𝕏

Task 54932113

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3
Workunit 26009634
Created 27 Jun 2024, 9:43:54 UTC
Sent 27 Jun 2024, 9:43:56 UTC
Report deadline 30 Jun 2024, 9:43:56 UTC
Received 27 Jun 2024, 22:33:18 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 1 hours 56 min 3 sec
CPU time 1 hours 50 min 49 sec
Validate state Checked, but no consensus yet
Credit 0.00
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.87 MB
Peak swap size 32.57 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 109.127018
     * GNaL_b in INaL: 0.007162
     * Gto_b in Ito: 0.070362
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033192
     * GKs_b in IKs: 0.001853
     * GK1_b in IK1: 0.164652
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 64.607661
     * GKb_b in IKb: 0.003823
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13584032, states[0] = 17.084231, states[40]= 0.000001
Saving checkpoint... 
Iteration: 27115779, states[0] = 1.881281, states[40]= 0.000044
Saving checkpoint... 
Iteration: 40535734, states[0] = 32.102616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54075994, states[0] = 18.151884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67572679, states[0] = 19.197217, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81099237, states[0] = 6.844531, states[40]= 0.000026
Saving checkpoint... 
Iteration: 94479939, states[0] = -87.042318, states[40]= 0.000002
Saving checkpoint... 
Iteration: 108054266, states[0] = 25.887323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121528645, states[0] = 32.446573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135003376, states[0] = 19.684416, states[40]= 1.065808
Saving checkpoint... 
Iteration: 148572818, states[0] = 18.472570, states[40]= 0.000002
Saving checkpoint... 
Iteration: 162040211, states[0] = 30.101374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175498361, states[0] = -87.059705, states[40]= 0.000002
Saving checkpoint... 
Iteration: 189038563, states[0] = 30.498024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202504719, states[0] = 21.309990, states[40]= -0.000000
Saving checkpoint... 
Iteration: 215909233, states[0] = -87.010448, states[40]= 0.000002
Saving checkpoint... 
Iteration: 229402569, states[0] = -87.004003, states[40]= 0.000002
Saving checkpoint... 
Iteration: 242835053, states[0] = -86.910025, states[40]= 0.000002
Saving checkpoint... 
Iteration: 256137637, states[0] = -21.371983, states[40]= 0.000234
Saving checkpoint... 
Iteration: 269658232, states[0] = -38.681740, states[40]= 0.000274
Saving checkpoint... 
Iteration: 283153825, states[0] = -34.683214, states[40]= 0.000362
Saving checkpoint... 
Iteration: 296855339, states[0] = -86.943395, states[40]= 0.000002
Saving checkpoint... 
Iteration: 310316928, states[0] = -86.866587, states[40]= 0.000001
Saving checkpoint... 
Iteration: 323805241, states[0] = -86.835001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337210477, states[0] = -86.321154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350722389, states[0] = -86.429059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364228517, states[0] = -86.473588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377741002, states[0] = -86.555910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391177573, states[0] = -59.153893, states[40]= 0.000027
Saving checkpoint... 
Iteration: 404578645, states[0] = 15.857160, states[40]= 0.000004
Saving checkpoint... 
Iteration: 418006397, states[0] = 25.172916, states[40]= -0.000000
Saving checkpoint... 
Iteration: 431495281, states[0] = -87.047351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 444866369, states[0] = -86.952128, states[40]= 0.000002
Saving checkpoint... 
Iteration: 458271896, states[0] = -86.711466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471723377, states[0] = -86.430186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484998367, states[0] = -87.045621, states[40]= 0.000002
Saving checkpoint... 
Iteration: 498507611, states[0] = 26.951599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512019381, states[0] = 32.646968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525531121, states[0] = 32.013374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538960352, states[0] = -87.027896, states[40]= 0.000002
Saving checkpoint... 
Iteration: 552345991, states[0] = -86.914797, states[40]= 0.000002
Saving checkpoint... 
Iteration: 564929951, states[0] = -87.009021, states[40]= 0.000002
Saving checkpoint... 
Iteration: 577670783, states[0] = -51.312978, states[40]= 0.000073
Saving checkpoint... 
Iteration: 590561958, states[0] = 22.848168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603325314, states[0] = -86.871185, states[40]= 0.000002


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 109.127018
     * GNaL_b in INaL: 0.007162
     * Gto_b in Ito: 0.070362
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033192
     * GKs_b in IKs: 0.001853
     * GK1_b in IK1: 0.164652
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 64.607661
     * GKb_b in IKb: 0.003823
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 603325314
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.871185 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 109.127018
     * GNaL_b in INaL: 0.007162
     * Gto_b in Ito: 0.070362
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033192
     * GKs_b in IKs: 0.001853
     * GK1_b in IK1: 0.164652
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 64.607661
     * GKb_b in IKb: 0.003823
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 603325314
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.871185 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 617082954, states[0] = 13.911252, states[40]= 0.000006
Saving checkpoint... 
Iteration: 630504091, states[0] = 19.929792, states[40]= 0.784862
Saving checkpoint... 
Iteration: 643898254, states[0] = -86.979089, states[40]= 0.000002
Saving checkpoint... 
Iteration: 657367174, states[0] = -86.942362, states[40]= 0.000002
Saving checkpoint... 
Iteration: 670926935, states[0] = -87.001517, states[40]= 0.000002
Saving checkpoint... 
Iteration: 684486273, states[0] = -87.031391, states[40]= 0.000002
Saving checkpoint... 
Iteration: 697998466, states[0] = -87.034804, states[40]= 0.000002
Saving checkpoint... 
Iteration: 711585329, states[0] = 12.816014, states[40]= 0.000008
Saving checkpoint... 
Iteration: 725179178, states[0] = -61.131743, states[40]= 0.000021
Saving checkpoint... 
Iteration: 738779457, states[0] = -86.727630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752376602, states[0] = -86.949795, states[40]= 0.000002
Saving checkpoint... 
Iteration: 765961355, states[0] = -87.016829, states[40]= 0.000002


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_820_3_r1362705733_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 109.127018
     * GNaL_b in INaL: 0.007162
     * Gto_b in Ito: 0.070362
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033192
     * GKs_b in IKs: 0.001853
     * GK1_b in IK1: 0.164652
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 64.607661
     * GKb_b in IKb: 0.003823
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035276
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 765961355
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -87.016829 (After loading)
 - states[40]: 0.000002 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 779709742, states[0] = -86.287016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793206089, states[0] = -86.209287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806656299, states[0] = -36.866071, states[40]= 0.000312
Saving checkpoint... 
Iteration: 820189846, states[0] = -77.375812, states[40]= 0.000002
Saving checkpoint... 
Iteration: 833867813, states[0] = -86.934177, states[40]= 0.000002
Saving checkpoint... 
Iteration: 847411242, states[0] = -86.980425, states[40]= 0.000002
Saving checkpoint... 
Iteration: 860790333, states[0] = -86.760898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874477719, states[0] = -87.018475, states[40]= 0.000002
Saving checkpoint... 
Iteration: 888082470, states[0] = 14.139422, states[40]= 0.000006
Saving checkpoint... 
Iteration: 901676740, states[0] = -58.063918, states[40]= 0.000031
Saving checkpoint... 
Iteration: 915508043, states[0] = 27.463176, states[40]= -0.000000
Saving checkpoint... 
Iteration: 929329465, states[0] = -86.863453, states[40]= 0.000002
Saving checkpoint... 
Iteration: 943071863, states[0] = 18.821585, states[40]= 0.000001
Saving checkpoint... 
Iteration: 956906868, states[0] = -86.971075, states[40]= 0.000002
Saving checkpoint... 
Iteration: 970728816, states[0] = -86.443710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984632450, states[0] = -17.027843, states[40]= 0.000158
Saving checkpoint... 
Iteration: 998345465, states[0] = -86.890966, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1012107757, states[0] = 1.443497, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1025854987, states[0] = -86.905473, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1039611568, states[0] = -0.820184, states[40]= 0.000093
Saving checkpoint... 
Iteration: 1053371971, states[0] = -86.928508, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1067144678, states[0] = -26.937056, states[40]= 0.000388
Saving checkpoint... 
Iteration: 1080961677, states[0] = -87.000933, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1094841889, states[0] = -86.879567, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1108603814, states[0] = 3.638650, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1122439121, states[0] = -86.986520, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1136268909, states[0] = -86.663196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1150011497, states[0] = 30.282449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163644610, states[0] = -26.875228, states[40]= 0.000387
Saving checkpoint... 
Iteration: 1177263674, states[0] = -86.637123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190918471, states[0] = -86.968723, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1204284293, states[0] = -86.721751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1217683510, states[0] = -67.062455, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1231250146, states[0] = -86.564833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244729198, states[0] = -86.431975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258075117, states[0] = 17.429962, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1271666331, states[0] = -46.530801, states[40]= 0.000126
Saving checkpoint... 
Iteration: 1285242555, states[0] = -86.517789, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298858546, states[0] = -86.897013, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1312556106, states[0] = 25.065203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325784014, states[0] = -86.714423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339286227, states[0] = -86.721781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352888957, states[0] = -86.933363, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1366444918, states[0] = -86.977567, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1379930038, states[0] = -86.967516, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1393524391, states[0] = 32.757874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407072244, states[0] = 18.669327, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1420732477, states[0] = -86.445523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434343320, states[0] = -86.864773, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1447938102, states[0] = -86.969326, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1461436488, states[0] = -86.967618, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1474968141, states[0] = -86.983870, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1488482471, states[0] = -86.989075, states[40]= 0.000002
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.870366
 - CaMKt in component CaMK (millimolar): 0.024879
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.171093
 - nass in component intracellular_ions (millimolar): 8.171243
 - ki in component intracellular_ions (millimolar): 143.260913
 - kss in component intracellular_ions (millimolar): 143.260875
 - cansr in component intracellular_ions (millimolar): 2.032529
 - cajsr in component intracellular_ions (millimolar): 1.965898
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008127
 - hf in component INa (dimensionless): 0.662123
 - hs in component INa (dimensionless): 0.662094
 - j in component INa (dimensionless): 0.661924
 - hsp in component INa (dimensionless): 0.414258
 - jp in component INa (dimensionless): 0.661802
 - mL in component INaL (dimensionless): 0.000228
 - hL in component INaL (dimensionless): 0.458297
 - hLp in component INaL (dimensionless): 0.223948
 - a in component Ito (dimensionless): 0.001071
 - iF in component Ito (dimensionless): 0.999468
 - iS in component Ito (dimensionless): 0.534870
 - ap in component Ito (dimensionless): 0.000546
 - iFp in component Ito (dimensionless): 0.999468
 - iSp in component Ito (dimensionless): 0.578634
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.876118
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999604
 - jca in component ICaL (dimensionless): 0.999940
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003817
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.509183
 - xs1 in component IKs (dimensionless): 0.334230
 - xs2 in component IKs (dimensionless): 0.000216
 - xk1 in component IK1 (dimensionless): 0.997014
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
14:32:44 (86341): called boinc_finish(0)

</stderr_txt>
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