𝕏

Task 54932235

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_4000-conf_356_2
Workunit 25854803
Created 27 Jun 2024, 9:57:51 UTC
Sent 27 Jun 2024, 9:57:56 UTC
Report deadline 30 Jun 2024, 9:57:56 UTC
Received 29 Jun 2024, 22:18:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 5 min 49 sec
CPU time 2 hours 20 min 39 sec
Validate state Valid
Credit 41.79
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.17 MB
Peak swap size 6.25 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_4000-conf_356.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_4000-conf_356_2_r216183517_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_4000-conf_356_2_r216183517_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 123.612636
     * GNaL_b in INaL: 0.007421
     * Gto_b in Ito: 0.080901
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031877
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.165711
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 64.566828
     * GKb_b in IKb: 0.003886
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.051996
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8534321, states[0] = -94.272012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18475548, states[0] = -43.359941, states[40]= 0.001820
Saving checkpoint... 
Iteration: 27805387, states[0] = -94.270503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 36842118, states[0] = -94.309813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45891731, states[0] = -94.286341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 54128719, states[0] = 7.005111, states[40]= 0.000125
Saving checkpoint... 
Iteration: 62291106, states[0] = -81.311930, states[40]= 0.000006
Saving checkpoint... 
Iteration: 70877872, states[0] = -94.343237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 80696904, states[0] = -94.342133, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90303153, states[0] = -93.778426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100445682, states[0] = -94.226836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108110931, states[0] = 12.117751, states[40]= 0.000033
Saving checkpoint... 
Iteration: 117301359, states[0] = -94.344556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125628336, states[0] = -94.337168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 133570747, states[0] = -94.339435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143056501, states[0] = -94.355882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151492764, states[0] = -94.342907, states[40]= 0.000001
Saving checkpoint... 
Iteration: 160435613, states[0] = -94.224632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169408928, states[0] = -94.346097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180135927, states[0] = 2.497108, states[40]= 0.000252
Saving checkpoint... 
Iteration: 189593254, states[0] = -94.342054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198788434, states[0] = -94.362827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208012076, states[0] = 30.785523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218325855, states[0] = -93.941738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227999769, states[0] = -94.335345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237351028, states[0] = -94.348708, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246117984, states[0] = 9.129462, states[40]= 0.000065
Saving checkpoint... 
Iteration: 255752507, states[0] = -94.339119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265434257, states[0] = -94.346231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274449374, states[0] = -94.244738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284058806, states[0] = 29.866596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292963039, states[0] = -94.360988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301135486, states[0] = -94.355299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311165863, states[0] = -94.354167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320806927, states[0] = -94.362741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330116274, states[0] = 9.748254, states[40]= 0.000057
Saving checkpoint... 
Iteration: 339126928, states[0] = -94.355224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348011651, states[0] = 30.558023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356467842, states[0] = -94.264541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364135603, states[0] = 2.525693, states[40]= 0.000249
Saving checkpoint... 
Iteration: 372495285, states[0] = -94.288776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380358679, states[0] = -94.062420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389622163, states[0] = -94.340483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399425112, states[0] = -94.345197, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408289923, states[0] = -93.614789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417203520, states[0] = -94.351791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426190770, states[0] = -22.473604, states[40]= 0.005532
Saving checkpoint... 
Iteration: 434604883, states[0] = -94.340545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 443743777, states[0] = -94.337462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451332263, states[0] = -94.347308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460675057, states[0] = -94.353568, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469371713, states[0] = -94.345942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477453444, states[0] = -94.343583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486094539, states[0] = 17.767967, states[40]= 0.000008
Saving checkpoint... 
Iteration: 497287401, states[0] = -94.348188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506789582, states[0] = -94.360481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515643565, states[0] = -94.338652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524948049, states[0] = -94.358946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528459049, states[0] = -94.253358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 537713926, states[0] = -94.336994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546532547, states[0] = -94.311162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555620665, states[0] = -94.338703, states[40]= 0.000001
Saving checkpoint... 
Iteration: 565035198, states[0] = -94.355888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573198754, states[0] = -94.350245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582197692, states[0] = -24.530445, states[40]= 0.006798
Saving checkpoint... 
Iteration: 590972986, states[0] = -94.357537, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597946274, states[0] = -94.332500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605544056, states[0] = -94.339897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614415759, states[0] = -94.192586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622851933, states[0] = -94.359570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631375327, states[0] = -94.344061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640140659, states[0] = 0.533353, states[40]= 0.000345
Saving checkpoint... 
Iteration: 649340636, states[0] = -94.344886, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657862986, states[0] = -94.333079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666092004, states[0] = 18.696996, states[40]= 0.000006
Saving checkpoint... 
Iteration: 674432604, states[0] = -94.218326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683761072, states[0] = -94.334513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692895919, states[0] = -94.358263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 702191718, states[0] = -22.751638, states[40]= 0.005756
Saving checkpoint... 
Iteration: 711299737, states[0] = -94.345455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721273884, states[0] = -94.346160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731074741, states[0] = -94.352744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 739625956, states[0] = -94.336569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748670822, states[0] = -94.349863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757323127, states[0] = -94.344231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766022051, states[0] = 33.698425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775373300, states[0] = -94.342541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783945029, states[0] = -94.330477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 792701500, states[0] = -94.352803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 801228599, states[0] = -94.346753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811927295, states[0] = -94.330422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 821699540, states[0] = -94.334159, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830435192, states[0] = -94.220274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839556700, states[0] = -94.337032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849165518, states[0] = -94.348344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858409318, states[0] = -94.178527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866433794, states[0] = -94.217903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874903188, states[0] = -94.356138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883447088, states[0] = -94.339301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 892035431, states[0] = 34.181891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901732064, states[0] = -94.332657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909196065, states[0] = -94.346653, states[40]= 0.000001
Saving checkpoint... 
Iteration: 917559759, states[0] = -94.336105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925910501, states[0] = -94.329415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936003508, states[0] = 20.950104, states[40]= 0.952844
Saving checkpoint... 
Iteration: 946465921, states[0] = -94.256090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955044169, states[0] = -94.351319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963503030, states[0] = -94.336974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972492887, states[0] = -94.280300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980388055, states[0] = -94.133854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989037982, states[0] = -94.351151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998739248, states[0] = -94.353275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007957178, states[0] = -94.327850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1016077223, states[0] = 23.987204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025470089, states[0] = -94.337137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034112911, states[0] = 10.991553, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1042624028, states[0] = -94.338527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1052077348, states[0] = 23.943935, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1061653056, states[0] = -94.332463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1071550768, states[0] = -94.334626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080396094, states[0] = -94.150249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089322770, states[0] = -94.340602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097750955, states[0] = -94.330155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1107556974, states[0] = -94.334086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117372245, states[0] = -94.338823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1126620840, states[0] = -94.336893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1135091401, states[0] = -94.347750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1143637116, states[0] = -94.331899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151846109, states[0] = -94.327926, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160236505, states[0] = -43.161447, states[40]= 0.001693
Saving checkpoint... 
Iteration: 1169615162, states[0] = -94.332086, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178720736, states[0] = -94.350139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1187525348, states[0] = -94.333964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196866388, states[0] = -94.353162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205683470, states[0] = -94.330263, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214518308, states[0] = -94.295545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1223148985, states[0] = -94.344810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1231651649, states[0] = -94.330628, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1240380057, states[0] = -94.112015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249876679, states[0] = -94.326370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1259581803, states[0] = -94.331845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269355863, states[0] = -94.337636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1277175616, states[0] = -94.343311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1285938444, states[0] = -94.325061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1294942642, states[0] = -94.350651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305640506, states[0] = -94.330051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314886643, states[0] = -94.351605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324606311, states[0] = -94.331163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1334177816, states[0] = -17.959749, states[40]= 0.001917
Saving checkpoint... 
Iteration: 1344759276, states[0] = -94.350418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1354202814, states[0] = -26.135001, states[40]= 0.007178
Saving checkpoint... 
Iteration: 1364624626, states[0] = -94.335128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1373981304, states[0] = -94.323506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1384108982, states[0] = 12.443726, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1393053137, states[0] = -94.346221, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1401489483, states[0] = -94.332513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410580730, states[0] = -94.322543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1419389503, states[0] = -94.335014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428309688, states[0] = -93.853383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437410925, states[0] = -94.334213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445557762, states[0] = -94.330360, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455200976, states[0] = -94.340504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464757928, states[0] = -94.349051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473790266, states[0] = -94.325330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482430612, states[0] = -94.206489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492253127, states[0] = -55.735738, states[40]= 0.000289
Saving checkpoint... 
Iteration: 1499761287, states[0] = -94.325557, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.197846
 - CaMKt in component CaMK (millimolar): 0.002706
 - cass in component intracellular_ions (millimolar): 0.000098
 - nai in component intracellular_ions (millimolar): 7.964681
 - nass in component intracellular_ions (millimolar): 7.964841
 - ki in component intracellular_ions (millimolar): 143.821581
 - kss in component intracellular_ions (millimolar): 143.821564
 - cansr in component intracellular_ions (millimolar): 1.856364
 - cajsr in component intracellular_ions (millimolar): 1.858044
 - cai in component intracellular_ions (millimolar): 0.000103
 - m in component INa (dimensionless): 0.003885
 - hf in component INa (dimensionless): 0.867237
 - hs in component INa (dimensionless): 0.867237
 - j in component INa (dimensionless): 0.867241
 - hsp in component INa (dimensionless): 0.702249
 - jp in component INa (dimensionless): 0.867242
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.710240
 - hLp in component INaL (dimensionless): 0.516236
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999853
 - iS in component Ito (dimensionless): 0.990007
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999853
 - iSp in component Ito (dimensionless): 0.995914
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994617
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004708
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009116
 - xs1 in component IKs (dimensionless): 0.055097
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997516
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
00:16:38 (6580): called boinc_finish(0)

</stderr_txt>
]]>


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