𝕏

Task 54967028

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70_1
Workunit 26099453
Created 27 Jun 2024, 17:36:26 UTC
Sent 27 Jun 2024, 19:01:21 UTC
Report deadline 30 Jun 2024, 19:01:21 UTC
Received 28 Jun 2024, 19:43:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236149
Run time 1 hours 27 min 21 sec
CPU time 1 hours 25 min 10 sec
Validate state Valid
Credit 41.58
Device peak FLOPS 5.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.19 MB
Peak swap size 3.69 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70_1_r206828494_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70_1_r206828494_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.635627
     * GNaL_b in INaL: 0.004458
     * Gto_b in Ito: 0.083149
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030835
     * GKs_b in IKs: 0.001999
     * GK1_b in IK1: 0.178649
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 70.045128
     * GKb_b in IKb: 0.003709
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042215
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9154247, states[0] = -84.982048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18046020, states[0] = 15.084669, states[40]= 0.000066
Saving checkpoint... 
Iteration: 31740604, states[0] = -12.045425, states[40]= 0.000406
Saving checkpoint... 
Iteration: 45528680, states[0] = 23.541793, states[40]= 0.000015
Saving checkpoint... 
Iteration: 59560360, states[0] = -0.087429, states[40]= 0.000195
Saving checkpoint... 
Iteration: 73048371, states[0] = 8.987818, states[40]= 0.000043
Saving checkpoint... 
Iteration: 86417974, states[0] = -36.793977, states[40]= 0.000203
Saving checkpoint... 
Iteration: 100471450, states[0] = -84.833245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 114281756, states[0] = -82.431026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 127904006, states[0] = -23.770140, states[40]= 0.000205
Saving checkpoint... 
Iteration: 136556058, states[0] = -4.548190, states[40]= 0.000221
Saving checkpoint... 
Iteration: 149861422, states[0] = 17.445775, states[40]= 0.000004
Saving checkpoint... 
Iteration: 163516231, states[0] = 23.527569, states[40]= 0.000017
Saving checkpoint... 
Iteration: 177202792, states[0] = 10.137729, states[40]= 0.000029
Saving checkpoint... 
Iteration: 190953552, states[0] = -84.682381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 199734926, states[0] = -30.441469, states[40]= 0.000222
Saving checkpoint... 
Iteration: 213385532, states[0] = -9.622811, states[40]= 0.000237
Saving checkpoint... 
Iteration: 222333451, states[0] = 28.189340, states[40]= 0.000663
Saving checkpoint... 
Iteration: 231447879, states[0] = -84.630526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240168523, states[0] = 26.800275, states[40]= 0.000185
Saving checkpoint... 
Iteration: 253642302, states[0] = 31.380539, states[40]= 0.670972
Saving checkpoint... 
Iteration: 267440109, states[0] = -84.386241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 281475784, states[0] = 29.652101, states[40]= 0.610798
Saving checkpoint... 
Iteration: 290257958, states[0] = -75.931965, states[40]= 0.000004
Saving checkpoint... 
Iteration: 304116508, states[0] = -84.810824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317885153, states[0] = -24.052080, states[40]= 0.000203
Saving checkpoint... 
Iteration: 331518210, states[0] = 11.936455, states[40]= 0.000019
Saving checkpoint... 
Iteration: 345467770, states[0] = 33.121805, states[40]= 1.062103
Saving checkpoint... 
Iteration: 354435541, states[0] = -84.620826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 368661657, states[0] = 23.908630, states[40]= 0.000022
Saving checkpoint... 
Iteration: 376925177, states[0] = -83.720873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390546866, states[0] = -27.265044, states[40]= 0.000217
Saving checkpoint... 
Iteration: 404150937, states[0] = 27.304796, states[40]= 0.000284
Saving checkpoint... 
Iteration: 417466315, states[0] = 28.363983, states[40]= 0.137728
Saving checkpoint... 
Iteration: 431151125, states[0] = 26.037608, states[40]= 0.000100
Saving checkpoint... 
Iteration: 444765594, states[0] = -84.749656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458195951, states[0] = -11.827706, states[40]= 0.000229
Saving checkpoint... 
Iteration: 471383077, states[0] = -41.974579, states[40]= 0.000143


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70_1_r206828494_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Schmidt_333-conf_70_1_r206828494_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.635627
     * GNaL_b in INaL: 0.004458
     * Gto_b in Ito: 0.083149
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.030835
     * GKs_b in IKs: 0.001999
     * GK1_b in IK1: 0.178649
     * Gncx_b in INaCa_i: 0.000953
     * Pnak_b in INaK: 70.045128
     * GKb_b in IKb: 0.003709
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042215
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 471383077
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -41.974579 (After loading)
 - states[40]: 0.000143 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 485293593, states[0] = 28.595571, states[40]= 0.104874
Saving checkpoint... 
Iteration: 498878746, states[0] = -39.885581, states[40]= 0.000164
Saving checkpoint... 
Iteration: 512260675, states[0] = -84.773600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525761174, states[0] = -84.798634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 534929623, states[0] = -84.832616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543063257, states[0] = -71.514834, states[40]= 0.000007
Saving checkpoint... 
Iteration: 557011871, states[0] = -2.070434, states[40]= 0.000188
Saving checkpoint... 
Iteration: 570041890, states[0] = -44.625276, states[40]= 0.000118
Saving checkpoint... 
Iteration: 579105503, states[0] = -84.974888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587860376, states[0] = -27.128556, states[40]= 0.000217
Saving checkpoint... 
Iteration: 601654478, states[0] = 14.272407, states[40]= 0.000010
Saving checkpoint... 
Iteration: 614668099, states[0] = 2.687546, states[40]= 0.000113
Saving checkpoint... 
Iteration: 628537393, states[0] = -46.396234, states[40]= 0.000102
Saving checkpoint... 
Iteration: 642108211, states[0] = 28.060434, states[40]= 0.320032
Saving checkpoint... 
Iteration: 655344120, states[0] = -13.573259, states[40]= 0.000220
Saving checkpoint... 
Iteration: 668625187, states[0] = 27.017923, states[40]= 0.000221
Saving checkpoint... 
Iteration: 681871976, states[0] = -55.225380, states[40]= 0.000045
Saving checkpoint... 
Iteration: 695825679, states[0] = 3.579549, states[40]= 0.000099
Saving checkpoint... 
Iteration: 709445411, states[0] = 29.614924, states[40]= 0.006025
Saving checkpoint... 
Iteration: 723514502, states[0] = -28.524105, states[40]= 0.000220
Saving checkpoint... 
Iteration: 737508582, states[0] = -22.226841, states[40]= 0.000197
Saving checkpoint... 
Iteration: 743519256, states[0] = -37.625171, states[40]= 0.000184
Saving checkpoint... 
Iteration: 757044116, states[0] = -75.089255, states[40]= 0.000004
Saving checkpoint... 
Iteration: 770988644, states[0] = -0.093433, states[40]= 0.000158
Saving checkpoint... 
Iteration: 784797627, states[0] = 17.638127, states[40]= 0.000004
Saving checkpoint... 
Iteration: 798444573, states[0] = 27.421474, states[40]= 0.000312
Saving checkpoint... 
Iteration: 812151625, states[0] = -0.540873, states[40]= 0.000165
Saving checkpoint... 
Iteration: 825654061, states[0] = -4.863260, states[40]= 0.000221
Saving checkpoint... 
Iteration: 839548827, states[0] = -84.266672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853222729, states[0] = -84.685877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 862631018, states[0] = 12.474317, states[40]= 0.000016
Saving checkpoint... 
Iteration: 876325354, states[0] = -18.385023, states[40]= 0.000196
Saving checkpoint... 
Iteration: 890158623, states[0] = -20.279253, states[40]= 0.000194
Saving checkpoint... 
Iteration: 903913607, states[0] = 29.511065, states[40]= 0.594660
Saving checkpoint... 
Iteration: 917667537, states[0] = -36.320449, states[40]= 0.000195
Saving checkpoint... 
Iteration: 931338713, states[0] = -44.085506, states[40]= 0.000123
Saving checkpoint... 
Iteration: 945242456, states[0] = 30.154565, states[40]= 0.671837
Saving checkpoint... 
Iteration: 954393409, states[0] = -84.871031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 968447350, states[0] = 16.749143, states[40]= 0.000005
Saving checkpoint... 
Iteration: 977488097, states[0] = -27.118115, states[40]= 0.000216
Saving checkpoint... 
Iteration: 991446781, states[0] = 15.637766, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1005407185, states[0] = 28.269878, states[40]= 0.155540
Saving checkpoint... 
Iteration: 1019283413, states[0] = 11.492015, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1033373285, states[0] = -84.708880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042547874, states[0] = -84.827393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1056827308, states[0] = -45.581903, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1071196013, states[0] = -84.523003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080642101, states[0] = -23.853608, states[40]= 0.000203
Saving checkpoint... 
Iteration: 1095005323, states[0] = -66.980577, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1109771197, states[0] = 13.698626, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1123887418, states[0] = -84.967683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1138299219, states[0] = -18.457666, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1152654888, states[0] = -50.654916, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1166896371, states[0] = 29.618848, states[40]= 0.020727
Saving checkpoint... 
Iteration: 1181433306, states[0] = 11.891608, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1195611222, states[0] = 1.548332, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1200627386, states[0] = -19.990517, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1209976841, states[0] = -43.173451, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1224189318, states[0] = -84.724362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1238752067, states[0] = 17.750924, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1248264290, states[0] = 8.697249, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1263310902, states[0] = -51.189512, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1277881450, states[0] = 28.749816, states[40]= 0.088205
Saving checkpoint... 
Iteration: 1292316743, states[0] = -63.556235, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1307406118, states[0] = 21.180927, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1322343035, states[0] = -84.665802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337737437, states[0] = 20.593889, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1352248842, states[0] = 12.400026, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1361668529, states[0] = -84.564443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1376542827, states[0] = 29.684514, states[40]= 0.015574
Saving checkpoint... 
Iteration: 1386606923, states[0] = -17.285784, states[40]= 0.000200
Saving checkpoint... 
Iteration: 1402021551, states[0] = -84.905856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417240334, states[0] = 13.787935, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1432140074, states[0] = -69.827910, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1447588561, states[0] = -1.023910, states[40]= 0.000172
Saving checkpoint... 
Iteration: 1457342940, states[0] = -84.836480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472512275, states[0] = -84.879288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483030047, states[0] = 29.412130, states[40]= 0.034874
Saving checkpoint... 
Iteration: 1498581554, states[0] = 0.945166, states[40]= 0.000141
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.820568
 - CaMKt in component CaMK (millimolar): 0.220538
 - cass in component intracellular_ions (millimolar): 0.000173
 - nai in component intracellular_ions (millimolar): 7.266705
 - nass in component intracellular_ions (millimolar): 7.267055
 - ki in component intracellular_ions (millimolar): 143.823945
 - kss in component intracellular_ions (millimolar): 143.823911
 - cansr in component intracellular_ions (millimolar): 3.349609
 - cajsr in component intracellular_ions (millimolar): 1.897869
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009984
 - hf in component INa (dimensionless): 0.583200
 - hs in component INa (dimensionless): 0.582236
 - j in component INa (dimensionless): 0.553099
 - hsp in component INa (dimensionless): 0.331062
 - jp in component INa (dimensionless): 0.511350
 - mL in component INaL (dimensionless): 0.000336
 - hL in component INaL (dimensionless): 0.182679
 - hLp in component INaL (dimensionless): 0.074544
 - a in component Ito (dimensionless): 0.001230
 - iF in component Ito (dimensionless): 0.999234
 - iS in component Ito (dimensionless): 0.129867
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999235
 - iSp in component Ito (dimensionless): 0.145141
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.672843
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.927075
 - jca in component ICaL (dimensionless): 0.909348
 - ffp in component ICaL (dimensionless): 0.998842
 - fcafp in component ICaL (dimensionless): 0.999934
 - nca in component ICaL (dimensionless): 0.043091
 - xrf in component IKr (dimensionless): 0.102794
 - xrs in component IKr (dimensionless): 0.873391
 - xs1 in component IKs (dimensionless): 0.574237
 - xs2 in component IKs (dimensionless): 0.007479
 - xk1 in component IK1 (dimensionless): 0.996741
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:43:09 (412663): called boinc_finish(0)

</stderr_txt>
]]>