𝕏

Task 54929477

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_595_1
Workunit 26082948
Created 27 Jun 2024, 4:00:51 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 1:07:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 29 min 18 sec
CPU time 1 hours 27 min 57 sec
Validate state Valid
Credit 60.01
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_595.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_595_1_r459129687_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_595_1_r459129687_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.905052
     * GNaL_b in INaL: 0.007155
     * Gto_b in Ito: 0.087273
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033882
     * GKs_b in IKs: 0.001844
     * GK1_b in IK1: 0.159717
     * Gncx_b in INaCa_i: 0.000951
     * Pnak_b in INaK: 67.575879
     * GKb_b in IKb: 0.003875
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.044691
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11948931, states[0] = -95.217951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23879669, states[0] = -95.172296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35869307, states[0] = -95.152102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47836214, states[0] = -95.126512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59789006, states[0] = -95.087135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71310887, states[0] = -95.099409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83228097, states[0] = -95.005892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95230443, states[0] = -95.007207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107099983, states[0] = -18.559837, states[40]= 0.001077
Saving checkpoint... 
Iteration: 119086197, states[0] = -6.199398, states[40]= 0.003138
Saving checkpoint... 
Iteration: 130998226, states[0] = -95.150030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142891278, states[0] = -95.127935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154803063, states[0] = -95.083276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166386286, states[0] = -95.125588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178248492, states[0] = -95.027933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190204248, states[0] = -94.954973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202028473, states[0] = 19.531208, states[40]= 0.006040
Saving checkpoint... 
Iteration: 213958526, states[0] = -95.142530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225904211, states[0] = -95.130458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237327879, states[0] = -95.098782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249225509, states[0] = -94.993418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261061501, states[0] = 7.616616, states[40]= 0.004795
Saving checkpoint... 
Iteration: 272999067, states[0] = -95.148049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284817156, states[0] = -95.092051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296481000, states[0] = -95.145740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308385358, states[0] = -95.124464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320362760, states[0] = -95.115962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332308284, states[0] = -95.085955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344217889, states[0] = -94.980213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355784573, states[0] = -95.066862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367336300, states[0] = -95.103335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379371441, states[0] = -95.119393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391281795, states[0] = -95.064283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403257526, states[0] = -95.038586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414821441, states[0] = -95.094670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426730456, states[0] = -95.001219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438560669, states[0] = 7.972119, states[40]= 0.004806
Saving checkpoint... 
Iteration: 450105112, states[0] = -23.230147, states[40]= 0.000794
Saving checkpoint... 
Iteration: 461644870, states[0] = -66.157022, states[40]= 0.000002
Saving checkpoint... 
Iteration: 473509879, states[0] = 23.022351, states[40]= 0.053524
Saving checkpoint... 
Iteration: 485445877, states[0] = -95.139878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497341374, states[0] = -95.105912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509267261, states[0] = -95.049595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521164633, states[0] = -93.414895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532759572, states[0] = -95.040917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544703034, states[0] = -94.951925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556238444, states[0] = -95.013238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568104063, states[0] = -22.229654, states[40]= 0.000842
Saving checkpoint... 
Iteration: 579907966, states[0] = -95.131121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591066180, states[0] = 5.546576, states[40]= 0.004713
Saving checkpoint... 
Iteration: 602975067, states[0] = -95.144672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614894052, states[0] = -95.127049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625551507, states[0] = 11.668145, states[40]= 0.004884
Saving checkpoint... 
Iteration: 637523393, states[0] = 20.781028, states[40]= 0.007280
Saving checkpoint... 
Iteration: 649036998, states[0] = 16.933842, states[40]= 0.005239
Saving checkpoint... 
Iteration: 660930529, states[0] = -95.136603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672854706, states[0] = -95.112210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684399496, states[0] = -95.128648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696136798, states[0] = -56.148911, states[40]= 0.000011
Saving checkpoint... 
Iteration: 708004083, states[0] = 30.741941, states[40]= 0.164509
Saving checkpoint... 
Iteration: 719549357, states[0] = 12.491223, states[40]= 0.004903
Saving checkpoint... 
Iteration: 731499812, states[0] = -95.147781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743025059, states[0] = 20.402487, states[40]= 0.006744
Saving checkpoint... 
Iteration: 754941182, states[0] = -95.138773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766827130, states[0] = -95.097877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778764113, states[0] = -95.045943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790665509, states[0] = -93.747039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802670052, states[0] = -94.599287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814553605, states[0] = 10.850779, states[40]= 0.004868
Saving checkpoint... 
Iteration: 826442335, states[0] = -95.138952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837929288, states[0] = -95.136205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849563398, states[0] = 6.794770, states[40]= 0.004767
Saving checkpoint... 
Iteration: 861131512, states[0] = -50.028966, states[40]= 0.000030
Saving checkpoint... 
Iteration: 872657824, states[0] = -86.801697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884557376, states[0] = 9.341064, states[40]= 0.004839
Saving checkpoint... 
Iteration: 896483911, states[0] = -95.145699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908420713, states[0] = -95.134164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920366275, states[0] = -95.116978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931916282, states[0] = -95.133054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943380382, states[0] = -95.122292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955321844, states[0] = -95.094542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967280608, states[0] = -95.062766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979172965, states[0] = -94.773300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991074715, states[0] = 1.307522, states[40]= 0.004387
Saving checkpoint... 
Iteration: 1003008319, states[0] = 23.627265, states[40]= 0.078113
Saving checkpoint... 
Iteration: 1014506279, states[0] = 25.407095, states[40]= 0.123980
Saving checkpoint... 
Iteration: 1026050042, states[0] = 12.230576, states[40]= 0.004897
Saving checkpoint... 
Iteration: 1038046812, states[0] = 13.448124, states[40]= 0.004935
Saving checkpoint... 
Iteration: 1049925651, states[0] = -95.135232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062049046, states[0] = 12.609202, states[40]= 0.004907
Saving checkpoint... 
Iteration: 1073984726, states[0] = -95.145683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085931224, states[0] = -95.136460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097864107, states[0] = -95.115969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109738619, states[0] = -95.013104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121695115, states[0] = -94.935122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133627897, states[0] = -45.982846, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1145595272, states[0] = -13.888059, states[40]= 0.001624
Saving checkpoint... 
Iteration: 1157491875, states[0] = -95.146540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169571013, states[0] = 3.235698, states[40]= 0.004566
Saving checkpoint... 
Iteration: 1181454708, states[0] = -95.141012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193082240, states[0] = -3.233647, states[40]= 0.003727
Saving checkpoint... 
Iteration: 1204902380, states[0] = -95.129124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216792268, states[0] = -95.072956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228692483, states[0] = -94.929327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240561011, states[0] = 7.827037, states[40]= 0.004802
Saving checkpoint... 
Iteration: 1252088692, states[0] = -8.065660, states[40]= 0.002736
Saving checkpoint... 
Iteration: 1263561319, states[0] = 7.695678, states[40]= 0.004798
Saving checkpoint... 
Iteration: 1275480884, states[0] = -95.145025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286989770, states[0] = -95.146187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298593376, states[0] = -12.142226, states[40]= 0.001916
Saving checkpoint... 
Iteration: 1310125450, states[0] = -43.328294, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1321998555, states[0] = -95.147225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333508081, states[0] = 23.759889, states[40]= 0.082697
Saving checkpoint... 
Iteration: 1345611137, states[0] = -28.995501, states[40]= 0.000526
Saving checkpoint... 
Iteration: 1357131216, states[0] = -49.692522, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1368662166, states[0] = -91.951111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379786375, states[0] = -95.067758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391671726, states[0] = -94.716623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403145693, states[0] = -67.265856, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1414663879, states[0] = -93.058004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426573924, states[0] = 1.733347, states[40]= 0.004432
Saving checkpoint... 
Iteration: 1438481814, states[0] = -95.145038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450358617, states[0] = -95.113399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462217619, states[0] = -94.978943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473652483, states[0] = -77.634281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485579352, states[0] = -1.371811, states[40]= 0.004039
Saving checkpoint... 
Iteration: 1497112799, states[0] = -30.598300, states[40]= 0.000450
Saving checkpoint... 
Iteration: 1508987991, states[0] = -95.372984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520822871, states[0] = -63.691238, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1532687194, states[0] = -95.399047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1544618732, states[0] = -95.334373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556149564, states[0] = 8.311211, states[40]= 0.005572
Saving checkpoint... 
Iteration: 1567567143, states[0] = -2.777454, states[40]= 0.004305
Saving checkpoint... 
Iteration: 1579473379, states[0] = -95.410735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590967188, states[0] = -2.971096, states[40]= 0.004269
Saving checkpoint... 
Iteration: 1602855992, states[0] = -95.398230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614721519, states[0] = -64.867202, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1626165926, states[0] = -95.242625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637591589, states[0] = -95.304829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649445367, states[0] = 10.265155, states[40]= 0.005724
Saving checkpoint... 
Iteration: 1660990884, states[0] = -95.303883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672938571, states[0] = -92.196338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684859681, states[0] = 2.214182, states[40]= 0.005085
Saving checkpoint... 
Iteration: 1696369938, states[0] = -95.254895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708295198, states[0] = -32.271111, states[40]= 0.000368
Saving checkpoint... 
Iteration: 1719955698, states[0] = 4.641208, states[40]= 0.005320
Saving checkpoint... 
Iteration: 1731640611, states[0] = 12.607770, states[40]= 0.005934
Saving checkpoint... 
Iteration: 1743193553, states[0] = -95.309775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755177276, states[0] = -95.273523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767066836, states[0] = -2.833125, states[40]= 0.004300
Saving checkpoint... 
Iteration: 1779003446, states[0] = 34.814325, states[40]= 0.134487
Saving checkpoint... 
Iteration: 1790932058, states[0] = -95.373467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1802417953, states[0] = -95.199886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814336732, states[0] = -95.151150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826184742, states[0] = -94.945465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838107105, states[0] = -26.571102, states[40]= 0.000640
Saving checkpoint... 
Iteration: 1849910206, states[0] = -95.148803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861356718, states[0] = -95.125138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873235744, states[0] = -95.017553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884652852, states[0] = -79.052890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896179597, states[0] = -94.892745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908072993, states[0] = 2.136737, states[40]= 0.004474
Saving checkpoint... 
Iteration: 1919995479, states[0] = -95.148733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931376070, states[0] = -95.121677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943229536, states[0] = -94.999855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1955168194, states[0] = -94.386514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967070851, states[0] = 3.301709, states[40]= 0.004572
Saving checkpoint... 
Iteration: 1978989343, states[0] = -95.146012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990515465, states[0] = 22.131942, states[40]= 0.016373
Saving checkpoint... 
Iteration: 2002449957, states[0] = -95.139735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013966497, states[0] = -95.142481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025477271, states[0] = -95.144041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037422403, states[0] = -95.133793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049193243, states[0] = -94.930409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060744725, states[0] = -95.021015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072679271, states[0] = -94.884352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084601319, states[0] = -19.612970, states[40]= 0.000996
Saving checkpoint... 
Iteration: 2096425592, states[0] = -95.134434, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.022669
 - CaMKt in component CaMK (millimolar): 0.007186
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.619691
 - nass in component intracellular_ions (millimolar): 6.619753
 - ki in component intracellular_ions (millimolar): 145.354531
 - kss in component intracellular_ions (millimolar): 145.354510
 - cansr in component intracellular_ions (millimolar): 1.324242
 - cajsr in component intracellular_ions (millimolar): 1.285916
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003575
 - hf in component INa (dimensionless): 0.882081
 - hs in component INa (dimensionless): 0.882077
 - j in component INa (dimensionless): 0.882049
 - hsp in component INa (dimensionless): 0.729763
 - jp in component INa (dimensionless): 0.882030
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.713137
 - hLp in component INaL (dimensionless): 0.455723
 - a in component Ito (dimensionless): 0.000618
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.621693
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.696687
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933711
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001650
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326931
 - xs1 in component IKs (dimensionless): 0.244721
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997305
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:35:13 (232450): called boinc_finish(0)

</stderr_txt>
]]>


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