𝕏

Task 54933629

Name HuVeMOp_20240627033051610017_ORdGradInc_k_24-Pueyo_APDR-conf_853_2
Workunit 26078283
Created 27 Jun 2024, 16:12:14 UTC
Sent 27 Jun 2024, 16:12:26 UTC
Report deadline 1 Jul 2024, 1:48:26 UTC
Received 30 Jun 2024, 16:54:32 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 14 min 56 sec
CPU time 2 hours 14 min 15 sec
Validate state Valid
Credit 66.76
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627033051610017_ORdGradInc_k_24-Pueyo_APDR-conf_853.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627033051610017_ORdGradInc_k_24-Pueyo_APDR-conf_853_2_r2004852609_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627033051610017_ORdGradInc_k_24-Pueyo_APDR-conf_853_2_r2004852609_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.642787
     * GNaL_b in INaL: 0.005502
     * Gto_b in Ito: 0.066779
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034048
     * GKs_b in IKs: 0.001822
     * GK1_b in IK1: 0.162950
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.454078
     * GKb_b in IKb: 0.003767
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052246
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11942054, states[0] = -95.307504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24064516, states[0] = 1.726948, states[40]= 0.004676
Saving checkpoint... 
Iteration: 35948407, states[0] = -95.253792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48043382, states[0] = 12.845336, states[40]= 0.005598
Saving checkpoint... 
Iteration: 60119345, states[0] = -50.072461, states[40]= 0.000024
Saving checkpoint... 
Iteration: 72157982, states[0] = -94.788160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84343753, states[0] = -95.191414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96358068, states[0] = -95.193776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108474666, states[0] = -95.217335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120489586, states[0] = -95.217450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132348001, states[0] = -95.184925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144498720, states[0] = -95.216442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156484536, states[0] = -95.214378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168210391, states[0] = -95.065265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180105827, states[0] = -33.157396, states[40]= 0.000290
Saving checkpoint... 
Iteration: 191910352, states[0] = -95.201487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204069955, states[0] = 0.422978, states[40]= 0.004461
Saving checkpoint... 
Iteration: 216090920, states[0] = -17.307504, states[40]= 0.001211
Saving checkpoint... 
Iteration: 227982897, states[0] = -95.212935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240078217, states[0] = -5.250776, states[40]= 0.003454
Saving checkpoint... 
Iteration: 252004000, states[0] = 35.535880, states[40]= 0.118573
Saving checkpoint... 
Iteration: 264066265, states[0] = 2.549358, states[40]= 0.004714
Saving checkpoint... 
Iteration: 276138812, states[0] = -73.971853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288072332, states[0] = -1.044720, states[40]= 0.004246
Saving checkpoint... 
Iteration: 300340324, states[0] = -95.178881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312424114, states[0] = -95.203816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324562820, states[0] = 4.379738, states[40]= 0.004884
Saving checkpoint... 
Iteration: 336638522, states[0] = -73.491218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348499345, states[0] = -95.214436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360748903, states[0] = -95.114807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372694817, states[0] = -95.037764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384633907, states[0] = -66.535480, states[40]= 0.000001
Saving checkpoint... 
Iteration: 396838815, states[0] = -95.178161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408856883, states[0] = -95.185408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420773399, states[0] = -95.138049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432801036, states[0] = -95.158189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444707022, states[0] = -95.058692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456405338, states[0] = -95.199706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468479821, states[0] = -95.212287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480319134, states[0] = -95.168647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492411495, states[0] = -95.201089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504141059, states[0] = -77.816303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516229382, states[0] = -95.091499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528263622, states[0] = -95.129408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540269180, states[0] = -95.134393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551625798, states[0] = -56.023588, states[40]= 0.000009
Saving checkpoint... 
Iteration: 563708362, states[0] = -95.060810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575683504, states[0] = -95.016426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587447115, states[0] = -95.207752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599501834, states[0] = 48.516140, states[40]= 0.059221
Saving checkpoint... 
Iteration: 611425681, states[0] = -95.203974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623495939, states[0] = -95.213972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635554898, states[0] = 8.241118, states[40]= 0.005157
Saving checkpoint... 
Iteration: 647456508, states[0] = -95.209156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659475672, states[0] = -95.211708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671955801, states[0] = -95.209042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683965158, states[0] = -95.210351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696570116, states[0] = 0.338126, states[40]= 0.004449
Saving checkpoint... 
Iteration: 708465338, states[0] = -95.210364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720375984, states[0] = -95.191701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732522200, states[0] = 21.480420, states[40]= 0.009782
Saving checkpoint... 
Iteration: 744482675, states[0] = -95.212497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756303994, states[0] = -95.159891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768113289, states[0] = -41.263461, states[40]= 0.000095
Saving checkpoint... 
Iteration: 780004303, states[0] = 34.347749, states[40]= 0.120695
Saving checkpoint... 
Iteration: 792078075, states[0] = -5.132372, states[40]= 0.003479
Saving checkpoint... 
Iteration: 804043053, states[0] = 13.526547, states[40]= 0.005610
Saving checkpoint... 
Iteration: 815880510, states[0] = -95.193021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827999593, states[0] = -95.214245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839765173, states[0] = -95.130694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851632906, states[0] = -65.151113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 863653779, states[0] = -93.888941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875653852, states[0] = -93.912734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887755835, states[0] = -95.121763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900232030, states[0] = -95.094762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911535063, states[0] = 16.848137, states[40]= 0.006260
Saving checkpoint... 
Iteration: 923625129, states[0] = -55.201924, states[40]= 0.000010
Saving checkpoint... 
Iteration: 935727666, states[0] = -95.089043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947644754, states[0] = -84.500115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959804289, states[0] = -95.159983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971723302, states[0] = -95.083068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983747598, states[0] = -95.113118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995908916, states[0] = -95.200294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007709370, states[0] = -95.062231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019737951, states[0] = -95.102053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031685529, states[0] = -95.020156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043560961, states[0] = 5.322512, states[40]= 0.004958
Saving checkpoint... 
Iteration: 1055691010, states[0] = -95.030500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067764756, states[0] = -95.130214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079688428, states[0] = -95.025661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091486717, states[0] = -95.212799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103335806, states[0] = -95.176517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115338286, states[0] = -95.177615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127276175, states[0] = -95.140027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139104056, states[0] = -31.207846, states[40]= 0.000364
Saving checkpoint... 
Iteration: 1151099000, states[0] = -25.824939, states[40]= 0.000608
Saving checkpoint... 
Iteration: 1162905933, states[0] = -95.199537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174796415, states[0] = -95.154874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186906573, states[0] = -95.199675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198784775, states[0] = -95.146686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210673612, states[0] = -94.994883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222820290, states[0] = -95.168932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234626915, states[0] = -57.404150, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1246671600, states[0] = -94.989140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258573758, states[0] = -1.983906, states[40]= 0.004090
Saving checkpoint... 
Iteration: 1270427510, states[0] = -95.204039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282527192, states[0] = 19.811790, states[40]= 0.007675
Saving checkpoint... 
Iteration: 1294570571, states[0] = 0.061890, states[40]= 0.004411
Saving checkpoint... 
Iteration: 1306443732, states[0] = -95.206893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318566336, states[0] = 2.512523, states[40]= 0.004710
Saving checkpoint... 
Iteration: 1330481500, states[0] = -95.212107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342211651, states[0] = -95.065686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354268365, states[0] = -95.133324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365882862, states[0] = -95.193466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377801758, states[0] = -95.158231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389936412, states[0] = -95.205615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401821382, states[0] = -95.169422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413823130, states[0] = -95.170314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425816080, states[0] = -95.166595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437403716, states[0] = -95.198897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449573589, states[0] = -1.870053, states[40]= 0.004110
Saving checkpoint... 
Iteration: 1461248162, states[0] = -95.113522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473261728, states[0] = -95.127229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485347931, states[0] = -95.181501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496957352, states[0] = -95.208909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508985207, states[0] = -95.435508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521029726, states[0] = 17.738904, states[40]= 0.008034
Saving checkpoint... 
Iteration: 1532831154, states[0] = -91.525102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544886912, states[0] = -95.358048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1557005166, states[0] = 32.766022, states[40]= 0.100661
Saving checkpoint... 
Iteration: 1568999676, states[0] = -95.485514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581051184, states[0] = 5.537350, states[40]= 0.005647
Saving checkpoint... 
Iteration: 1592950234, states[0] = -95.455264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1604965938, states[0] = -95.469612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616838616, states[0] = -95.043114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628662115, states[0] = -95.468083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1640603383, states[0] = -95.402980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652516156, states[0] = -68.640247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1664450537, states[0] = 5.821941, states[40]= 0.005688
Saving checkpoint... 
Iteration: 1676517082, states[0] = -70.168912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1688255374, states[0] = -95.307847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700428980, states[0] = 17.603476, states[40]= 0.008184
Saving checkpoint... 
Iteration: 1712547239, states[0] = -95.275819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724390844, states[0] = -95.488989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1736531959, states[0] = -93.435070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748402314, states[0] = 45.717964, states[40]= 0.061627
Saving checkpoint... 
Iteration: 1760457170, states[0] = 1.440558, states[40]= 0.005139
Saving checkpoint... 
Iteration: 1772638847, states[0] = -95.448258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784142891, states[0] = 10.327426, states[40]= 0.006247
Saving checkpoint... 
Iteration: 1795844939, states[0] = 9.158394, states[40]= 0.006086
Saving checkpoint... 
Iteration: 1808001976, states[0] = 47.201795, states[40]= 0.077468
Saving checkpoint... 
Iteration: 1819831788, states[0] = -95.212690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831925504, states[0] = -95.230906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843848478, states[0] = -95.201172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855507212, states[0] = 27.837196, states[40]= 0.091971
Saving checkpoint... 
Iteration: 1867575904, states[0] = -3.899053, states[40]= 0.003743
Saving checkpoint... 
Iteration: 1879384725, states[0] = -95.200843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891377998, states[0] = -95.196819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903450606, states[0] = -95.211271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915315330, states[0] = -95.168510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927423499, states[0] = -95.204756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939096507, states[0] = -23.270980, states[40]= 0.000741
Saving checkpoint... 
Iteration: 1950905263, states[0] = -95.199938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962935595, states[0] = -95.205852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1974648295, states[0] = -89.982397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986734463, states[0] = -95.097670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998923346, states[0] = -95.203118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010735687, states[0] = -95.099004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022768325, states[0] = -95.133085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034579295, states[0] = -6.118533, states[40]= 0.003266
Saving checkpoint... 
Iteration: 2046542613, states[0] = 13.714387, states[40]= 0.005635
Saving checkpoint... 
Iteration: 2058280669, states[0] = -95.143199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069571098, states[0] = -0.263658, states[40]= 0.004364
Saving checkpoint... 
Iteration: 2081552613, states[0] = 9.295157, states[40]= 0.005226
Saving checkpoint... 
Iteration: 2093533907, states[0] = 17.305777, states[40]= 0.006401
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.089585
 - CaMKt in component CaMK (millimolar): 0.006151
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.484242
 - nass in component intracellular_ions (millimolar): 6.484300
 - ki in component intracellular_ions (millimolar): 145.504749
 - kss in component intracellular_ions (millimolar): 145.504729
 - cansr in component intracellular_ions (millimolar): 1.268209
 - cajsr in component intracellular_ions (millimolar): 1.232112
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003551
 - hf in component INa (dimensionless): 0.883220
 - hs in component INa (dimensionless): 0.883216
 - j in component INa (dimensionless): 0.883193
 - hsp in component INa (dimensionless): 0.731930
 - jp in component INa (dimensionless): 0.883177
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.717511
 - hLp in component INaL (dimensionless): 0.465905
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.633451
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.710303
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938702
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001452
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331598
 - xs1 in component IKs (dimensionless): 0.228386
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997287
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:54:17 (158944): called boinc_finish(0)

</stderr_txt>
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