𝕏

Task 54932267

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-TESZT_Block_Ks_95-conf_756_2
Workunit 25855038
Created 27 Jun 2024, 9:57:51 UTC
Sent 27 Jun 2024, 9:57:56 UTC
Report deadline 30 Jun 2024, 9:57:56 UTC
Received 29 Jun 2024, 14:30:37 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 8 min 20 sec
CPU time 2 hours 21 min 16 sec
Validate state Valid
Credit 43.79
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.14 MB
Peak swap size 6.18 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-TESZT_Block_Ks_95-conf_756.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-TESZT_Block_Ks_95-conf_756_2_r905163559_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-TESZT_Block_Ks_95-conf_756_2_r905163559_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.059946
     * GNaL_b in INaL: 0.007985
     * Gto_b in Ito: 0.089718
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033798
     * GKs_b in IKs: 0.000090
     * GK1_b in IK1: 0.170875
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 68.973116
     * GKb_b in IKb: 0.003849
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033102
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9490524, states[0] = -94.963071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 19610880, states[0] = -17.598173, states[40]= 0.001481
Saving checkpoint... 
Iteration: 29709821, states[0] = -94.557387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37388332, states[0] = -94.873908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45933836, states[0] = -94.894555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53670578, states[0] = -84.245343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 61338215, states[0] = -94.831122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69922604, states[0] = -94.889147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78413436, states[0] = -94.884970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87368052, states[0] = -94.857498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96169329, states[0] = -82.067669, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104019452, states[0] = 27.563530, states[40]= 0.002872
Saving checkpoint... 
Iteration: 112156791, states[0] = -63.286996, states[40]= 0.000014
Saving checkpoint... 
Iteration: 120761118, states[0] = -94.706532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130631032, states[0] = -35.598650, states[40]= 0.000755
Saving checkpoint... 
Iteration: 138420485, states[0] = -94.888096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146058579, states[0] = 15.601620, states[40]= 0.003078
Saving checkpoint... 
Iteration: 155530148, states[0] = 25.351566, states[40]= 0.001278
Saving checkpoint... 
Iteration: 163761256, states[0] = -94.706716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172996846, states[0] = -94.911254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181421051, states[0] = -94.888181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190486347, states[0] = -94.908984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199765148, states[0] = -94.715658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208405186, states[0] = -94.880495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217437338, states[0] = -94.894617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226864477, states[0] = -94.854278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236227899, states[0] = -94.610582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245159285, states[0] = -66.464501, states[40]= 0.000008
Saving checkpoint... 
Iteration: 253044048, states[0] = 20.944350, states[40]= 0.001944
Saving checkpoint... 
Iteration: 260630599, states[0] = -35.193690, states[40]= 0.000788
Saving checkpoint... 
Iteration: 269874924, states[0] = -94.861873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278673480, states[0] = -88.691483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287846008, states[0] = -94.837995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297425662, states[0] = -94.889652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306242974, states[0] = -94.657789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313393513, states[0] = -94.873618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322084852, states[0] = 3.322025, states[40]= 0.004728
Saving checkpoint... 
Iteration: 330651038, states[0] = -56.502222, states[40]= 0.000043
Saving checkpoint... 
Iteration: 339940661, states[0] = -94.895287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349629015, states[0] = -33.713032, states[40]= 0.000911
Saving checkpoint... 
Iteration: 358222226, states[0] = -94.590225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367834043, states[0] = -94.825480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375544786, states[0] = 20.687892, states[40]= 0.001993
Saving checkpoint... 
Iteration: 384210010, states[0] = -94.543962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393413227, states[0] = -94.883663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402815373, states[0] = -94.802986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412297554, states[0] = -94.777009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421437979, states[0] = -94.893946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429927387, states[0] = -94.889776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437779189, states[0] = -94.744331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447057684, states[0] = 15.950451, states[40]= 0.003001
Saving checkpoint... 
Iteration: 456774348, states[0] = -94.734508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465817822, states[0] = -94.805893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475084787, states[0] = 3.359759, states[40]= 0.004728
Saving checkpoint... 
Iteration: 484897102, states[0] = -94.874904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492186167, states[0] = -94.310692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502466683, states[0] = -94.902745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510512425, states[0] = 27.787494, states[40]= 0.022557
Saving checkpoint... 
Iteration: 518715885, states[0] = -94.566127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528665680, states[0] = -75.815475, states[40]= 0.000002
Saving checkpoint... 
Iteration: 538685998, states[0] = -94.302289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547784865, states[0] = -94.754610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556316998, states[0] = -94.804423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565691782, states[0] = -94.446044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574397538, states[0] = -94.874748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582787595, states[0] = -94.759400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591550480, states[0] = 18.657295, states[40]= 0.002408
Saving checkpoint... 
Iteration: 598847541, states[0] = -94.838050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608495583, states[0] = -94.909070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617373317, states[0] = -94.859173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626038524, states[0] = 22.809136, states[40]= 0.001615
Saving checkpoint... 
Iteration: 634985381, states[0] = -94.906790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643198712, states[0] = -94.494477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652010042, states[0] = 27.676074, states[40]= 0.049918
Saving checkpoint... 
Iteration: 659589416, states[0] = 0.554945, states[40]= 0.004652
Saving checkpoint... 
Iteration: 669190038, states[0] = -94.421583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678546433, states[0] = 20.110040, states[40]= 0.002107
Saving checkpoint... 
Iteration: 687674722, states[0] = -90.165229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697322184, states[0] = -94.810333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705165506, states[0] = -75.528902, states[40]= 0.000002
Saving checkpoint... 
Iteration: 712543106, states[0] = 21.270138, states[40]= 0.001883
Saving checkpoint... 
Iteration: 721741121, states[0] = -94.650461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730867788, states[0] = -94.854581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739137281, states[0] = -41.665204, states[40]= 0.000368
Saving checkpoint... 
Iteration: 747988461, states[0] = -94.906963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756201499, states[0] = -94.506930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765613134, states[0] = -19.223122, states[40]= 0.001450
Saving checkpoint... 
Iteration: 775750975, states[0] = -94.677994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785558540, states[0] = 15.617301, states[40]= 0.003075
Saving checkpoint... 
Iteration: 792866730, states[0] = -94.853495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801117275, states[0] = -23.011122, states[40]= 0.001415
Saving checkpoint... 
Iteration: 810962668, states[0] = -94.900243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820690911, states[0] = -94.434038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829898504, states[0] = -94.874142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838521453, states[0] = 27.287343, states[40]= 0.001945
Saving checkpoint... 
Iteration: 846958698, states[0] = -94.898925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855230403, states[0] = -94.616185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864709181, states[0] = -94.538478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874270090, states[0] = -94.723621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883032572, states[0] = 24.664544, states[40]= 0.001347
Saving checkpoint... 
Iteration: 892628910, states[0] = -33.613377, states[40]= 0.000919
Saving checkpoint... 
Iteration: 901927692, states[0] = -94.887790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911517619, states[0] = 27.740276, states[40]= 0.004549
Saving checkpoint... 
Iteration: 920309422, states[0] = -94.792549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929955788, states[0] = -94.897675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939106196, states[0] = -12.782963, states[40]= 0.002154
Saving checkpoint... 
Iteration: 947981735, states[0] = -94.904558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956459900, states[0] = -94.898791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965621608, states[0] = -26.933133, states[40]= 0.001378
Saving checkpoint... 
Iteration: 975769498, states[0] = -94.721877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984372674, states[0] = -94.857066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992687540, states[0] = -94.361783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002253197, states[0] = -94.682836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012357448, states[0] = -94.845026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021290433, states[0] = -94.762415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030497992, states[0] = -94.907660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039494200, states[0] = -94.906865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048424039, states[0] = -94.885606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057563798, states[0] = 13.500178, states[40]= 0.003525
Saving checkpoint... 
Iteration: 1065815699, states[0] = -94.800438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074242840, states[0] = -94.653926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082431001, states[0] = -94.888318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091028511, states[0] = 25.787577, states[40]= 0.001256
Saving checkpoint... 
Iteration: 1100211195, states[0] = -94.545391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108859080, states[0] = -94.845962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117841478, states[0] = -94.829849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127304571, states[0] = -94.784609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136968148, states[0] = -94.900306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146665609, states[0] = -75.691039, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1154063624, states[0] = 13.572383, states[40]= 0.003511
Saving checkpoint... 
Iteration: 1162735775, states[0] = -94.632134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172245712, states[0] = -94.661732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182059947, states[0] = 15.063064, states[40]= 0.003196
Saving checkpoint... 
Iteration: 1190489976, states[0] = -94.905311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1199620680, states[0] = -26.092584, states[40]= 0.001400
Saving checkpoint... 
Iteration: 1207992403, states[0] = -94.905743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217382013, states[0] = -94.862454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226755615, states[0] = -94.688045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236285372, states[0] = -94.752441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246486884, states[0] = -94.904390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253366281, states[0] = -94.851086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261727438, states[0] = -94.604367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268679172, states[0] = -93.200412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276665468, states[0] = -75.459511, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1284168561, states[0] = -80.720406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294076891, states[0] = 7.577396, states[40]= 0.004472
Saving checkpoint... 
Iteration: 1303404292, states[0] = -94.875135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312621541, states[0] = -26.871240, states[40]= 0.001380
Saving checkpoint... 
Iteration: 1321113239, states[0] = -19.317984, states[40]= 0.001447
Saving checkpoint... 
Iteration: 1330401244, states[0] = -94.873398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338814068, states[0] = -94.797047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346992522, states[0] = -94.905146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356276176, states[0] = -94.734194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365804516, states[0] = -94.783456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374548811, states[0] = 19.262895, states[40]= 0.002280
Saving checkpoint... 
Iteration: 1383833566, states[0] = -94.820404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392881220, states[0] = -94.861146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403480644, states[0] = -94.902266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411730826, states[0] = -94.615064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421195250, states[0] = -94.471568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430723573, states[0] = -94.590161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439028142, states[0] = 25.882392, states[40]= 0.001255
Saving checkpoint... 
Iteration: 1448451670, states[0] = -94.894065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457587130, states[0] = 1.979163, states[40]= 0.004718
Saving checkpoint... 
Iteration: 1466274953, states[0] = -94.731205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473805055, states[0] = -94.783768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482395635, states[0] = -94.869608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492263216, states[0] = -94.705369, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.781825
 - CaMKt in component CaMK (millimolar): 0.013580
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.842362
 - nass in component intracellular_ions (millimolar): 6.842461
 - ki in component intracellular_ions (millimolar): 145.025551
 - kss in component intracellular_ions (millimolar): 145.025529
 - cansr in component intracellular_ions (millimolar): 1.712274
 - cajsr in component intracellular_ions (millimolar): 1.669705
 - cai in component intracellular_ions (millimolar): 0.000091
 - m in component INa (dimensionless): 0.003663
 - hf in component INa (dimensionless): 0.877902
 - hs in component INa (dimensionless): 0.877895
 - j in component INa (dimensionless): 0.877845
 - hsp in component INa (dimensionless): 0.721870
 - jp in component INa (dimensionless): 0.877811
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.702829
 - hLp in component INaL (dimensionless): 0.437679
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.604942
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.674790
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.909574
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999803
 - jca in component ICaL (dimensionless): 0.999968
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003312
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.373392
 - xs1 in component IKs (dimensionless): 0.280108
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997369
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:30:25 (10476): called boinc_finish(0)

</stderr_txt>
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