𝕏

Task 54949871

Name HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254_0
Workunit 26090918
Created 27 Jun 2024, 17:28:14 UTC
Sent 27 Jun 2024, 17:39:28 UTC
Report deadline 1 Jul 2024, 3:15:28 UTC
Received 29 Jun 2024, 18:41:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 190678
Run time 2 hours 24 min 38 sec
CPU time 2 hours 22 min 12 sec
Validate state Valid
Credit 57.95
Device peak FLOPS 3.57 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 5.91 MB
Peak swap size 1.39 MB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>7.6.33</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254_0_r1545768616_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254_0_r1545768616_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.070913
     * GNaL_b in INaL: 0.005662
     * Gto_b in Ito: 0.085191
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032418
     * GKs_b in IKs: 0.001852
     * GK1_b in IK1: 0.155415
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 65.773088
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018539
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14722422, states[0] = -94.853387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29562015, states[0] = 6.277900, states[40]= 0.004787
Saving checkpoint... 
Iteration: 44413293, states[0] = -94.974409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59271286, states[0] = -94.877153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74057465, states[0] = 8.661543, states[40]= 0.004856
Saving checkpoint... 
Iteration: 88849411, states[0] = -94.933671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103656855, states[0] = -82.579574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118356705, states[0] = -94.934389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132875722, states[0] = -94.942438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147716201, states[0] = -94.777967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162576186, states[0] = -0.210903, states[40]= 0.004247
Saving checkpoint... 
Iteration: 177446457, states[0] = -94.963283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192306414, states[0] = -94.899334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207059660, states[0] = 7.881713, states[40]= 0.004834
Saving checkpoint... 
Iteration: 221768758, states[0] = -94.861133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236616667, states[0] = -35.137905, states[40]= 0.000271
Saving checkpoint... 
Iteration: 251482296, states[0] = -94.969535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266320443, states[0] = -94.909904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280617919, states[0] = -36.340062, states[40]= 0.000231
Saving checkpoint... 
Iteration: 295486435, states[0] = -94.970100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310261376, states[0] = -94.851636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325031974, states[0] = 18.221956, states[40]= 0.005526
Saving checkpoint... 
Iteration: 339810693, states[0] = -94.902421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354005303, states[0] = 27.000253, states[40]= 0.151943
Saving checkpoint... 
Iteration: 368839090, states[0] = -94.922112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383631068, states[0] = -49.634297, states[40]= 0.000032
Saving checkpoint... 
Iteration: 398486497, states[0] = -94.970016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413330604, states[0] = -94.916746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428083802, states[0] = -5.161494, states[40]= 0.003387
Saving checkpoint... 
Iteration: 442915145, states[0] = -94.954670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457776074, states[0] = -94.869392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472639018, states[0] = -58.209129, states[40]= 0.000008
Saving checkpoint... 
Iteration: 487511831, states[0] = 22.557723, states[40]= 0.032876
Saving checkpoint... 
Iteration: 502329302, states[0] = -94.915819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517173720, states[0] = -94.481786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531996907, states[0] = -94.971404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546794844, states[0] = -94.888592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561535013, states[0] = 17.245773, states[40]= 0.005304
Saving checkpoint... 
Iteration: 576327337, states[0] = -94.914446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591161931, states[0] = -89.596679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605989606, states[0] = -94.970315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620850964, states[0] = -94.928675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635709849, states[0] = -94.763297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650492428, states[0] = -94.970687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665311836, states[0] = -94.903067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680155808, states[0] = -80.455518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695009232, states[0] = 23.191849, states[40]= 0.061714
Saving checkpoint... 
Iteration: 709877457, states[0] = -94.941191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724749501, states[0] = -94.834760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739610341, states[0] = -29.115091, states[40]= 0.000534
Saving checkpoint... 
Iteration: 754494327, states[0] = -94.970874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769358833, states[0] = -94.932634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783773526, states[0] = -94.866226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798564007, states[0] = 5.981090, states[40]= 0.004769
Saving checkpoint... 
Iteration: 813432865, states[0] = -94.959181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828274460, states[0] = -94.867267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840464109, states[0] = -94.965914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852979466, states[0] = -94.968566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867818015, states[0] = -94.907625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882689230, states[0] = -94.714154, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254_0_r1545768616_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627192118166668_ORdGradInc_k_25-Pueyo_APDR-conf_254_0_r1545768616_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.070913
     * GNaL_b in INaL: 0.005662
     * Gto_b in Ito: 0.085191
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032418
     * GKs_b in IKs: 0.001852
     * GK1_b in IK1: 0.155415
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 65.773088
     * GKb_b in IKb: 0.003828
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.018539
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 882689230
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.714154 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 897417694, states[0] = -94.955056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911624379, states[0] = -42.706654, states[40]= 0.000093
Saving checkpoint... 
Iteration: 924096327, states[0] = -15.907937, states[40]= 0.001364
Saving checkpoint... 
Iteration: 937125652, states[0] = -43.999028, states[40]= 0.000077
Saving checkpoint... 
Iteration: 951969602, states[0] = -94.966824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966808141, states[0] = -94.899870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981680407, states[0] = -94.667886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996528992, states[0] = 19.114462, states[40]= 0.005844
Saving checkpoint... 
Iteration: 1011327775, states[0] = -94.914402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026036903, states[0] = 16.610068, states[40]= 0.005203
Saving checkpoint... 
Iteration: 1040823003, states[0] = -94.911093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055166209, states[0] = -92.937037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069874629, states[0] = -94.939713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084591501, states[0] = -11.470425, states[40]= 0.002063
Saving checkpoint... 
Iteration: 1099359769, states[0] = -94.932841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113394471, states[0] = -94.947449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1126908925, states[0] = -94.952255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140695722, states[0] = -94.730926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155207353, states[0] = -94.757491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169902451, states[0] = -94.950144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184762532, states[0] = -94.852447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199529443, states[0] = 18.984240, states[40]= 0.005787
Saving checkpoint... 
Iteration: 1214375634, states[0] = -94.940030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229132952, states[0] = -51.635143, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1243897755, states[0] = -94.948499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258732217, states[0] = -94.806429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273559640, states[0] = 7.893881, states[40]= 0.004835
Saving checkpoint... 
Iteration: 1288273949, states[0] = -94.866320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303016015, states[0] = 21.949295, states[40]= 0.014386
Saving checkpoint... 
Iteration: 1317834614, states[0] = -94.918614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332686016, states[0] = -94.703000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347484412, states[0] = -94.968959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362339862, states[0] = -94.921799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377195638, states[0] = -94.730537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392035434, states[0] = 17.106095, states[40]= 0.005280
Saving checkpoint... 
Iteration: 1406900582, states[0] = -94.949336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421751497, states[0] = -94.837136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436619971, states[0] = -38.330379, states[40]= 0.000176
Saving checkpoint... 
Iteration: 1451374759, states[0] = -94.939471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466187960, states[0] = -94.709771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481033411, states[0] = 17.768299, states[40]= 0.005411
Saving checkpoint... 
Iteration: 1495838283, states[0] = -94.920743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510567630, states[0] = -2.132803, states[40]= 0.004389
Saving checkpoint... 
Iteration: 1525412206, states[0] = -95.124117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540205674, states[0] = 27.541860, states[40]= 0.128737
Saving checkpoint... 
Iteration: 1554905112, states[0] = 28.679417, states[40]= 0.139891
Saving checkpoint... 
Iteration: 1569745636, states[0] = -94.172873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584510420, states[0] = -95.151015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599334149, states[0] = 15.485977, states[40]= 0.006322
Saving checkpoint... 
Iteration: 1614164745, states[0] = -95.040815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1629020888, states[0] = 20.568303, states[40]= 0.009502
Saving checkpoint... 
Iteration: 1643841643, states[0] = -92.741925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658583345, states[0] = -95.096175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673313161, states[0] = -95.161582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688127979, states[0] = 18.042037, states[40]= 0.007045
Saving checkpoint... 
Iteration: 1702955035, states[0] = -94.976141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717784331, states[0] = -95.252849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732604007, states[0] = -42.429836, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1747404345, states[0] = -95.144676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762103255, states[0] = -95.142436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776926954, states[0] = 18.437932, states[40]= 0.007233
Saving checkpoint... 
Iteration: 1791730942, states[0] = -77.779988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806566884, states[0] = 3.250396, states[40]= 0.004713
Saving checkpoint... 
Iteration: 1821371322, states[0] = -94.978234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836209938, states[0] = -94.789718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1851030457, states[0] = 18.491840, states[40]= 0.005650
Saving checkpoint... 
Iteration: 1865836551, states[0] = -94.930854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880674766, states[0] = -94.563673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895475177, states[0] = -94.971862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910118959, states[0] = -37.526759, states[40]= 0.000197
Saving checkpoint... 
Iteration: 1924910594, states[0] = -94.954174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939732233, states[0] = -94.807249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954546606, states[0] = 13.083825, states[40]= 0.004941
Saving checkpoint... 
Iteration: 1969318576, states[0] = -94.907695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983728782, states[0] = -94.800047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998513971, states[0] = 22.236417, states[40]= 0.020739
Saving checkpoint... 
Iteration: 2013315618, states[0] = -94.905028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028127572, states[0] = -45.978775, states[40]= 0.000057
Saving checkpoint... 
Iteration: 2042936450, states[0] = -94.959099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057718878, states[0] = -94.780803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072560919, states[0] = 7.344834, states[40]= 0.004819
Saving checkpoint... 
Iteration: 2087253838, states[0] = -94.839913, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.846414
 - CaMKt in component CaMK (millimolar): 0.007391
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.711375
 - nass in component intracellular_ions (millimolar): 6.711438
 - ki in component intracellular_ions (millimolar): 145.258470
 - kss in component intracellular_ions (millimolar): 145.258451
 - cansr in component intracellular_ions (millimolar): 1.340979
 - cajsr in component intracellular_ions (millimolar): 1.302574
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003639
 - hf in component INa (dimensionless): 0.879036
 - hs in component INa (dimensionless): 0.879030
 - j in component INa (dimensionless): 0.878997
 - hsp in component INa (dimensionless): 0.724010
 - jp in component INa (dimensionless): 0.878975
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708105
 - hLp in component INaL (dimensionless): 0.449338
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.620191
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.694832
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935033
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001716
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326066
 - xs1 in component IKs (dimensionless): 0.241932
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997352
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:40:26 (812): called boinc_finish(0)

</stderr_txt>
]]>