𝕏

Task 54929471

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_886_1
Workunit 26082945
Created 27 Jun 2024, 4:00:51 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 30 Jun 2024, 14:05:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 55 sec
CPU time 1 hours 27 min 31 sec
Validate state Valid
Credit 60.53
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_886.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_886_1_r982378605_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_886_1_r982378605_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 121.187281
     * GNaL_b in INaL: 0.006466
     * Gto_b in Ito: 0.086981
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033745
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.143629
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 66.628312
     * GKb_b in IKb: 0.003849
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.050921
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11541985, states[0] = 13.213705, states[40]= 0.005232
Saving checkpoint... 
Iteration: 22760047, states[0] = -94.895819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34686395, states[0] = -94.747925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46624611, states[0] = -48.803815, states[40]= 0.000033
Saving checkpoint... 
Iteration: 58543988, states[0] = 13.147946, states[40]= 0.005163
Saving checkpoint... 
Iteration: 70435624, states[0] = -94.954330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82326711, states[0] = -94.909535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94267561, states[0] = -94.857212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105827637, states[0] = -94.905932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117796299, states[0] = -94.882210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129284747, states[0] = -94.871090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141257379, states[0] = -94.840647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153263093, states[0] = -94.847129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165281191, states[0] = -94.866257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177224223, states[0] = -94.790294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189226612, states[0] = -94.794248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201197315, states[0] = -94.737269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213218175, states[0] = -94.779066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225273896, states[0] = -94.858185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237307232, states[0] = -94.887887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249283957, states[0] = -94.868176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261324250, states[0] = -94.899542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273303174, states[0] = -94.884700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285376911, states[0] = -94.925451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297184743, states[0] = -94.705871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309096033, states[0] = -18.487884, states[40]= 0.001078
Saving checkpoint... 
Iteration: 321107145, states[0] = -29.426058, states[40]= 0.000474
Saving checkpoint... 
Iteration: 332314559, states[0] = -94.893031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343947480, states[0] = -94.944741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355922183, states[0] = -94.939239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367937879, states[0] = -94.942794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379535244, states[0] = 16.566392, states[40]= 0.005633
Saving checkpoint... 
Iteration: 391174963, states[0] = -94.632413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403111700, states[0] = -33.945273, states[40]= 0.000286
Saving checkpoint... 
Iteration: 415212620, states[0] = -94.768258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427129166, states[0] = -52.468557, states[40]= 0.000018
Saving checkpoint... 
Iteration: 438757794, states[0] = -94.839446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450760443, states[0] = -94.842694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462354980, states[0] = -94.916105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474352570, states[0] = -94.914960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486271955, states[0] = -94.855823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497873274, states[0] = -94.923901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509834890, states[0] = -94.905719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521842944, states[0] = -94.910110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533466769, states[0] = -94.947999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545421577, states[0] = -94.938971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557388151, states[0] = -94.929279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569049297, states[0] = 11.284612, states[40]= 0.005026
Saving checkpoint... 
Iteration: 581054753, states[0] = 9.051169, states[40]= 0.004933
Saving checkpoint... 
Iteration: 593053975, states[0] = 9.376508, states[40]= 0.004945
Saving checkpoint... 
Iteration: 605054817, states[0] = 9.024299, states[40]= 0.004932
Saving checkpoint... 
Iteration: 617025345, states[0] = 19.618529, states[40]= 0.007205
Saving checkpoint... 
Iteration: 628574497, states[0] = -0.605252, states[40]= 0.004192
Saving checkpoint... 
Iteration: 640115674, states[0] = -37.950309, states[40]= 0.000167
Saving checkpoint... 
Iteration: 652092945, states[0] = -15.464165, states[40]= 0.001411
Saving checkpoint... 
Iteration: 664066614, states[0] = 3.680003, states[40]= 0.004654
Saving checkpoint... 
Iteration: 676212772, states[0] = -94.768390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687705068, states[0] = -94.753047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699231440, states[0] = -94.801596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710839794, states[0] = -94.908316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722766043, states[0] = -94.849120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734738850, states[0] = -94.813208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746349727, states[0] = -94.913417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758256898, states[0] = -94.838129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770163139, states[0] = -93.270975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782056630, states[0] = 8.255556, states[40]= 0.004902
Saving checkpoint... 
Iteration: 793602089, states[0] = -24.444842, states[40]= 0.000708
Saving checkpoint... 
Iteration: 804754338, states[0] = -94.834839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816752595, states[0] = -94.832561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828383352, states[0] = -94.927452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840395875, states[0] = -94.931627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852505849, states[0] = 26.722620, states[40]= 0.132094
Saving checkpoint... 
Iteration: 864071009, states[0] = 1.393539, states[40]= 0.004443
Saving checkpoint... 
Iteration: 876045000, states[0] = 12.973851, states[40]= 0.005130
Saving checkpoint... 
Iteration: 888058262, states[0] = 7.550255, states[40]= 0.004873
Saving checkpoint... 
Iteration: 899678070, states[0] = -94.670953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911726294, states[0] = -94.792874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923657326, states[0] = -89.163769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935228914, states[0] = -94.797287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947216385, states[0] = -94.775095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958828946, states[0] = -94.901966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970822036, states[0] = -94.897648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982402344, states[0] = -94.933513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994287178, states[0] = -94.870663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006234704, states[0] = -94.806638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018135532, states[0] = -59.672120, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1030028153, states[0] = 18.835047, states[40]= 0.006532
Saving checkpoint... 
Iteration: 1041594477, states[0] = -16.959509, states[40]= 0.001230
Saving checkpoint... 
Iteration: 1053639582, states[0] = -64.419430, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1065531943, states[0] = 17.668740, states[40]= 0.005960
Saving checkpoint... 
Iteration: 1077080122, states[0] = -4.311059, states[40]= 0.003556
Saving checkpoint... 
Iteration: 1088677509, states[0] = -94.665651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100608306, states[0] = -30.572995, states[40]= 0.000422
Saving checkpoint... 
Iteration: 1112535962, states[0] = 16.317657, states[40]= 0.005576
Saving checkpoint... 
Iteration: 1124498323, states[0] = -94.951961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136395576, states[0] = -94.931353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147993517, states[0] = -94.951373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159973764, states[0] = -94.948694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171564156, states[0] = 4.872993, states[40]= 0.004737
Saving checkpoint... 
Iteration: 1183591375, states[0] = -13.946902, states[40]= 0.001631
Saving checkpoint... 
Iteration: 1195167842, states[0] = -94.276578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206797897, states[0] = -94.879864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218801825, states[0] = -94.883028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230341698, states[0] = -94.909020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242381214, states[0] = -94.926433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253875391, states[0] = -94.924259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265763345, states[0] = -94.845659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277334347, states[0] = -94.904941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289073943, states[0] = -0.274487, states[40]= 0.004238
Saving checkpoint... 
Iteration: 1301049764, states[0] = 11.097686, states[40]= 0.005017
Saving checkpoint... 
Iteration: 1313014220, states[0] = 21.984996, states[40]= 0.022242
Saving checkpoint... 
Iteration: 1325057146, states[0] = 8.034094, states[40]= 0.004893
Saving checkpoint... 
Iteration: 1336681256, states[0] = -94.691479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348219909, states[0] = -94.781348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360157942, states[0] = -89.822613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372186013, states[0] = -94.709095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384158145, states[0] = -90.027489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396071449, states[0] = 1.151692, states[40]= 0.004416
Saving checkpoint... 
Iteration: 1408042070, states[0] = 14.093490, states[40]= 0.005231
Saving checkpoint... 
Iteration: 1419633323, states[0] = -57.150930, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1431563181, states[0] = 5.332288, states[40]= 0.004765
Saving checkpoint... 
Iteration: 1443576269, states[0] = -1.700226, states[40]= 0.004026
Saving checkpoint... 
Iteration: 1455556932, states[0] = 8.126171, states[40]= 0.004897
Saving checkpoint... 
Iteration: 1467608936, states[0] = -31.196600, states[40]= 0.000395
Saving checkpoint... 
Iteration: 1479195799, states[0] = -94.732893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490834417, states[0] = -94.904851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502795912, states[0] = -32.841277, states[40]= 0.000307
Saving checkpoint... 
Iteration: 1514637329, states[0] = -95.169220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526219299, states[0] = -63.467101, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1538203943, states[0] = -44.942032, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1550156311, states[0] = 3.220267, states[40]= 0.005227
Saving checkpoint... 
Iteration: 1561703814, states[0] = -95.159553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573231191, states[0] = 16.248043, states[40]= 0.007036
Saving checkpoint... 
Iteration: 1585197957, states[0] = -95.277575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597098251, states[0] = -95.158122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609067611, states[0] = -95.086592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621215884, states[0] = 21.771106, states[40]= 0.018323
Saving checkpoint... 
Iteration: 1632858866, states[0] = -95.249955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644749469, states[0] = -94.935758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656793266, states[0] = -95.151599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668384999, states[0] = -24.511226, states[40]= 0.000725
Saving checkpoint... 
Iteration: 1679991240, states[0] = -95.278977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691953498, states[0] = -95.245429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703490434, states[0] = -30.672815, states[40]= 0.000416
Saving checkpoint... 
Iteration: 1715498873, states[0] = -40.338952, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1727040301, states[0] = -95.230084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739037497, states[0] = -95.226509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751060774, states[0] = -95.253163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763076200, states[0] = -95.267413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775135944, states[0] = 13.968453, states[40]= 0.006465
Saving checkpoint... 
Iteration: 1787035278, states[0] = -95.223587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799073657, states[0] = -95.265211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811089861, states[0] = -15.588278, states[40]= 0.001428
Saving checkpoint... 
Iteration: 1823068508, states[0] = 1.698054, states[40]= 0.004520
Saving checkpoint... 
Iteration: 1835187102, states[0] = -94.745314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846651116, states[0] = -82.489003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858524022, states[0] = 19.820037, states[40]= 0.007622
Saving checkpoint... 
Iteration: 1870411277, states[0] = -94.947215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882362089, states[0] = -94.926707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894282466, states[0] = -94.871553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905824382, states[0] = -94.902739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917706804, states[0] = -94.758816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929586717, states[0] = -9.713351, states[40]= 0.002414
Saving checkpoint... 
Iteration: 1941398023, states[0] = -94.933070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952988865, states[0] = -94.951318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964978450, states[0] = -94.949589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976961446, states[0] = -94.946731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988527959, states[0] = 18.888087, states[40]= 0.006570
Saving checkpoint... 
Iteration: 2000010631, states[0] = 22.785241, states[40]= 0.047372
Saving checkpoint... 
Iteration: 2011984176, states[0] = -94.949788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024014266, states[0] = 21.975899, states[40]= 0.022051
Saving checkpoint... 
Iteration: 2035514696, states[0] = 21.898545, states[40]= 0.020389
Saving checkpoint... 
Iteration: 2047433935, states[0] = -94.940937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058906728, states[0] = -94.934121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070860877, states[0] = -94.917777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082873455, states[0] = -94.922975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094698209, states[0] = -94.737729, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.827397
 - CaMKt in component CaMK (millimolar): 0.006861
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.691077
 - nass in component intracellular_ions (millimolar): 6.691136
 - ki in component intracellular_ions (millimolar): 145.287953
 - kss in component intracellular_ions (millimolar): 145.287932
 - cansr in component intracellular_ions (millimolar): 1.306652
 - cajsr in component intracellular_ions (millimolar): 1.269181
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003646
 - hf in component INa (dimensionless): 0.878703
 - hs in component INa (dimensionless): 0.878698
 - j in component INa (dimensionless): 0.878669
 - hsp in component INa (dimensionless): 0.723389
 - jp in component INa (dimensionless): 0.878649
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708709
 - hLp in component INaL (dimensionless): 0.451979
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.624718
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.700072
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937921
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001580
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333936
 - xs1 in component IKs (dimensionless): 0.235425
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997357
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:04:51 (237439): called boinc_finish(0)

</stderr_txt>
]]>


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