𝕏

Task 54929575

Name HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_933_0
Workunit 26082994
Created 27 Jun 2024, 4:05:49 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 10:27:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 11 sec
CPU time 1 hours 27 min 1 sec
Validate state Valid
Credit 57.27
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_933.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_933_0_r1677679791_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060544394880_ORdGradInc_k_24-Pueyo_APDR-conf_933_0_r1677679791_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.626630
     * GNaL_b in INaL: 0.006067
     * Gto_b in Ito: 0.066569
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032726
     * GKs_b in IKs: 0.001873
     * GK1_b in IK1: 0.157301
     * Gncx_b in INaCa_i: 0.000959
     * Pnak_b in INaK: 69.008881
     * GKb_b in IKb: 0.003784
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044231
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12472816, states[0] = -95.132247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24564552, states[0] = 3.394515, states[40]= 0.004845
Saving checkpoint... 
Iteration: 36767863, states[0] = -94.995130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48415324, states[0] = -95.059704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60402368, states[0] = -95.048025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72484144, states[0] = -95.057496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84519470, states[0] = 22.708346, states[40]= 0.011715
Saving checkpoint... 
Iteration: 96601375, states[0] = -24.781492, states[40]= 0.000699
Saving checkpoint... 
Iteration: 108339983, states[0] = -95.010465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120420550, states[0] = -95.036338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132447490, states[0] = -95.040721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144388920, states[0] = -95.026283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156382039, states[0] = -95.023609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167918429, states[0] = -95.033278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179825566, states[0] = -94.998666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191726952, states[0] = -94.904144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203330912, states[0] = -95.001260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215454885, states[0] = -95.039735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227585819, states[0] = -9.209768, states[40]= 0.002582
Saving checkpoint... 
Iteration: 239751389, states[0] = -94.936565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251345855, states[0] = -95.008380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262900143, states[0] = -95.027804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274873931, states[0] = -95.019631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286374573, states[0] = -95.019838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297999172, states[0] = -95.045421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310020644, states[0] = 22.455739, states[40]= 0.010629
Saving checkpoint... 
Iteration: 322030830, states[0] = 19.108426, states[40]= 0.006768
Saving checkpoint... 
Iteration: 334061097, states[0] = 6.398951, states[40]= 0.005036
Saving checkpoint... 
Iteration: 346033411, states[0] = 18.154828, states[40]= 0.006395
Saving checkpoint... 
Iteration: 358085589, states[0] = -8.998858, states[40]= 0.002627
Saving checkpoint... 
Iteration: 370085187, states[0] = -8.646444, states[40]= 0.002705
Saving checkpoint... 
Iteration: 382150372, states[0] = -82.950706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394203191, states[0] = -94.863538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406216519, states[0] = -94.887021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418251718, states[0] = -94.936752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430322184, states[0] = -94.995994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442333159, states[0] = -95.002004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454398440, states[0] = -95.027182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466482715, states[0] = -95.043401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478457295, states[0] = -95.039773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490442831, states[0] = -95.037282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502559196, states[0] = 7.290551, states[40]= 0.005092
Saving checkpoint... 
Iteration: 514634539, states[0] = -60.002886, states[40]= 0.000005
Saving checkpoint... 
Iteration: 526751998, states[0] = -94.937027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538777950, states[0] = -94.963799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550384130, states[0] = -95.022867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562102858, states[0] = -25.856795, states[40]= 0.000647
Saving checkpoint... 
Iteration: 574128472, states[0] = -52.908175, states[40]= 0.000017
Saving checkpoint... 
Iteration: 586191266, states[0] = -94.840374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598283768, states[0] = -94.968858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610401316, states[0] = -95.027896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622435037, states[0] = -95.035731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634478749, states[0] = -95.042810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646133074, states[0] = -58.258675, states[40]= 0.000007
Saving checkpoint... 
Iteration: 658247917, states[0] = -94.932065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670268128, states[0] = -94.954427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682445343, states[0] = -95.037644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694476678, states[0] = -95.042507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706575124, states[0] = -1.137260, states[40]= 0.004237
Saving checkpoint... 
Iteration: 717384486, states[0] = -95.022899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729453834, states[0] = -95.039085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741034599, states[0] = 17.704026, states[40]= 0.006254
Saving checkpoint... 
Iteration: 752585113, states[0] = -8.581713, states[40]= 0.002719
Saving checkpoint... 
Iteration: 764554341, states[0] = 9.490967, states[40]= 0.005219
Saving checkpoint... 
Iteration: 776500746, states[0] = 44.947737, states[40]= 0.008501
Saving checkpoint... 
Iteration: 788170891, states[0] = -94.749459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799816160, states[0] = -94.992223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811723644, states[0] = -94.898307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823756515, states[0] = -94.942068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835828848, states[0] = -94.999524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847867846, states[0] = -95.017109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859725529, states[0] = -94.901197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871893771, states[0] = -95.025648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883540920, states[0] = 15.200691, states[40]= 0.005724
Saving checkpoint... 
Iteration: 895541567, states[0] = 14.936152, states[40]= 0.005685
Saving checkpoint... 
Iteration: 907624801, states[0] = -48.738148, states[40]= 0.000033
Saving checkpoint... 
Iteration: 919674432, states[0] = -94.789435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931598310, states[0] = -21.306946, states[40]= 0.000887
Saving checkpoint... 
Iteration: 943634546, states[0] = -60.010923, states[40]= 0.000005
Saving checkpoint... 
Iteration: 955672565, states[0] = -94.772671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967286129, states[0] = -94.970657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978987474, states[0] = -95.043736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991105425, states[0] = -28.429705, states[40]= 0.000523
Saving checkpoint... 
Iteration: 1003120304, states[0] = -43.768972, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1014679393, states[0] = -94.812607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026326802, states[0] = -94.998311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037868248, states[0] = -95.017165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049853423, states[0] = -95.011259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061858932, states[0] = -95.013544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073825408, states[0] = -94.997512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085907735, states[0] = -95.029352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097895063, states[0] = -95.025910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109978559, states[0] = -95.042552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121904495, states[0] = -95.028495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133496639, states[0] = -95.044715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145522826, states[0] = 21.798031, states[40]= 0.009163
Saving checkpoint... 
Iteration: 1157544901, states[0] = 13.553872, states[40]= 0.005518
Saving checkpoint... 
Iteration: 1169667064, states[0] = -94.631448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181830796, states[0] = -95.000399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193917376, states[0] = -95.031653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205982896, states[0] = -95.043062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218012708, states[0] = 24.793284, states[40]= 0.030636
Saving checkpoint... 
Iteration: 1229703473, states[0] = -94.863647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241386684, states[0] = -95.023333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253297092, states[0] = -94.979118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264953714, states[0] = -95.038803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276566653, states[0] = 3.659219, states[40]= 0.004827
Saving checkpoint... 
Iteration: 1288752080, states[0] = -94.936748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300808540, states[0] = -94.987120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312462266, states[0] = -95.040143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324205302, states[0] = -94.866966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336240412, states[0] = -94.922175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348326633, states[0] = -94.998059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360353065, states[0] = -95.010953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372449820, states[0] = -95.038092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384410228, states[0] = -95.029835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396539331, states[0] = 15.844582, states[40]= 0.005829
Saving checkpoint... 
Iteration: 1408575294, states[0] = -1.244557, states[40]= 0.004219
Saving checkpoint... 
Iteration: 1420238447, states[0] = -94.919509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431963296, states[0] = -95.040241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443989780, states[0] = -95.043782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456064428, states[0] = 4.784328, states[40]= 0.004922
Saving checkpoint... 
Iteration: 1468114123, states[0] = -37.244944, states[40]= 0.000184
Saving checkpoint... 
Iteration: 1480212922, states[0] = -94.880404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492282487, states[0] = -94.967324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504430425, states[0] = -95.219587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516053153, states[0] = -95.049660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528110536, states[0] = -95.216505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539715151, states[0] = -58.753515, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1551381960, states[0] = -19.693732, states[40]= 0.001088
Saving checkpoint... 
Iteration: 1563448930, states[0] = -95.035884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575325731, states[0] = 19.765461, states[40]= 0.009055
Saving checkpoint... 
Iteration: 1587269192, states[0] = -95.310550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599258709, states[0] = -95.302936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610856196, states[0] = -95.125470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622570229, states[0] = -95.167094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634213769, states[0] = -58.430683, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1646200092, states[0] = -41.282230, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1658278455, states[0] = -95.187012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670338533, states[0] = -95.285050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682343188, states[0] = -95.290379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693899941, states[0] = -41.137065, states[40]= 0.000109
Saving checkpoint... 
Iteration: 1705870449, states[0] = -7.813325, states[40]= 0.003234
Saving checkpoint... 
Iteration: 1717933831, states[0] = -89.934590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729933139, states[0] = -89.033934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741961687, states[0] = -95.146712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753857296, states[0] = 2.708560, states[40]= 0.005327
Saving checkpoint... 
Iteration: 1765477294, states[0] = -95.321721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776600559, states[0] = 15.096177, states[40]= 0.000445
Saving checkpoint... 
Iteration: 1788603456, states[0] = 39.101794, states[40]= 0.097787
Saving checkpoint... 
Iteration: 1800511509, states[0] = 24.756781, states[40]= 0.038138
Saving checkpoint... 
Iteration: 1812476501, states[0] = -95.090131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824061827, states[0] = 5.256839, states[40]= 0.005006
Saving checkpoint... 
Iteration: 1836009752, states[0] = 25.897890, states[40]= 0.056055
Saving checkpoint... 
Iteration: 1847940099, states[0] = -95.054010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859529569, states[0] = 19.409115, states[40]= 0.006984
Saving checkpoint... 
Iteration: 1871507917, states[0] = 27.358717, states[40]= 0.082203
Saving checkpoint... 
Iteration: 1883477855, states[0] = -95.048455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895078160, states[0] = -3.312786, states[40]= 0.003856
Saving checkpoint... 
Iteration: 1906564312, states[0] = 4.765384, states[40]= 0.004924
Saving checkpoint... 
Iteration: 1918178170, states[0] = -94.810585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930194609, states[0] = -94.848027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942247139, states[0] = -94.931640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954286133, states[0] = -94.970981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966209893, states[0] = -94.875461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978314545, states[0] = -94.991029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989965183, states[0] = -95.040513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001566641, states[0] = 3.660245, states[40]= 0.004828
Saving checkpoint... 
Iteration: 2013536409, states[0] = 17.002092, states[40]= 0.006069
Saving checkpoint... 
Iteration: 2025517168, states[0] = 23.453888, states[40]= 0.015070
Saving checkpoint... 
Iteration: 2037522727, states[0] = 21.827910, states[40]= 0.009217
Saving checkpoint... 
Iteration: 2049731686, states[0] = -94.909780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062082637, states[0] = -6.504972, states[40]= 0.003181
Saving checkpoint... 
Iteration: 2074370088, states[0] = -95.017319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086379008, states[0] = -95.020420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098338452, states[0] = -95.003843, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.920454
 - CaMKt in component CaMK (millimolar): 0.006506
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.570953
 - nass in component intracellular_ions (millimolar): 6.571011
 - ki in component intracellular_ions (millimolar): 145.412874
 - kss in component intracellular_ions (millimolar): 145.412855
 - cansr in component intracellular_ions (millimolar): 1.290030
 - cajsr in component intracellular_ions (millimolar): 1.253101
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880323
 - hs in component INa (dimensionless): 0.880319
 - j in component INa (dimensionless): 0.880292
 - hsp in component INa (dimensionless): 0.726440
 - jp in component INa (dimensionless): 0.880275
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711730
 - hLp in component INaL (dimensionless): 0.456538
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.626739
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.702009
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935380
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001536
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341104
 - xs1 in component IKs (dimensionless): 0.235919
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:27:22 (233277): called boinc_finish(0)

</stderr_txt>
]]>