𝕏

Task 54961474

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_265_1
Workunit 26096718
Created 27 Jun 2024, 17:33:50 UTC
Sent 27 Jun 2024, 18:34:12 UTC
Report deadline 30 Jun 2024, 18:34:12 UTC
Received 30 Jun 2024, 2:37:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214322
Run time 2 hours 32 min 15 sec
CPU time 2 hours 25 min 10 sec
Validate state Valid
Credit 43.20
Device peak FLOPS 2.34 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.13 MB
Peak swap size 5.27 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_265.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_265_1_r581359756_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pieske_333-conf_265_1_r581359756_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.132119
     * GNaL_b in INaL: 0.004533
     * Gto_b in Ito: 0.072234
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033737
     * GKs_b in IKs: 0.001873
     * GK1_b in IK1: 0.170529
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 68.362970
     * GKb_b in IKb: 0.003843
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.024830
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10734044, states[0] = -31.132093, states[40]= 0.000403
Saving checkpoint... 
Iteration: 21565068, states[0] = -29.154458, states[40]= 0.000530
Saving checkpoint... 
Iteration: 32425175, states[0] = -72.614211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43424922, states[0] = -74.364106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54409680, states[0] = -50.972888, states[40]= 0.000031
Saving checkpoint... 
Iteration: 65388398, states[0] = -21.135834, states[40]= 0.001146
Saving checkpoint... 
Iteration: 76347933, states[0] = 17.462429, states[40]= 0.010600
Saving checkpoint... 
Iteration: 87363200, states[0] = 6.492818, states[40]= 0.007301
Saving checkpoint... 
Iteration: 98322060, states[0] = -87.886821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109302460, states[0] = -87.834986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120236077, states[0] = -50.717236, states[40]= 0.000033
Saving checkpoint... 
Iteration: 131091113, states[0] = -85.759852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142091501, states[0] = -86.464914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153097944, states[0] = -87.597416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164077263, states[0] = -70.767868, states[40]= 0.000001
Saving checkpoint... 
Iteration: 175059647, states[0] = -44.367731, states[40]= 0.000084
Saving checkpoint... 
Iteration: 186065347, states[0] = -54.576370, states[40]= 0.000018
Saving checkpoint... 
Iteration: 196877507, states[0] = -24.718859, states[40]= 0.000830
Saving checkpoint... 
Iteration: 207724265, states[0] = -46.171908, states[40]= 0.000064
Saving checkpoint... 
Iteration: 218251027, states[0] = -86.636732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229306736, states[0] = -87.882582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240290740, states[0] = -87.840243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251282691, states[0] = -87.817271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262296575, states[0] = -87.864133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273244322, states[0] = -86.160546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283555879, states[0] = -55.014508, states[40]= 0.000017
Saving checkpoint... 
Iteration: 294486355, states[0] = 20.725870, states[40]= 0.017736
Saving checkpoint... 
Iteration: 305373814, states[0] = -35.353122, states[40]= 0.000279
Saving checkpoint... 
Iteration: 316096260, states[0] = -87.765864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326868818, states[0] = -31.157998, states[40]= 0.000448
Saving checkpoint... 
Iteration: 337729415, states[0] = -76.033947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348756167, states[0] = -87.749116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359698749, states[0] = -30.980184, states[40]= 0.000456
Saving checkpoint... 
Iteration: 370705925, states[0] = -43.157396, states[40]= 0.000099
Saving checkpoint... 
Iteration: 381690375, states[0] = -21.731486, states[40]= 0.001087
Saving checkpoint... 
Iteration: 392659568, states[0] = 11.245526, states[40]= 0.008114
Saving checkpoint... 
Iteration: 403655479, states[0] = 13.248346, states[40]= 0.008574
Saving checkpoint... 
Iteration: 414611023, states[0] = -87.853429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425371057, states[0] = -48.990666, states[40]= 0.000043
Saving checkpoint... 
Iteration: 436300090, states[0] = 23.347194, states[40]= 0.042812
Saving checkpoint... 
Iteration: 447079396, states[0] = -87.747514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457771216, states[0] = -87.846895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468753318, states[0] = -87.789020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479720188, states[0] = -83.561313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490734211, states[0] = -87.682378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501775076, states[0] = -87.870643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511697261, states[0] = -51.250141, states[40]= 0.000030
Saving checkpoint... 
Iteration: 520793931, states[0] = 22.193232, states[40]= 0.028124
Saving checkpoint... 
Iteration: 528653463, states[0] = 5.597666, states[40]= 0.007162
Saving checkpoint... 
Iteration: 533991332, states[0] = 1.074199, states[40]= 0.006348
Saving checkpoint... 
Iteration: 541193750, states[0] = -50.407887, states[40]= 0.000034
Saving checkpoint... 
Iteration: 552063382, states[0] = -87.707821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562859645, states[0] = -52.517221, states[40]= 0.000025
Saving checkpoint... 
Iteration: 573832860, states[0] = -14.232433, states[40]= 0.002243
Saving checkpoint... 
Iteration: 584745690, states[0] = -87.803975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595133571, states[0] = 14.989356, states[40]= 0.009137
Saving checkpoint... 
Iteration: 605657172, states[0] = -6.006431, states[40]= 0.004513
Saving checkpoint... 
Iteration: 616696275, states[0] = -66.491738, states[40]= 0.000003
Saving checkpoint... 
Iteration: 627648849, states[0] = 0.859341, states[40]= 0.006303
Saving checkpoint... 
Iteration: 638636201, states[0] = 10.381105, states[40]= 0.007949
Saving checkpoint... 
Iteration: 649505711, states[0] = -34.838110, states[40]= 0.000296
Saving checkpoint... 
Iteration: 660394584, states[0] = -87.762889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671438521, states[0] = 27.640590, states[40]= 0.101295
Saving checkpoint... 
Iteration: 682417926, states[0] = -87.854232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693384689, states[0] = -87.726128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704363741, states[0] = -82.824076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715372915, states[0] = -87.482187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726365473, states[0] = -86.065472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737240924, states[0] = -87.839327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748169021, states[0] = -44.404053, states[40]= 0.000083
Saving checkpoint... 
Iteration: 759034078, states[0] = -87.382569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770024634, states[0] = -83.715046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780202722, states[0] = -87.625555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790902328, states[0] = -87.839584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801852859, states[0] = -81.327693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812819412, states[0] = -29.958175, states[40]= 0.000507
Saving checkpoint... 
Iteration: 823807570, states[0] = -13.795760, states[40]= 0.002340
Saving checkpoint... 
Iteration: 834803905, states[0] = -10.049741, states[40]= 0.003309
Saving checkpoint... 
Iteration: 845817140, states[0] = -31.483023, states[40]= 0.000433
Saving checkpoint... 
Iteration: 856809009, states[0] = -20.949606, states[40]= 0.001168
Saving checkpoint... 
Iteration: 867745990, states[0] = -87.889641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878532455, states[0] = -87.722916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889372872, states[0] = -87.767825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900359794, states[0] = -87.680009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911345931, states[0] = -85.473445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922327367, states[0] = -58.187628, states[40]= 0.000010
Saving checkpoint... 
Iteration: 933276460, states[0] = 8.134528, states[40]= 0.007567
Saving checkpoint... 
Iteration: 944270934, states[0] = 11.338468, states[40]= 0.008133
Saving checkpoint... 
Iteration: 955173454, states[0] = -84.368132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966144329, states[0] = -40.146672, states[40]= 0.000151
Saving checkpoint... 
Iteration: 977016086, states[0] = -87.616187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988001364, states[0] = -81.957924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998841052, states[0] = -87.018719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009825760, states[0] = -70.306455, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1020806171, states[0] = -41.089373, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1031824886, states[0] = -72.748602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042860545, states[0] = -87.780325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053864066, states[0] = -87.798283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064867775, states[0] = -87.815666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075683008, states[0] = -87.745884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086644737, states[0] = -58.938344, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1097515569, states[0] = -87.753161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108281329, states[0] = -17.122629, states[40]= 0.001686
Saving checkpoint... 
Iteration: 1119079662, states[0] = 15.898203, states[40]= 0.009547
Saving checkpoint... 
Iteration: 1130045734, states[0] = -87.870481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140902961, states[0] = 20.122012, states[40]= 0.015378
Saving checkpoint... 
Iteration: 1151823900, states[0] = -86.486271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162593320, states[0] = 2.776506, states[40]= 0.006679
Saving checkpoint... 
Iteration: 1173525970, states[0] = -87.823754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184287610, states[0] = -37.847292, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1195040786, states[0] = -87.874535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205922273, states[0] = 2.819510, states[40]= 0.006687
Saving checkpoint... 
Iteration: 1216821243, states[0] = -87.339871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1227723899, states[0] = 21.877778, states[40]= 0.025172
Saving checkpoint... 
Iteration: 1238543949, states[0] = 41.248358, states[40]= 0.033806
Saving checkpoint... 
Iteration: 1249496087, states[0] = -87.728048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260369658, states[0] = -87.879882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271226209, states[0] = 18.634945, states[40]= 0.011996
Saving checkpoint... 
Iteration: 1282127865, states[0] = -63.299540, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1293031171, states[0] = -87.874902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303960027, states[0] = -65.020904, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1314920743, states[0] = -7.544783, states[40]= 0.004049
Saving checkpoint... 
Iteration: 1325857315, states[0] = -87.864239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336757578, states[0] = -15.759398, states[40]= 0.001929
Saving checkpoint... 
Iteration: 1347748274, states[0] = -4.331560, states[40]= 0.005005
Saving checkpoint... 
Iteration: 1358738304, states[0] = 4.599916, states[40]= 0.006997
Saving checkpoint... 
Iteration: 1369716120, states[0] = 18.759187, states[40]= 0.012193
Saving checkpoint... 
Iteration: 1380625167, states[0] = -76.122152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1391342455, states[0] = -87.839485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402297464, states[0] = -85.851172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413243971, states[0] = -7.179773, states[40]= 0.004159
Saving checkpoint... 
Iteration: 1424118452, states[0] = -71.760233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435041456, states[0] = 19.507787, states[40]= 0.013659
Saving checkpoint... 
Iteration: 1445672782, states[0] = -87.846887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456455808, states[0] = -83.525848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467448398, states[0] = -73.510202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478307599, states[0] = -87.734810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489214048, states[0] = 12.942870, states[40]= 0.008494
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.765922
 - CaMKt in component CaMK (millimolar): 0.038601
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 7.031215
 - nass in component intracellular_ions (millimolar): 7.031362
 - ki in component intracellular_ions (millimolar): 144.897708
 - kss in component intracellular_ions (millimolar): 144.897675
 - cansr in component intracellular_ions (millimolar): 1.581654
 - cajsr in component intracellular_ions (millimolar): 1.169561
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007427
 - hf in component INa (dimensionless): 0.694225
 - hs in component INa (dimensionless): 0.694005
 - j in component INa (dimensionless): 0.686037
 - hsp in component INa (dimensionless): 0.449539
 - jp in component INa (dimensionless): 0.663786
 - mL in component INaL (dimensionless): 0.000192
 - hL in component INaL (dimensionless): 0.309182
 - hLp in component INaL (dimensionless): 0.146051
 - a in component Ito (dimensionless): 0.001009
 - iF in component Ito (dimensionless): 0.999545
 - iS in component Ito (dimensionless): 0.184171
 - ap in component Ito (dimensionless): 0.000514
 - iFp in component Ito (dimensionless): 0.999545
 - iSp in component Ito (dimensionless): 0.224324
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.810444
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.968625
 - jca in component ICaL (dimensionless): 0.952050
 - ffp in component ICaL (dimensionless): 0.999911
 - fcafp in component ICaL (dimensionless): 0.999994
 - nca in component ICaL (dimensionless): 0.009051
 - xrf in component IKr (dimensionless): 0.024324
 - xrs in component IKr (dimensionless): 0.783977
 - xs1 in component IKs (dimensionless): 0.448092
 - xs2 in component IKs (dimensionless): 0.000901
 - xk1 in component IK1 (dimensionless): 0.996794
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:37:08 (10384): called boinc_finish(0)

</stderr_txt>
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