𝕏

Task 54932332

Name HuVeMOp_20240626065019623306_ORdGradInc_k_24-BASE_MID-conf_924_3
Workunit 26018968
Created 27 Jun 2024, 10:50:22 UTC
Sent 27 Jun 2024, 10:50:23 UTC
Report deadline 30 Jun 2024, 10:50:23 UTC
Received 30 Jun 2024, 2:52:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 6 min 23 sec
CPU time 2 hours 19 min 35 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-BASE_MID-conf_924.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-BASE_MID-conf_924_3_r114378944_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626065019623306_ORdGradInc_k_24-BASE_MID-conf_924_3_r114378944_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 98.883819
     * GNaL_b in INaL: 0.008404
     * Gto_b in Ito: 0.073668
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033918
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.152113
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 69.151461
     * GKb_b in IKb: 0.003910
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050432
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8896361, states[0] = -86.811684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 17469271, states[0] = -86.888689, states[40]= 0.000002
Saving checkpoint... 
Iteration: 26421835, states[0] = -86.882455, states[40]= 0.000002
Saving checkpoint... 
Iteration: 34773891, states[0] = -86.591618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44066703, states[0] = 22.000212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53690775, states[0] = -69.365725, states[40]= 0.000004
Saving checkpoint... 
Iteration: 61705222, states[0] = -85.551288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69972445, states[0] = -86.985376, states[40]= 0.000002
Saving checkpoint... 
Iteration: 78681526, states[0] = -60.996488, states[40]= 0.000013
Saving checkpoint... 
Iteration: 86932350, states[0] = -86.975192, states[40]= 0.000002
Saving checkpoint... 
Iteration: 96156741, states[0] = -36.285969, states[40]= 0.000218
Saving checkpoint... 
Iteration: 105021623, states[0] = 32.574735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113099685, states[0] = 6.019950, states[40]= 0.000024
Saving checkpoint... 
Iteration: 121075343, states[0] = 17.374553, states[40]= 0.000002
Saving checkpoint... 
Iteration: 130036971, states[0] = 30.745440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138928809, states[0] = -86.987062, states[40]= 0.000002
Saving checkpoint... 
Iteration: 147007537, states[0] = 26.419646, states[40]= -0.000000
Saving checkpoint... 
Iteration: 154471793, states[0] = -87.012982, states[40]= 0.000002
Saving checkpoint... 
Iteration: 162489481, states[0] = -87.020452, states[40]= 0.000002
Saving checkpoint... 
Iteration: 171786478, states[0] = -86.728224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180395162, states[0] = -86.958617, states[40]= 0.000002
Saving checkpoint... 
Iteration: 189669212, states[0] = -50.025772, states[40]= 0.000058
Saving checkpoint... 
Iteration: 198969683, states[0] = -87.012024, states[40]= 0.000002
Saving checkpoint... 
Iteration: 208348252, states[0] = -86.892404, states[40]= 0.000002
Saving checkpoint... 
Iteration: 216745865, states[0] = -86.527848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226698905, states[0] = -85.099873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235875157, states[0] = -86.933240, states[40]= 0.000002
Saving checkpoint... 
Iteration: 243578816, states[0] = 15.716821, states[40]= 0.000003
Saving checkpoint... 
Iteration: 251342081, states[0] = -86.879173, states[40]= 0.000002
Saving checkpoint... 
Iteration: 259853169, states[0] = -86.899006, states[40]= 0.000002
Saving checkpoint... 
Iteration: 268837237, states[0] = -86.868706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276976776, states[0] = -87.012093, states[40]= 0.000002
Saving checkpoint... 
Iteration: 286405144, states[0] = -86.964789, states[40]= 0.000002
Saving checkpoint... 
Iteration: 295216323, states[0] = -86.302508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305426790, states[0] = -86.982143, states[40]= 0.000002
Saving checkpoint... 
Iteration: 315251523, states[0] = -86.557443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324550905, states[0] = 26.750130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334982748, states[0] = -87.011784, states[40]= 0.000002
Saving checkpoint... 
Iteration: 343080262, states[0] = 15.067668, states[40]= 0.000003
Saving checkpoint... 
Iteration: 353048087, states[0] = 27.662778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361615431, states[0] = -3.387687, states[40]= 0.000086
Saving checkpoint... 
Iteration: 371730073, states[0] = -86.412630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379335278, states[0] = -86.859275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387631844, states[0] = -16.689261, states[40]= 0.000112
Saving checkpoint... 
Iteration: 395496303, states[0] = -87.013838, states[40]= 0.000002
Saving checkpoint... 
Iteration: 404587428, states[0] = 11.770401, states[40]= 0.000007
Saving checkpoint... 
Iteration: 414482335, states[0] = -87.007743, states[40]= 0.000002
Saving checkpoint... 
Iteration: 424166432, states[0] = -47.185181, states[40]= 0.000081
Saving checkpoint... 
Iteration: 432600210, states[0] = 5.484558, states[40]= 0.000027
Saving checkpoint... 
Iteration: 442189809, states[0] = -76.694322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450480850, states[0] = -87.005392, states[40]= 0.000002
Saving checkpoint... 
Iteration: 459121108, states[0] = -7.564049, states[40]= 0.000103
Saving checkpoint... 
Iteration: 467940577, states[0] = -86.983772, states[40]= 0.000002
Saving checkpoint... 
Iteration: 476463082, states[0] = -86.996109, states[40]= 0.000002
Saving checkpoint... 
Iteration: 484738416, states[0] = -86.466371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493902773, states[0] = -86.952398, states[40]= 0.000002
Saving checkpoint... 
Iteration: 502527556, states[0] = 32.255236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510691547, states[0] = -79.161735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519142390, states[0] = -25.369924, states[40]= 0.000244
Saving checkpoint... 
Iteration: 528839461, states[0] = -86.860501, states[40]= 0.000002
Saving checkpoint... 
Iteration: 537469035, states[0] = -86.996003, states[40]= 0.000002
Saving checkpoint... 
Iteration: 545450975, states[0] = -86.986282, states[40]= 0.000002
Saving checkpoint... 
Iteration: 553667096, states[0] = -47.863781, states[40]= 0.000074
Saving checkpoint... 
Iteration: 562130267, states[0] = -15.311221, states[40]= 0.000107
Saving checkpoint... 
Iteration: 570929324, states[0] = -86.971060, states[40]= 0.000002
Saving checkpoint... 
Iteration: 579753761, states[0] = -86.557035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587598663, states[0] = 6.284523, states[40]= 0.000023
Saving checkpoint... 
Iteration: 598105670, states[0] = 2.571170, states[40]= 0.000044
Saving checkpoint... 
Iteration: 606222138, states[0] = -86.338500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616488485, states[0] = -87.000275, states[40]= 0.000002
Saving checkpoint... 
Iteration: 624401504, states[0] = -86.944777, states[40]= 0.000002
Saving checkpoint... 
Iteration: 633862110, states[0] = -86.895291, states[40]= 0.000002
Saving checkpoint... 
Iteration: 642680024, states[0] = -62.492851, states[40]= 0.000011
Saving checkpoint... 
Iteration: 652160925, states[0] = -41.626054, states[40]= 0.000143
Saving checkpoint... 
Iteration: 660837713, states[0] = -86.850478, states[40]= 0.000002
Saving checkpoint... 
Iteration: 668257225, states[0] = -86.571827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 677020956, states[0] = 32.460995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686900837, states[0] = -86.941050, states[40]= 0.000002
Saving checkpoint... 
Iteration: 694593722, states[0] = 8.757217, states[40]= 0.000014
Saving checkpoint... 
Iteration: 703819096, states[0] = -86.805732, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711901124, states[0] = -86.940125, states[40]= 0.000002
Saving checkpoint... 
Iteration: 721109220, states[0] = 0.551442, states[40]= 0.000058
Saving checkpoint... 
Iteration: 729333690, states[0] = -86.838678, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739115164, states[0] = -3.187829, states[40]= 0.000084
Saving checkpoint... 
Iteration: 747414336, states[0] = -86.950592, states[40]= 0.000002
Saving checkpoint... 
Iteration: 757327709, states[0] = -86.823987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 765907976, states[0] = -86.944028, states[40]= 0.000002
Saving checkpoint... 
Iteration: 775779568, states[0] = -86.672713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785901987, states[0] = -86.937348, states[40]= 0.000002
Saving checkpoint... 
Iteration: 794506566, states[0] = 25.014021, states[40]= -0.000000
Saving checkpoint... 
Iteration: 803329995, states[0] = -86.826931, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812018386, states[0] = 32.215504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819652805, states[0] = -34.077621, states[40]= 0.000254
Saving checkpoint... 
Iteration: 830083064, states[0] = 13.804794, states[40]= 0.000004
Saving checkpoint... 
Iteration: 839805122, states[0] = -86.760172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847908949, states[0] = -86.940914, states[40]= 0.000002
Saving checkpoint... 
Iteration: 857335112, states[0] = -86.835400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865855968, states[0] = -86.874070, states[40]= 0.000002
Saving checkpoint... 
Iteration: 875391234, states[0] = -86.921735, states[40]= 0.000002
Saving checkpoint... 
Iteration: 883394804, states[0] = -86.925232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 891745353, states[0] = -86.491204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900325737, states[0] = -86.812355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908645444, states[0] = -27.814907, states[40]= 0.000278
Saving checkpoint... 
Iteration: 916628520, states[0] = -13.765770, states[40]= 0.000105
Saving checkpoint... 
Iteration: 926028586, states[0] = 32.152642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934840809, states[0] = -86.843228, states[40]= 0.000002
Saving checkpoint... 
Iteration: 944327625, states[0] = -86.814585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 952155484, states[0] = -36.474134, states[40]= 0.000219
Saving checkpoint... 
Iteration: 961386753, states[0] = -86.912425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 969952163, states[0] = -86.966261, states[40]= 0.000002
Saving checkpoint... 
Iteration: 980047328, states[0] = 27.911400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989426147, states[0] = -86.948282, states[40]= 0.000002
Saving checkpoint... 
Iteration: 998576154, states[0] = 16.903454, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1008948043, states[0] = -86.961972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1018175715, states[0] = -57.231928, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1026240421, states[0] = -86.452565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034552862, states[0] = 26.101430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043530542, states[0] = 31.898507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052690821, states[0] = -78.042691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060818003, states[0] = -86.785333, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1068620694, states[0] = -7.200968, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1077909853, states[0] = -86.930510, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1086282066, states[0] = -86.667461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094450924, states[0] = -86.959480, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1102598932, states[0] = 6.161979, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1111547693, states[0] = 27.800360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121021907, states[0] = 32.506091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129881198, states[0] = -86.897489, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1139853332, states[0] = -86.856213, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1148838748, states[0] = -86.828605, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1157523682, states[0] = 32.508736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167492303, states[0] = -86.974855, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1175754984, states[0] = -86.534072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1184105990, states[0] = 2.414257, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1192481112, states[0] = -86.969358, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1200812538, states[0] = -86.763786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209821773, states[0] = -86.787537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219068379, states[0] = 20.207769, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230330396, states[0] = -86.806825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240567906, states[0] = 20.402370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1249796530, states[0] = -86.712513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260195871, states[0] = -83.491662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270123266, states[0] = -9.257408, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1279269977, states[0] = -86.605567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288084793, states[0] = 13.018853, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1298037369, states[0] = 30.616459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308372038, states[0] = -86.876744, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1318397489, states[0] = -86.906799, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1328319231, states[0] = -86.775307, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338458510, states[0] = -86.951761, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1346906653, states[0] = -86.914433, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1355976611, states[0] = -86.959524, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1367395872, states[0] = -86.902700, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1377763343, states[0] = -86.568468, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387384721, states[0] = -86.889200, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1396831775, states[0] = -86.801698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1406009867, states[0] = 28.753394, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1414770504, states[0] = -86.601278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424141213, states[0] = -24.365814, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1433451404, states[0] = -86.943242, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1444134946, states[0] = -19.256404, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1453868011, states[0] = -86.863919, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1463144664, states[0] = -27.141345, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1472429101, states[0] = -86.926932, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1481813738, states[0] = -86.753250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1491210285, states[0] = -86.162086, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.837201
 - CaMKt in component CaMK (millimolar): 0.024084
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 8.037869
 - nass in component intracellular_ions (millimolar): 8.038015
 - ki in component intracellular_ions (millimolar): 143.424744
 - kss in component intracellular_ions (millimolar): 143.424706
 - cansr in component intracellular_ions (millimolar): 1.970865
 - cajsr in component intracellular_ions (millimolar): 1.900233
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.008154
 - hf in component INa (dimensionless): 0.660903
 - hs in component INa (dimensionless): 0.660871
 - j in component INa (dimensionless): 0.660691
 - hsp in component INa (dimensionless): 0.412930
 - jp in component INa (dimensionless): 0.660562
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.456971
 - hLp in component INaL (dimensionless): 0.222808
 - a in component Ito (dimensionless): 0.001074
 - iF in component Ito (dimensionless): 0.999465
 - iS in component Ito (dimensionless): 0.534744
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999465
 - iSp in component Ito (dimensionless): 0.578312
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.876692
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999610
 - jca in component ICaL (dimensionless): 0.999940
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003512
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.509366
 - xs1 in component IKs (dimensionless): 0.333824
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997022
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
04:52:01 (12340): called boinc_finish(0)

</stderr_txt>
]]>


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