𝕏

Task 54932278

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_57_2
Workunit 25855196
Created 27 Jun 2024, 9:57:51 UTC
Sent 27 Jun 2024, 9:57:56 UTC
Report deadline 30 Jun 2024, 9:57:56 UTC
Received 29 Jun 2024, 18:19:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 4 min 57 sec
CPU time 2 hours 20 min 38 sec
Validate state Valid
Credit 44.16
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 6.25 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_57.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_57_2_r1283357560_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_57_2_r1283357560_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 111.070697
     * GNaL_b in INaL: 0.009034
     * Gto_b in Ito: 0.087911
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032535
     * GKs_b in IKs: 0.001783
     * GK1_b in IK1: 0.154615
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 69.633094
     * GKb_b in IKb: 0.003961
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047156
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7929689, states[0] = -94.109977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17214707, states[0] = -94.031725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26252779, states[0] = -93.517008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36015548, states[0] = 31.803861, states[40]= 0.008462
Saving checkpoint... 
Iteration: 44448069, states[0] = -93.900683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53849301, states[0] = -93.932307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62119335, states[0] = -4.438313, states[40]= 0.003823
Saving checkpoint... 
Iteration: 71499603, states[0] = -93.936096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80770081, states[0] = -93.960817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90202950, states[0] = -68.371927, states[40]= 0.000014
Saving checkpoint... 
Iteration: 98757446, states[0] = -93.959688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108216516, states[0] = -84.168838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 117415125, states[0] = -93.935794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126362172, states[0] = -93.783353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136014439, states[0] = 31.749024, states[40]= 0.012656
Saving checkpoint... 
Iteration: 144815614, states[0] = -93.957994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152722781, states[0] = -93.958048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160666640, states[0] = -93.955475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170700385, states[0] = -93.957207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178378444, states[0] = -93.809601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187818267, states[0] = -93.924525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196525714, states[0] = -93.928714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205163689, states[0] = -93.944067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213785127, states[0] = -93.925090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222675550, states[0] = -93.955711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230647519, states[0] = -93.953547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238206600, states[0] = -71.950963, states[40]= 0.000007
Saving checkpoint... 
Iteration: 248336604, states[0] = -93.730286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257843386, states[0] = -93.923754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268788484, states[0] = -93.957753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278278348, states[0] = -93.547966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287002618, states[0] = -93.950681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296153284, states[0] = -28.901195, states[40]= 0.002984
Saving checkpoint... 
Iteration: 304671549, states[0] = -93.955229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312232808, states[0] = -93.065144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321589075, states[0] = -93.929418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330327452, states[0] = -93.707905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339121198, states[0] = -93.945459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348579916, states[0] = -93.943447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357618948, states[0] = -93.928560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366919917, states[0] = -93.953888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376569812, states[0] = -93.941161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385048700, states[0] = -93.948463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394119307, states[0] = -4.288596, states[40]= 0.003858
Saving checkpoint... 
Iteration: 403794669, states[0] = -93.924393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411497833, states[0] = -93.931743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419989879, states[0] = -93.920676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428899062, states[0] = -93.954523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439083148, states[0] = -93.946852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447476524, states[0] = -93.932292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458023674, states[0] = 31.797444, states[40]= 0.000613
Saving checkpoint... 
Iteration: 467846092, states[0] = -93.923200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478278930, states[0] = -93.549842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486752577, states[0] = -93.957364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497312743, states[0] = -93.937564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504164674, states[0] = -36.926437, states[40]= 0.001551
Saving checkpoint... 
Iteration: 512416552, states[0] = -93.857085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521362886, states[0] = -93.935755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529682749, states[0] = -93.926597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538878564, states[0] = -93.954985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547382922, states[0] = -93.935021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556273900, states[0] = -93.528929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565092967, states[0] = -93.946143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573693350, states[0] = -93.926246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581340441, states[0] = -93.936391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590377265, states[0] = -93.806683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598101543, states[0] = 5.748063, states[40]= 0.003755
Saving checkpoint... 
Iteration: 607270520, states[0] = -93.938862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617738519, states[0] = -93.925114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625943021, states[0] = -93.921018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636001243, states[0] = 50.040663, states[40]= 0.442526
Saving checkpoint... 
Iteration: 644861029, states[0] = -93.955302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653198837, states[0] = -93.941537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661360904, states[0] = -93.935502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670393139, states[0] = -93.829137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680198335, states[0] = -63.944691, states[40]= 0.000029
Saving checkpoint... 
Iteration: 687794058, states[0] = -93.923754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697152967, states[0] = -93.943307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705163199, states[0] = -93.942866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714561779, states[0] = -93.938443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725479608, states[0] = -93.931562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734348342, states[0] = -93.754736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743472879, states[0] = -93.931723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752060184, states[0] = 22.314103, states[40]= 0.000724
Saving checkpoint... 
Iteration: 760333464, states[0] = -93.721699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768680612, states[0] = -93.954713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778441346, states[0] = -93.879609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787527731, states[0] = -93.930022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796027108, states[0] = 31.366861, states[40]= 0.000277
Saving checkpoint... 
Iteration: 806773969, states[0] = -93.956627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817057004, states[0] = -93.947115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827037683, states[0] = -93.947928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835577694, states[0] = -93.928539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844792904, states[0] = -93.956372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854267362, states[0] = -93.500070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864185592, states[0] = -53.270186, states[40]= 0.000171
Saving checkpoint... 
Iteration: 872409289, states[0] = -93.848363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882658169, states[0] = -93.952936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892344896, states[0] = -93.747166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901458738, states[0] = -93.931790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910928157, states[0] = -93.952325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920299529, states[0] = -93.624837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928405159, states[0] = -93.843489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937591446, states[0] = -93.927941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947632992, states[0] = -93.926852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955912291, states[0] = -93.920818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964630069, states[0] = -93.950013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974265154, states[0] = -93.489981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983684533, states[0] = -93.925514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992544781, states[0] = -93.933118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001329093, states[0] = -93.935828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011283008, states[0] = -93.937472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020936641, states[0] = -93.951739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030284136, states[0] = -93.569117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040409294, states[0] = -93.847982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049276965, states[0] = -93.937609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058545355, states[0] = -93.933139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067063291, states[0] = -93.946272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077253406, states[0] = -93.938433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087352059, states[0] = -93.934830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096447101, states[0] = -93.883505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105149947, states[0] = -93.942499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114473055, states[0] = -93.901414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123510099, states[0] = -93.929756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133005067, states[0] = -93.948634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141257985, states[0] = -93.938113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149622841, states[0] = -93.926645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158670147, states[0] = -93.953181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166014757, states[0] = 31.795355, states[40]= 0.011339
Saving checkpoint... 
Iteration: 1174873453, states[0] = -93.953700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183719569, states[0] = -93.924243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193968184, states[0] = -93.919274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202916939, states[0] = -93.952090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211883655, states[0] = -93.920767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220331438, states[0] = -93.715748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229576430, states[0] = -93.927671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238849356, states[0] = -93.954286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246640994, states[0] = -93.950556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255662895, states[0] = -93.925409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263389109, states[0] = -93.933177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271739699, states[0] = -93.923589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281166738, states[0] = -93.941403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289139481, states[0] = -93.942515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298027241, states[0] = 31.347090, states[40]= 0.000271
Saving checkpoint... 
Iteration: 1307938139, states[0] = -93.919542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316830993, states[0] = -93.954587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324890428, states[0] = -93.952783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333989332, states[0] = -93.918590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1342691607, states[0] = -93.953964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351853081, states[0] = -93.921036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362665438, states[0] = -93.952390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373509849, states[0] = -93.929191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382297090, states[0] = -93.615498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390933465, states[0] = -93.951019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399721849, states[0] = -93.923697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407785908, states[0] = -93.922276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415424523, states[0] = -93.931680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423786812, states[0] = -93.922220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431851391, states[0] = -93.920886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441488455, states[0] = -93.929660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451851907, states[0] = -93.920830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462738950, states[0] = -93.955019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472932653, states[0] = -93.950864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481862826, states[0] = -93.920548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491295888, states[0] = -93.935899, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.793999
 - CaMKt in component CaMK (millimolar): 0.002092
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.700075
 - nass in component intracellular_ions (millimolar): 6.700198
 - ki in component intracellular_ions (millimolar): 145.159890
 - kss in component intracellular_ions (millimolar): 145.159879
 - cansr in component intracellular_ions (millimolar): 1.829926
 - cajsr in component intracellular_ions (millimolar): 1.829755
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004047
 - hf in component INa (dimensionless): 0.859409
 - hs in component INa (dimensionless): 0.859410
 - j in component INa (dimensionless): 0.859414
 - hsp in component INa (dimensionless): 0.688191
 - jp in component INa (dimensionless): 0.859416
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699027
 - hLp in component INaL (dimensionless): 0.503123
 - a in component Ito (dimensionless): 0.000672
 - iF in component Ito (dimensionless): 0.999842
 - iS in component Ito (dimensionless): 0.991212
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999842
 - iSp in component Ito (dimensionless): 0.996450
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996223
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005240
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008346
 - xs1 in component IKs (dimensionless): 0.043269
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997613
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
20:19:35 (10888): called boinc_finish(0)

</stderr_txt>
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