𝕏

Task 54966874

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_970_1
Workunit 26099376
Created 27 Jun 2024, 17:36:21 UTC
Sent 27 Jun 2024, 19:01:21 UTC
Report deadline 30 Jun 2024, 19:01:21 UTC
Received 28 Jun 2024, 17:39:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236149
Run time 1 hours 28 min 26 sec
CPU time 1 hours 25 min 53 sec
Validate state Valid
Credit 41.94
Device peak FLOPS 5.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 1.75 MB
Peak swap size 3.69 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_970.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_970_1_r795240777_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_970_1_r795240777_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.633236
     * GNaL_b in INaL: 0.005008
     * Gto_b in Ito: 0.080786
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030276
     * GKs_b in IKs: 0.001764
     * GK1_b in IK1: 0.156546
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 74.928169
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053754
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9129765, states[0] = -87.897862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23080383, states[0] = -47.191391, states[40]= 0.000051
Saving checkpoint... 
Iteration: 32081373, states[0] = -49.493618, states[40]= 0.000037
Saving checkpoint... 
Iteration: 41141028, states[0] = -87.885871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55392892, states[0] = -22.172171, states[40]= 0.001010
Saving checkpoint... 
Iteration: 69247906, states[0] = -54.113369, states[40]= 0.000018
Saving checkpoint... 
Iteration: 82881860, states[0] = -10.497886, states[40]= 0.003061
Saving checkpoint... 
Iteration: 97087578, states[0] = -67.885955, states[40]= 0.000002
Saving checkpoint... 
Iteration: 110909576, states[0] = -52.837881, states[40]= 0.000022
Saving checkpoint... 
Iteration: 120043967, states[0] = -9.345070, states[40]= 0.003381
Saving checkpoint... 
Iteration: 133532305, states[0] = 1.857291, states[40]= 0.006274
Saving checkpoint... 
Iteration: 147271622, states[0] = -87.652578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161111159, states[0] = -87.796429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170456982, states[0] = -87.860719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184466965, states[0] = -87.898443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198482356, states[0] = 38.874994, states[40]= 0.070704
Saving checkpoint... 
Iteration: 212000677, states[0] = 17.799628, states[40]= 0.010854
Saving checkpoint... 
Iteration: 225976577, states[0] = -87.936566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239863666, states[0] = -7.226415, states[40]= 0.003994
Saving checkpoint... 
Iteration: 253700554, states[0] = -13.787805, states[40]= 0.002248
Saving checkpoint... 
Iteration: 267344495, states[0] = 8.020048, states[40]= 0.007287
Saving checkpoint... 
Iteration: 276163195, states[0] = 16.624302, states[40]= 0.009799
Saving checkpoint... 
Iteration: 289692890, states[0] = -8.329690, states[40]= 0.003672
Saving checkpoint... 
Iteration: 303409769, states[0] = -82.822735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317449319, states[0] = -87.884626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331075444, states[0] = -84.547856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344730775, states[0] = -69.996772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358000494, states[0] = 9.152005, states[40]= 0.007473
Saving checkpoint... 
Iteration: 371860879, states[0] = -21.497551, states[40]= 0.001073
Saving checkpoint... 
Iteration: 385819703, states[0] = 16.187315, states[40]= 0.009517
Saving checkpoint... 
Iteration: 399558382, states[0] = -69.584035, states[40]= 0.000002
Saving checkpoint... 
Iteration: 408856107, states[0] = -19.984538, states[40]= 0.001232
Saving checkpoint... 
Iteration: 422386356, states[0] = -64.567655, states[40]= 0.000004
Saving checkpoint... 
Iteration: 430906490, states[0] = -87.409590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444944369, states[0] = -87.908386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458938646, states[0] = -87.895410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472025387, states[0] = -32.446021, states[40]= 0.000382
Saving checkpoint... 
Iteration: 485814803, states[0] = 13.228835, states[40]= 0.008326
Saving checkpoint... 
Iteration: 494959695, states[0] = 23.549080, states[40]= 0.054309
Saving checkpoint... 
Iteration: 508114684, states[0] = -87.935399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517467408, states[0] = 19.111823, states[40]= 0.012954
Saving checkpoint... 
Iteration: 531320869, states[0] = 5.957850, states[40]= 0.006963
Saving checkpoint... 
Iteration: 545418080, states[0] = -87.855126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559214904, states[0] = -79.324785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573192629, states[0] = -47.136587, states[40]= 0.000054
Saving checkpoint... 
Iteration: 581855318, states[0] = -42.843283, states[40]= 0.000100
Saving checkpoint... 
Iteration: 595533915, states[0] = -61.791941, states[40]= 0.000005
Saving checkpoint... 
Iteration: 609875385, states[0] = -77.549975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623818153, states[0] = 0.453143, states[40]= 0.005997
Saving checkpoint... 
Iteration: 637775641, states[0] = 26.382081, states[40]= 0.091940
Saving checkpoint... 
Iteration: 646639640, states[0] = 8.201122, states[40]= 0.007316
Saving checkpoint... 
Iteration: 660460219, states[0] = 15.456501, states[40]= 0.009127
Saving checkpoint... 
Iteration: 671272775, states[0] = 25.746303, states[40]= 0.085947
Saving checkpoint... 
Iteration: 685289204, states[0] = 16.484548, states[40]= 0.009705
Saving checkpoint... 
Iteration: 699171247, states[0] = -35.071208, states[40]= 0.000282
Saving checkpoint... 
Iteration: 713032382, states[0] = -78.588609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727040779, states[0] = -86.946957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740953369, states[0] = 14.770620, states[40]= 0.008832
Saving checkpoint... 
Iteration: 754911073, states[0] = -87.901297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768831489, states[0] = -35.812264, states[40]= 0.000257
Saving checkpoint... 
Iteration: 782631350, states[0] = 4.153453, states[40]= 0.006676
Saving checkpoint... 
Iteration: 791785350, states[0] = 12.518147, states[40]= 0.008141
Saving checkpoint... 
Iteration: 805402724, states[0] = -87.891101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819403022, states[0] = -87.896365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833290139, states[0] = 6.361092, states[40]= 0.007027
Saving checkpoint... 
Iteration: 847350950, states[0] = -76.419243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 860793073, states[0] = 1.711296, states[40]= 0.006246
Saving checkpoint... 
Iteration: 873350120, states[0] = -79.265466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882756428, states[0] = 22.442841, states[40]= 0.036121
Saving checkpoint... 
Iteration: 896405208, states[0] = -87.924655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910346082, states[0] = -78.743175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924361240, states[0] = -87.676936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938143761, states[0] = -30.132100, states[40]= 0.000489
Saving checkpoint... 
Iteration: 951616165, states[0] = 2.721603, states[40]= 0.006432
Saving checkpoint... 
Iteration: 960425764, states[0] = 17.831711, states[40]= 0.010890
Saving checkpoint... 
Iteration: 974115350, states[0] = 1.463983, states[40]= 0.006199
Saving checkpoint... 
Iteration: 988366806, states[0] = -87.825707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002187008, states[0] = -87.684301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013156959, states[0] = -58.998335, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1027123344, states[0] = -13.981471, states[40]= 0.002206
Saving checkpoint... 
Iteration: 1040764194, states[0] = 10.079388, states[40]= 0.007634
Saving checkpoint... 
Iteration: 1054667173, states[0] = -81.861411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068450315, states[0] = -10.920953, states[40]= 0.002947
Saving checkpoint... 
Iteration: 1082351456, states[0] = -87.787788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096444793, states[0] = -7.387023, states[40]= 0.003947
Saving checkpoint... 
Iteration: 1109704036, states[0] = -87.885897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118858922, states[0] = -87.847728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128231761, states[0] = 22.494730, states[40]= 0.036897
Saving checkpoint... 
Iteration: 1137136317, states[0] = -47.258461, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1150451115, states[0] = -23.515050, states[40]= 0.000898
Saving checkpoint... 
Iteration: 1164163445, states[0] = -86.875961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178195052, states[0] = -87.878803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187349380, states[0] = -87.836700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201364274, states[0] = -87.894381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215103631, states[0] = -12.718666, states[40]= 0.002493
Saving checkpoint... 
Iteration: 1229064850, states[0] = 18.185414, states[40]= 0.011336
Saving checkpoint... 
Iteration: 1242923322, states[0] = 0.062104, states[40]= 0.005914
Saving checkpoint... 
Iteration: 1256944906, states[0] = -29.712477, states[40]= 0.000510
Saving checkpoint... 
Iteration: 1270334418, states[0] = -87.801654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284056074, states[0] = 19.716523, states[40]= 0.014553
Saving checkpoint... 
Iteration: 1297839466, states[0] = -87.841295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306902940, states[0] = 10.949333, states[40]= 0.007798
Saving checkpoint... 
Iteration: 1314401434, states[0] = 11.443590, states[40]= 0.007899
Saving checkpoint... 
Iteration: 1322401377, states[0] = 10.957906, states[40]= 0.007800
Saving checkpoint... 
Iteration: 1336307474, states[0] = -83.860694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349811173, states[0] = -86.773619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363786555, states[0] = -56.066890, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1372954553, states[0] = -59.362426, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1387137104, states[0] = -85.013124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399060999, states[0] = 10.546255, states[40]= 0.007721
Saving checkpoint... 
Iteration: 1412027140, states[0] = 41.381191, states[40]= 0.052021
Saving checkpoint... 
Iteration: 1421108515, states[0] = -48.090194, states[40]= 0.000046
Saving checkpoint... 
Iteration: 1430204103, states[0] = 21.418849, states[40]= 0.024006
Saving checkpoint... 
Iteration: 1443433305, states[0] = -39.391905, states[40]= 0.000162
Saving checkpoint... 
Iteration: 1457396217, states[0] = 4.944037, states[40]= 0.006804
Saving checkpoint... 
Iteration: 1471388712, states[0] = 9.452389, states[40]= 0.007524
Saving checkpoint... 
Iteration: 1485495098, states[0] = -87.869753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499643798, states[0] = -87.793616, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.812979
 - CaMKt in component CaMK (millimolar): 0.037049
 - cass in component intracellular_ions (millimolar): 0.000114
 - nai in component intracellular_ions (millimolar): 6.788329
 - nass in component intracellular_ions (millimolar): 6.788473
 - ki in component intracellular_ions (millimolar): 145.147365
 - kss in component intracellular_ions (millimolar): 145.147333
 - cansr in component intracellular_ions (millimolar): 1.553283
 - cajsr in component intracellular_ions (millimolar): 1.148959
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.007392
 - hf in component INa (dimensionless): 0.695864
 - hs in component INa (dimensionless): 0.695639
 - j in component INa (dimensionless): 0.684326
 - hsp in component INa (dimensionless): 0.451320
 - jp in component INa (dimensionless): 0.656492
 - mL in component INaL (dimensionless): 0.000191
 - hL in component INaL (dimensionless): 0.291477
 - hLp in component INaL (dimensionless): 0.135334
 - a in component Ito (dimensionless): 0.001006
 - iF in component Ito (dimensionless): 0.999548
 - iS in component Ito (dimensionless): 0.174195
 - ap in component Ito (dimensionless): 0.000512
 - iFp in component Ito (dimensionless): 0.999549
 - iSp in component Ito (dimensionless): 0.210275
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.800808
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.965646
 - jca in component ICaL (dimensionless): 0.947127
 - ffp in component ICaL (dimensionless): 0.999852
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.008820
 - xrf in component IKr (dimensionless): 0.030246
 - xrs in component IKr (dimensionless): 0.795291
 - xs1 in component IKs (dimensionless): 0.461641
 - xs2 in component IKs (dimensionless): 0.001246
 - xk1 in component IK1 (dimensionless): 0.996782
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:39:19 (288080): called boinc_finish(0)

</stderr_txt>
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