𝕏

Task 54987786

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1
Workunit 26109782
Created 27 Jun 2024, 17:46:16 UTC
Sent 27 Jun 2024, 21:22:04 UTC
Report deadline 30 Jun 2024, 21:22:04 UTC
Received 28 Jun 2024, 7:37:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230699
Run time 43 min 48 sec
CPU time 26 min 14 sec
Validate state Valid
Credit 42.23
Device peak FLOPS 4.42 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.09 MB
Peak swap size 5.29 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 119.369501
     * GNaL_b in INaL: 0.004440
     * Gto_b in Ito: 0.084097
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009899
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.146434
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.481135
     * GKb_b in IKb: 0.003733
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023355
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18190076, states[0] = -32.783870, states[40]= 0.002407
Saving checkpoint... 
Iteration: 37632895, states[0] = -9.166478, states[40]= 0.003108
Saving checkpoint... 
Iteration: 56949223, states[0] = -94.423987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76263816, states[0] = -56.886335, states[40]= 0.000080
Saving checkpoint... 
Iteration: 95447333, states[0] = -94.401866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114617568, states[0] = -0.872046, states[40]= 0.004750
Saving checkpoint... 
Iteration: 132677396, states[0] = -24.507477, states[40]= 0.004957
Saving checkpoint... 
Iteration: 150445012, states[0] = -94.390345, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 119.369501
     * GNaL_b in INaL: 0.004440
     * Gto_b in Ito: 0.084097
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009899
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.146434
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.481135
     * GKb_b in IKb: 0.003733
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023355
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 150445012
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.390345 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 119.369501
     * GNaL_b in INaL: 0.004440
     * Gto_b in Ito: 0.084097
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009899
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.146434
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.481135
     * GKb_b in IKb: 0.003733
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023355
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 150445012
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.390345 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 168140666, states[0] = -10.889789, states[40]= 0.002786
Saving checkpoint... 
Iteration: 185918587, states[0] = -94.368815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204088818, states[0] = 10.161140, states[40]= 0.005324
Saving checkpoint... 
Iteration: 223371958, states[0] = -94.317850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242773143, states[0] = -59.176686, states[40]= 0.000052
Saving checkpoint... 
Iteration: 262251670, states[0] = -49.748447, states[40]= 0.000257
Saving checkpoint... 
Iteration: 275412020, states[0] = -94.361466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292208363, states[0] = -33.863192, states[40]= 0.002342
Saving checkpoint... 
Iteration: 311572063, states[0] = 15.909379, states[40]= 0.004981
Saving checkpoint... 
Iteration: 331161790, states[0] = -19.394027, states[40]= 0.004326
Saving checkpoint... 
Iteration: 350837570, states[0] = -94.259340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370411885, states[0] = -94.360922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390557426, states[0] = 20.547096, states[40]= 0.004309
Saving checkpoint... 
Iteration: 410283523, states[0] = -64.915135, states[40]= 0.000019
Saving checkpoint... 
Iteration: 423995956, states[0] = -94.411294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443499424, states[0] = -94.412538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462908627, states[0] = -94.357705, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-TESZT_Block_Kr_70-conf_242_1_r214386631_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 119.369501
     * GNaL_b in INaL: 0.004440
     * Gto_b in Ito: 0.084097
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.009899
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.146434
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 67.481135
     * GKb_b in IKb: 0.003733
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023355
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 462908627
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.357705 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 481211433, states[0] = -34.875794, states[40]= 0.002081
Saving checkpoint... 
Iteration: 508695681, states[0] = -29.802342, states[40]= 0.003571
Saving checkpoint... 
Iteration: 535300612, states[0] = -80.536279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554302352, states[0] = -82.753756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573441777, states[0] = -94.383436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592381628, states[0] = -94.328597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606027480, states[0] = 29.118450, states[40]= 0.002994
Saving checkpoint... 
Iteration: 625049238, states[0] = 23.025857, states[40]= 0.003830
Saving checkpoint... 
Iteration: 644202808, states[0] = -32.048570, states[40]= 0.002862
Saving checkpoint... 
Iteration: 663188334, states[0] = -27.559485, states[40]= 0.004269
Saving checkpoint... 
Iteration: 682879301, states[0] = -94.325497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702037849, states[0] = 26.386985, states[40]= 0.003226
Saving checkpoint... 
Iteration: 721176174, states[0] = -23.925280, states[40]= 0.005021
Saving checkpoint... 
Iteration: 740486982, states[0] = -94.406921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756016852, states[0] = 30.733590, states[40]= 0.007287
Saving checkpoint... 
Iteration: 776191011, states[0] = -28.369104, states[40]= 0.004026
Saving checkpoint... 
Iteration: 795554334, states[0] = 21.489831, states[40]= 0.004132
Saving checkpoint... 
Iteration: 814478895, states[0] = -94.403223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833889729, states[0] = -94.337473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853495154, states[0] = -94.409904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872579466, states[0] = 13.430828, states[40]= 0.005186
Saving checkpoint... 
Iteration: 892052226, states[0] = 22.127502, states[40]= 0.004007
Saving checkpoint... 
Iteration: 915351060, states[0] = -94.284194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936626933, states[0] = -4.591445, states[40]= 0.004031
Saving checkpoint... 
Iteration: 956047210, states[0] = 23.632992, states[40]= 0.003712
Saving checkpoint... 
Iteration: 973950338, states[0] = -94.387836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991717470, states[0] = -36.926994, states[40]= 0.001620
Saving checkpoint... 
Iteration: 1009532477, states[0] = 27.877901, states[40]= 0.003034
Saving checkpoint... 
Iteration: 1027437264, states[0] = -94.379249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045347114, states[0] = -94.277134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063370934, states[0] = -94.313638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082292725, states[0] = -71.904079, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1101638460, states[0] = -9.787987, states[40]= 0.002946
Saving checkpoint... 
Iteration: 1120786082, states[0] = -66.613852, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1139701391, states[0] = -31.594848, states[40]= 0.003001
Saving checkpoint... 
Iteration: 1159051420, states[0] = 22.370646, states[40]= 0.003960
Saving checkpoint... 
Iteration: 1177085133, states[0] = 11.475862, states[40]= 0.005284
Saving checkpoint... 
Iteration: 1194877335, states[0] = -94.321727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212746742, states[0] = -47.758750, states[40]= 0.000353
Saving checkpoint... 
Iteration: 1230508738, states[0] = 30.783771, states[40]= 0.071055
Saving checkpoint... 
Iteration: 1248638244, states[0] = -9.688940, states[40]= 0.002962
Saving checkpoint... 
Iteration: 1266763564, states[0] = -54.691647, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1285136290, states[0] = -8.795142, states[40]= 0.003125
Saving checkpoint... 
Iteration: 1304290007, states[0] = -69.559560, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1323138285, states[0] = -9.707562, states[40]= 0.002959
Saving checkpoint... 
Iteration: 1342550286, states[0] = 22.711880, states[40]= 0.003892
Saving checkpoint... 
Iteration: 1355830938, states[0] = -94.230035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374893751, states[0] = -94.340536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392725518, states[0] = -39.758998, states[40]= 0.001123
Saving checkpoint... 
Iteration: 1410615636, states[0] = 0.141989, states[40]= 0.004873
Saving checkpoint... 
Iteration: 1428510453, states[0] = 30.689791, states[40]= 0.041456
Saving checkpoint... 
Iteration: 1446527338, states[0] = 29.151382, states[40]= 0.002997
Saving checkpoint... 
Iteration: 1464569940, states[0] = 16.605642, states[40]= 0.004905
Saving checkpoint... 
Iteration: 1482618685, states[0] = -1.094733, states[40]= 0.004695
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.285972
 - CaMKt in component CaMK (millimolar): 0.015596
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.404647
 - nass in component intracellular_ions (millimolar): 6.404726
 - ki in component intracellular_ions (millimolar): 145.504957
 - kss in component intracellular_ions (millimolar): 145.504949
 - cansr in component intracellular_ions (millimolar): 1.589605
 - cajsr in component intracellular_ions (millimolar): 1.523233
 - cai in component intracellular_ions (millimolar): 0.000086
 - m in component INa (dimensionless): 0.003851
 - hf in component INa (dimensionless): 0.868897
 - hs in component INa (dimensionless): 0.868881
 - j in component INa (dimensionless): 0.868779
 - hsp in component INa (dimensionless): 0.705176
 - jp in component INa (dimensionless): 0.868637
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.618009
 - hLp in component INaL (dimensionless): 0.306768
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.465914
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.515824
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.855766
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999135
 - jca in component ICaL (dimensionless): 0.999853
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002699
 - xrf in component IKr (dimensionless): 0.000008
 - xrs in component IKr (dimensionless): 0.533127
 - xs1 in component IKs (dimensionless): 0.357695
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997495
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:37:09 (13244): called boinc_finish(0)

</stderr_txt>
]]>