𝕏

Task 54932277

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_257_2
Workunit 25855192
Created 27 Jun 2024, 9:57:51 UTC
Sent 27 Jun 2024, 9:57:56 UTC
Report deadline 30 Jun 2024, 9:57:56 UTC
Received 29 Jun 2024, 9:00:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 10 min 33 sec
CPU time 2 hours 20 min 5 sec
Validate state Valid
Credit 45.71
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.18 MB
Peak swap size 6.25 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_257.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_257_2_r875290976_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_4000-conf_257_2_r875290976_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 120.436396
     * GNaL_b in INaL: 0.006718
     * Gto_b in Ito: 0.088429
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032627
     * GKs_b in IKs: 0.001759
     * GK1_b in IK1: 0.147401
     * Gncx_b in INaCa_i: 0.000960
     * Pnak_b in INaK: 64.825196
     * GKb_b in IKb: 0.003869
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051309
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8965939, states[0] = -93.876235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17273136, states[0] = -93.798990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25687298, states[0] = -93.752305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34959929, states[0] = -93.760427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44485194, states[0] = -93.713998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54674177, states[0] = -93.757076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61787703, states[0] = -93.723496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69449831, states[0] = -93.733194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77643996, states[0] = -93.728341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86439750, states[0] = -93.683492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95198511, states[0] = -93.745183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104775922, states[0] = -93.763046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114417661, states[0] = -93.664596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123264737, states[0] = -93.744099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131701940, states[0] = -93.730521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139901468, states[0] = -93.726424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147835922, states[0] = -93.727928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155821968, states[0] = -93.728370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164413515, states[0] = -93.661560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172628707, states[0] = -93.759329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180519291, states[0] = -93.734105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189926138, states[0] = -93.726629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198559014, states[0] = -93.746943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207148368, states[0] = -93.750348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215632666, states[0] = -93.733275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224179318, states[0] = -55.542235, states[40]= 0.000105
Saving checkpoint... 
Iteration: 232952523, states[0] = -93.759455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241030783, states[0] = -93.755817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249163543, states[0] = -93.749697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258369804, states[0] = -93.602151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266256363, states[0] = -93.250388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274812117, states[0] = -93.764641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285231364, states[0] = -93.746733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294858555, states[0] = -93.763233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304257616, states[0] = -93.256482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312417340, states[0] = -93.665880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321312467, states[0] = -93.743421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330646103, states[0] = -93.761192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339342676, states[0] = -93.742245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349764034, states[0] = -93.729897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359537496, states[0] = -93.735742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368249673, states[0] = -93.216142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377912635, states[0] = -93.726739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386760713, states[0] = -93.765163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394704842, states[0] = -93.764475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403389850, states[0] = -93.740402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413602185, states[0] = -93.733783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423174376, states[0] = -93.748879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431085911, states[0] = -93.752870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440020571, states[0] = 31.295477, states[40]= 0.001612
Saving checkpoint... 
Iteration: 448244021, states[0] = -93.184230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457560563, states[0] = -93.734849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466449307, states[0] = -93.694530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475777629, states[0] = -93.729306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485190298, states[0] = -93.748043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494062981, states[0] = 19.977537, states[40]= 0.000952
Saving checkpoint... 
Iteration: 502427317, states[0] = -93.675484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510067218, states[0] = 18.403212, states[40]= 0.001178
Saving checkpoint... 
Iteration: 518522863, states[0] = -93.735060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526498050, states[0] = -93.724448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535247314, states[0] = -93.745524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544009022, states[0] = 30.056897, states[40]= 0.083406
Saving checkpoint... 
Iteration: 551381280, states[0] = -93.740366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559667937, states[0] = -93.731719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568899123, states[0] = -93.761085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578555421, states[0] = -93.745348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587614652, states[0] = -93.733046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596036635, states[0] = 28.471232, states[40]= 0.000232
Saving checkpoint... 
Iteration: 604421993, states[0] = -93.670018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613524816, states[0] = -93.735539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622769607, states[0] = -93.764571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631855770, states[0] = -93.727281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641821378, states[0] = -93.727974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650699119, states[0] = -93.763702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659666415, states[0] = -93.731528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667924568, states[0] = -93.725848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676607279, states[0] = -93.755783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685334119, states[0] = -93.741776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694856368, states[0] = -93.762411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704272811, states[0] = -93.325902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711913145, states[0] = -93.725964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720001451, states[0] = 50.156969, states[40]= 0.543053
Saving checkpoint... 
Iteration: 728241347, states[0] = -93.166130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737387828, states[0] = -93.739708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746512722, states[0] = -93.730522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755418361, states[0] = -93.738611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764739690, states[0] = -93.764270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774890447, states[0] = -93.760962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783413801, states[0] = -93.738702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792659324, states[0] = -93.761234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803022330, states[0] = -93.755001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811974852, states[0] = -93.724593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821372932, states[0] = -93.740044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828865700, states[0] = -93.761777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836926245, states[0] = -93.759328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845070322, states[0] = -93.752649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853496229, states[0] = -93.735860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861575874, states[0] = -93.733486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870579222, states[0] = -93.750336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879493479, states[0] = -93.735885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887930344, states[0] = -93.725234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897343976, states[0] = -93.740923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906891755, states[0] = -93.760608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915538401, states[0] = -93.734443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925730431, states[0] = -93.729354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935048704, states[0] = -93.753457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943168952, states[0] = -93.747926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952517301, states[0] = -93.731914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960869235, states[0] = -93.761346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969813975, states[0] = -93.727378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977912280, states[0] = -93.725370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987423722, states[0] = -93.737898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996256842, states[0] = -93.251068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005266580, states[0] = -93.743663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015343033, states[0] = -93.740687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024659302, states[0] = -93.760702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031734705, states[0] = -93.729010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039847782, states[0] = -93.726508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047363874, states[0] = -93.739851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056067405, states[0] = 18.333087, states[40]= 0.001189
Saving checkpoint... 
Iteration: 1063865866, states[0] = -93.726085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072329285, states[0] = -93.516304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081210328, states[0] = -93.745818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090179900, states[0] = -56.007541, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1099105921, states[0] = -93.750414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107950786, states[0] = -93.724349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117958701, states[0] = -93.724182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127396903, states[0] = -93.738496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137583197, states[0] = -93.732647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147007477, states[0] = -93.754912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156694760, states[0] = -93.762383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165527892, states[0] = -93.734181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174051955, states[0] = 23.846260, states[40]= 0.000528
Saving checkpoint... 
Iteration: 1182061349, states[0] = 20.571777, states[40]= 0.000875
Saving checkpoint... 
Iteration: 1191795547, states[0] = -93.727267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199682234, states[0] = -93.729891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207870966, states[0] = -93.725651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216268740, states[0] = -93.306639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224288111, states[0] = -93.387161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232339515, states[0] = -93.540476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240366312, states[0] = -93.593956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249439257, states[0] = -93.736777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257883040, states[0] = -93.725296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266720209, states[0] = -93.762867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275456881, states[0] = -93.736139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285057914, states[0] = -93.752223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293329621, states[0] = -93.740550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301354078, states[0] = -93.739625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310281569, states[0] = -93.361293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318486936, states[0] = -93.716978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328431095, states[0] = -93.677138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336492792, states[0] = -93.719994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344644880, states[0] = -93.758768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353624618, states[0] = -93.731021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363431645, states[0] = -93.736769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372215798, states[0] = -89.951142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381018713, states[0] = -93.753848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390503705, states[0] = -93.725118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398838202, states[0] = -93.761390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409251880, states[0] = -93.743333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418111892, states[0] = -3.083592, states[40]= 0.003872
Saving checkpoint... 
Iteration: 1428237699, states[0] = -93.134510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437345353, states[0] = -93.739634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446022508, states[0] = 31.146978, states[40]= 0.000882
Saving checkpoint... 
Iteration: 1455496341, states[0] = -93.734475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463493698, states[0] = -93.734539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470782407, states[0] = -93.762493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478755001, states[0] = -93.762682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486806830, states[0] = -93.762019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495413835, states[0] = -93.737068, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.598538
 - CaMKt in component CaMK (millimolar): 0.002092
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.879693
 - nass in component intracellular_ions (millimolar): 6.879815
 - ki in component intracellular_ions (millimolar): 144.978547
 - kss in component intracellular_ions (millimolar): 144.978537
 - cansr in component intracellular_ions (millimolar): 1.839415
 - cajsr in component intracellular_ions (millimolar): 1.839319
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004127
 - hf in component INa (dimensionless): 0.855483
 - hs in component INa (dimensionless): 0.855484
 - j in component INa (dimensionless): 0.855489
 - hsp in component INa (dimensionless): 0.681259
 - jp in component INa (dimensionless): 0.855491
 - mL in component INaL (dimensionless): 0.000064
 - hL in component INaL (dimensionless): 0.693509
 - hLp in component INaL (dimensionless): 0.496648
 - a in component Ito (dimensionless): 0.000681
 - iF in component Ito (dimensionless): 0.999836
 - iS in component Ito (dimensionless): 0.991265
 - ap in component Ito (dimensionless): 0.000347
 - iFp in component Ito (dimensionless): 0.999836
 - iSp in component Ito (dimensionless): 0.996452
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996476
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005332
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008452
 - xs1 in component IKs (dimensionless): 0.041209
 - xs2 in component IKs (dimensionless): 0.000102
 - xk1 in component IK1 (dimensionless): 0.997659
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:00:16 (12620): called boinc_finish(0)

</stderr_txt>
]]>


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