𝕏

Task 54933621

Name HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_250_2
Workunit 26077921
Created 27 Jun 2024, 16:12:14 UTC
Sent 27 Jun 2024, 16:12:26 UTC
Report deadline 1 Jul 2024, 1:48:26 UTC
Received 30 Jun 2024, 16:55:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 14 min 37 sec
CPU time 2 hours 13 min 55 sec
Validate state Valid
Credit 65.88
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_250.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_250_2_r1829234560_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032552229718_ORdGradInc_k_24-Pueyo_APDR-conf_250_2_r1829234560_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 122.079004
     * GNaL_b in INaL: 0.006874
     * Gto_b in Ito: 0.066796
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032983
     * GKs_b in IKs: 0.001851
     * GK1_b in IK1: 0.144895
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 63.530542
     * GKb_b in IKb: 0.003883
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046519
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12157704, states[0] = -92.454390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24195445, states[0] = -94.702681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35934553, states[0] = -94.889792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48115328, states[0] = -38.903865, states[40]= 0.000150
Saving checkpoint... 
Iteration: 60044411, states[0] = 13.502537, states[40]= 0.005605
Saving checkpoint... 
Iteration: 72233796, states[0] = -94.743934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84228336, states[0] = -94.733114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96341436, states[0] = -94.839595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108498019, states[0] = -94.879918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120340531, states[0] = -94.837176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132524300, states[0] = 21.245866, states[40]= 0.008574
Saving checkpoint... 
Iteration: 144686937, states[0] = -94.649127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156651370, states[0] = -81.579934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168787412, states[0] = -94.799397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180396360, states[0] = -94.857853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192628768, states[0] = -52.487998, states[40]= 0.000018
Saving checkpoint... 
Iteration: 204482288, states[0] = -94.875349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216355156, states[0] = -94.842326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228447156, states[0] = -94.869716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240562716, states[0] = 5.495768, states[40]= 0.005023
Saving checkpoint... 
Iteration: 252519257, states[0] = 22.811477, states[40]= 0.012152
Saving checkpoint... 
Iteration: 264690891, states[0] = -94.657274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276356062, states[0] = -94.842592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288180940, states[0] = -94.628693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300186767, states[0] = -94.647604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312267579, states[0] = -94.779434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324407345, states[0] = -94.860572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336316312, states[0] = -94.820894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347948317, states[0] = -94.869779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360096537, states[0] = -19.500735, states[40]= 0.001029
Saving checkpoint... 
Iteration: 371948199, states[0] = -94.869743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384094801, states[0] = -17.800206, states[40]= 0.001181
Saving checkpoint... 
Iteration: 396188839, states[0] = -94.652548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407816052, states[0] = -94.820682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419934139, states[0] = -94.866949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432081125, states[0] = -5.457402, states[40]= 0.003438
Saving checkpoint... 
Iteration: 443973137, states[0] = -94.873780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456114384, states[0] = -37.080334, states[40]= 0.000195
Saving checkpoint... 
Iteration: 468268050, states[0] = -94.779854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480101366, states[0] = -24.230990, states[40]= 0.000745
Saving checkpoint... 
Iteration: 492228585, states[0] = -94.727656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504333290, states[0] = -94.831094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516275982, states[0] = -94.788019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528442817, states[0] = -94.868647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540498238, states[0] = -94.876938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552474584, states[0] = -94.873932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564698248, states[0] = -94.672485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576724983, states[0] = -94.721764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588852389, states[0] = -94.840744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600937459, states[0] = -94.867545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612891315, states[0] = -94.855706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624917359, states[0] = -94.863012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637112407, states[0] = -35.098642, states[40]= 0.000254
Saving checkpoint... 
Iteration: 649324160, states[0] = -94.825703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661594943, states[0] = -17.938970, states[40]= 0.001167
Saving checkpoint... 
Iteration: 674276053, states[0] = -94.788009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685931125, states[0] = -94.866170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698036932, states[0] = 16.698347, states[40]= 0.006094
Saving checkpoint... 
Iteration: 710193641, states[0] = -94.662918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722046142, states[0] = 12.925602, states[40]= 0.005527
Saving checkpoint... 
Iteration: 734195681, states[0] = -94.667156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746271672, states[0] = -94.783535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758269556, states[0] = -94.781313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770192157, states[0] = -94.659732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782097388, states[0] = -20.334590, states[40]= 0.000967
Saving checkpoint... 
Iteration: 794269405, states[0] = -94.781135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806447447, states[0] = -94.869383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818315647, states[0] = -94.820206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830585830, states[0] = -9.333413, states[40]= 0.002574
Saving checkpoint... 
Iteration: 842551323, states[0] = 10.704628, states[40]= 0.005352
Saving checkpoint... 
Iteration: 854358407, states[0] = -94.843308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866144572, states[0] = -71.376814, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878076450, states[0] = -2.137492, states[40]= 0.004104
Saving checkpoint... 
Iteration: 890155777, states[0] = -87.946005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902301402, states[0] = -94.810011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913938553, states[0] = -94.867609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926071308, states[0] = 1.004469, states[40]= 0.004585
Saving checkpoint... 
Iteration: 937864012, states[0] = -94.845641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949771275, states[0] = -94.783020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961778495, states[0] = -94.790251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973597491, states[0] = -20.435460, states[40]= 0.000960
Saving checkpoint... 
Iteration: 985575241, states[0] = -1.356762, states[40]= 0.004238
Saving checkpoint... 
Iteration: 997349968, states[0] = -94.839407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009184578, states[0] = -94.641295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021338929, states[0] = -94.833885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033646023, states[0] = -73.398502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044950067, states[0] = -94.869742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057118419, states[0] = -41.210252, states[40]= 0.000108
Saving checkpoint... 
Iteration: 1069253245, states[0] = -94.762361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081206626, states[0] = -94.688717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093287056, states[0] = -94.798102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105179337, states[0] = -94.620080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117322784, states[0] = -94.824622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129129849, states[0] = -53.685559, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1140929015, states[0] = -94.865478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153043265, states[0] = 14.130967, states[40]= 0.005658
Saving checkpoint... 
Iteration: 1165260463, states[0] = -94.771018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177284613, states[0] = -94.795870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189473382, states[0] = -94.873439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201450259, states[0] = -94.869698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213535703, states[0] = 17.179284, states[40]= 0.006212
Saving checkpoint... 
Iteration: 1225688001, states[0] = -94.650151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237485467, states[0] = -94.875054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249385620, states[0] = -94.853528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261496259, states[0] = -94.876349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273443684, states[0] = -94.868438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285227854, states[0] = -94.726082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297204774, states[0] = -94.685037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309287191, states[0] = -94.798111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321443845, states[0] = -94.868444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333323999, states[0] = -94.825259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345132692, states[0] = -56.904051, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1356692075, states[0] = -94.659256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368545354, states[0] = 13.257760, states[40]= 0.005560
Saving checkpoint... 
Iteration: 1380364863, states[0] = -94.845767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392417876, states[0] = -94.862752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404375179, states[0] = -94.849771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416344314, states[0] = -94.836447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428262523, states[0] = -94.773253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440347194, states[0] = -94.837854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452167816, states[0] = -94.275168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463773292, states[0] = -94.784835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475893697, states[0] = -94.856017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488105422, states[0] = -28.203684, states[40]= 0.000550
Saving checkpoint... 
Iteration: 1500103554, states[0] = -31.727079, states[40]= 0.000366
Saving checkpoint... 
Iteration: 1512045088, states[0] = 10.656485, states[40]= 0.006181
Saving checkpoint... 
Iteration: 1524004781, states[0] = 34.678183, states[40]= 0.106518
Saving checkpoint... 
Iteration: 1535739594, states[0] = 13.174016, states[40]= 0.006651
Saving checkpoint... 
Iteration: 1547601247, states[0] = -95.069134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559548760, states[0] = -94.765753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1571533902, states[0] = -86.813061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583579934, states[0] = -95.038237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595493201, states[0] = -32.878761, states[40]= 0.000336
Saving checkpoint... 
Iteration: 1607675195, states[0] = -95.180799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619587623, states[0] = -95.059791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631546184, states[0] = -94.634592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1643654595, states[0] = -95.163667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655393710, states[0] = -95.197137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667372509, states[0] = -95.181102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679485460, states[0] = -24.422906, states[40]= 0.000753
Saving checkpoint... 
Iteration: 1691356771, states[0] = -95.166648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703482631, states[0] = -21.258391, states[40]= 0.000967
Saving checkpoint... 
Iteration: 1715419297, states[0] = 22.329948, states[40]= 0.013547
Saving checkpoint... 
Iteration: 1727314730, states[0] = -95.112509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739371318, states[0] = -95.180454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751040641, states[0] = -95.148887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762829323, states[0] = 17.935706, states[40]= 0.008136
Saving checkpoint... 
Iteration: 1774727981, states[0] = -95.132423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786780545, states[0] = -95.188080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798880179, states[0] = -18.509535, states[40]= 0.001222
Saving checkpoint... 
Iteration: 1810465994, states[0] = -94.930262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822519857, states[0] = 22.284117, states[40]= 0.011312
Saving checkpoint... 
Iteration: 1834486226, states[0] = -94.905660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846582340, states[0] = -7.233091, states[40]= 0.003058
Saving checkpoint... 
Iteration: 1858671646, states[0] = -94.545716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870524523, states[0] = 21.084419, states[40]= 0.008468
Saving checkpoint... 
Iteration: 1882575406, states[0] = -1.684588, states[40]= 0.004190
Saving checkpoint... 
Iteration: 1894665242, states[0] = -93.998028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1906589737, states[0] = -13.091410, states[40]= 0.001828
Saving checkpoint... 
Iteration: 1918654924, states[0] = -87.077892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930652340, states[0] = -83.222697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942662982, states[0] = -93.394341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954516415, states[0] = 23.639793, states[40]= 0.016889
Saving checkpoint... 
Iteration: 1966423970, states[0] = -94.864610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978289156, states[0] = -94.799979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990402286, states[0] = -94.858645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002243653, states[0] = -94.749513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014398366, states[0] = -94.857308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026155188, states[0] = -87.192986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038205394, states[0] = -94.685916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050330350, states[0] = -94.828678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062291189, states[0] = -94.801199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074440362, states[0] = -94.867377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086468216, states[0] = -94.872205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098465652, states[0] = -94.871799, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.752197
 - CaMKt in component CaMK (millimolar): 0.006634
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.785715
 - nass in component intracellular_ions (millimolar): 6.785774
 - ki in component intracellular_ions (millimolar): 145.195683
 - kss in component intracellular_ions (millimolar): 145.195663
 - cansr in component intracellular_ions (millimolar): 1.301018
 - cajsr in component intracellular_ions (millimolar): 1.264051
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003674
 - hf in component INa (dimensionless): 0.877380
 - hs in component INa (dimensionless): 0.877375
 - j in component INa (dimensionless): 0.877347
 - hsp in component INa (dimensionless): 0.720911
 - jp in component INa (dimensionless): 0.877328
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706906
 - hLp in component INaL (dimensionless): 0.450317
 - a in component Ito (dimensionless): 0.000630
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.624703
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.699399
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935456
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001580
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.347386
 - xs1 in component IKs (dimensionless): 0.235720
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997376
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:55:25 (158950): called boinc_finish(0)

</stderr_txt>
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