𝕏

Task 54978230

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1
Workunit 26105040
Created 27 Jun 2024, 17:41:42 UTC
Sent 27 Jun 2024, 20:10:00 UTC
Report deadline 30 Jun 2024, 20:10:00 UTC
Received 27 Jun 2024, 23:15:51 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213791
Run time 1 hours 56 min 46 sec
CPU time 1 hours 56 min 46 sec
Validate state Valid
Credit 42.14
Device peak FLOPS 3.69 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1_r569192341_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1_r569192341_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 115.022041
     * GNaL_b in INaL: 0.005713
     * Gto_b in Ito: 0.098953
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032573
     * GKs_b in IKs: 0.002052
     * GK1_b in IK1: 0.170179
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 74.740461
     * GKb_b in IKb: 0.003728
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038677
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14199279, states[0] = -94.224671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27483406, states[0] = -94.125602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41595381, states[0] = -94.104672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54324745, states[0] = -93.892147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67256947, states[0] = -94.104182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81012384, states[0] = 30.137338, states[40]= 0.025878
Saving checkpoint... 
Iteration: 91277537, states[0] = -94.097621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102804202, states[0] = -94.109735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113282658, states[0] = -94.077572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123672673, states[0] = -94.105020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134155203, states[0] = -94.077630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145168865, states[0] = -94.096862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156962995, states[0] = -94.103295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169944985, states[0] = -94.079190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182613678, states[0] = -94.072437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194606686, states[0] = -94.072354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206058142, states[0] = -94.077318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217692579, states[0] = -94.082702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230392287, states[0] = -94.073769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243845381, states[0] = -94.105446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255360432, states[0] = -93.941527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268350323, states[0] = -94.090195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280031673, states[0] = -94.100103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293577740, states[0] = -94.072137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306692658, states[0] = -94.103907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318777122, states[0] = -94.105849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332009395, states[0] = -94.077530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345034412, states[0] = 29.225087, states[40]= 0.000199
Saving checkpoint... 
Iteration: 358495685, states[0] = -94.086386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370329863, states[0] = -94.090569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383685720, states[0] = -94.071255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396121417, states[0] = -8.536130, states[40]= 0.002872
Saving checkpoint... 
Iteration: 409393217, states[0] = -94.088810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422266076, states[0] = -94.074526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435473654, states[0] = -94.053946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448335574, states[0] = -94.090293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460795389, states[0] = -94.080416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474192128, states[0] = -66.333104, states[40]= 0.000016
Saving checkpoint... 
Iteration: 486163229, states[0] = -41.710628, states[40]= 0.000706
Saving checkpoint... 
Iteration: 496084370, states[0] = -94.097995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508175941, states[0] = -94.094972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521640439, states[0] = -94.071346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533319064, states[0] = -94.073859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546794053, states[0] = -94.105489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559390258, states[0] = -94.088664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572597704, states[0] = -94.071562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586060762, states[0] = -94.098651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599653455, states[0] = -94.071143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613250382, states[0] = -94.092504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626416266, states[0] = -94.072869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639867288, states[0] = -94.104361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650393545, states[0] = -94.073025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663773409, states[0] = -94.105318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675610694, states[0] = -94.095880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688797522, states[0] = -94.080044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700534425, states[0] = -94.085004, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1_r569192341_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1_r569192341_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 115.022041
     * GNaL_b in INaL: 0.005713
     * Gto_b in Ito: 0.098953
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032573
     * GKs_b in IKs: 0.002052
     * GK1_b in IK1: 0.170179
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 74.740461
     * GKb_b in IKb: 0.003728
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038677
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 700534425
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.085004 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 713968617, states[0] = -94.069163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724208008, states[0] = -94.093638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737377072, states[0] = -94.073038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748786618, states[0] = -94.080132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760773501, states[0] = -94.080331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 773629598, states[0] = -94.071045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785443204, states[0] = -94.072411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799009153, states[0] = -94.100052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812134140, states[0] = -94.075321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825561763, states[0] = -94.086500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839464546, states[0] = -94.072159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852430710, states[0] = -94.023946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864232330, states[0] = -93.519473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877492102, states[0] = -94.085696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891535803, states[0] = -94.079357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902244624, states[0] = -94.074024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914836786, states[0] = -94.069559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927407928, states[0] = -94.002679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939224346, states[0] = -93.379605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951445701, states[0] = -94.035429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964073841, states[0] = -94.097654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976620216, states[0] = -94.082801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988867250, states[0] = -94.078514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002290957, states[0] = -93.776415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014304930, states[0] = -93.819102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027754124, states[0] = -94.080261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039915830, states[0] = -94.077731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052725832, states[0] = -94.070007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065566192, states[0] = -94.087176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078061741, states[0] = -94.097890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090399768, states[0] = -94.087631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103295145, states[0] = -94.073236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116705204, states[0] = -94.103261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130164567, states[0] = -94.074515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143584104, states[0] = -94.090790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156633817, states[0] = -94.082265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169947626, states[0] = -94.068591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182706140, states[0] = -94.103201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195523575, states[0] = -94.084510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209230312, states[0] = -93.500267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221435874, states[0] = -94.027591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235094590, states[0] = -94.075145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245964459, states[0] = -94.100826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257678173, states[0] = -94.101678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270622083, states[0] = -94.082328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283474773, states[0] = -94.071419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297027183, states[0] = -94.098719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308391881, states[0] = -93.984196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321857823, states[0] = -94.078161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333367484, states[0] = -94.088116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346375618, states[0] = -94.072147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357556708, states[0] = -94.083546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370500009, states[0] = -94.071094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383856266, states[0] = -94.103485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396068881, states[0] = -94.097180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409573350, states[0] = -94.070492, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1_r569192341_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Drouin_ENDO_6000-conf_481_1_r569192341_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 115.022041
     * GNaL_b in INaL: 0.005713
     * Gto_b in Ito: 0.098953
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032573
     * GKs_b in IKs: 0.002052
     * GK1_b in IK1: 0.170179
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 74.740461
     * GKb_b in IKb: 0.003728
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038677
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1409573350
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.070492 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1422988151, states[0] = -94.099812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434194159, states[0] = -68.382688, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1447457604, states[0] = -94.085664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459844378, states[0] = -94.078161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473276644, states[0] = -93.725482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485842270, states[0] = -94.103586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498209150, states[0] = -94.092456, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.943822
 - CaMKt in component CaMK (millimolar): 0.001283
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.536238
 - nass in component intracellular_ions (millimolar): 6.536360
 - ki in component intracellular_ions (millimolar): 145.333386
 - kss in component intracellular_ions (millimolar): 145.333376
 - cansr in component intracellular_ions (millimolar): 1.810902
 - cajsr in component intracellular_ions (millimolar): 1.810821
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003986
 - hf in component INa (dimensionless): 0.862357
 - hs in component INa (dimensionless): 0.862357
 - j in component INa (dimensionless): 0.862358
 - hsp in component INa (dimensionless): 0.693446
 - jp in component INa (dimensionless): 0.862359
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.703182
 - hLp in component INaL (dimensionless): 0.508651
 - a in component Ito (dimensionless): 0.000665
 - iF in component Ito (dimensionless): 0.999846
 - iS in component Ito (dimensionless): 0.999247
 - ap in component Ito (dimensionless): 0.000339
 - iFp in component Ito (dimensionless): 0.999846
 - iSp in component Ito (dimensionless): 0.999709
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999521
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005223
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000554
 - xs1 in component IKs (dimensionless): 0.014712
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997578
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:57:06 (18032): called boinc_finish(0)

</stderr_txt>
]]>


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