𝕏

Task 54929820

Name HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_423_1
Workunit 26083110
Created 27 Jun 2024, 4:20:43 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 30 Jun 2024, 14:04:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 39 sec
CPU time 1 hours 27 min 18 sec
Validate state Valid
Credit 58.93
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_423.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_423_1_r1864192537_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627062041487766_ORdGradInc_k_24-Pueyo_APDR-conf_423_1_r1864192537_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 124.006139
     * GNaL_b in INaL: 0.005987
     * Gto_b in Ito: 0.069158
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033449
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.149661
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 66.906857
     * GKb_b in IKb: 0.003849
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033600
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11940160, states[0] = -95.210948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23921296, states[0] = -95.175544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35500061, states[0] = -87.648074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47583425, states[0] = -10.093149, states[40]= 0.002430
Saving checkpoint... 
Iteration: 59220819, states[0] = -94.988896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71249879, states[0] = -95.025161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83334502, states[0] = -95.092625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95328448, states[0] = -95.086170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106875833, states[0] = -95.106063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118505157, states[0] = 31.972011, states[40]= 0.125297
Saving checkpoint... 
Iteration: 130442021, states[0] = -95.121640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142400647, states[0] = -95.110774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154188032, states[0] = -94.904645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165822725, states[0] = -95.076222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177847873, states[0] = -95.089550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189455018, states[0] = -95.121794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201460008, states[0] = -95.122499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213088692, states[0] = -13.714647, states[40]= 0.001722
Saving checkpoint... 
Iteration: 224729821, states[0] = -94.981942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236367382, states[0] = -95.097466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248293255, states[0] = -95.054385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260310243, states[0] = -95.067105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272368393, states[0] = -95.097759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284454198, states[0] = -95.121106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296483839, states[0] = -95.125712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308514935, states[0] = 23.670986, states[40]= 0.021530
Saving checkpoint... 
Iteration: 320525197, states[0] = 20.551002, states[40]= 0.008323
Saving checkpoint... 
Iteration: 332487622, states[0] = -95.126181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344478856, states[0] = -95.124980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356021515, states[0] = 21.717676, states[40]= 0.010259
Saving checkpoint... 
Iteration: 367582850, states[0] = -8.220438, states[40]= 0.002821
Saving checkpoint... 
Iteration: 379184404, states[0] = -94.894782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390830153, states[0] = -95.079451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402495253, states[0] = -95.127101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414249101, states[0] = -95.008815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426253766, states[0] = -95.014623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438274401, states[0] = -95.037259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450307219, states[0] = -95.064825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462371930, states[0] = -95.098992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473994126, states[0] = -95.126929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486028194, states[0] = 19.534532, states[40]= 0.007425
Saving checkpoint... 
Iteration: 498118746, states[0] = -44.954737, states[40]= 0.000058
Saving checkpoint... 
Iteration: 510152307, states[0] = -89.614508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522268447, states[0] = -95.031166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534230953, states[0] = -94.983336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546270311, states[0] = -95.033089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558278190, states[0] = -95.040868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569870282, states[0] = -95.098306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581836217, states[0] = -95.082706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593338959, states[0] = -95.084151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605373546, states[0] = -95.099537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617315706, states[0] = -95.070532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629317836, states[0] = -95.071904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641355346, states[0] = -95.092049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653382195, states[0] = -95.102643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664964985, states[0] = -95.122722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677050231, states[0] = 10.656485, states[40]= 0.005350
Saving checkpoint... 
Iteration: 688667142, states[0] = -94.768500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700659674, states[0] = -94.071432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712624772, states[0] = -51.839997, states[40]= 0.000019
Saving checkpoint... 
Iteration: 724359396, states[0] = -95.093785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736417559, states[0] = -95.113074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748497792, states[0] = -95.127242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 760132294, states[0] = -60.741807, states[40]= 0.000004
Saving checkpoint... 
Iteration: 772158310, states[0] = -93.708970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783687829, states[0] = -94.902427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795304246, states[0] = -95.062519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807268563, states[0] = -95.031154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818915605, states[0] = -95.112542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830549578, states[0] = 10.943261, states[40]= 0.005372
Saving checkpoint... 
Iteration: 842608906, states[0] = -34.378569, states[40]= 0.000263
Saving checkpoint... 
Iteration: 854296961, states[0] = -95.056965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866228898, states[0] = -94.979999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878115738, states[0] = -41.633357, states[40]= 0.000095
Saving checkpoint... 
Iteration: 890130360, states[0] = -58.412310, states[40]= 0.000006
Saving checkpoint... 
Iteration: 902142305, states[0] = -74.151857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913806157, states[0] = -95.063849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925889105, states[0] = -95.104839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 937939038, states[0] = -95.117858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949925552, states[0] = -95.114903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961528067, states[0] = 19.578910, states[40]= 0.007456
Saving checkpoint... 
Iteration: 973514909, states[0] = 23.679236, states[40]= 0.021620
Saving checkpoint... 
Iteration: 985511728, states[0] = 24.789140, states[40]= 0.038585
Saving checkpoint... 
Iteration: 997103572, states[0] = -28.863328, states[40]= 0.000491
Saving checkpoint... 
Iteration: 1009068432, states[0] = 1.829704, states[40]= 0.004673
Saving checkpoint... 
Iteration: 1020674247, states[0] = -94.861471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032295051, states[0] = -95.055365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044334034, states[0] = -95.081306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056351205, states[0] = -95.089968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068309912, states[0] = -95.066423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079523812, states[0] = 21.000461, states[40]= 0.008904
Saving checkpoint... 
Iteration: 1091575383, states[0] = -2.434571, states[40]= 0.004043
Saving checkpoint... 
Iteration: 1103626300, states[0] = -53.620183, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1115235477, states[0] = -94.989841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127219010, states[0] = -94.963647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139217508, states[0] = -94.961040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150806329, states[0] = -95.063861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162769828, states[0] = -95.032302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174783314, states[0] = -95.045318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186439789, states[0] = -95.117895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198100878, states[0] = -26.096323, states[40]= 0.000623
Saving checkpoint... 
Iteration: 1210124326, states[0] = -51.322123, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1222038089, states[0] = 15.791081, states[40]= 0.005989
Saving checkpoint... 
Iteration: 1233970616, states[0] = -95.123341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245590838, states[0] = -15.843844, states[40]= 0.001403
Saving checkpoint... 
Iteration: 1257181144, states[0] = -94.886268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269110242, states[0] = -35.773484, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1281062424, states[0] = 4.989165, states[40]= 0.004971
Saving checkpoint... 
Iteration: 1292768646, states[0] = -95.031012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304344489, states[0] = -95.086630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316395941, states[0] = -95.106813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328436009, states[0] = -95.117044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340456124, states[0] = -95.120915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352108344, states[0] = -33.793647, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1363755311, states[0] = -95.016046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375812437, states[0] = -95.068004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387388663, states[0] = -95.104479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399398740, states[0] = -95.107619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411418182, states[0] = -95.112914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423414196, states[0] = -95.111897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435416586, states[0] = -95.112502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447465851, states[0] = -95.122495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459374650, states[0] = -95.099551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470593137, states[0] = -18.176001, states[40]= 0.001134
Saving checkpoint... 
Iteration: 1482546291, states[0] = 12.368374, states[40]= 0.005494
Saving checkpoint... 
Iteration: 1494581366, states[0] = -6.951675, states[40]= 0.003105
Saving checkpoint... 
Iteration: 1506228513, states[0] = -95.307288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517803630, states[0] = -45.630251, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1529800702, states[0] = -42.905295, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1541711575, states[0] = 25.518773, states[40]= 0.040662
Saving checkpoint... 
Iteration: 1553553283, states[0] = -95.185180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565094330, states[0] = -95.421126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576654573, states[0] = -95.202223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588637091, states[0] = -93.858686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600654993, states[0] = -95.208921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612729345, states[0] = -95.367474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624516962, states[0] = 22.919193, states[40]= 0.017638
Saving checkpoint... 
Iteration: 1636229970, states[0] = 17.235827, states[40]= 0.008013
Saving checkpoint... 
Iteration: 1648225424, states[0] = 19.331875, states[40]= 0.009359
Saving checkpoint... 
Iteration: 1660273414, states[0] = -12.726966, states[40]= 0.002120
Saving checkpoint... 
Iteration: 1672241193, states[0] = 11.472638, states[40]= 0.006462
Saving checkpoint... 
Iteration: 1684277534, states[0] = -17.473643, states[40]= 0.001339
Saving checkpoint... 
Iteration: 1696260152, states[0] = -0.294245, states[40]= 0.004909
Saving checkpoint... 
Iteration: 1707863452, states[0] = -95.407999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1719788121, states[0] = -95.300231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731826571, states[0] = -95.366186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743884919, states[0] = -95.425826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755884103, states[0] = -95.425227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767799598, states[0] = -95.322919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779804940, states[0] = -95.332539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791422770, states[0] = -75.458049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803372170, states[0] = -95.166561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815315053, states[0] = -95.120175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826774852, states[0] = -95.074649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838854524, states[0] = -95.117839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850890566, states[0] = -95.123839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862849794, states[0] = -95.102444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874890652, states[0] = -95.114474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886918677, states[0] = -95.119618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898882946, states[0] = -95.107169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910469659, states[0] = -95.126364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922447396, states[0] = -95.121528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933624931, states[0] = -52.159524, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1945622833, states[0] = -49.691852, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1957217850, states[0] = -94.962186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1969189656, states[0] = -94.906556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980760806, states[0] = -95.022617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992746035, states[0] = -95.004418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004758446, states[0] = -95.019657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016773567, states[0] = -95.035834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028762125, states[0] = -95.023709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040721299, states[0] = -94.967167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052674897, states[0] = -94.864379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064662699, states[0] = -94.523925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076639340, states[0] = -69.829853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 2088242414, states[0] = -94.999184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099845239, states[0] = -95.086607, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.002724
 - CaMKt in component CaMK (millimolar): 0.006412
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.582503
 - nass in component intracellular_ions (millimolar): 6.582563
 - ki in component intracellular_ions (millimolar): 145.402035
 - kss in component intracellular_ions (millimolar): 145.402015
 - cansr in component intracellular_ions (millimolar): 1.287647
 - cajsr in component intracellular_ions (millimolar): 1.251081
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003582
 - hf in component INa (dimensionless): 0.881740
 - hs in component INa (dimensionless): 0.881735
 - j in component INa (dimensionless): 0.881707
 - hsp in component INa (dimensionless): 0.729116
 - jp in component INa (dimensionless): 0.881688
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.714360
 - hLp in component INaL (dimensionless): 0.460479
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.629971
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.706014
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937618
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999896
 - jca in component ICaL (dimensionless): 0.999981
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001530
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339866
 - xs1 in component IKs (dimensionless): 0.231204
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997310
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:04:20 (237436): called boinc_finish(0)

</stderr_txt>
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