𝕏

Task 54986428

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_541_1
Workunit 26109106
Created 27 Jun 2024, 17:45:35 UTC
Sent 27 Jun 2024, 21:11:37 UTC
Report deadline 1 Jul 2024, 6:47:37 UTC
Received 30 Jun 2024, 19:20:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239729
Run time 2 hours 55 min 51 sec
CPU time 2 hours 55 min 36 sec
Validate state Valid
Credit 56.00
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.34 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_541.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_541_1_r2042604889_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_541_1_r2042604889_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.381692
     * GNaL_b in INaL: 0.005344
     * Gto_b in Ito: 0.074269
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030912
     * GKs_b in IKs: 0.001902
     * GK1_b in IK1: 0.152071
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.577819
     * GKb_b in IKb: 0.003707
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.019627
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12321122, states[0] = -95.057524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24720028, states[0] = -94.903349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37009452, states[0] = 24.687780, states[40]= 0.060666
Saving checkpoint... 
Iteration: 48992128, states[0] = -95.040331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60961200, states[0] = -95.026187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72927325, states[0] = -95.012524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84909005, states[0] = -95.003060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97257738, states[0] = -94.899522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109684141, states[0] = -94.757419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121682463, states[0] = -94.747868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134029365, states[0] = 19.216387, states[40]= 0.006693
Saving checkpoint... 
Iteration: 146443588, states[0] = -95.002921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158719010, states[0] = -94.832748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170679951, states[0] = -94.726737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183062981, states[0] = 5.931107, states[40]= 0.004927
Saving checkpoint... 
Iteration: 195483818, states[0] = -95.008755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207641618, states[0] = -62.880394, states[40]= 0.000003
Saving checkpoint... 
Iteration: 219608921, states[0] = -29.141364, states[40]= 0.000511
Saving checkpoint... 
Iteration: 231571233, states[0] = 1.887720, states[40]= 0.004591
Saving checkpoint... 
Iteration: 243716317, states[0] = -94.826420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255884876, states[0] = -94.984305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267924052, states[0] = -94.996465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279885325, states[0] = -94.984418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292009827, states[0] = 24.766674, states[40]= 0.055769
Saving checkpoint... 
Iteration: 304425279, states[0] = -94.996723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316414975, states[0] = -94.993951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328523216, states[0] = 21.094919, states[40]= 0.008475
Saving checkpoint... 
Iteration: 340609051, states[0] = -29.253177, states[40]= 0.000505
Saving checkpoint... 
Iteration: 353028118, states[0] = 19.643774, states[40]= 0.006936
Saving checkpoint... 
Iteration: 365439145, states[0] = -94.999996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377862393, states[0] = -94.974875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389857060, states[0] = -94.972363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401816148, states[0] = -94.948240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413855037, states[0] = -94.971365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426080979, states[0] = -3.999375, states[40]= 0.003675
Saving checkpoint... 
Iteration: 438517444, states[0] = 22.564730, states[40]= 0.013895
Saving checkpoint... 
Iteration: 450737141, states[0] = -94.862386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462712004, states[0] = -94.817811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474676726, states[0] = -94.680967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486723702, states[0] = -94.839803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499018209, states[0] = 22.382109, states[40]= 0.012690
Saving checkpoint... 
Iteration: 510985628, states[0] = -95.008395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522972327, states[0] = -95.006323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535191512, states[0] = -94.773731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547167195, states[0] = -93.767991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559128714, states[0] = -48.797951, states[40]= 0.000033
Saving checkpoint... 
Iteration: 571080759, states[0] = -3.846477, states[40]= 0.003705
Saving checkpoint... 
Iteration: 583038785, states[0] = 15.926450, states[40]= 0.005659
Saving checkpoint... 
Iteration: 595011338, states[0] = 24.152277, states[40]= 0.040052
Saving checkpoint... 
Iteration: 606989895, states[0] = -95.008950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618970017, states[0] = -95.005884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630927486, states[0] = -94.997078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642915068, states[0] = -94.993780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655251317, states[0] = -94.883075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667216472, states[0] = -94.826360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679174265, states[0] = -94.611569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691301903, states[0] = -94.937164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703698996, states[0] = -94.790701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715874957, states[0] = -94.980112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727907531, states[0] = -94.991543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740139694, states[0] = -60.662260, states[40]= 0.000004
Saving checkpoint... 
Iteration: 752493355, states[0] = -95.009346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764468915, states[0] = -95.005616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776423758, states[0] = -94.996048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788366078, states[0] = -94.976302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800313259, states[0] = -94.945924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812276353, states[0] = -94.913200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824247824, states[0] = -94.878124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836534352, states[0] = 17.548318, states[40]= 0.006022
Saving checkpoint... 
Iteration: 848942293, states[0] = -95.000419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861358098, states[0] = -94.972595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873769557, states[0] = -94.905706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885998591, states[0] = -95.009963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897982516, states[0] = -95.007718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909960052, states[0] = -95.003959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921929811, states[0] = -94.997491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933903771, states[0] = -94.990277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945918156, states[0] = -94.994465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957897979, states[0] = -94.988410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970256783, states[0] = -94.890162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982638332, states[0] = -59.142493, states[40]= 0.000006
Saving checkpoint... 
Iteration: 994892443, states[0] = -94.986523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006873850, states[0] = -94.979496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018929545, states[0] = -94.997372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030988588, states[0] = -95.008530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043243432, states[0] = -94.871648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055549254, states[0] = 11.822847, states[40]= 0.005230
Saving checkpoint... 
Iteration: 1067901295, states[0] = -94.989422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080068598, states[0] = 3.251646, states[40]= 0.004726
Saving checkpoint... 
Iteration: 1092449832, states[0] = -95.001873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104469530, states[0] = -95.005530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116426153, states[0] = -94.996472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128406323, states[0] = -94.990953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140416489, states[0] = -94.993898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152355972, states[0] = -94.971408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164317197, states[0] = -94.948556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176502849, states[0] = 40.418953, states[40]= 0.116238
Saving checkpoint... 
Iteration: 1188916266, states[0] = -94.993809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201317008, states[0] = -94.948402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213654402, states[0] = -80.391034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225702059, states[0] = -94.796993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237835290, states[0] = -94.960236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249802104, states[0] = -94.937016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261763704, states[0] = -94.898639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273725942, states[0] = -94.843321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285693980, states[0] = -94.779163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297779853, states[0] = -94.916574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310195710, states[0] = -94.783093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322612562, states[0] = -32.622394, states[40]= 0.000351
Saving checkpoint... 
Iteration: 1334856403, states[0] = -94.971515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347090329, states[0] = -11.518542, states[40]= 0.002078
Saving checkpoint... 
Iteration: 1359309013, states[0] = -94.942428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371282060, states[0] = -94.918767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383251386, states[0] = -94.882760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395499519, states[0] = -95.009797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407906922, states[0] = -94.990979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420323279, states[0] = -94.952585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432726514, states[0] = -94.844230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445139946, states[0] = -60.945373, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1457411045, states[0] = -94.992175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469372510, states[0] = -94.978682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481579436, states[0] = -2.949691, states[40]= 0.003877
Saving checkpoint... 
Iteration: 1493915340, states[0] = -94.993380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506058552, states[0] = 3.710038, states[40]= 0.005248
Saving checkpoint... 
Iteration: 1518361606, states[0] = 1.383331, states[40]= 0.005040
Saving checkpoint... 
Iteration: 1530383910, states[0] = -19.404585, states[40]= 0.001111
Saving checkpoint... 
Iteration: 1542753331, states[0] = -94.955714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555125712, states[0] = -95.217900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567501823, states[0] = 48.381634, states[40]= 0.055126
Saving checkpoint... 
Iteration: 1579877101, states[0] = -13.154617, states[40]= 0.002003
Saving checkpoint... 
Iteration: 1592251207, states[0] = -94.927422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604345749, states[0] = -95.256445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616270061, states[0] = -95.115046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628180601, states[0] = -17.188810, states[40]= 0.001362
Saving checkpoint... 
Iteration: 1640103004, states[0] = 40.420934, states[40]= 0.095905
Saving checkpoint... 
Iteration: 1652029807, states[0] = -95.237632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663949995, states[0] = -94.882275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676026532, states[0] = -95.233151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688061736, states[0] = -95.277035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700247541, states[0] = -94.682889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712152572, states[0] = 5.972799, states[40]= 0.005616
Saving checkpoint... 
Iteration: 1724074226, states[0] = -95.289101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735999275, states[0] = -95.185796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748019680, states[0] = -95.222717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760260698, states[0] = -95.084716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772638661, states[0] = -95.250399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784995722, states[0] = -95.306326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797338460, states[0] = 13.502394, states[40]= 0.006501
Saving checkpoint... 
Iteration: 1809454551, states[0] = -95.056455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821477957, states[0] = -95.046456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833723327, states[0] = -94.867209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846067240, states[0] = 3.467423, states[40]= 0.004766
Saving checkpoint... 
Iteration: 1858423852, states[0] = -95.009395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870776408, states[0] = -94.922537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882950213, states[0] = -95.008350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894859872, states[0] = -94.977716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907084215, states[0] = -6.516784, states[40]= 0.003145
Saving checkpoint... 
Iteration: 1918986922, states[0] = -95.010200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930966346, states[0] = -95.006215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942974364, states[0] = -95.007052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955336637, states[0] = -94.961454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967705055, states[0] = -94.803452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980066152, states[0] = 4.445029, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1992424938, states[0] = -94.995929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004714697, states[0] = -94.822375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016632046, states[0] = -52.338579, states[40]= 0.000019
Saving checkpoint... 
Iteration: 2028552019, states[0] = 10.690467, states[40]= 0.005167
Saving checkpoint... 
Iteration: 2040575818, states[0] = -0.680582, states[40]= 0.004259
Saving checkpoint... 
Iteration: 2052936211, states[0] = -94.998391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065303356, states[0] = -94.937572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077654632, states[0] = -80.766287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089929208, states[0] = -94.996665, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.885311
 - CaMKt in component CaMK (millimolar): 0.006792
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.540946
 - nass in component intracellular_ions (millimolar): 6.541006
 - ki in component intracellular_ions (millimolar): 145.438459
 - kss in component intracellular_ions (millimolar): 145.438440
 - cansr in component intracellular_ions (millimolar): 1.307482
 - cajsr in component intracellular_ions (millimolar): 1.269943
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879713
 - hs in component INa (dimensionless): 0.879708
 - j in component INa (dimensionless): 0.879677
 - hsp in component INa (dimensionless): 0.725286
 - jp in component INa (dimensionless): 0.879655
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709457
 - hLp in component INaL (dimensionless): 0.451417
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621959
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696593
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934934
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341362
 - xs1 in component IKs (dimensionless): 0.239619
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:20:34 (212600): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge