𝕏

Task 54932234

Name HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_3000-conf_856_2
Workunit 25854799
Created 27 Jun 2024, 9:57:51 UTC
Sent 27 Jun 2024, 9:57:56 UTC
Report deadline 30 Jun 2024, 9:57:56 UTC
Received 29 Jun 2024, 15:47:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214250
Run time 3 hours 5 min 48 sec
CPU time 2 hours 20 min 45 sec
Validate state Valid
Credit 41.22
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.23 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_3000-conf_856.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_3000-conf_856_2_r1276305121_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240624175735641681_ORdGradInc_k_24-Drouin_MID_3000-conf_856_2_r1276305121_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.676696
     * GNaL_b in INaL: 0.008539
     * Gto_b in Ito: 0.083603
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033888
     * GKs_b in IKs: 0.001780
     * GK1_b in IK1: 0.144902
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 63.521568
     * GKb_b in IKb: 0.003876
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034987
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8036108, states[0] = -94.033663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16748866, states[0] = -33.119821, states[40]= 0.005438
Saving checkpoint... 
Iteration: 24936506, states[0] = -94.073524, states[40]= 0.000001
Saving checkpoint... 
Iteration: 32698503, states[0] = -94.069994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 41668229, states[0] = -94.083756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 50746511, states[0] = -94.092101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59761836, states[0] = -94.102189, states[40]= 0.000001
Saving checkpoint... 
Iteration: 70027889, states[0] = -94.124143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79995617, states[0] = -94.058670, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89723943, states[0] = -94.129338, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98751530, states[0] = -94.132984, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107061792, states[0] = -94.118874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 116316031, states[0] = -94.158532, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125869749, states[0] = -94.137552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135053013, states[0] = 31.218511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143265076, states[0] = -94.164372, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151099392, states[0] = -94.154543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 159529551, states[0] = -94.114228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166715917, states[0] = -37.046174, states[40]= 0.004131
Saving checkpoint... 
Iteration: 174391838, states[0] = -93.932885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182271962, states[0] = -94.168080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192259092, states[0] = -71.587843, states[40]= 0.000032
Saving checkpoint... 
Iteration: 199923522, states[0] = -94.001016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208678338, states[0] = -21.071671, states[40]= 0.004640
Saving checkpoint... 
Iteration: 218404604, states[0] = -94.166858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227991586, states[0] = -94.140794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 236699711, states[0] = -94.152904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244713145, states[0] = -35.866596, states[40]= 0.004641
Saving checkpoint... 
Iteration: 254814845, states[0] = -94.147549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 262838536, states[0] = -93.757947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270720626, states[0] = -94.166660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 279133461, states[0] = 1.822304, states[40]= 0.000435
Saving checkpoint... 
Iteration: 287607252, states[0] = -94.156858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295771703, states[0] = -89.448113, states[40]= 0.000002
Saving checkpoint... 
Iteration: 304562919, states[0] = 28.331179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313317331, states[0] = -94.146572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 323008000, states[0] = -94.101102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333028226, states[0] = 34.134579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342574860, states[0] = -94.137699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352223038, states[0] = -94.150078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361549325, states[0] = 31.955533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370812036, states[0] = -93.623334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381243260, states[0] = -57.368819, states[40]= 0.000286
Saving checkpoint... 
Iteration: 390185245, states[0] = -23.688641, states[40]= 0.006938
Saving checkpoint... 
Iteration: 399078217, states[0] = 23.192153, states[40]= 0.000003
Saving checkpoint... 
Iteration: 407839375, states[0] = -94.143816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416747466, states[0] = -94.147672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 425467325, states[0] = -94.161084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434349356, states[0] = -94.165175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 442534120, states[0] = 34.078898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450308953, states[0] = -93.603807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458818651, states[0] = -94.143674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 468500314, states[0] = -94.092180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477338992, states[0] = -93.756013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487438782, states[0] = -94.138275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496710639, states[0] = -34.517317, states[40]= 0.005270
Saving checkpoint... 
Iteration: 506076556, states[0] = -94.135097, states[40]= 0.000001
Saving checkpoint... 
Iteration: 517195479, states[0] = -94.148090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525364602, states[0] = -93.852114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534659078, states[0] = -94.155293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545176842, states[0] = -94.157491, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554840066, states[0] = -94.140834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 563956387, states[0] = -94.136083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573051401, states[0] = 31.487491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581107117, states[0] = -94.143523, states[40]= 0.000001
Saving checkpoint... 
Iteration: 591460930, states[0] = -94.050216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 601501240, states[0] = 40.532778, states[40]= 2.197238
Saving checkpoint... 
Iteration: 611508090, states[0] = -94.155429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 621581388, states[0] = -94.134561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628259451, states[0] = -94.142877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636328589, states[0] = -93.705045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644704916, states[0] = -94.145076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653829969, states[0] = -94.139267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662403500, states[0] = -94.158974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 671528004, states[0] = -94.153253, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680687558, states[0] = -94.145182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 690342479, states[0] = -93.766446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699394071, states[0] = -93.931835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 708469082, states[0] = -94.057343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717807198, states[0] = -94.160065, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727980043, states[0] = -94.068548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736229706, states[0] = -94.142069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744468861, states[0] = -94.056362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752885370, states[0] = -94.135000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760786167, states[0] = -93.396880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770922629, states[0] = -94.133181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778979064, states[0] = -94.066530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788352508, states[0] = -94.157993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797453951, states[0] = -94.154214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 805419526, states[0] = -94.132613, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814456951, states[0] = -94.131029, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822591281, states[0] = -94.133924, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831375237, states[0] = -93.878979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840328691, states[0] = -93.701348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849180729, states[0] = -22.046994, states[40]= 0.005560
Saving checkpoint... 
Iteration: 859185784, states[0] = -94.141686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 869437940, states[0] = -94.153462, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878336742, states[0] = -94.156515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887869731, states[0] = -94.132920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 897728704, states[0] = -94.154792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 908051655, states[0] = -94.116226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918319393, states[0] = -93.652560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927302846, states[0] = -93.556740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935608295, states[0] = -94.143953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 943884160, states[0] = -93.901704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954649816, states[0] = -94.145370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965925103, states[0] = -94.129170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 974421465, states[0] = -94.152026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983193862, states[0] = -94.150520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990874840, states[0] = -94.153334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1000059605, states[0] = -94.145088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1008015600, states[0] = 32.176538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016344504, states[0] = -94.153592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024914018, states[0] = -93.968579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032397111, states[0] = -93.932266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042053316, states[0] = -94.144557, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051443142, states[0] = -94.126767, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059373089, states[0] = -93.867910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1068368846, states[0] = -93.854659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075882412, states[0] = -93.894281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084253105, states[0] = -94.133997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091877296, states[0] = -94.128505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099957102, states[0] = -94.035193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1108444569, states[0] = -94.125565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117028880, states[0] = -94.144257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124725923, states[0] = -94.134437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1134443298, states[0] = -94.015819, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144389900, states[0] = -94.126944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154351220, states[0] = -94.150672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1162879159, states[0] = -93.883481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1171906953, states[0] = -93.951244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1180955815, states[0] = -94.031919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190621441, states[0] = -94.138167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199965111, states[0] = -94.122966, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208597279, states[0] = -94.139011, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218698492, states[0] = -94.146211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1229645896, states[0] = -94.136172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239602682, states[0] = -94.129025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247422358, states[0] = -94.146502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255864977, states[0] = -93.838367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264591725, states[0] = 18.217725, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1273720433, states[0] = -40.408300, states[40]= 0.002850
Saving checkpoint... 
Iteration: 1282735131, states[0] = -51.027907, states[40]= 0.000728
Saving checkpoint... 
Iteration: 1290443586, states[0] = -94.013072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300265286, states[0] = -94.129098, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310964258, states[0] = -94.120764, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319246339, states[0] = -94.147109, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1329124747, states[0] = 5.400651, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1337685090, states[0] = -94.132094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346155681, states[0] = -94.138465, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355605203, states[0] = -94.135667, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363237964, states[0] = -94.129091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372950593, states[0] = -94.021195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380350298, states[0] = -93.783623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388772638, states[0] = -94.126997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398912184, states[0] = -94.143864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1407516267, states[0] = -94.085325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417053517, states[0] = -94.137014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424040843, states[0] = -94.100235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1432655880, states[0] = -9.312956, states[40]= 0.001054
Saving checkpoint... 
Iteration: 1440937698, states[0] = -94.141991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1451038548, states[0] = -94.098416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1460668846, states[0] = -94.130412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1469902005, states[0] = -94.119925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1480771696, states[0] = -89.356164, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1490973895, states[0] = -94.116799, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.991653
 - CaMKt in component CaMK (millimolar): 0.004698
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 8.156089
 - nass in component intracellular_ions (millimolar): 8.156257
 - ki in component intracellular_ions (millimolar): 143.537736
 - kss in component intracellular_ions (millimolar): 143.537716
 - cansr in component intracellular_ions (millimolar): 1.971711
 - cajsr in component intracellular_ions (millimolar): 1.974163
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003967
 - hf in component INa (dimensionless): 0.863288
 - hs in component INa (dimensionless): 0.863289
 - j in component INa (dimensionless): 0.863298
 - hsp in component INa (dimensionless): 0.695122
 - jp in component INa (dimensionless): 0.863302
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704604
 - hLp in component INaL (dimensionless): 0.505381
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.963532
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.980806
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985512
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005221
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.035029
 - xs1 in component IKs (dimensionless): 0.094129
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997566
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:47:44 (84): called boinc_finish(0)

</stderr_txt>
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