𝕏

Task 54933618

Name HuVeMOp_20240627032541665116_ORdGradInc_k_24-Pueyo_APDR-conf_4_2
Workunit 26077689
Created 27 Jun 2024, 16:12:14 UTC
Sent 27 Jun 2024, 16:12:26 UTC
Report deadline 1 Jul 2024, 1:48:26 UTC
Received 30 Jun 2024, 13:54:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241013
Run time 2 hours 15 min 39 sec
CPU time 2 hours 14 min 51 sec
Validate state Valid
Credit 63.69
Device peak FLOPS 5.56 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.75 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032541665116_ORdGradInc_k_24-Pueyo_APDR-conf_4.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032541665116_ORdGradInc_k_24-Pueyo_APDR-conf_4_2_r1842950031_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627032541665116_ORdGradInc_k_24-Pueyo_APDR-conf_4_2_r1842950031_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 124.345729
     * GNaL_b in INaL: 0.006183
     * Gto_b in Ito: 0.077107
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033491
     * GKs_b in IKs: 0.001843
     * GK1_b in IK1: 0.164107
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 62.001858
     * GKb_b in IKb: 0.003912
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034851
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11853726, states[0] = -95.114272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23820046, states[0] = -95.082984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35839907, states[0] = -95.085608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47571341, states[0] = 0.107630, states[40]= 0.004414
Saving checkpoint... 
Iteration: 59439110, states[0] = -95.109029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71463132, states[0] = -95.110929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83239194, states[0] = -94.989548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95276672, states[0] = -95.029948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107304483, states[0] = -95.051202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119158377, states[0] = -93.860275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130990395, states[0] = -95.110135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142974347, states[0] = -95.107759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154482550, states[0] = -95.108646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166555212, states[0] = 8.488395, states[40]= 0.005095
Saving checkpoint... 
Iteration: 178514566, states[0] = 22.829593, states[40]= 0.021665
Saving checkpoint... 
Iteration: 190046826, states[0] = 12.077614, states[40]= 0.005305
Saving checkpoint... 
Iteration: 201736430, states[0] = -94.981823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213695764, states[0] = -94.913456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225397217, states[0] = -95.091360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237166347, states[0] = -94.769779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248744478, states[0] = -94.992309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260861978, states[0] = -95.079430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272676580, states[0] = -94.870213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284523240, states[0] = 20.609342, states[40]= 0.008495
Saving checkpoint... 
Iteration: 296155767, states[0] = -92.632045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307900395, states[0] = -95.092136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319482401, states[0] = -95.107996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331288649, states[0] = -95.037224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343313047, states[0] = -95.054690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355067547, states[0] = 2.565916, states[40]= 0.004692
Saving checkpoint... 
Iteration: 367022238, states[0] = 20.889630, states[40]= 0.009018
Saving checkpoint... 
Iteration: 378759022, states[0] = -95.009306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390252057, states[0] = -95.001423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402230384, states[0] = -94.972992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414253172, states[0] = -95.002708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425882336, states[0] = -95.086633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437494302, states[0] = -95.109377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449515005, states[0] = 22.722335, states[40]= 0.020097
Saving checkpoint... 
Iteration: 461266695, states[0] = -95.017307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473341023, states[0] = -95.070116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485436935, states[0] = -95.100589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498039177, states[0] = 15.157183, states[40]= 0.005651
Saving checkpoint... 
Iteration: 510479320, states[0] = -95.107479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522895601, states[0] = -95.090653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535157786, states[0] = -93.622587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547568933, states[0] = 1.816494, states[40]= 0.004614
Saving checkpoint... 
Iteration: 559661911, states[0] = -94.506028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571821385, states[0] = -95.059627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584038317, states[0] = 15.489864, states[40]= 0.005708
Saving checkpoint... 
Iteration: 595921847, states[0] = -95.097337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608092218, states[0] = -16.380874, states[40]= 0.001327
Saving checkpoint... 
Iteration: 620069685, states[0] = 1.399715, states[40]= 0.004567
Saving checkpoint... 
Iteration: 632306512, states[0] = -95.050250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644206450, states[0] = -94.933522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656296710, states[0] = -95.043284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668336993, states[0] = -95.068022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680559473, states[0] = 6.564162, states[40]= 0.004992
Saving checkpoint... 
Iteration: 692619066, states[0] = -43.755685, states[40]= 0.000073
Saving checkpoint... 
Iteration: 704505112, states[0] = 30.339955, states[40]= 0.139442
Saving checkpoint... 
Iteration: 716570533, states[0] = 0.920450, states[40]= 0.004510
Saving checkpoint... 
Iteration: 728422165, states[0] = -95.097334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740536908, states[0] = 16.027643, states[40]= 0.005812
Saving checkpoint... 
Iteration: 752613691, states[0] = -38.016364, states[40]= 0.000169
Saving checkpoint... 
Iteration: 764574678, states[0] = -1.588569, states[40]= 0.004149
Saving checkpoint... 
Iteration: 776697309, states[0] = -94.916083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788244245, states[0] = -94.991666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800369213, states[0] = -95.081861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812373954, states[0] = -95.083566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824426855, states[0] = -95.098316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836459394, states[0] = -95.104385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848369652, states[0] = -95.081995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860555768, states[0] = 8.249681, states[40]= 0.005082
Saving checkpoint... 
Iteration: 872136558, states[0] = -64.451475, states[40]= 0.000002
Saving checkpoint... 
Iteration: 884227518, states[0] = -94.968469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896257600, states[0] = -95.007447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907981819, states[0] = -95.107582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920078540, states[0] = -4.237066, states[40]= 0.003660
Saving checkpoint... 
Iteration: 932135419, states[0] = -62.975148, states[40]= 0.000003
Saving checkpoint... 
Iteration: 943637307, states[0] = -65.442917, states[40]= 0.000002
Saving checkpoint... 
Iteration: 955757245, states[0] = -95.007019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967776616, states[0] = -95.026533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979566253, states[0] = 3.246049, states[40]= 0.004756
Saving checkpoint... 
Iteration: 991391073, states[0] = -95.089052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003522081, states[0] = 20.932904, states[40]= 0.009110
Saving checkpoint... 
Iteration: 1015380959, states[0] = -95.085846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027433303, states[0] = -95.099554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039451722, states[0] = -95.102997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051330655, states[0] = -95.064526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063481166, states[0] = -95.107409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075421809, states[0] = -95.097056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087431883, states[0] = -95.099229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099467456, states[0] = -95.105478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111034373, states[0] = 16.970138, states[40]= 0.006039
Saving checkpoint... 
Iteration: 1123077331, states[0] = -3.370660, states[40]= 0.003831
Saving checkpoint... 
Iteration: 1135073223, states[0] = -0.673217, states[40]= 0.004293
Saving checkpoint... 
Iteration: 1146836357, states[0] = -95.067431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158911531, states[0] = -95.094567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170909793, states[0] = -95.094124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182517805, states[0] = 22.038505, states[40]= 0.013424
Saving checkpoint... 
Iteration: 1194388863, states[0] = -95.088265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206225374, states[0] = -94.965028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218278680, states[0] = -95.028252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230046555, states[0] = 12.193479, states[40]= 0.005313
Saving checkpoint... 
Iteration: 1241934817, states[0] = -95.099738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254030463, states[0] = 18.350275, states[40]= 0.006532
Saving checkpoint... 
Iteration: 1266096222, states[0] = -20.371154, states[40]= 0.000951
Saving checkpoint... 
Iteration: 1277964073, states[0] = -95.104867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289881859, states[0] = -95.085987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301914501, states[0] = -95.095216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313840199, states[0] = -95.069239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325929056, states[0] = -95.098502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337840130, states[0] = -95.069192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349420216, states[0] = -95.096538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361495028, states[0] = -95.108936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373353095, states[0] = -95.075107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385253475, states[0] = -95.002504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397491712, states[0] = -95.108530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409230016, states[0] = -94.971878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421343428, states[0] = -95.070725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433326982, states[0] = -95.062315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445066461, states[0] = 3.138083, states[40]= 0.004746
Saving checkpoint... 
Iteration: 1457133352, states[0] = -60.374343, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1469097093, states[0] = -21.241613, states[40]= 0.000893
Saving checkpoint... 
Iteration: 1480872538, states[0] = -95.082683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492690630, states[0] = -94.902217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504601160, states[0] = -40.335172, states[40]= 0.000117
Saving checkpoint... 
Iteration: 1516551817, states[0] = 6.295094, states[40]= 0.005630
Saving checkpoint... 
Iteration: 1528575401, states[0] = -12.957353, states[40]= 0.002052
Saving checkpoint... 
Iteration: 1540600085, states[0] = -41.748676, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1551905064, states[0] = 31.820897, states[40]= 0.120178
Saving checkpoint... 
Iteration: 1563937288, states[0] = 13.520860, states[40]= 0.006626
Saving checkpoint... 
Iteration: 1575728868, states[0] = -85.405922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587850623, states[0] = -95.344014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599875700, states[0] = -95.367674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611658789, states[0] = 0.885269, states[40]= 0.005067
Saving checkpoint... 
Iteration: 1623421359, states[0] = -72.224239, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1635448305, states[0] = -95.135656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646985200, states[0] = -95.377262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659047382, states[0] = 7.959910, states[40]= 0.005886
Saving checkpoint... 
Iteration: 1670877037, states[0] = -95.234658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682792975, states[0] = -34.731033, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1694364237, states[0] = -95.361561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706134266, states[0] = 14.860425, states[40]= 0.006953
Saving checkpoint... 
Iteration: 1717857773, states[0] = 1.527376, states[40]= 0.005162
Saving checkpoint... 
Iteration: 1729897592, states[0] = -40.157482, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1741752391, states[0] = -95.350713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753759004, states[0] = -95.357005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765561890, states[0] = -1.465064, states[40]= 0.004676
Saving checkpoint... 
Iteration: 1777518994, states[0] = 21.395886, states[40]= 0.013186
Saving checkpoint... 
Iteration: 1789480406, states[0] = -95.374539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801267888, states[0] = -95.085504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813089639, states[0] = -16.869783, states[40]= 0.001296
Saving checkpoint... 
Iteration: 1824835030, states[0] = -95.100760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836528407, states[0] = 18.719622, states[40]= 0.006863
Saving checkpoint... 
Iteration: 1848574846, states[0] = -2.353161, states[40]= 0.004037
Saving checkpoint... 
Iteration: 1860497591, states[0] = -95.121612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872325404, states[0] = -95.070295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884406902, states[0] = -95.099415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895860457, states[0] = -95.082531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907860264, states[0] = -95.081101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919805788, states[0] = -95.051400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931547666, states[0] = 11.701103, states[40]= 0.005279
Saving checkpoint... 
Iteration: 1943568042, states[0] = 2.265566, states[40]= 0.004663
Saving checkpoint... 
Iteration: 1955533384, states[0] = 17.315784, states[40]= 0.006145
Saving checkpoint... 
Iteration: 1966971180, states[0] = -95.106124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978962112, states[0] = -95.104577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990778705, states[0] = -95.028120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002715601, states[0] = -94.949029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014694551, states[0] = -94.910018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2026454406, states[0] = -95.102964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038513728, states[0] = 23.047553, states[40]= 0.025225
Saving checkpoint... 
Iteration: 2050481121, states[0] = -95.106855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062393887, states[0] = -95.089274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074369530, states[0] = -95.081235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085970196, states[0] = -95.105292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097740930, states[0] = -94.986604, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.984913
 - CaMKt in component CaMK (millimolar): 0.006800
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.805518
 - nass in component intracellular_ions (millimolar): 6.805579
 - ki in component intracellular_ions (millimolar): 145.173236
 - kss in component intracellular_ions (millimolar): 145.173215
 - cansr in component intracellular_ions (millimolar): 1.309835
 - cajsr in component intracellular_ions (millimolar): 1.272744
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003588
 - hf in component INa (dimensionless): 0.881435
 - hs in component INa (dimensionless): 0.881430
 - j in component INa (dimensionless): 0.881403
 - hsp in component INa (dimensionless): 0.728539
 - jp in component INa (dimensionless): 0.881385
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713834
 - hLp in component INaL (dimensionless): 0.459804
 - a in component Ito (dimensionless): 0.000620
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.628865
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.705065
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938099
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334814
 - xs1 in component IKs (dimensionless): 0.232285
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997315
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:53:53 (158697): called boinc_finish(0)

</stderr_txt>
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