𝕏

Task 54986419

Name HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_241_0
Workunit 26109102
Created 27 Jun 2024, 17:45:35 UTC
Sent 27 Jun 2024, 21:11:24 UTC
Report deadline 1 Jul 2024, 6:47:24 UTC
Received 30 Jun 2024, 17:46:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239729
Run time 2 hours 57 min
CPU time 2 hours 56 min 45 sec
Validate state Valid
Credit 57.44
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.34 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_241.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_241_0_r519648841_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627194530078917_ORdGradInc_k_25-Pueyo_APDR-conf_241_0_r519648841_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.303843
     * GNaL_b in INaL: 0.005225
     * Gto_b in Ito: 0.076554
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033382
     * GKs_b in IKs: 0.001779
     * GK1_b in IK1: 0.165021
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 65.952836
     * GKb_b in IKb: 0.003862
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035098
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12305474, states[0] = -94.877876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24266718, states[0] = -94.827361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36288799, states[0] = -94.837018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48625028, states[0] = -52.891105, states[40]= 0.000017
Saving checkpoint... 
Iteration: 60814197, states[0] = -94.844906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72695600, states[0] = -94.698853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84577553, states[0] = -5.011151, states[40]= 0.003502
Saving checkpoint... 
Iteration: 96443523, states[0] = -94.885559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108419377, states[0] = -94.879671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120671604, states[0] = -94.629477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132563911, states[0] = 3.524642, states[40]= 0.004767
Saving checkpoint... 
Iteration: 144514278, states[0] = 22.436936, states[40]= 0.021595
Saving checkpoint... 
Iteration: 156400957, states[0] = -94.873367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168301158, states[0] = -94.827510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180203959, states[0] = -94.708796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192106201, states[0] = -32.210584, states[40]= 0.000351
Saving checkpoint... 
Iteration: 204003948, states[0] = 33.250425, states[40]= 0.151079
Saving checkpoint... 
Iteration: 215900999, states[0] = -94.872895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227780094, states[0] = -94.810320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239668816, states[0] = -94.599846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251553352, states[0] = 8.569419, states[40]= 0.005073
Saving checkpoint... 
Iteration: 263470114, states[0] = -94.886666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275351605, states[0] = -94.855565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287249084, states[0] = -94.777825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299152577, states[0] = -89.794206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311038242, states[0] = 14.910672, states[40]= 0.005598
Saving checkpoint... 
Iteration: 323046732, states[0] = 11.438808, states[40]= 0.005233
Saving checkpoint... 
Iteration: 334991756, states[0] = -94.889373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346884506, states[0] = -94.867843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358790081, states[0] = -94.818600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370698019, states[0] = -94.697024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382602968, states[0] = -28.963868, states[40]= 0.000494
Saving checkpoint... 
Iteration: 394582514, states[0] = -8.906882, states[40]= 0.002647
Saving checkpoint... 
Iteration: 406494403, states[0] = -94.889626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418370313, states[0] = -94.862945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430260184, states[0] = -94.790523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442590630, states[0] = -16.639046, states[40]= 0.001295
Saving checkpoint... 
Iteration: 454912858, states[0] = -94.875716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467034732, states[0] = 16.263466, states[40]= 0.005861
Saving checkpoint... 
Iteration: 479140258, states[0] = -70.366405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491034363, states[0] = 16.401922, states[40]= 0.005894
Saving checkpoint... 
Iteration: 502926156, states[0] = -94.878740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514831348, states[0] = -94.845616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526754943, states[0] = -94.784600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539103699, states[0] = -29.694371, states[40]= 0.000460
Saving checkpoint... 
Iteration: 551441504, states[0] = -94.881790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563785805, states[0] = -94.814966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575960440, states[0] = -94.885007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588033160, states[0] = 16.847826, states[40]= 0.006012
Saving checkpoint... 
Iteration: 600362073, states[0] = -94.859698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612694965, states[0] = -94.690838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625037925, states[0] = 15.035455, states[40]= 0.005619
Saving checkpoint... 
Iteration: 637384248, states[0] = -94.867577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649710553, states[0] = -94.720255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661765543, states[0] = -94.796053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673672840, states[0] = -94.634626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685557466, states[0] = 6.696837, states[40]= 0.004978
Saving checkpoint... 
Iteration: 697471694, states[0] = -94.886594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709782140, states[0] = -94.811747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721758097, states[0] = -94.788044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733812773, states[0] = -94.834636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746149009, states[0] = -84.620573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758477371, states[0] = -94.887328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770378388, states[0] = -94.865565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782402407, states[0] = -94.872828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794684125, states[0] = -94.668291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806572038, states[0] = -1.040188, states[40]= 0.004233
Saving checkpoint... 
Iteration: 818458649, states[0] = -94.884575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830361962, states[0] = -94.859511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842288046, states[0] = -94.816647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854375903, states[0] = -94.864662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866313245, states[0] = -94.834855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878211764, states[0] = -94.722250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890257178, states[0] = -94.786911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902150049, states[0] = -86.311275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914033683, states[0] = 16.655099, states[40]= 0.005959
Saving checkpoint... 
Iteration: 925911419, states[0] = -94.875068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937797722, states[0] = -94.824134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949865019, states[0] = -94.860629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962211270, states[0] = -94.721328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974467710, states[0] = -94.885853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986360192, states[0] = -94.858707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998240087, states[0] = -94.765869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010118243, states[0] = -44.565135, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1022006684, states[0] = 26.362824, states[40]= 0.110897
Saving checkpoint... 
Iteration: 1033888352, states[0] = -94.868619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045763830, states[0] = -94.794033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057661604, states[0] = -94.262760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069552657, states[0] = 8.879032, states[40]= 0.005088
Saving checkpoint... 
Iteration: 1081510952, states[0] = 23.395801, states[40]= 0.042680
Saving checkpoint... 
Iteration: 1093452446, states[0] = -94.883391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105694709, states[0] = -94.690017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118036721, states[0] = 15.504642, states[40]= 0.005701
Saving checkpoint... 
Iteration: 1130374852, states[0] = -94.864124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142546572, states[0] = 11.506572, states[40]= 0.005238
Saving checkpoint... 
Iteration: 1154853107, states[0] = -94.855651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167167503, states[0] = -94.577317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179066590, states[0] = 2.135245, states[40]= 0.004638
Saving checkpoint... 
Iteration: 1190931696, states[0] = -94.879475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202846280, states[0] = -94.852580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215170951, states[0] = -94.621819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227478128, states[0] = -94.887136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1239590538, states[0] = -16.547057, states[40]= 0.001306
Saving checkpoint... 
Iteration: 1251592193, states[0] = -18.197119, states[40]= 0.001128
Saving checkpoint... 
Iteration: 1263559862, states[0] = 5.562937, states[40]= 0.004913
Saving checkpoint... 
Iteration: 1275457072, states[0] = -94.884038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287425944, states[0] = -94.878205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299702881, states[0] = -94.705786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312024171, states[0] = 19.858876, states[40]= 0.007764
Saving checkpoint... 
Iteration: 1324210040, states[0] = -94.718919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336090047, states[0] = -16.059355, states[40]= 0.001367
Saving checkpoint... 
Iteration: 1348194346, states[0] = -94.689138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360518984, states[0] = 21.290910, states[40]= 0.011168
Saving checkpoint... 
Iteration: 1372446948, states[0] = -94.882268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384339888, states[0] = -94.849433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396253832, states[0] = -94.782772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408123283, states[0] = -50.031271, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1420068434, states[0] = 1.110758, states[40]= 0.004525
Saving checkpoint... 
Iteration: 1432318265, states[0] = -94.837615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444463355, states[0] = -94.884914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456352568, states[0] = -94.855230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468264905, states[0] = -94.794889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480418765, states[0] = -94.876481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492298669, states[0] = -94.824488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504174388, states[0] = -95.098610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516435009, states[0] = -95.073227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528691572, states[0] = -95.017372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540841520, states[0] = 10.963652, states[40]= 0.006158
Saving checkpoint... 
Iteration: 1552845874, states[0] = 8.484049, states[40]= 0.005881
Saving checkpoint... 
Iteration: 1564704228, states[0] = -95.059338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576546126, states[0] = 8.218315, states[40]= 0.005864
Saving checkpoint... 
Iteration: 1588590448, states[0] = -32.953153, states[40]= 0.000322
Saving checkpoint... 
Iteration: 1600714165, states[0] = -95.081600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612559933, states[0] = -0.719083, states[40]= 0.004784
Saving checkpoint... 
Iteration: 1624414832, states[0] = -95.084149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636267911, states[0] = -7.692490, states[40]= 0.003255
Saving checkpoint... 
Iteration: 1648135739, states[0] = -95.112946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660225287, states[0] = 18.519217, states[40]= 0.008522
Saving checkpoint... 
Iteration: 1672508265, states[0] = 25.680407, states[40]= 0.076251
Saving checkpoint... 
Iteration: 1684403030, states[0] = -95.066289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696681403, states[0] = -95.024635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708558513, states[0] = 0.278228, states[40]= 0.004949
Saving checkpoint... 
Iteration: 1720417402, states[0] = -95.089188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732269879, states[0] = -9.752872, states[40]= 0.002757
Saving checkpoint... 
Iteration: 1744143440, states[0] = -95.122282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755990925, states[0] = -33.730518, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1767835708, states[0] = -95.113432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780073815, states[0] = -95.007751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792369333, states[0] = -94.997153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804640512, states[0] = -76.820898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816895672, states[0] = -94.909711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829177751, states[0] = -94.680883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841457623, states[0] = -94.903613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853710313, states[0] = -94.733258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865752881, states[0] = -94.791242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877821611, states[0] = -94.846159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890087983, states[0] = -14.286119, states[40]= 0.001619
Saving checkpoint... 
Iteration: 1902359383, states[0] = -94.861104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914616389, states[0] = -42.756871, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1926884762, states[0] = -94.868519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939161134, states[0] = -94.216503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951384512, states[0] = -94.867590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963622134, states[0] = -48.810133, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1975494073, states[0] = -94.888955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987316190, states[0] = -94.836230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999149810, states[0] = -85.953089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011402301, states[0] = -94.872120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023356982, states[0] = -94.856794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035188594, states[0] = -94.676999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047017983, states[0] = 21.542012, states[40]= 0.012452
Saving checkpoint... 
Iteration: 2058847181, states[0] = -94.852441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070723860, states[0] = -94.741601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082559932, states[0] = 5.529094, states[40]= 0.004910
Saving checkpoint... 
Iteration: 2094395405, states[0] = -94.870018, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.765015
 - CaMKt in component CaMK (millimolar): 0.006848
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.777685
 - nass in component intracellular_ions (millimolar): 6.777744
 - ki in component intracellular_ions (millimolar): 145.199419
 - kss in component intracellular_ions (millimolar): 145.199400
 - cansr in component intracellular_ions (millimolar): 1.314985
 - cajsr in component intracellular_ions (millimolar): 1.278006
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003669
 - hf in component INa (dimensionless): 0.877606
 - hs in component INa (dimensionless): 0.877602
 - j in component INa (dimensionless): 0.877575
 - hsp in component INa (dimensionless): 0.721336
 - jp in component INa (dimensionless): 0.877556
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.708228
 - hLp in component INaL (dimensionless): 0.453825
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.628841
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.705149
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940394
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999903
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001624
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327431
 - xs1 in component IKs (dimensionless): 0.227630
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997373
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:46:22 (212462): called boinc_finish(0)

</stderr_txt>
]]>


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