𝕏

Task 54932276

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_2000-conf_857_2
Workunit 25855179
Created 27 Jun 2024, 9:57:51 UTC
Sent 27 Jun 2024, 9:57:56 UTC
Report deadline 30 Jun 2024, 9:57:56 UTC
Received 29 Jun 2024, 9:02:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 6 min 34 sec
CPU time 2 hours 20 min 23 sec
Validate state Valid
Credit 43.00
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.24 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_2000-conf_857.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_2000-conf_857_2_r1292879130_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_ENDO_2000-conf_857_2_r1292879130_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.030048
     * GNaL_b in INaL: 0.007653
     * Gto_b in Ito: 0.076346
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032559
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.168390
     * Gncx_b in INaCa_i: 0.000946
     * Pnak_b in INaK: 68.251030
     * GKb_b in IKb: 0.003820
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034585
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8394286, states[0] = -94.127272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18150292, states[0] = -35.225858, states[40]= 0.001296
Saving checkpoint... 
Iteration: 26372180, states[0] = -94.002857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35350576, states[0] = -93.962230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44360219, states[0] = -93.975289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52375814, states[0] = -93.997489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62623323, states[0] = -94.114626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72137199, states[0] = -24.932941, states[40]= 0.002325
Saving checkpoint... 
Iteration: 82339042, states[0] = -93.945542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91928666, states[0] = -94.115223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100284309, states[0] = -93.810854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109428465, states[0] = -94.057100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118892698, states[0] = -94.118867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128662904, states[0] = -94.123520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138108766, states[0] = -2.559757, states[40]= 0.003573
Saving checkpoint... 
Iteration: 146812437, states[0] = -94.123095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155657074, states[0] = -94.123834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164736624, states[0] = -94.125122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174890319, states[0] = -94.120078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183342268, states[0] = -93.955602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193129240, states[0] = -18.968597, states[40]= 0.001726
Saving checkpoint... 
Iteration: 201983047, states[0] = -94.115415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210393813, states[0] = -94.027546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219096511, states[0] = 4.648632, states[40]= 0.003105
Saving checkpoint... 
Iteration: 227207532, states[0] = -91.481329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236582576, states[0] = -94.117225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244869448, states[0] = -94.120987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254214929, states[0] = -93.246702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263455260, states[0] = -94.076281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272369730, states[0] = -93.998335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282452685, states[0] = -94.074688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290940975, states[0] = -94.117291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300726822, states[0] = -94.124938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310757351, states[0] = -94.124532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318859741, states[0] = -94.121079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327310090, states[0] = -93.886678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334592039, states[0] = -94.118071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342253630, states[0] = -93.696160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350899707, states[0] = -94.119057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360515411, states[0] = -94.101813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368747624, states[0] = -94.124396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377259187, states[0] = -93.719573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386119608, states[0] = -10.902533, states[40]= 0.002376
Saving checkpoint... 
Iteration: 395161175, states[0] = -44.033302, states[40]= 0.000562
Saving checkpoint... 
Iteration: 403058026, states[0] = 21.332782, states[40]= 0.000498
Saving checkpoint... 
Iteration: 412708505, states[0] = -94.124355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422813701, states[0] = -94.122396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430955715, states[0] = -94.115816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440851403, states[0] = -94.120815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449501821, states[0] = -94.096793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457126384, states[0] = -16.615109, states[40]= 0.001720
Saving checkpoint... 
Iteration: 465379216, states[0] = -94.009615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474109409, states[0] = -3.030954, states[40]= 0.003539
Saving checkpoint... 
Iteration: 484402648, states[0] = -94.035246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493683437, states[0] = -94.123580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502683723, states[0] = -94.123540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511801079, states[0] = -94.122365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520881505, states[0] = -94.119047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528073160, states[0] = 15.328576, states[40]= 0.001180
Saving checkpoint... 
Iteration: 537498837, states[0] = -94.095246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545165357, states[0] = -47.563953, states[40]= 0.000352
Saving checkpoint... 
Iteration: 553784788, states[0] = -94.122641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561959264, states[0] = -94.114953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570220131, states[0] = -93.475617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579509726, states[0] = -94.098850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588172668, states[0] = -53.890599, states[40]= 0.000140
Saving checkpoint... 
Iteration: 598116913, states[0] = -8.679978, states[40]= 0.002768
Saving checkpoint... 
Iteration: 607549433, states[0] = -94.109431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616430771, states[0] = -94.058465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625601191, states[0] = -94.117681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635172840, states[0] = -54.040783, states[40]= 0.000137
Saving checkpoint... 
Iteration: 643843275, states[0] = -94.120106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651762520, states[0] = -94.122673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660359007, states[0] = -93.980976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668600963, states[0] = -94.117432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678237236, states[0] = -93.618625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686821296, states[0] = -94.120751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697094546, states[0] = 5.659016, states[40]= 0.002937
Saving checkpoint... 
Iteration: 705125325, states[0] = -15.725213, states[40]= 0.001767
Saving checkpoint... 
Iteration: 713414843, states[0] = -94.045246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722380688, states[0] = -94.010076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731173609, states[0] = -54.714269, states[40]= 0.000124
Saving checkpoint... 
Iteration: 740593335, states[0] = -94.116138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748724406, states[0] = -94.122636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757459172, states[0] = -94.075959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767018182, states[0] = 32.597396, states[40]= 0.003580
Saving checkpoint... 
Iteration: 775612071, states[0] = -94.118060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785527459, states[0] = -94.103143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794224054, states[0] = -93.534448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803530100, states[0] = -94.103765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812953982, states[0] = -94.113927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821699669, states[0] = -94.122161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830734695, states[0] = -94.122152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839489912, states[0] = -94.090210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848724632, states[0] = -94.122118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858354509, states[0] = -93.972985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867208080, states[0] = -91.740235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877638984, states[0] = -94.119704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887157206, states[0] = -40.766572, states[40]= 0.000842
Saving checkpoint... 
Iteration: 895289419, states[0] = -93.826024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904401497, states[0] = -94.031933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914038544, states[0] = 28.208511, states[40]= 0.000149
Saving checkpoint... 
Iteration: 923198711, states[0] = -82.129344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932566417, states[0] = -94.111075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941764356, states[0] = -94.121133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950404401, states[0] = -94.034515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959958427, states[0] = -94.112934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969326542, states[0] = -93.921152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978889953, states[0] = -94.116275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987959219, states[0] = -94.112748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997650016, states[0] = -94.119727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007279471, states[0] = -93.793000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016719434, states[0] = -94.121258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025384238, states[0] = -94.012732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033852189, states[0] = -94.117709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041992101, states[0] = -94.110743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052949826, states[0] = -94.112898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061049174, states[0] = 24.609494, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1069635902, states[0] = -94.118506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078173154, states[0] = -54.312167, states[40]= 0.000132
Saving checkpoint... 
Iteration: 1086310077, states[0] = -93.882666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094459148, states[0] = -94.074196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102529163, states[0] = -94.101964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112062486, states[0] = 19.615848, states[40]= 0.000650
Saving checkpoint... 
Iteration: 1119546982, states[0] = -94.106242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128882536, states[0] = -94.115849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138560512, states[0] = -94.108924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148254844, states[0] = -93.697135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155786275, states[0] = -94.119481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164693460, states[0] = -94.120300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173716629, states[0] = -94.120444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182336996, states[0] = -93.940940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191459400, states[0] = -94.073833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200228291, states[0] = -93.566917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208329855, states[0] = -93.926771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218191064, states[0] = -71.784944, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1227984011, states[0] = -94.110205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238612982, states[0] = -94.115751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246790993, states[0] = -94.118873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255788022, states[0] = -94.118913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263495965, states[0] = -94.090399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272565340, states[0] = -94.109122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281220648, states[0] = -93.482446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290073933, states[0] = 15.009331, states[40]= 0.001229
Saving checkpoint... 
Iteration: 1298700895, states[0] = -94.119704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309915438, states[0] = -94.113315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320067448, states[0] = 17.655532, states[40]= 0.000865
Saving checkpoint... 
Iteration: 1329352649, states[0] = -93.967554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338263267, states[0] = -93.731109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346980124, states[0] = -94.109793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354872916, states[0] = -94.115125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364483518, states[0] = -94.084798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373842314, states[0] = -94.116364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383003017, states[0] = 40.129454, states[40]= 0.671088
Saving checkpoint... 
Iteration: 1392104980, states[0] = -0.140051, states[40]= 0.003590
Saving checkpoint... 
Iteration: 1402329005, states[0] = -93.924015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411199635, states[0] = -83.442558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419184016, states[0] = -64.218726, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1427483423, states[0] = -94.084430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437234097, states[0] = -93.598762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447284472, states[0] = -93.807394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455938378, states[0] = -94.111399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465757804, states[0] = -94.118549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474267065, states[0] = -93.745329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483417734, states[0] = -94.043703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491305650, states[0] = -93.869201, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.983890
 - CaMKt in component CaMK (millimolar): 0.006020
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.936085
 - nass in component intracellular_ions (millimolar): 6.936207
 - ki in component intracellular_ions (millimolar): 144.889374
 - kss in component intracellular_ions (millimolar): 144.889360
 - cansr in component intracellular_ions (millimolar): 1.895026
 - cajsr in component intracellular_ions (millimolar): 1.894046
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.003970
 - hf in component INa (dimensionless): 0.863137
 - hs in component INa (dimensionless): 0.863140
 - j in component INa (dimensionless): 0.863152
 - hsp in component INa (dimensionless): 0.694857
 - jp in component INa (dimensionless): 0.863159
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704182
 - hLp in component INaL (dimensionless): 0.491506
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.885532
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.925255
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.970593
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005022
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.111776
 - xs1 in component IKs (dimensionless): 0.137537
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997568
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:01:41 (12220): called boinc_finish(0)

</stderr_txt>
]]>


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