𝕏

Task 54933625

Name HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_985_2
Workunit 26078026
Created 27 Jun 2024, 16:12:14 UTC
Sent 27 Jun 2024, 16:12:26 UTC
Report deadline 1 Jul 2024, 1:48:26 UTC
Received 30 Jun 2024, 18:18:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 14 min 30 sec
CPU time 2 hours 13 min 45 sec
Validate state Valid
Credit 65.32
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.75 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_985.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_985_2_r683284533_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_985_2_r683284533_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.714014
     * GNaL_b in INaL: 0.008742
     * Gto_b in Ito: 0.081126
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033372
     * GKs_b in IKs: 0.001859
     * GK1_b in IK1: 0.156928
     * Gncx_b in INaCa_i: 0.000951
     * Pnak_b in INaK: 62.882422
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052132
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11673932, states[0] = -94.551454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23793846, states[0] = -94.975723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35720496, states[0] = -94.876851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47872986, states[0] = -95.007050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59974874, states[0] = -95.028361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71572761, states[0] = 4.126674, states[40]= 0.004631
Saving checkpoint... 
Iteration: 83755184, states[0] = -94.915061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95798522, states[0] = -94.957145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107686887, states[0] = -94.787536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119536769, states[0] = 18.318711, states[40]= 0.005273
Saving checkpoint... 
Iteration: 131253702, states[0] = -94.910259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143431115, states[0] = -95.013501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155706515, states[0] = -94.834987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167606877, states[0] = -20.529105, states[40]= 0.000957
Saving checkpoint... 
Iteration: 179844828, states[0] = -94.983873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191998706, states[0] = -95.023761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203882190, states[0] = -94.999329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215953054, states[0] = -95.017137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228018997, states[0] = 22.861268, states[40]= 0.010136
Saving checkpoint... 
Iteration: 240174445, states[0] = -94.296891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252306610, states[0] = -94.960448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263943194, states[0] = -95.015212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275866968, states[0] = -94.993487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288032452, states[0] = 19.684361, states[40]= 0.005588
Saving checkpoint... 
Iteration: 299955784, states[0] = -95.017473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312084160, states[0] = -1.920249, states[40]= 0.003936
Saving checkpoint... 
Iteration: 324154755, states[0] = -72.118992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336121101, states[0] = -33.635228, states[40]= 0.000340
Saving checkpoint... 
Iteration: 348271030, states[0] = -94.929039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360276826, states[0] = -94.934944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372322008, states[0] = -94.970737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384510884, states[0] = 24.001030, states[40]= 0.041164
Saving checkpoint... 
Iteration: 396186770, states[0] = -94.784342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408343198, states[0] = -94.982645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420492147, states[0] = -95.022658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432343487, states[0] = -94.982775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444650618, states[0] = -66.317422, states[40]= 0.000002
Saving checkpoint... 
Iteration: 456798069, states[0] = -94.953765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468650283, states[0] = -65.876227, states[40]= 0.000002
Saving checkpoint... 
Iteration: 480776866, states[0] = -94.934899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492614389, states[0] = -27.390907, states[40]= 0.000642
Saving checkpoint... 
Iteration: 504337414, states[0] = -94.979567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516505305, states[0] = 28.125627, states[40]= 0.143750
Saving checkpoint... 
Iteration: 528522242, states[0] = 22.273851, states[40]= 0.007804
Saving checkpoint... 
Iteration: 540518281, states[0] = 22.974590, states[40]= 0.010955
Saving checkpoint... 
Iteration: 552609865, states[0] = -23.243751, states[40]= 0.000828
Saving checkpoint... 
Iteration: 564647146, states[0] = -61.891998, states[40]= 0.000004
Saving checkpoint... 
Iteration: 576976214, states[0] = -95.020465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589130545, states[0] = -42.955775, states[40]= 0.000093
Saving checkpoint... 
Iteration: 600692264, states[0] = -94.804237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612868071, states[0] = -94.993680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624962456, states[0] = -95.018353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637018384, states[0] = 22.958763, states[40]= 0.010828
Saving checkpoint... 
Iteration: 649186536, states[0] = -94.782871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661063435, states[0] = 8.421812, states[40]= 0.004828
Saving checkpoint... 
Iteration: 673211962, states[0] = -94.844336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685352005, states[0] = -94.986726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697209552, states[0] = -94.839849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709107266, states[0] = -20.865996, states[40]= 0.000939
Saving checkpoint... 
Iteration: 721208835, states[0] = -94.838488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733173146, states[0] = -94.069001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745366447, states[0] = -94.992939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757028473, states[0] = 20.810046, states[40]= 0.006072
Saving checkpoint... 
Iteration: 769313181, states[0] = -94.964698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781485230, states[0] = -95.021545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793100665, states[0] = -14.834983, states[40]= 0.001478
Saving checkpoint... 
Iteration: 805188937, states[0] = -94.793788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817278465, states[0] = -94.936237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829278515, states[0] = -94.936278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841506522, states[0] = 26.226191, states[40]= 0.114552
Saving checkpoint... 
Iteration: 853397704, states[0] = -95.003753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865589471, states[0] = -5.502940, states[40]= 0.003263
Saving checkpoint... 
Iteration: 877778262, states[0] = -94.935998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889606258, states[0] = -19.943021, states[40]= 0.000991
Saving checkpoint... 
Iteration: 901451674, states[0] = -95.016332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913584994, states[0] = -2.445586, states[40]= 0.003849
Saving checkpoint... 
Iteration: 925311936, states[0] = -94.963736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937544880, states[0] = 15.560219, states[40]= 0.004989
Saving checkpoint... 
Iteration: 949253092, states[0] = -94.907912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961561967, states[0] = 9.031627, states[40]= 0.004843
Saving checkpoint... 
Iteration: 973507915, states[0] = 25.042809, states[40]= 0.083628
Saving checkpoint... 
Iteration: 985148851, states[0] = -64.026936, states[40]= 0.000003
Saving checkpoint... 
Iteration: 996990968, states[0] = -95.022120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008940121, states[0] = -95.014075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020932015, states[0] = -95.012385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032908218, states[0] = -95.006620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044838786, states[0] = -94.979926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056990913, states[0] = -95.022072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069439259, states[0] = -95.013861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081256404, states[0] = -94.911938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093506101, states[0] = 26.763228, states[40]= 0.124831
Saving checkpoint... 
Iteration: 1105594795, states[0] = -9.686324, states[40]= 0.002375
Saving checkpoint... 
Iteration: 1117561283, states[0] = 9.312332, states[40]= 0.004850
Saving checkpoint... 
Iteration: 1129902139, states[0] = -95.004861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141554084, states[0] = 12.154135, states[40]= 0.004896
Saving checkpoint... 
Iteration: 1153647421, states[0] = -62.231708, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1165800273, states[0] = -94.955013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177742313, states[0] = -94.893358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189847444, states[0] = -94.984214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201880045, states[0] = -94.997767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213623463, states[0] = -35.883023, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1225807455, states[0] = -94.960361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237475610, states[0] = -95.019927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249556428, states[0] = 11.249161, states[40]= 0.004884
Saving checkpoint... 
Iteration: 1261378401, states[0] = -94.997140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273528220, states[0] = 20.877196, states[40]= 0.006112
Saving checkpoint... 
Iteration: 1285649971, states[0] = -65.467586, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1297653152, states[0] = -69.783153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1309773767, states[0] = -94.931213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322085632, states[0] = -2.856396, states[40]= 0.003777
Saving checkpoint... 
Iteration: 1334072777, states[0] = 4.249868, states[40]= 0.004634
Saving checkpoint... 
Iteration: 1345898941, states[0] = -95.003783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358048598, states[0] = 14.211568, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1370071023, states[0] = 5.078483, states[40]= 0.004686
Saving checkpoint... 
Iteration: 1382285229, states[0] = -94.942209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394121294, states[0] = -33.816924, states[40]= 0.000332
Saving checkpoint... 
Iteration: 1406014855, states[0] = 23.441654, states[40]= 0.018017
Saving checkpoint... 
Iteration: 1418115203, states[0] = -28.140248, states[40]= 0.000604
Saving checkpoint... 
Iteration: 1430373173, states[0] = -94.995097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442342122, states[0] = -94.981389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454447282, states[0] = -95.015152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466403059, states[0] = -95.004893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478129941, states[0] = -42.326841, states[40]= 0.000103
Saving checkpoint... 
Iteration: 1490196665, states[0] = -94.813901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502179115, states[0] = -7.625616, states[40]= 0.003063
Saving checkpoint... 
Iteration: 1514120315, states[0] = 22.370117, states[40]= 0.010515
Saving checkpoint... 
Iteration: 1526175486, states[0] = -6.116192, states[40]= 0.003548
Saving checkpoint... 
Iteration: 1538117391, states[0] = 22.936101, states[40]= 0.013699
Saving checkpoint... 
Iteration: 1549822669, states[0] = 21.350259, states[40]= 0.008801
Saving checkpoint... 
Iteration: 1561889250, states[0] = -20.896419, states[40]= 0.000999
Saving checkpoint... 
Iteration: 1573790484, states[0] = -95.302950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585836978, states[0] = 15.630548, states[40]= 0.006201
Saving checkpoint... 
Iteration: 1597621767, states[0] = -58.361362, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1609539035, states[0] = 14.660237, states[40]= 0.006076
Saving checkpoint... 
Iteration: 1621554588, states[0] = 6.912213, states[40]= 0.005507
Saving checkpoint... 
Iteration: 1633665265, states[0] = -95.116077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645211485, states[0] = 24.225974, states[40]= 0.036974
Saving checkpoint... 
Iteration: 1657271750, states[0] = -4.203781, states[40]= 0.004023
Saving checkpoint... 
Iteration: 1669348540, states[0] = -94.325422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681298951, states[0] = -31.638828, states[40]= 0.000423
Saving checkpoint... 
Iteration: 1693360071, states[0] = -95.086899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705180362, states[0] = -95.303371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717299826, states[0] = -32.574503, states[40]= 0.000381
Saving checkpoint... 
Iteration: 1729361763, states[0] = -95.099943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741165719, states[0] = -95.290929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753243485, states[0] = 12.531855, states[40]= 0.005871
Saving checkpoint... 
Iteration: 1765381244, states[0] = -95.161182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777265621, states[0] = 0.295391, states[40]= 0.004861
Saving checkpoint... 
Iteration: 1789337646, states[0] = -83.574866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801442027, states[0] = -95.085128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813246699, states[0] = -94.946788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825035250, states[0] = 18.353965, states[40]= 0.005342
Saving checkpoint... 
Iteration: 1837048779, states[0] = 13.726829, states[40]= 0.004947
Saving checkpoint... 
Iteration: 1848891225, states[0] = -95.019926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860712299, states[0] = -94.857632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872668482, states[0] = -92.572514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884405270, states[0] = -95.011975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896220369, states[0] = -94.863331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908228271, states[0] = -94.875081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920197267, states[0] = -94.817266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931998965, states[0] = -95.024099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943855753, states[0] = -94.988747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955707516, states[0] = -94.835967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967771625, states[0] = -94.929110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979737521, states[0] = -94.886272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991830208, states[0] = -94.974788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003915169, states[0] = -95.007924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015786542, states[0] = -94.943045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027887582, states[0] = -94.999813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039820334, states[0] = -94.968544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051886602, states[0] = -94.999415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063969482, states[0] = -95.018430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075928936, states[0] = -95.010942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087973086, states[0] = -95.018927, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898238
 - CaMKt in component CaMK (millimolar): 0.007253
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.811336
 - nass in component intracellular_ions (millimolar): 6.811396
 - ki in component intracellular_ions (millimolar): 145.163209
 - kss in component intracellular_ions (millimolar): 145.163188
 - cansr in component intracellular_ions (millimolar): 1.323672
 - cajsr in component intracellular_ions (millimolar): 1.284846
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879938
 - hs in component INa (dimensionless): 0.879934
 - j in component INa (dimensionless): 0.879905
 - hsp in component INa (dimensionless): 0.725713
 - jp in component INa (dimensionless): 0.879887
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708563
 - hLp in component INaL (dimensionless): 0.448161
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.615022
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.688280
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927610
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999862
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001643
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339790
 - xs1 in component IKs (dimensionless): 0.255603
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:18:17 (159096): called boinc_finish(0)

</stderr_txt>
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