𝕏

Task 54933624

Name HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_385_2
Workunit 26078025
Created 27 Jun 2024, 16:12:14 UTC
Sent 27 Jun 2024, 16:12:26 UTC
Report deadline 1 Jul 2024, 1:48:26 UTC
Received 30 Jun 2024, 18:11:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 15 min 23 sec
CPU time 2 hours 14 min 37 sec
Validate state Valid
Credit 65.79
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_385.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_385_2_r778908275_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_385_2_r778908275_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 114.888425
     * GNaL_b in INaL: 0.006832
     * Gto_b in Ito: 0.092991
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032225
     * GKs_b in IKs: 0.001814
     * GK1_b in IK1: 0.156998
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 66.729359
     * GKb_b in IKb: 0.003983
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052262
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12145859, states[0] = -70.042256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23989525, states[0] = -95.129571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35865315, states[0] = -95.085660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48015667, states[0] = 21.335523, states[40]= 0.016346
Saving checkpoint... 
Iteration: 59902698, states[0] = -95.082757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72119072, states[0] = -36.118522, states[40]= 0.000229
Saving checkpoint... 
Iteration: 84050195, states[0] = 11.710838, states[40]= 0.004867
Saving checkpoint... 
Iteration: 95760866, states[0] = -94.985785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107911335, states[0] = -95.074154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119679816, states[0] = -94.808987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131942704, states[0] = -95.079505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144018600, states[0] = 21.074891, states[40]= 0.010922
Saving checkpoint... 
Iteration: 155744589, states[0] = -94.960867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167880183, states[0] = -95.061633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179919536, states[0] = -95.073063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191957830, states[0] = -95.080766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204031360, states[0] = 18.199791, states[40]= 0.005721
Saving checkpoint... 
Iteration: 216007336, states[0] = 23.723218, states[40]= 0.101254
Saving checkpoint... 
Iteration: 228072910, states[0] = 2.219147, states[40]= 0.004432
Saving checkpoint... 
Iteration: 240149638, states[0] = -69.393511, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251927883, states[0] = -95.074584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263968836, states[0] = -95.082221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276031222, states[0] = 18.241804, states[40]= 0.005737
Saving checkpoint... 
Iteration: 287947601, states[0] = -95.078582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299956303, states[0] = -95.080133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311648797, states[0] = -68.247517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 323531516, states[0] = 18.157255, states[40]= 0.005704
Saving checkpoint... 
Iteration: 335638842, states[0] = -56.230360, states[40]= 0.000010
Saving checkpoint... 
Iteration: 347452228, states[0] = -95.079374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359522667, states[0] = 20.361052, states[40]= 0.007750
Saving checkpoint... 
Iteration: 371690747, states[0] = -94.862987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383472145, states[0] = -95.082603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395545889, states[0] = 13.400563, states[40]= 0.004931
Saving checkpoint... 
Iteration: 407600450, states[0] = -18.125438, states[40]= 0.001106
Saving checkpoint... 
Iteration: 419550923, states[0] = 11.555448, states[40]= 0.004856
Saving checkpoint... 
Iteration: 431486939, states[0] = -95.084618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443013179, states[0] = 21.799229, states[40]= 0.026290
Saving checkpoint... 
Iteration: 455046696, states[0] = 13.109343, states[40]= 0.004915
Saving checkpoint... 
Iteration: 466810780, states[0] = -95.025772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478861293, states[0] = -95.053470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490986092, states[0] = -95.084469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503236435, states[0] = -94.948021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514993772, states[0] = -95.085414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527021503, states[0] = 20.588773, states[40]= 0.008371
Saving checkpoint... 
Iteration: 538799633, states[0] = -95.017496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550419814, states[0] = -95.072440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562588797, states[0] = -7.829569, states[40]= 0.002754
Saving checkpoint... 
Iteration: 574480014, states[0] = -95.083600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586431811, states[0] = -95.075176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598570687, states[0] = 3.316466, states[40]= 0.004526
Saving checkpoint... 
Iteration: 610508606, states[0] = 22.886111, states[40]= 0.075456
Saving checkpoint... 
Iteration: 622583022, states[0] = -3.606399, states[40]= 0.003617
Saving checkpoint... 
Iteration: 634603785, states[0] = -21.217802, states[40]= 0.000894
Saving checkpoint... 
Iteration: 646432468, states[0] = -95.075278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658521956, states[0] = 20.502114, states[40]= 0.008110
Saving checkpoint... 
Iteration: 670623599, states[0] = -39.932267, states[40]= 0.000134
Saving checkpoint... 
Iteration: 682470475, states[0] = -95.082153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694469131, states[0] = -95.081941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706336423, states[0] = -95.041388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718178859, states[0] = -94.789518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730098146, states[0] = -15.994864, states[40]= 0.001323
Saving checkpoint... 
Iteration: 742112975, states[0] = -29.754462, states[40]= 0.000489
Saving checkpoint... 
Iteration: 753927935, states[0] = -95.074207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765833944, states[0] = -95.039993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777963928, states[0] = -95.081071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789971462, states[0] = -95.082230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801836326, states[0] = -95.041272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813687920, states[0] = -94.854907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825589998, states[0] = -8.801199, states[40]= 0.002549
Saving checkpoint... 
Iteration: 837574283, states[0] = 1.519248, states[40]= 0.004363
Saving checkpoint... 
Iteration: 849642289, states[0] = -60.182695, states[40]= 0.000005
Saving checkpoint... 
Iteration: 861688317, states[0] = -94.856072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873593308, states[0] = -11.621007, states[40]= 0.001989
Saving checkpoint... 
Iteration: 885686969, states[0] = -94.851793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897486479, states[0] = -95.084249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909636053, states[0] = -53.107975, states[40]= 0.000017
Saving checkpoint... 
Iteration: 921706137, states[0] = -94.895382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933394626, states[0] = -95.065270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945141117, states[0] = -58.823351, states[40]= 0.000007
Saving checkpoint... 
Iteration: 956741997, states[0] = -94.955804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968822464, states[0] = -95.033126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980659009, states[0] = -84.234346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992451201, states[0] = -95.078758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004531782, states[0] = 18.080167, states[40]= 0.005675
Saving checkpoint... 
Iteration: 1016623543, states[0] = -39.876372, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1028463505, states[0] = -95.080837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040516183, states[0] = 21.426003, states[40]= 0.015140
Saving checkpoint... 
Iteration: 1052566067, states[0] = 5.447660, states[40]= 0.004662
Saving checkpoint... 
Iteration: 1064599928, states[0] = -17.641411, states[40]= 0.001150
Saving checkpoint... 
Iteration: 1076866966, states[0] = -95.055414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088745030, states[0] = -94.959937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100829208, states[0] = -95.037086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113013031, states[0] = 21.818546, states[40]= 0.027118
Saving checkpoint... 
Iteration: 1124589480, states[0] = -8.378229, states[40]= 0.002638
Saving checkpoint... 
Iteration: 1136671264, states[0] = -94.329482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148341236, states[0] = -95.043635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160339156, states[0] = -95.042544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172681231, states[0] = -94.819629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184498921, states[0] = -95.085576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196575694, states[0] = 0.772869, states[40]= 0.004281
Saving checkpoint... 
Iteration: 1208611276, states[0] = -28.168040, states[40]= 0.000566
Saving checkpoint... 
Iteration: 1220484939, states[0] = -95.083834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232257465, states[0] = -94.975837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244037672, states[0] = 16.245566, states[40]= 0.005217
Saving checkpoint... 
Iteration: 1256035764, states[0] = 16.863288, states[40]= 0.005333
Saving checkpoint... 
Iteration: 1267988071, states[0] = -95.084208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279848491, states[0] = -95.047157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291906885, states[0] = -95.068604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303962609, states[0] = -95.080509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315945030, states[0] = -95.077393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328069383, states[0] = 3.936220, states[40]= 0.004571
Saving checkpoint... 
Iteration: 1339931212, states[0] = -95.074545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352191038, states[0] = -94.863053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363709771, states[0] = -94.902111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375290346, states[0] = -95.009336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387359808, states[0] = -95.052232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399419534, states[0] = -95.071809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411130781, states[0] = -47.352885, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1423221323, states[0] = -94.923071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435065250, states[0] = 5.807626, states[40]= 0.004680
Saving checkpoint... 
Iteration: 1446827741, states[0] = -95.035998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458897116, states[0] = -95.065681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470544275, states[0] = 13.978177, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1482547764, states[0] = 12.721507, states[40]= 0.004898
Saving checkpoint... 
Iteration: 1494535965, states[0] = 16.799217, states[40]= 0.005320
Saving checkpoint... 
Iteration: 1506412872, states[0] = -47.547096, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1518081226, states[0] = -14.265612, states[40]= 0.001742
Saving checkpoint... 
Iteration: 1529690451, states[0] = -95.343596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540982205, states[0] = -95.207328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552998790, states[0] = -95.249763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565062011, states[0] = -95.342311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576836749, states[0] = 14.189887, states[40]= 0.006176
Saving checkpoint... 
Iteration: 1588837521, states[0] = 13.809308, states[40]= 0.006118
Saving checkpoint... 
Iteration: 1600423699, states[0] = -95.304311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612331615, states[0] = -78.251536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624333555, states[0] = -81.854671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636076264, states[0] = -95.215610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648109853, states[0] = -95.285196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660164778, states[0] = -95.355187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671933927, states[0] = 15.344466, states[40]= 0.006420
Saving checkpoint... 
Iteration: 1683999096, states[0] = -35.748984, states[40]= 0.000240
Saving checkpoint... 
Iteration: 1695987675, states[0] = -23.447183, states[40]= 0.000803
Saving checkpoint... 
Iteration: 1707786200, states[0] = -95.239703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719836005, states[0] = -95.324390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731747743, states[0] = -94.785613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743560115, states[0] = -95.351186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755613341, states[0] = 22.142550, states[40]= 0.027018
Saving checkpoint... 
Iteration: 1767433524, states[0] = -81.962959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778892752, states[0] = -95.253723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790714583, states[0] = 21.841866, states[40]= 0.021551
Saving checkpoint... 
Iteration: 1802574234, states[0] = -0.657518, states[40]= 0.004271
Saving checkpoint... 
Iteration: 1814520134, states[0] = 20.399424, states[40]= 0.009012
Saving checkpoint... 
Iteration: 1826403130, states[0] = -95.103828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837987752, states[0] = -95.110061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850010606, states[0] = 22.106393, states[40]= 0.046719
Saving checkpoint... 
Iteration: 1861626893, states[0] = -44.133276, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1873478967, states[0] = -95.091864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885437917, states[0] = -95.082129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897232763, states[0] = -94.946227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909226903, states[0] = -94.935468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921209999, states[0] = -94.904501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932907423, states[0] = -95.069928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944656247, states[0] = -79.686883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956581964, states[0] = -2.941007, states[40]= 0.003738
Saving checkpoint... 
Iteration: 1968264469, states[0] = -94.984036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979946517, states[0] = -95.077601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991819645, states[0] = -95.030915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003700928, states[0] = -94.884400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015414569, states[0] = -95.070251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027264342, states[0] = -94.983357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039192500, states[0] = -94.866119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051281314, states[0] = -95.000756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063047608, states[0] = 12.777900, states[40]= 0.004900
Saving checkpoint... 
Iteration: 2075134460, states[0] = -51.349353, states[40]= 0.000023
Saving checkpoint... 
Iteration: 2087138466, states[0] = -55.805781, states[40]= 0.000011
Saving checkpoint... 
Iteration: 2098836077, states[0] = -95.040227, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.960919
 - CaMKt in component CaMK (millimolar): 0.007105
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.670281
 - nass in component intracellular_ions (millimolar): 6.670342
 - ki in component intracellular_ions (millimolar): 145.306357
 - kss in component intracellular_ions (millimolar): 145.306336
 - cansr in component intracellular_ions (millimolar): 1.314955
 - cajsr in component intracellular_ions (millimolar): 1.276579
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003597
 - hf in component INa (dimensionless): 0.881022
 - hs in component INa (dimensionless): 0.881017
 - j in component INa (dimensionless): 0.880989
 - hsp in component INa (dimensionless): 0.727758
 - jp in component INa (dimensionless): 0.880970
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710925
 - hLp in component INaL (dimensionless): 0.452087
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.619327
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.693975
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934565
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332984
 - xs1 in component IKs (dimensionless): 0.245026
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:11:08 (159081): called boinc_finish(0)

</stderr_txt>
]]>


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