𝕏

Task 54929467

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_186_1
Workunit 26082943
Created 27 Jun 2024, 4:00:51 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 30 Jun 2024, 14:05:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 57 sec
CPU time 1 hours 27 min 38 sec
Validate state Valid
Credit 60.35
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_186.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_186_1_r674432881_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_186_1_r674432881_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.415234
     * GNaL_b in INaL: 0.008121
     * Gto_b in Ito: 0.071419
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033867
     * GKs_b in IKs: 0.001815
     * GK1_b in IK1: 0.164983
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 61.441419
     * GKb_b in IKb: 0.004040
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.049619
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11952515, states[0] = -95.057222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23551971, states[0] = 11.122928, states[40]= 0.005152
Saving checkpoint... 
Iteration: 35538331, states[0] = 16.614883, states[40]= 0.005639
Saving checkpoint... 
Iteration: 46728703, states[0] = -94.910727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58509652, states[0] = 25.333860, states[40]= 0.056456
Saving checkpoint... 
Iteration: 70366226, states[0] = -95.014364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82355795, states[0] = -95.009344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93955478, states[0] = -95.034611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105956526, states[0] = -95.034255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117636944, states[0] = -57.894385, states[40]= 0.000008
Saving checkpoint... 
Iteration: 129545871, states[0] = 13.836082, states[40]= 0.005302
Saving checkpoint... 
Iteration: 141119771, states[0] = -38.525183, states[40]= 0.000166
Saving checkpoint... 
Iteration: 153108789, states[0] = -27.786108, states[40]= 0.000588
Saving checkpoint... 
Iteration: 165057915, states[0] = 8.872131, states[40]= 0.005055
Saving checkpoint... 
Iteration: 177044403, states[0] = 14.424816, states[40]= 0.005349
Saving checkpoint... 
Iteration: 188954487, states[0] = -95.032742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200887998, states[0] = -95.018062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212768550, states[0] = -94.950959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224727345, states[0] = -94.901494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236604444, states[0] = -23.628548, states[40]= 0.000786
Saving checkpoint... 
Iteration: 248511050, states[0] = 24.813370, states[40]= 0.041347
Saving checkpoint... 
Iteration: 260520709, states[0] = 22.417648, states[40]= 0.009738
Saving checkpoint... 
Iteration: 271846161, states[0] = -95.002696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283912732, states[0] = -95.024474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295551107, states[0] = 11.735873, states[40]= 0.005177
Saving checkpoint... 
Iteration: 307126243, states[0] = -45.338365, states[40]= 0.000061
Saving checkpoint... 
Iteration: 319118313, states[0] = -37.023972, states[40]= 0.000204
Saving checkpoint... 
Iteration: 331081057, states[0] = -3.171002, states[40]= 0.003824
Saving checkpoint... 
Iteration: 342641425, states[0] = -63.456069, states[40]= 0.000003
Saving checkpoint... 
Iteration: 354601954, states[0] = -21.259420, states[40]= 0.000907
Saving checkpoint... 
Iteration: 366553226, states[0] = 10.861882, states[40]= 0.005138
Saving checkpoint... 
Iteration: 378591615, states[0] = -11.551568, states[40]= 0.002064
Saving checkpoint... 
Iteration: 390093606, states[0] = -13.369473, states[40]= 0.001739
Saving checkpoint... 
Iteration: 402075128, states[0] = 0.500756, states[40]= 0.004411
Saving checkpoint... 
Iteration: 413754393, states[0] = -94.936074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425634466, states[0] = -54.820217, states[40]= 0.000014
Saving checkpoint... 
Iteration: 437550916, states[0] = 11.814192, states[40]= 0.005181
Saving checkpoint... 
Iteration: 449528932, states[0] = 20.046435, states[40]= 0.006661
Saving checkpoint... 
Iteration: 461026895, states[0] = 20.684955, states[40]= 0.007080
Saving checkpoint... 
Iteration: 472959591, states[0] = -95.033244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484828342, states[0] = -94.993939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496768141, states[0] = -94.950335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508623216, states[0] = -42.063371, states[40]= 0.000100
Saving checkpoint... 
Iteration: 520234315, states[0] = -94.911142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532195753, states[0] = -94.848204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544055087, states[0] = 10.083252, states[40]= 0.005105
Saving checkpoint... 
Iteration: 556024184, states[0] = 21.484002, states[40]= 0.007884
Saving checkpoint... 
Iteration: 567870703, states[0] = -95.012189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579405670, states[0] = -95.022580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591313608, states[0] = -94.985513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603269585, states[0] = -94.951662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614705338, states[0] = -94.865630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626617708, states[0] = -36.420059, states[40]= 0.000222
Saving checkpoint... 
Iteration: 638562898, states[0] = 6.668525, states[40]= 0.004950
Saving checkpoint... 
Iteration: 650538255, states[0] = 16.788089, states[40]= 0.005643
Saving checkpoint... 
Iteration: 662013091, states[0] = 24.224214, states[40]= 0.027049
Saving checkpoint... 
Iteration: 673835818, states[0] = -94.997630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685658976, states[0] = -90.693181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697245161, states[0] = -94.925100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709098947, states[0] = -18.399068, states[40]= 0.001109
Saving checkpoint... 
Iteration: 720637116, states[0] = -58.023141, states[40]= 0.000008
Saving checkpoint... 
Iteration: 732630529, states[0] = -50.189158, states[40]= 0.000029
Saving checkpoint... 
Iteration: 744676432, states[0] = -94.792874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756661558, states[0] = -92.777735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768681731, states[0] = -94.818035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780716796, states[0] = -94.884901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792322393, states[0] = -94.990530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804284107, states[0] = -94.964423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816297227, states[0] = -94.974515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827862234, states[0] = -95.008953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839446546, states[0] = -95.030938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851490101, states[0] = -95.037014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863486495, states[0] = -95.036594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875488260, states[0] = -95.036791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887497822, states[0] = -95.037830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899360518, states[0] = -95.008256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910874078, states[0] = -95.013150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922951033, states[0] = -95.031639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934996278, states[0] = -95.037640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947006070, states[0] = 28.624660, states[40]= 0.120242
Saving checkpoint... 
Iteration: 958995133, states[0] = -95.037504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971011545, states[0] = 24.653619, states[40]= 0.037148
Saving checkpoint... 
Iteration: 982965757, states[0] = -95.033851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994573467, states[0] = 1.428537, states[40]= 0.004525
Saving checkpoint... 
Iteration: 1006075651, states[0] = 0.200878, states[40]= 0.004371
Saving checkpoint... 
Iteration: 1017610795, states[0] = -29.685854, states[40]= 0.000495
Saving checkpoint... 
Iteration: 1029636498, states[0] = -57.268746, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1041670000, states[0] = -94.653978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053704653, states[0] = -94.864161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065739280, states[0] = -94.917451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077769084, states[0] = -94.950906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089754676, states[0] = -94.935995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101757803, states[0] = -94.939413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113227735, states[0] = -94.901499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125155799, states[0] = -86.369694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137139310, states[0] = -60.744660, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1149106631, states[0] = -25.706670, states[40]= 0.000688
Saving checkpoint... 
Iteration: 1161039560, states[0] = 16.298060, states[40]= 0.005564
Saving checkpoint... 
Iteration: 1172937720, states[0] = -95.029174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184881707, states[0] = -95.015482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196468781, states[0] = -95.034151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208066462, states[0] = 5.003738, states[40]= 0.004848
Saving checkpoint... 
Iteration: 1219573239, states[0] = 1.553102, states[40]= 0.004539
Saving checkpoint... 
Iteration: 1231559267, states[0] = 8.289597, states[40]= 0.005029
Saving checkpoint... 
Iteration: 1243205378, states[0] = -94.865333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255087092, states[0] = -7.661244, states[40]= 0.002880
Saving checkpoint... 
Iteration: 1267051840, states[0] = 11.435194, states[40]= 0.005163
Saving checkpoint... 
Iteration: 1278979382, states[0] = -95.035495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290725463, states[0] = -94.898046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302715536, states[0] = -94.882554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314646767, states[0] = -70.941006, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1326618826, states[0] = -37.537700, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1338612018, states[0] = -30.861918, states[40]= 0.000439
Saving checkpoint... 
Iteration: 1350180820, states[0] = -94.814806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361804175, states[0] = -94.979026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373789546, states[0] = -94.968442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385819449, states[0] = -94.988514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397807979, states[0] = -94.981509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409821232, states[0] = -94.989517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421395885, states[0] = -95.019520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432941631, states[0] = -95.029735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444807788, states[0] = -94.981358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456407510, states[0] = -95.022528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468418474, states[0] = -95.025089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479866793, states[0] = -95.010266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491711551, states[0] = -94.875839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503213278, states[0] = -95.178774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514742009, states[0] = 12.796399, states[40]= 0.006202
Saving checkpoint... 
Iteration: 1526265553, states[0] = -95.108025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538158575, states[0] = 3.287990, states[40]= 0.005324
Saving checkpoint... 
Iteration: 1550099683, states[0] = -95.300144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561638084, states[0] = -91.719417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573474855, states[0] = -95.291709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585474955, states[0] = -95.294151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1597413660, states[0] = -95.229712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1609437332, states[0] = -95.261771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621581508, states[0] = -17.428677, states[40]= 0.001337
Saving checkpoint... 
Iteration: 1633154288, states[0] = -95.280681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645074794, states[0] = -95.160646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656602015, states[0] = 46.088436, states[40]= 0.073271
Saving checkpoint... 
Iteration: 1668633855, states[0] = 16.092689, states[40]= 0.006927
Saving checkpoint... 
Iteration: 1680195693, states[0] = -95.203445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1692188449, states[0] = -95.189877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704184795, states[0] = -95.182642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716024884, states[0] = 20.023333, states[40]= 0.008747
Saving checkpoint... 
Iteration: 1727936362, states[0] = -95.262976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739905550, states[0] = -95.220560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751410060, states[0] = 25.685325, states[40]= 0.051775
Saving checkpoint... 
Iteration: 1762980555, states[0] = -95.173904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774851422, states[0] = 7.018883, states[40]= 0.005719
Saving checkpoint... 
Iteration: 1786432937, states[0] = -95.258954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797923121, states[0] = 20.723164, states[40]= 0.009481
Saving checkpoint... 
Iteration: 1809411586, states[0] = -95.072321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820931058, states[0] = -95.064742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832976697, states[0] = -95.061667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844961234, states[0] = -95.051791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856871049, states[0] = -95.025141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868371187, states[0] = -95.021365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880325913, states[0] = -94.998775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891833320, states[0] = -95.000669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903830409, states[0] = -94.997724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915804232, states[0] = -94.981246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927712141, states[0] = -94.878369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939688165, states[0] = -94.833870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951161437, states[0] = -92.749034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963103787, states[0] = -23.041992, states[40]= 0.000814
Saving checkpoint... 
Iteration: 1974637729, states[0] = -58.818688, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1986609264, states[0] = -28.240037, states[40]= 0.000566
Saving checkpoint... 
Iteration: 1998525848, states[0] = 20.998008, states[40]= 0.007348
Saving checkpoint... 
Iteration: 2010371795, states[0] = -95.011848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021937721, states[0] = -95.028750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033869559, states[0] = -95.010967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045789189, states[0] = -94.967779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057334149, states[0] = -94.995989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069226373, states[0] = -94.898917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080770390, states[0] = -94.951532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092785062, states[0] = -94.964413, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.913182
 - CaMKt in component CaMK (millimolar): 0.006901
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.871708
 - nass in component intracellular_ions (millimolar): 6.871767
 - ki in component intracellular_ions (millimolar): 145.106785
 - kss in component intracellular_ions (millimolar): 145.106764
 - cansr in component intracellular_ions (millimolar): 1.310494
 - cajsr in component intracellular_ions (millimolar): 1.272805
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880197
 - hs in component INa (dimensionless): 0.880193
 - j in component INa (dimensionless): 0.880168
 - hsp in component INa (dimensionless): 0.726204
 - jp in component INa (dimensionless): 0.880151
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710796
 - hLp in component INaL (dimensionless): 0.454068
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622500
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697154
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932689
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999879
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339413
 - xs1 in component IKs (dimensionless): 0.243166
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:04:56 (237443): called boinc_finish(0)

</stderr_txt>
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