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775018640, states[0] = 27.828779, states[40]= 0.004712
Saving checkpoint... 
Iteration: 783928323, states[0] = -94.718077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793860710, states[0] = -94.677400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802227188, states[0] = -94.431172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810709640, states[0] = -94.365108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819608371, states[0] = -21.770755, states[40]= 0.001289
Saving checkpoint... 
Iteration: 824648164, states[0] = -62.956180, states[40]= 0.000011
Saving checkpoint... 
Iteration: 831043495, states[0] = 19.984687, states[40]= 0.003481
Saving checkpoint... 
Iteration: 840013754, states[0] = 28.583135, states[40]= 0.015275
Saving checkpoint... 
Iteration: 849131995, states[0] = -45.375982, states[40]= 0.000177
Saving checkpoint... 
Iteration: 859673518, states[0] = -93.199006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867381792, states[0] = -94.692961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874261734, states[0] = -94.531438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880539313, states[0] = 21.555949, states[40]= 0.003187
Saving checkpoint... 
Iteration: 888241285, states[0] = -94.476410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892934446, states[0] = -94.720208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899859076, states[0] = -94.675691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908155360, states[0] = -71.905201, states[40]= 0.000002
Saving checkpoint... 
Iteration: 916208572, states[0] = -94.360423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924308735, states[0] = -94.619470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931605387, states[0] = -18.796928, states[40]= 0.001424
Saving checkpoint... 
Iteration: 940924003, states[0] = -94.715739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950341293, states[0] = -94.658981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958441591, states[0] = -94.722698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967529514, states[0] = 24.961723, states[40]= 0.002671
Saving checkpoint... 
Iteration: 976403234, states[0] = -94.705539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985876715, states[0] = -94.689090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995283902, states[0] = -94.578278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002423754, states[0] = -94.715436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011597759, states[0] = -11.176049, states[40]= 0.002558
Saving checkpoint... 
Iteration: 1020488994, states[0] = -94.736089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028895608, states[0] = -94.701098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035408709, states[0] = -94.708223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041908281, states[0] = -94.707984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050805491, states[0] = -94.614320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059298097, states[0] = -94.602829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065818857, states[0] = -94.632822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076288354, states[0] = -94.586199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087096213, states[0] = -9.683852, states[40]= 0.002906
Saving checkpoint... 
Iteration: 1095957132, states[0] = -94.727485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103590697, states[0] = -4.741124, states[40]= 0.004115
Saving checkpoint... 
Iteration: 1112413797, states[0] = -94.710507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122489028, states[0] = -94.735774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131549198, states[0] = 17.759151, states[40]= 0.003911
Saving checkpoint... 
Iteration: 1137312129, states[0] = -94.623589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159578680, states[0] = 3.691797, states[40]= 0.005246
Saving checkpoint... 
Iteration: 1175207344, states[0] = -94.354549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184829929, states[0] = -94.645935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205479924, states[0] = -94.733407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217680139, states[0] = -94.084288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222889065, states[0] = -94.696541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246232291, states[0] = -94.446994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264504027, states[0] = 36.361396, states[40]= 0.323840
Saving checkpoint... 
Iteration: 1277365506, states[0] = -94.679770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299615996, states[0] = -29.265603, states[40]= 0.001042
Saving checkpoint... 
Iteration: 1321994956, states[0] = -94.736407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338978341, states[0] = -94.732598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347713924, states[0] = -94.380453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357605081, states[0] = -18.488828, states[40]= 0.001446
Saving checkpoint... 
Iteration: 1370967398, states[0] = -94.729628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376640800, states[0] = -54.786701, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1396955970, states[0] = -94.726173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418531124, states[0] = 24.438998, states[40]= 0.002727
Saving checkpoint... 
Iteration: 1432883414, states[0] = -94.692253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455575693, states[0] = 5.425821, states[40]= 0.005272
Saving checkpoint... 
Iteration: 1465662290, states[0] = -82.336103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483507618, states[0] = 30.014167, states[40]= 0.105804
Saving checkpoint... 
Iteration: 1504855190, states[0] = -48.643385, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1527569214, states[0] = -94.643487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542206313, states[0] = -94.617722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553842493, states[0] = -94.492261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1574169940, states[0] = -73.916131, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1588973282, states[0] = -94.383546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600221333, states[0] = -94.385037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616820758, states[0] = -94.372032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641629417, states[0] = -94.271753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658525499, states[0] = -94.275353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666204985, states[0] = -94.268321, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.125019
 - CaMKt in component CaMK (millimolar): 0.001126
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.342853
 - nass in component intracellular_ions (millimolar): 6.342940
 - ki in component intracellular_ions (millimolar): 145.559524
 - kss in component intracellular_ions (millimolar): 145.559513
 - cansr in component intracellular_ions (millimolar): 1.572297
 - cajsr in component intracellular_ions (millimolar): 1.572248
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003914
 - hf in component INa (dimensionless): 0.865853
 - hs in component INa (dimensionless): 0.865853
 - j in component INa (dimensionless): 0.865855
 - hsp in component INa (dimensionless): 0.699739
 - jp in component INa (dimensionless): 0.865855
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708210
 - hLp in component INaL (dimensionless): 0.514619
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.997741
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999243
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998917
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003051
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001871
 - xs1 in component IKs (dimensionless): 0.021958
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997534
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:52:45 (27068): called boinc_finish(0)

</stderr_txt>
]]>


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