𝕏

Task 54929847

Name HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_661_0
Workunit 26083124
Created 27 Jun 2024, 4:20:43 UTC
Sent 27 Jun 2024, 5:32:09 UTC
Report deadline 30 Jun 2024, 15:08:09 UTC
Received 27 Jun 2024, 12:18:38 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227241
Run time 3 hours 5 min 1 sec
CPU time 2 hours 52 min 59 sec
Validate state Valid
Credit 55.83
Device peak FLOPS 2.94 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.20 MB
Peak swap size 6.23 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_661.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_661_0_r474987417_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_661_0_r474987417_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.151196
     * GNaL_b in INaL: 0.008114
     * Gto_b in Ito: 0.085468
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.032521
     * GKs_b in IKs: 0.001915
     * GK1_b in IK1: 0.171301
     * Gncx_b in INaCa_i: 0.000952
     * Pnak_b in INaK: 69.479896
     * GKb_b in IKb: 0.004039
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049646
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12929674, states[0] = -95.305934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26365295, states[0] = -95.257861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39794373, states[0] = -95.202660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52484779, states[0] = -95.257965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65928628, states[0] = -95.241998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79337350, states[0] = -95.207446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91821513, states[0] = -95.196146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105316011, states[0] = -95.190784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117334787, states[0] = -95.199927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128721980, states[0] = -95.092754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141552807, states[0] = 11.856173, states[40]= 0.004907
Saving checkpoint... 
Iteration: 154071299, states[0] = 4.198315, states[40]= 0.004621
Saving checkpoint... 
Iteration: 166585573, states[0] = -3.659336, states[40]= 0.003618
Saving checkpoint... 
Iteration: 178874892, states[0] = -95.214185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190882355, states[0] = -95.216509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203577890, states[0] = 0.927535, states[40]= 0.004321
Saving checkpoint... 
Iteration: 216553089, states[0] = 11.776156, states[40]= 0.004904
Saving checkpoint... 
Iteration: 228756130, states[0] = -95.136366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241526814, states[0] = 20.440603, states[40]= 0.006541
Saving checkpoint... 
Iteration: 253687037, states[0] = -95.024997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266037512, states[0] = 17.311351, states[40]= 0.005303
Saving checkpoint... 
Iteration: 278284281, states[0] = -95.163634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290600099, states[0] = -15.286491, states[40]= 0.001414
Saving checkpoint... 
Iteration: 303387297, states[0] = -95.217646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316095782, states[0] = -11.469360, states[40]= 0.002017
Saving checkpoint... 
Iteration: 328245400, states[0] = -95.123470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341336745, states[0] = -95.197743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354176488, states[0] = -94.928304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366226247, states[0] = -95.096994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378930663, states[0] = -95.228500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391736738, states[0] = -95.112087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404363584, states[0] = -95.209432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417099757, states[0] = -14.977563, states[40]= 0.001454
Saving checkpoint... 
Iteration: 428702888, states[0] = -95.057606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441354647, states[0] = -95.205833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452772558, states[0] = -95.153046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465444943, states[0] = -95.231176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477765747, states[0] = -95.146353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489747700, states[0] = -95.126206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501575285, states[0] = 2.290134, states[40]= 0.004464
Saving checkpoint... 
Iteration: 513935973, states[0] = -95.229472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526960750, states[0] = -95.233768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539241475, states[0] = -95.118314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552102662, states[0] = -17.605811, states[40]= 0.001161
Saving checkpoint... 
Iteration: 564460070, states[0] = -95.233638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577551173, states[0] = 12.496818, states[40]= 0.004922
Saving checkpoint... 
Iteration: 590919469, states[0] = -95.225954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603956994, states[0] = -95.233128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616414454, states[0] = -95.224774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629211595, states[0] = -95.073058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639308812, states[0] = -95.181588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651200254, states[0] = -95.052543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662981536, states[0] = -95.236600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674942825, states[0] = -95.230660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687140917, states[0] = -55.728917, states[40]= 0.000012
Saving checkpoint... 
Iteration: 694249895, states[0] = -95.128730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705188592, states[0] = -95.028641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717883901, states[0] = -95.216313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728969045, states[0] = -95.234872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742093611, states[0] = -9.633428, states[40]= 0.002378
Saving checkpoint... 
Iteration: 754006388, states[0] = 25.873276, states[40]= 0.119279
Saving checkpoint... 
Iteration: 765143775, states[0] = -59.200598, states[40]= 0.000007
Saving checkpoint... 
Iteration: 776623491, states[0] = -36.845279, states[40]= 0.000216
Saving checkpoint... 
Iteration: 788833090, states[0] = -95.195606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801475485, states[0] = -95.235720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813301041, states[0] = -95.176189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826005501, states[0] = 27.346846, states[40]= 0.139024
Saving checkpoint... 
Iteration: 837708621, states[0] = -95.067721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848744004, states[0] = -95.121371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862423576, states[0] = -95.226695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874724624, states[0] = -95.094189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887490787, states[0] = -95.237584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899811675, states[0] = -95.183269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912009723, states[0] = 23.567161, states[40]= 0.056272
Saving checkpoint... 
Iteration: 924972797, states[0] = -95.235275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937321384, states[0] = -95.189129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950330700, states[0] = -95.194260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962028059, states[0] = 20.123894, states[40]= 0.006294
Saving checkpoint... 
Iteration: 973708035, states[0] = -95.066594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986256946, states[0] = -95.136675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998489034, states[0] = -95.237307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011469329, states[0] = -95.234734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024474521, states[0] = -95.235448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036910995, states[0] = -95.223672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049025779, states[0] = 20.694567, states[40]= 0.006788
Saving checkpoint... 
Iteration: 1062417553, states[0] = -95.225217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075448099, states[0] = -95.231345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088432604, states[0] = -95.228441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100553916, states[0] = 11.466890, states[40]= 0.004897
Saving checkpoint... 
Iteration: 1113340797, states[0] = -95.199220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124579374, states[0] = 0.126384, states[40]= 0.004222
Saving checkpoint... 
Iteration: 1136275058, states[0] = -95.154945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148912692, states[0] = -95.224014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161140162, states[0] = -54.830404, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1173604220, states[0] = -19.022594, states[40]= 0.001045
Saving checkpoint... 
Iteration: 1185036304, states[0] = 17.703531, states[40]= 0.005377
Saving checkpoint... 
Iteration: 1197914377, states[0] = -95.224387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210547740, states[0] = 13.758788, states[40]= 0.004966
Saving checkpoint... 
Iteration: 1223817190, states[0] = -95.186475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236276626, states[0] = -95.156316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249456823, states[0] = -95.232691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262418107, states[0] = -95.225217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275720068, states[0] = -95.086770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288998805, states[0] = -95.238229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301022751, states[0] = 21.369782, states[40]= 0.007838
Saving checkpoint... 
Iteration: 1312660816, states[0] = -86.042481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325032432, states[0] = 18.901071, states[40]= 0.005698
Saving checkpoint... 
Iteration: 1338669884, states[0] = -94.287248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351097255, states[0] = -12.750669, states[40]= 0.001790
Saving checkpoint... 
Iteration: 1363628561, states[0] = -41.907288, states[40]= 0.000105
Saving checkpoint... 
Iteration: 1376715354, states[0] = -95.078976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377137921, states[0] = -52.203203, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1389668432, states[0] = -93.860606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402385302, states[0] = -95.216318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415347701, states[0] = -95.202215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427862295, states[0] = -95.208284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440345386, states[0] = -95.201154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449978912, states[0] = -95.235763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456788125, states[0] = -95.166018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469250294, states[0] = -95.128712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480403256, states[0] = -95.221423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492889139, states[0] = -95.217436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505368127, states[0] = -95.428654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517820553, states[0] = -55.434303, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1530697942, states[0] = -30.167725, states[40]= 0.000471
Saving checkpoint... 
Iteration: 1543147978, states[0] = -95.444926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555559193, states[0] = 3.786301, states[40]= 0.005219
Saving checkpoint... 
Iteration: 1567999164, states[0] = -95.388842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580370932, states[0] = -95.478454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592837797, states[0] = -87.809724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605324584, states[0] = 19.829848, states[40]= 0.008286
Saving checkpoint... 
Iteration: 1617783528, states[0] = -95.365499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630261739, states[0] = 1.976704, states[40]= 0.005040
Saving checkpoint... 
Iteration: 1642728380, states[0] = -95.440357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1654492067, states[0] = -95.498401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669508756, states[0] = 24.711772, states[40]= 0.069374
Saving checkpoint... 
Iteration: 1682084501, states[0] = -95.493713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694570900, states[0] = -95.338640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706233950, states[0] = -80.868088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719068814, states[0] = -2.880036, states[40]= 0.004267
Saving checkpoint... 
Iteration: 1731584060, states[0] = -95.493532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743266387, states[0] = -95.480191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755705241, states[0] = -39.714786, states[40]= 0.000145
Saving checkpoint... 
Iteration: 1768026909, states[0] = -68.099226, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1780743447, states[0] = -95.458524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793298103, states[0] = -95.395213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807925484, states[0] = -95.276735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820758903, states[0] = -95.174363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833409102, states[0] = -95.248014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846513242, states[0] = 22.726518, states[40]= 0.025509
Saving checkpoint... 
Iteration: 1859243613, states[0] = -95.132228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871916640, states[0] = -95.232596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884750161, states[0] = -95.133919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897244274, states[0] = -95.124936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910142720, states[0] = -58.159386, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1920275645, states[0] = -95.156929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932369645, states[0] = -95.212052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944838717, states[0] = -95.198600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957063019, states[0] = 7.849584, states[40]= 0.004805
Saving checkpoint... 
Iteration: 1967964100, states[0] = -95.233797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979531077, states[0] = 19.291559, states[40]= 0.005848
Saving checkpoint... 
Iteration: 1990292249, states[0] = -95.169136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002690436, states[0] = -95.032187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014627645, states[0] = -40.977049, states[40]= 0.000120
Saving checkpoint... 
Iteration: 2026993269, states[0] = -95.237176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038975935, states[0] = -95.234999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051361218, states[0] = -95.207452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054644455, states[0] = -60.049665, states[40]= 0.000006
Saving checkpoint... 
Iteration: 2067398966, states[0] = -95.219864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080057223, states[0] = 10.194635, states[40]= 0.004869
Saving checkpoint... 
Iteration: 2092457927, states[0] = -95.232286, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.113670
 - CaMKt in component CaMK (millimolar): 0.007097
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.557286
 - nass in component intracellular_ions (millimolar): 6.557348
 - ki in component intracellular_ions (millimolar): 145.419545
 - kss in component intracellular_ions (millimolar): 145.419523
 - cansr in component intracellular_ions (millimolar): 1.315254
 - cajsr in component intracellular_ions (millimolar): 1.276598
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003542
 - hf in component INa (dimensionless): 0.883628
 - hs in component INa (dimensionless): 0.883624
 - j in component INa (dimensionless): 0.883598
 - hsp in component INa (dimensionless): 0.732704
 - jp in component INa (dimensionless): 0.883581
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.714655
 - hLp in component INaL (dimensionless): 0.455892
 - a in component Ito (dimensionless): 0.000615
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.617911
 - ap in component Ito (dimensionless): 0.000313
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.692281
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930262
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999868
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001620
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335270
 - xs1 in component IKs (dimensionless): 0.251988
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997281
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:50:31 (8312): called boinc_finish(0)

</stderr_txt>
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