𝕏

Task 54929519

Name HuVeMOp_20240627060541680039_ORdGradInc_k_24-Pueyo_APDR-conf_960_0
Workunit 26082966
Created 27 Jun 2024, 4:05:44 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 7:31:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 39 sec
CPU time 1 hours 27 min 22 sec
Validate state Valid
Credit 61.14
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060541680039_ORdGradInc_k_24-Pueyo_APDR-conf_960.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060541680039_ORdGradInc_k_24-Pueyo_APDR-conf_960_0_r42217777_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060541680039_ORdGradInc_k_24-Pueyo_APDR-conf_960_0_r42217777_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.516582
     * GNaL_b in INaL: 0.008473
     * Gto_b in Ito: 0.090188
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032293
     * GKs_b in IKs: 0.001818
     * GK1_b in IK1: 0.162473
     * Gncx_b in INaCa_i: 0.000951
     * Pnak_b in INaK: 62.273529
     * GKb_b in IKb: 0.003898
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046952
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11982302, states[0] = -95.180505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24036290, states[0] = 17.912768, states[40]= 0.005097
Saving checkpoint... 
Iteration: 35558305, states[0] = 10.356810, states[40]= 0.004781
Saving checkpoint... 
Iteration: 47538975, states[0] = 17.241541, states[40]= 0.004970
Saving checkpoint... 
Iteration: 59519435, states[0] = 22.019068, states[40]= 0.009202
Saving checkpoint... 
Iteration: 71495439, states[0] = -95.148734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83447655, states[0] = -95.139770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95431747, states[0] = -95.135354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107346415, states[0] = -95.105396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118916843, states[0] = -95.130436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130533777, states[0] = 18.952207, states[40]= 0.005236
Saving checkpoint... 
Iteration: 142506017, states[0] = 25.553685, states[40]= 0.133684
Saving checkpoint... 
Iteration: 154069040, states[0] = 6.306036, states[40]= 0.004687
Saving checkpoint... 
Iteration: 165639442, states[0] = -49.853090, states[40]= 0.000034
Saving checkpoint... 
Iteration: 177548825, states[0] = 14.100831, states[40]= 0.004798
Saving checkpoint... 
Iteration: 189485974, states[0] = -95.142168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200969889, states[0] = -95.139783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212942817, states[0] = -95.134937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224880495, states[0] = -95.117918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236880340, states[0] = -95.117832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248876052, states[0] = -95.116229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260877172, states[0] = -95.116628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272888676, states[0] = -95.120664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284825967, states[0] = -95.091972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296767322, states[0] = -95.043047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308740375, states[0] = -95.008592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320724622, states[0] = -94.983725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332677400, states[0] = -94.546996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344149417, states[0] = -61.388951, states[40]= 0.000005
Saving checkpoint... 
Iteration: 356114936, states[0] = -26.052317, states[40]= 0.000734
Saving checkpoint... 
Iteration: 367679342, states[0] = -94.708341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379706789, states[0] = -94.951046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391303197, states[0] = -95.076249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403204947, states[0] = -94.947390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415160727, states[0] = -77.628676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426690386, states[0] = -94.912178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438215576, states[0] = -94.967662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450098068, states[0] = -11.200804, states[40]= 0.002060
Saving checkpoint... 
Iteration: 461975430, states[0] = -95.140284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473877544, states[0] = -95.116578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485374651, states[0] = -95.115483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496919465, states[0] = -95.129385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508508613, states[0] = 23.473175, states[40]= 0.072803
Saving checkpoint... 
Iteration: 520478683, states[0] = -95.140712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532399054, states[0] = -95.123744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544385973, states[0] = -95.119526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555967149, states[0] = -95.138941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567450229, states[0] = -95.136004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579387846, states[0] = -95.120135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591265117, states[0] = -95.040339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602831663, states[0] = -95.095103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614435905, states[0] = -95.133099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626003818, states[0] = 31.438812, states[40]= 0.173422
Saving checkpoint... 
Iteration: 637980704, states[0] = -95.140910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649964631, states[0] = -95.138463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661996345, states[0] = -95.142933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673979711, states[0] = -95.140743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685960864, states[0] = -95.137808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697822822, states[0] = -95.089692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709732939, states[0] = -94.997011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721269014, states[0] = -95.044575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733204553, states[0] = -94.946353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744730782, states[0] = -94.993561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756684459, states[0] = -94.868368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768672614, states[0] = -93.385686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780663779, states[0] = -83.030559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792622402, states[0] = -32.773204, states[40]= 0.000395
Saving checkpoint... 
Iteration: 804562997, states[0] = 8.829292, states[40]= 0.004758
Saving checkpoint... 
Iteration: 816537525, states[0] = 17.852546, states[40]= 0.005028
Saving checkpoint... 
Iteration: 828480044, states[0] = -95.140673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840447213, states[0] = -95.135224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852392599, states[0] = -95.121490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864019198, states[0] = 22.123934, states[40]= 0.009462
Saving checkpoint... 
Iteration: 876038532, states[0] = 17.539817, states[40]= 0.004987
Saving checkpoint... 
Iteration: 888043168, states[0] = 16.040720, states[40]= 0.004859
Saving checkpoint... 
Iteration: 900067955, states[0] = 6.784785, states[40]= 0.004704
Saving checkpoint... 
Iteration: 912036533, states[0] = 18.155410, states[40]= 0.005074
Saving checkpoint... 
Iteration: 924058630, states[0] = 10.531331, states[40]= 0.004777
Saving checkpoint... 
Iteration: 935957397, states[0] = -95.137022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947550448, states[0] = 13.533031, states[40]= 0.004791
Saving checkpoint... 
Iteration: 959526041, states[0] = 20.927288, states[40]= 0.006193
Saving checkpoint... 
Iteration: 971492471, states[0] = -95.142221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982993181, states[0] = -95.142302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994932012, states[0] = -95.131962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006523753, states[0] = 21.392697, states[40]= 0.006801
Saving checkpoint... 
Iteration: 1018440985, states[0] = -95.133855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030408455, states[0] = -95.126086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042339043, states[0] = -95.098883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053896055, states[0] = -95.122429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065861003, states[0] = -95.109489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077458010, states[0] = -95.137022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089397712, states[0] = -95.122914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100939978, states[0] = -95.133586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112863513, states[0] = -95.110530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124837288, states[0] = -95.097869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136796145, states[0] = -95.070067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148817007, states[0] = -95.085574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160691036, states[0] = -94.914010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172325620, states[0] = -95.091073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183947688, states[0] = -95.135055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195954143, states[0] = -95.136247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207899510, states[0] = -95.123370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220218415, states[0] = -94.972208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232439384, states[0] = -95.133364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244407010, states[0] = -95.125522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256617821, states[0] = -28.628159, states[40]= 0.000606
Saving checkpoint... 
Iteration: 1268475599, states[0] = -95.139698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280529703, states[0] = 20.065530, states[40]= 0.005610
Saving checkpoint... 
Iteration: 1292170548, states[0] = -92.170549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304150724, states[0] = -63.011071, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1315873450, states[0] = -95.114393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327787606, states[0] = -95.062561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340003403, states[0] = 33.469547, states[40]= 0.168977
Saving checkpoint... 
Iteration: 1351585480, states[0] = -2.013177, states[40]= 0.003889
Saving checkpoint... 
Iteration: 1363225430, states[0] = -94.984291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374824720, states[0] = -95.090364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386809888, states[0] = -95.080461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398876726, states[0] = -95.115573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410855898, states[0] = -95.106955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422860009, states[0] = -95.108784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434791944, states[0] = -95.066299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446776229, states[0] = -95.051604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458735648, states[0] = -95.000640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470690388, states[0] = -94.911384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482708780, states[0] = -94.954075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494266163, states[0] = -95.040832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506246398, states[0] = -95.321711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517810485, states[0] = -39.943839, states[40]= 0.000151
Saving checkpoint... 
Iteration: 1529477060, states[0] = -6.936170, states[40]= 0.003341
Saving checkpoint... 
Iteration: 1541411035, states[0] = 23.535551, states[40]= 0.041181
Saving checkpoint... 
Iteration: 1553460528, states[0] = 4.052431, states[40]= 0.005234
Saving checkpoint... 
Iteration: 1565099746, states[0] = -95.412698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576689252, states[0] = -95.276628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588678230, states[0] = -95.253286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600582506, states[0] = -13.338818, states[40]= 0.001937
Saving checkpoint... 
Iteration: 1612165965, states[0] = -95.394650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624136378, states[0] = -95.362885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636128587, states[0] = -95.352873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648057689, states[0] = -95.149671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659733466, states[0] = -73.376586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1671629578, states[0] = 18.337464, states[40]= 0.006652
Saving checkpoint... 
Iteration: 1683429418, states[0] = -66.982741, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1695399670, states[0] = -31.077566, states[40]= 0.000464
Saving checkpoint... 
Iteration: 1706927649, states[0] = -95.352495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1718457263, states[0] = 5.543030, states[40]= 0.005358
Saving checkpoint... 
Iteration: 1730013032, states[0] = -95.329839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742156141, states[0] = 6.148904, states[40]= 0.005397
Saving checkpoint... 
Iteration: 1754169715, states[0] = -2.202756, states[40]= 0.004417
Saving checkpoint... 
Iteration: 1766276619, states[0] = -95.254195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778324497, states[0] = -95.347951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790348402, states[0] = -95.378906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802319896, states[0] = -95.149119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814238613, states[0] = -95.049957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826247085, states[0] = -95.051377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838248452, states[0] = -95.043737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850302781, states[0] = -95.092487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862330384, states[0] = -95.105893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874390239, states[0] = -95.128759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885973903, states[0] = -95.145291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898147180, states[0] = -59.079497, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1909745601, states[0] = -95.018031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1921389156, states[0] = -95.121820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933186726, states[0] = -94.893378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945102885, states[0] = -15.432073, states[40]= 0.001398
Saving checkpoint... 
Iteration: 1956760991, states[0] = -95.035307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968382482, states[0] = -95.117773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980436285, states[0] = -95.132506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991994845, states[0] = -95.141980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004470382, states[0] = -95.138494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016127587, states[0] = -37.615284, states[40]= 0.000211
Saving checkpoint... 
Iteration: 2028115993, states[0] = -26.999866, states[40]= 0.000689
Saving checkpoint... 
Iteration: 2039725088, states[0] = -94.983198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051697096, states[0] = -94.929700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063320534, states[0] = -95.087154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075358948, states[0] = -95.107768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087348659, states[0] = -95.102959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099414198, states[0] = -95.126754, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.018086
 - CaMKt in component CaMK (millimolar): 0.007524
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.794936
 - nass in component intracellular_ions (millimolar): 6.794998
 - ki in component intracellular_ions (millimolar): 145.175604
 - kss in component intracellular_ions (millimolar): 145.175582
 - cansr in component intracellular_ions (millimolar): 1.338520
 - cajsr in component intracellular_ions (millimolar): 1.299157
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003576
 - hf in component INa (dimensionless): 0.882003
 - hs in component INa (dimensionless): 0.881998
 - j in component INa (dimensionless): 0.881970
 - hsp in component INa (dimensionless): 0.729614
 - jp in component INa (dimensionless): 0.881950
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.711024
 - hLp in component INaL (dimensionless): 0.449760
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.613154
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.686560
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927509
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999859
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001698
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.336680
 - xs1 in component IKs (dimensionless): 0.258199
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997306
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:30:59 (232973): called boinc_finish(0)

</stderr_txt>
]]>


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