Task 54929584

Name	HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_853_1
Workunit	26082998
Created	27 Jun 2024, 4:05:49 UTC
Sent	27 Jun 2024, 5:23:34 UTC
Report deadline	30 Jun 2024, 14:59:34 UTC
Received	30 Jun 2024, 14:05:03 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	237767
Run time	1 hours 28 min 55 sec
CPU time	1 hours 27 min 29 sec
Validate state	Valid
Credit	60.76
Device peak FLOPS	4.40 GFLOPS
Application version	Human ventricular cell models optimization v0.02 x86_64-pc-linux-gnu
Peak working set size	2.50 MB
Peak swap size	3.82 MB
Peak disk usage	0.24 MB
Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_853.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_853_1_r872387567_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_853_1_r872387567_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 109.642787
     * GNaL_b in INaL: 0.005502
     * Gto_b in Ito: 0.066779
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.034048
     * GKs_b in IKs: 0.001822
     * GK1_b in IK1: 0.162950
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 69.454078
     * GKb_b in IKb: 0.003767
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052246
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11960467, states[0] = -95.310182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23608980, states[0] = -41.239422, states[40]= 0.000094
Saving checkpoint... 
Iteration: 35274204, states[0] = -95.186187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46834024, states[0] = -95.209096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58406073, states[0] = -95.223331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70373190, states[0] = -95.207557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82405995, states[0] = -95.211631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94085971, states[0] = -12.715407, states[40]= 0.001888
Saving checkpoint... 
Iteration: 106140757, states[0] = -78.086553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118106310, states[0] = -33.925115, states[40]= 0.000263
Saving checkpoint... 
Iteration: 130113549, states[0] = -41.786621, states[40]= 0.000088
Saving checkpoint... 
Iteration: 142122333, states[0] = -51.990664, states[40]= 0.000018
Saving checkpoint... 
Iteration: 153743117, states[0] = -95.110044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165783155, states[0] = -95.147020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177780249, states[0] = -95.144467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189780923, states[0] = -95.144760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201784575, states[0] = -95.147370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213495750, states[0] = -95.214415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225519498, states[0] = 22.314223, states[40]= 0.012068
Saving checkpoint... 
Iteration: 237400269, states[0] = -95.198732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248974977, states[0] = -95.211906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260981446, states[0] = -95.212640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273049463, states[0] = 10.717535, states[40]= 0.005328
Saving checkpoint... 
Iteration: 284663448, states[0] = -94.927432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296604469, states[0] = -31.651878, states[40]= 0.000346
Saving checkpoint... 
Iteration: 308254198, states[0] = -95.120384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320228364, states[0] = -95.090256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332242137, states[0] = -95.107293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343865933, states[0] = -95.188633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355365684, states[0] = -95.188542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367398208, states[0] = -95.198025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379413753, states[0] = -95.201634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391391178, states[0] = -95.196198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403353727, states[0] = -95.184232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414965370, states[0] = -95.210497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426960059, states[0] = -95.209761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438940631, states[0] = -95.206755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450878918, states[0] = -95.192707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462905858, states[0] = -95.199824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474495849, states[0] = -95.214028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486479904, states[0] = -95.212289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497622224, states[0] = -51.676448, states[40]= 0.000019
Saving checkpoint... 
Iteration: 509645595, states[0] = -85.955337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521709548, states[0] = -95.062728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533689201, states[0] = -95.027355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545564853, states[0] = 3.315478, states[40]= 0.004790
Saving checkpoint... 
Iteration: 557062636, states[0] = 4.474612, states[40]= 0.004892
Saving checkpoint... 
Iteration: 569115778, states[0] = -44.087365, states[40]= 0.000062
Saving checkpoint... 
Iteration: 580759612, states[0] = -95.125604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592413536, states[0] = -95.201492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604451673, states[0] = -95.208454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616446780, states[0] = -95.207686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628468566, states[0] = -95.210826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640416162, states[0] = -95.202034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651941849, states[0] = -95.206866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663427218, states[0] = -95.204247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675521171, states[0] = 21.803611, states[40]= 0.010505
Saving checkpoint... 
Iteration: 687458269, states[0] = -95.209393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699431749, states[0] = -95.205079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711328983, states[0] = -95.173515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722909121, states[0] = -95.200459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734445697, states[0] = -95.207461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746456098, states[0] = -95.209053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758424486, states[0] = -95.203677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769935705, states[0] = -95.205760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781925990, states[0] = -95.203959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793522007, states[0] = 21.541548, states[40]= 0.009906
Saving checkpoint... 
Iteration: 805511177, states[0] = 25.036613, states[40]= 0.041829
Saving checkpoint... 
Iteration: 817427693, states[0] = -95.204270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829397198, states[0] = -95.197566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841327226, states[0] = -95.172606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853371496, states[0] = -95.190234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864977482, states[0] = -95.211837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876599832, states[0] = -26.708311, states[40]= 0.000566
Saving checkpoint... 
Iteration: 888445856, states[0] = -95.207420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900156959, states[0] = -94.568296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912213322, states[0] = -95.068464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923915649, states[0] = -95.201801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935899685, states[0] = -95.198140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947846842, states[0] = -95.181297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959470883, states[0] = -95.210980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970700821, states[0] = -95.048076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982348472, states[0] = -95.181936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994283161, states[0] = -95.145564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006295531, states[0] = -95.154359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018263838, states[0] = -95.129394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030217496, states[0] = -95.074704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042195913, states[0] = -95.039435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053815302, states[0] = -95.166332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065794776, states[0] = -95.153827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077442599, states[0] = -95.206806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089310099, states[0] = -95.163384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101214107, states[0] = -95.069584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112315400, states[0] = -95.166360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124342779, states[0] = -95.179543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136325495, states[0] = -95.171624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147970190, states[0] = -95.210810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159966998, states[0] = -95.210389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171584148, states[0] = -10.441047, states[40]= 0.002325
Saving checkpoint... 
Iteration: 1183210157, states[0] = -95.063405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194771798, states[0] = -95.136361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206733557, states[0] = -95.096564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218633273, states[0] = -65.654002, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1230242462, states[0] = -95.107264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241799108, states[0] = -95.156604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253778836, states[0] = -95.142105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265720915, states[0] = -95.079569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277203926, states[0] = -95.053211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289405908, states[0] = -95.199476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300971316, states[0] = -95.210887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312482688, states[0] = -95.212252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324440205, states[0] = -95.206297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336403565, states[0] = -95.198905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347997001, states[0] = -95.213764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359982217, states[0] = -95.212177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371949990, states[0] = -95.207862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383945266, states[0] = -95.207109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395472438, states[0] = -95.210988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407470422, states[0] = -95.210727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419129014, states[0] = -60.040175, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1431144600, states[0] = -84.226291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443095461, states[0] = -22.075882, states[40]= 0.000811
Saving checkpoint... 
Iteration: 1455034855, states[0] = 16.931070, states[40]= 0.006285
Saving checkpoint... 
Iteration: 1466720229, states[0] = -95.078498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478755525, states[0] = -95.121194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490371221, states[0] = -95.189869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501966805, states[0] = -95.279533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513956376, states[0] = -95.267120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525900005, states[0] = -43.866335, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1537858777, states[0] = 0.917864, states[40]= 0.005036
Saving checkpoint... 
Iteration: 1549789873, states[0] = -95.472940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561746612, states[0] = -95.445161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573574569, states[0] = -14.700541, states[40]= 0.001739
Saving checkpoint... 
Iteration: 1585530740, states[0] = 16.818313, states[40]= 0.007792
Saving checkpoint... 
Iteration: 1597505848, states[0] = 31.115479, states[40]= 0.098169
Saving checkpoint... 
Iteration: 1609489484, states[0] = -95.485910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621245465, states[0] = 8.884428, states[40]= 0.006048
Saving checkpoint... 
Iteration: 1632823141, states[0] = -95.429636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644694892, states[0] = -39.600886, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1656291655, states[0] = -95.489019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668242395, states[0] = -95.451516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680248779, states[0] = -95.457701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691808109, states[0] = -56.947898, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1703334003, states[0] = -95.443092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714850862, states[0] = 5.612676, states[40]= 0.005664
Saving checkpoint... 
Iteration: 1726864774, states[0] = -4.634399, states[40]= 0.003991
Saving checkpoint... 
Iteration: 1738501195, states[0] = 50.640988, states[40]= 0.023891
Saving checkpoint... 
Iteration: 1750508337, states[0] = 27.563634, states[40]= 0.070545
Saving checkpoint... 
Iteration: 1762474016, states[0] = -95.478196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774472795, states[0] = -95.477334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786084578, states[0] = -95.372119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798093204, states[0] = -95.387459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810095033, states[0] = -25.161389, states[40]= 0.000654
Saving checkpoint... 
Iteration: 1822081121, states[0] = -9.630501, states[40]= 0.002528
Saving checkpoint... 
Iteration: 1834222548, states[0] = -95.107818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846278720, states[0] = -95.160181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857816632, states[0] = -95.179880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869353698, states[0] = -95.193015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880901302, states[0] = -95.204888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892870059, states[0] = -95.194126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904845468, states[0] = -95.183737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916768371, states[0] = -95.135537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928668264, states[0] = -94.977418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940580280, states[0] = -7.001376, states[40]= 0.003073
Saving checkpoint... 
Iteration: 1952087322, states[0] = -13.628487, states[40]= 0.001725
Saving checkpoint... 
Iteration: 1963695104, states[0] = -95.038214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975616256, states[0] = -44.673539, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1987147573, states[0] = -89.035535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998686466, states[0] = -95.021743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010580556, states[0] = -7.184005, states[40]= 0.003032
Saving checkpoint... 
Iteration: 2022537143, states[0] = 16.006481, states[40]= 0.006043
Saving checkpoint... 
Iteration: 2034507560, states[0] = 27.530747, states[40]= 0.085948
Saving checkpoint... 
Iteration: 2046437346, states[0] = -95.205519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058387176, states[0] = -95.194392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069938573, states[0] = -95.205691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081975971, states[0] = -95.211113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093965674, states[0] = -95.209787, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.089585
 - CaMKt in component CaMK (millimolar): 0.006151
 - cass in component intracellular_ions (millimolar): 0.000072
 - nai in component intracellular_ions (millimolar): 6.484242
 - nass in component intracellular_ions (millimolar): 6.484300
 - ki in component intracellular_ions (millimolar): 145.504749
 - kss in component intracellular_ions (millimolar): 145.504729
 - cansr in component intracellular_ions (millimolar): 1.268209
 - cajsr in component intracellular_ions (millimolar): 1.232112
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003551
 - hf in component INa (dimensionless): 0.883220
 - hs in component INa (dimensionless): 0.883216
 - j in component INa (dimensionless): 0.883193
 - hsp in component INa (dimensionless): 0.731930
 - jp in component INa (dimensionless): 0.883177
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.717511
 - hLp in component INaL (dimensionless): 0.465905
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.633451
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.710303
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938702
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999900
 - jca in component ICaL (dimensionless): 0.999982
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001452
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331598
 - xs1 in component IKs (dimensionless): 0.228386
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997287
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:04:53 (237434): called boinc_finish(0)

</stderr_txt>
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