𝕏

Task 54969052

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_572_1
Workunit 26100461
Created 27 Jun 2024, 17:37:23 UTC
Sent 27 Jun 2024, 19:18:33 UTC
Report deadline 1 Jul 2024, 4:54:33 UTC
Received 30 Jun 2024, 8:27:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 213933
Run time 2 hours 48 min 15 sec
CPU time 2 hours 22 min 51 sec
Validate state Valid
Credit 57.34
Device peak FLOPS 3.66 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.64 MB
Peak swap size 5.43 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_572.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_572_1_r1788813296_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_572_1_r1788813296_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.942779
     * GNaL_b in INaL: 0.006473
     * Gto_b in Ito: 0.086393
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.029819
     * GKs_b in IKs: 0.002002
     * GK1_b in IK1: 0.179888
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 72.155641
     * GKb_b in IKb: 0.003764
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050503
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10762418, states[0] = -95.195358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25224545, states[0] = -95.108961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39776949, states[0] = -95.145187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54304399, states[0] = -95.152920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68843097, states[0] = -95.165845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83473789, states[0] = -95.193938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96153831, states[0] = -71.973605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110692395, states[0] = -95.002247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125079159, states[0] = 0.128419, states[40]= 0.004192
Saving checkpoint... 
Iteration: 139466123, states[0] = -95.185738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153477905, states[0] = -95.186715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167402948, states[0] = -95.172841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181898896, states[0] = -95.171545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196309219, states[0] = -95.134652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210839276, states[0] = -95.150500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225424267, states[0] = -95.177031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240024639, states[0] = 20.757607, states[40]= 0.007430
Saving checkpoint... 
Iteration: 254187733, states[0] = -94.988055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267585952, states[0] = -3.837282, states[40]= 0.003552
Saving checkpoint... 
Iteration: 281645925, states[0] = -60.330969, states[40]= 0.000005
Saving checkpoint... 
Iteration: 296110698, states[0] = -24.702224, states[40]= 0.000741
Saving checkpoint... 
Iteration: 310605333, states[0] = -19.845923, states[40]= 0.000979
Saving checkpoint... 
Iteration: 325194238, states[0] = -95.001634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339685032, states[0] = -94.979914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353858684, states[0] = -95.158298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368070937, states[0] = 4.303882, states[40]= 0.004600
Saving checkpoint... 
Iteration: 382499388, states[0] = -95.187900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396925915, states[0] = -95.177135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411562171, states[0] = 8.062847, states[40]= 0.004800
Saving checkpoint... 
Iteration: 425300902, states[0] = -95.128874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439846369, states[0] = -95.153294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454256703, states[0] = -95.091562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467577447, states[0] = 1.134860, states[40]= 0.004311
Saving checkpoint... 
Iteration: 482051759, states[0] = 12.078351, states[40]= 0.004933
Saving checkpoint... 
Iteration: 496542021, states[0] = 15.571615, states[40]= 0.005171
Saving checkpoint... 
Iteration: 510780948, states[0] = -95.114055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525302316, states[0] = -95.129754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539868948, states[0] = -95.161893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554056948, states[0] = 10.122122, states[40]= 0.004869
Saving checkpoint... 
Iteration: 568599590, states[0] = -14.664096, states[40]= 0.001483
Saving checkpoint... 
Iteration: 583137004, states[0] = -50.167994, states[40]= 0.000028
Saving checkpoint... 
Iteration: 597777223, states[0] = -95.110900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612387418, states[0] = -95.167675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626953492, states[0] = -95.181915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641300067, states[0] = -95.128190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655471091, states[0] = -95.184439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670087038, states[0] = -4.564280, states[40]= 0.003411
Saving checkpoint... 
Iteration: 684615246, states[0] = -28.835359, states[40]= 0.000542
Saving checkpoint... 
Iteration: 699251773, states[0] = -95.086111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713735886, states[0] = -95.067053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728347498, states[0] = -95.153607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742949355, states[0] = -95.181190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754775300, states[0] = -95.109159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765307748, states[0] = -95.133097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776429378, states[0] = -95.177606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787551086, states[0] = 12.326912, states[40]= 0.004943
Saving checkpoint... 
Iteration: 800513719, states[0] = 22.709164, states[40]= 0.024466
Saving checkpoint... 
Iteration: 814587477, states[0] = -4.865955, states[40]= 0.003351
Saving checkpoint... 
Iteration: 828929689, states[0] = -95.177636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843426580, states[0] = -95.177013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857327714, states[0] = -95.144333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869864905, states[0] = -95.160289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884328821, states[0] = -95.144881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898824387, states[0] = -95.142580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913439492, states[0] = -95.179414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928054958, states[0] = 10.881472, states[40]= 0.004892
Saving checkpoint... 
Iteration: 941833127, states[0] = -95.146981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956418733, states[0] = -95.175317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970995454, states[0] = -95.187155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985586076, states[0] = -3.917195, states[40]= 0.003536
Saving checkpoint... 
Iteration: 1000259312, states[0] = -95.093952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014717452, states[0] = -95.040697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028489076, states[0] = -95.186426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041273447, states[0] = -95.107374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055475966, states[0] = -95.184844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069939527, states[0] = -95.179331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084551990, states[0] = 11.992913, states[40]= 0.004930
Saving checkpoint... 
Iteration: 1099193772, states[0] = -95.000299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113875810, states[0] = -95.163848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128206483, states[0] = -95.022879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142288284, states[0] = -95.119476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156737082, states[0] = -95.068342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171461058, states[0] = -95.182748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186141527, states[0] = -55.186150, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1200885582, states[0] = -95.166804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215383252, states[0] = -95.166104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230045959, states[0] = 14.187061, states[40]= 0.005043
Saving checkpoint... 
Iteration: 1244723974, states[0] = -95.050353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259417142, states[0] = -95.174798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274034314, states[0] = 18.110132, states[40]= 0.005663
Saving checkpoint... 
Iteration: 1288634706, states[0] = -47.698229, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1303311576, states[0] = -95.135131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317924120, states[0] = -95.176244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332248361, states[0] = -95.081913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346895225, states[0] = -95.169429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361643939, states[0] = -57.963868, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1376419986, states[0] = -95.175346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391087867, states[0] = -5.137250, states[40]= 0.003296
Saving checkpoint... 
Iteration: 1405684346, states[0] = -94.976675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419818858, states[0] = -95.139279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434474579, states[0] = -95.184451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449081026, states[0] = -0.814377, states[40]= 0.004059
Saving checkpoint... 
Iteration: 1461686448, states[0] = -94.983823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476106883, states[0] = -21.247811, states[40]= 0.000900
Saving checkpoint... 
Iteration: 1490854649, states[0] = -95.156087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505526310, states[0] = -59.823714, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1519725476, states[0] = -95.340085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534048737, states[0] = -94.644625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548439437, states[0] = -87.019466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562978366, states[0] = -95.413746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577606576, states[0] = -95.341228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592276768, states[0] = -95.289228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606869634, states[0] = -3.096412, states[40]= 0.004192
Saving checkpoint... 
Iteration: 1621481099, states[0] = -95.422793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636069886, states[0] = -95.276561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649663463, states[0] = -95.410498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662751392, states[0] = -95.111924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677273693, states[0] = -95.418637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691958787, states[0] = -95.406947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706599410, states[0] = -95.334988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718972755, states[0] = -95.418073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1733286304, states[0] = -95.311625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747761956, states[0] = -95.409674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762416249, states[0] = -95.360501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776981835, states[0] = -14.328808, states[40]= 0.001742
Saving checkpoint... 
Iteration: 1791556647, states[0] = -95.405144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805582470, states[0] = -4.038510, states[40]= 0.003647
Saving checkpoint... 
Iteration: 1819104395, states[0] = -21.451408, states[40]= 0.000897
Saving checkpoint... 
Iteration: 1833024221, states[0] = 20.573183, states[40]= 0.007513
Saving checkpoint... 
Iteration: 1847381824, states[0] = -95.179873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861009923, states[0] = 23.446293, states[40]= 0.055185
Saving checkpoint... 
Iteration: 1875399672, states[0] = -95.176593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888005646, states[0] = 27.384256, states[40]= 0.132667
Saving checkpoint... 
Iteration: 1898912914, states[0] = -95.176603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907371935, states[0] = -95.164543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914402439, states[0] = -95.172930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920732763, states[0] = -95.063901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923943537, states[0] = -95.181005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929471625, states[0] = -95.185016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932834602, states[0] = -95.148245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937472657, states[0] = -95.184878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943229759, states[0] = -95.058981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948665055, states[0] = -90.674979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959508444, states[0] = 24.183511, states[40]= 0.077225
Saving checkpoint... 
Iteration: 1973944613, states[0] = -95.179996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988447742, states[0] = -95.180391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002994294, states[0] = -95.186540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014900999, states[0] = -95.170609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027607281, states[0] = -21.612852, states[40]= 0.000881
Saving checkpoint... 
Iteration: 2042149901, states[0] = -65.382276, states[40]= 0.000002
Saving checkpoint... 
Iteration: 2056861816, states[0] = -95.158471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071380406, states[0] = -95.164719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085267382, states[0] = -95.101209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099744650, states[0] = -95.077104, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.062815
 - CaMKt in component CaMK (millimolar): 0.006887
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.496165
 - nass in component intracellular_ions (millimolar): 6.496224
 - ki in component intracellular_ions (millimolar): 145.485173
 - kss in component intracellular_ions (millimolar): 145.485153
 - cansr in component intracellular_ions (millimolar): 1.297713
 - cajsr in component intracellular_ions (millimolar): 1.259229
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003560
 - hf in component INa (dimensionless): 0.882766
 - hs in component INa (dimensionless): 0.882762
 - j in component INa (dimensionless): 0.882737
 - hsp in component INa (dimensionless): 0.731065
 - jp in component INa (dimensionless): 0.882721
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713095
 - hLp in component INaL (dimensionless): 0.453700
 - a in component Ito (dimensionless): 0.000617
 - iF in component Ito (dimensionless): 0.999873
 - iS in component Ito (dimensionless): 0.616688
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999873
 - iSp in component Ito (dimensionless): 0.690788
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930617
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999868
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001543
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341433
 - xs1 in component IKs (dimensionless): 0.252001
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997294
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:26:27 (8696): called boinc_finish(0)

</stderr_txt>
]]>


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