Task 54929463

Name	HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_580_1
Workunit	26082941
Created	27 Jun 2024, 4:00:51 UTC
Sent	27 Jun 2024, 5:23:34 UTC
Report deadline	30 Jun 2024, 14:59:34 UTC
Received	28 Jun 2024, 5:41:52 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	237767
Run time	1 hours 28 min 50 sec
CPU time	1 hours 27 min 28 sec
Validate state	Valid
Credit	58.57
Device peak FLOPS	4.40 GFLOPS
Application version	Human ventricular cell models optimization v0.02 x86_64-pc-linux-gnu
Peak working set size	2.50 MB
Peak swap size	3.82 MB
Peak disk usage	0.29 MB
Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_580.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_580_1_r1774686242_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_580_1_r1774686242_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 122.039347
     * GNaL_b in INaL: 0.006848
     * Gto_b in Ito: 0.078800
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032711
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.142869
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 66.859802
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.052417
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11975493, states[0] = -95.122887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23554819, states[0] = 8.982010, states[40]= 0.005049
Saving checkpoint... 
Iteration: 35500716, states[0] = 45.615120, states[40]= 0.007056
Saving checkpoint... 
Iteration: 47465905, states[0] = -95.059358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59384251, states[0] = -95.030885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71016382, states[0] = 22.647472, states[40]= 0.016214
Saving checkpoint... 
Iteration: 82945413, states[0] = -95.037066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95063384, states[0] = 6.067427, states[40]= 0.004875
Saving checkpoint... 
Iteration: 106565910, states[0] = 4.928236, states[40]= 0.004801
Saving checkpoint... 
Iteration: 118167047, states[0] = -93.870952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130181572, states[0] = -94.773835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141792813, states[0] = -94.960672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153376397, states[0] = -95.008979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164954977, states[0] = -95.029514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176931606, states[0] = -95.024529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187353526, states[0] = -94.998432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199306841, states[0] = -94.970352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210934811, states[0] = -95.024779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222290243, states[0] = -94.956644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234117121, states[0] = -36.753536, states[40]= 0.000202
Saving checkpoint... 
Iteration: 245653709, states[0] = -80.494659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257833773, states[0] = -94.987669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269490677, states[0] = -95.033932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281513076, states[0] = 23.480881, states[40]= 0.028649
Saving checkpoint... 
Iteration: 293539254, states[0] = 16.026689, states[40]= 0.005568
Saving checkpoint... 
Iteration: 305533103, states[0] = 18.199865, states[40]= 0.006108
Saving checkpoint... 
Iteration: 317561355, states[0] = 7.116688, states[40]= 0.004926
Saving checkpoint... 
Iteration: 329590954, states[0] = -11.385654, states[40]= 0.002081
Saving checkpoint... 
Iteration: 341533790, states[0] = 17.967440, states[40]= 0.006030
Saving checkpoint... 
Iteration: 353594400, states[0] = -14.597883, states[40]= 0.001535
Saving checkpoint... 
Iteration: 365627252, states[0] = -47.382977, states[40]= 0.000042
Saving checkpoint... 
Iteration: 377666998, states[0] = -93.793773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389268472, states[0] = -94.934772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401273563, states[0] = -94.940255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413326073, states[0] = -94.982941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424964405, states[0] = -95.029997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436968449, states[0] = -95.030640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448556154, states[0] = 9.359673, states[40]= 0.005030
Saving checkpoint... 
Iteration: 460618940, states[0] = -38.584667, states[40]= 0.000156
Saving checkpoint... 
Iteration: 472641450, states[0] = -63.560905, states[40]= 0.000003
Saving checkpoint... 
Iteration: 484652092, states[0] = -77.954957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496688960, states[0] = -94.801127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508310902, states[0] = -94.972784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520365885, states[0] = -95.003217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531985139, states[0] = -95.033018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543620461, states[0] = -40.143258, states[40]= 0.000125
Saving checkpoint... 
Iteration: 555178559, states[0] = -94.740934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567173645, states[0] = -94.613789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578980918, states[0] = -95.032415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590797290, states[0] = -94.962266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602838193, states[0] = -94.989886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614480808, states[0] = -95.032381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626115650, states[0] = -35.274713, states[40]= 0.000246
Saving checkpoint... 
Iteration: 638153913, states[0] = -80.805676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650179037, states[0] = -94.746890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662170738, states[0] = -94.414874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674202788, states[0] = -94.832246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686144567, states[0] = -67.402315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697721009, states[0] = -94.867111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709724792, states[0] = -94.873706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721709136, states[0] = -94.844934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733621010, states[0] = -40.711040, states[40]= 0.000115
Saving checkpoint... 
Iteration: 745210937, states[0] = -94.848421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756786251, states[0] = -94.952554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768748268, states[0] = -94.909707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780642167, states[0] = -64.425992, states[40]= 0.000002
Saving checkpoint... 
Iteration: 792590108, states[0] = -10.622082, states[40]= 0.002231
Saving checkpoint... 
Iteration: 804188997, states[0] = -94.801062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815794762, states[0] = -94.960037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827765771, states[0] = -94.931503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839824232, states[0] = -94.981565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851828235, states[0] = -94.984025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863847764, states[0] = -94.994748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875813457, states[0] = -94.974398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887859107, states[0] = -95.000090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899880338, states[0] = -95.008659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911884304, states[0] = -95.010069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923440790, states[0] = -95.025391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935004815, states[0] = 31.096211, states[40]= 0.137402
Saving checkpoint... 
Iteration: 946524147, states[0] = 20.922500, states[40]= 0.008084
Saving checkpoint... 
Iteration: 958610664, states[0] = -30.359355, states[40]= 0.000443
Saving checkpoint... 
Iteration: 970777999, states[0] = -94.944501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982645263, states[0] = -68.292761, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994685943, states[0] = -94.791464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006719208, states[0] = -94.863722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018727953, states[0] = -94.878882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030744807, states[0] = -94.904768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042662574, states[0] = -91.776940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054253182, states[0] = -94.916083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066175232, states[0] = -94.672647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077759124, states[0] = -94.923539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089751480, states[0] = -94.913840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101351161, states[0] = -94.996287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113277720, states[0] = -94.944144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124897901, states[0] = -95.014427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136475745, states[0] = -95.031376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147999211, states[0] = -95.034451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159946485, states[0] = -95.026402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171974562, states[0] = -95.031182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183976197, states[0] = -95.031417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195954325, states[0] = -95.027851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208015380, states[0] = 22.964600, states[40]= 0.018972
Saving checkpoint... 
Iteration: 1220017685, states[0] = 22.473049, states[40]= 0.013679
Saving checkpoint... 
Iteration: 1231554716, states[0] = 9.960060, states[40]= 0.005056
Saving checkpoint... 
Iteration: 1243553958, states[0] = 10.273531, states[40]= 0.005070
Saving checkpoint... 
Iteration: 1255179819, states[0] = -94.755086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267161692, states[0] = -91.094958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279065456, states[0] = 5.247040, states[40]= 0.004817
Saving checkpoint... 
Iteration: 1291068092, states[0] = 3.982488, states[40]= 0.004726
Saving checkpoint... 
Iteration: 1303096493, states[0] = -16.601760, states[40]= 0.001275
Saving checkpoint... 
Iteration: 1315146466, states[0] = -69.867220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327111717, states[0] = -31.390751, states[40]= 0.000396
Saving checkpoint... 
Iteration: 1338715864, states[0] = -94.857427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350223366, states[0] = -94.870899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362162958, states[0] = -92.038934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374091446, states[0] = -11.833912, states[40]= 0.001996
Saving checkpoint... 
Iteration: 1386085413, states[0] = -6.654278, states[40]= 0.003077
Saving checkpoint... 
Iteration: 1397610549, states[0] = -30.246637, states[40]= 0.000448
Saving checkpoint... 
Iteration: 1409135463, states[0] = -56.590201, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1421130155, states[0] = -50.599955, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1433135480, states[0] = -56.609562, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1445107242, states[0] = -27.021637, states[40]= 0.000601
Saving checkpoint... 
Iteration: 1456991239, states[0] = -95.033317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468520068, states[0] = 21.940321, states[40]= 0.010642
Saving checkpoint... 
Iteration: 1480075351, states[0] = 0.138529, states[40]= 0.004322
Saving checkpoint... 
Iteration: 1492035269, states[0] = 17.457641, states[40]= 0.005879
Saving checkpoint... 
Iteration: 1504065064, states[0] = -95.093262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516088681, states[0] = -95.169587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528058286, states[0] = -95.079700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539999836, states[0] = -37.309709, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1551570992, states[0] = -95.323989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563484861, states[0] = -95.201525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1575468954, states[0] = -95.165645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587423827, states[0] = -68.569880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1599327966, states[0] = 18.453351, states[40]= 0.007999
Saving checkpoint... 
Iteration: 1611291577, states[0] = -95.356474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622864113, states[0] = -95.157435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634836398, states[0] = -88.739786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1646702969, states[0] = 41.007972, states[40]= 0.089755
Saving checkpoint... 
Iteration: 1658166282, states[0] = -2.951018, states[40]= 0.004315
Saving checkpoint... 
Iteration: 1670120441, states[0] = 21.326556, states[40]= 0.011668
Saving checkpoint... 
Iteration: 1681582741, states[0] = -19.512296, states[40]= 0.001098
Saving checkpoint... 
Iteration: 1693495718, states[0] = -95.361973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705437235, states[0] = -95.306238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717357437, states[0] = -95.123744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729208371, states[0] = 26.338821, states[40]= 0.075336
Saving checkpoint... 
Iteration: 1741185722, states[0] = -95.354882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753140664, states[0] = -95.310667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765110751, states[0] = -95.266490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776609072, states[0] = 25.792001, states[40]= 0.065783
Saving checkpoint... 
Iteration: 1788573000, states[0] = -95.344507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800208565, states[0] = -94.966705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1812239915, states[0] = -94.956199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823824397, states[0] = -95.025724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835847226, states[0] = -95.025810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847433312, states[0] = -95.046116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859045159, states[0] = 13.568221, states[40]= 0.005292
Saving checkpoint... 
Iteration: 1871010382, states[0] = 24.229848, states[40]= 0.050373
Saving checkpoint... 
Iteration: 1882613174, states[0] = -33.268593, states[40]= 0.000318
Saving checkpoint... 
Iteration: 1894623810, states[0] = -44.011177, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1906587684, states[0] = -8.683481, states[40]= 0.002638
Saving checkpoint... 
Iteration: 1918200129, states[0] = -94.829087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930195827, states[0] = -94.818985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942134681, states[0] = -55.802960, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1953594932, states[0] = -15.156755, states[40]= 0.001457
Saving checkpoint... 
Iteration: 1965531586, states[0] = 18.694997, states[40]= 0.006304
Saving checkpoint... 
Iteration: 1977429431, states[0] = -95.022880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989000377, states[0] = -48.224163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001041860, states[0] = 15.051033, states[40]= 0.005424
Saving checkpoint... 
Iteration: 2012582381, states[0] = -4.377164, states[40]= 0.003556
Saving checkpoint... 
Iteration: 2024443394, states[0] = -95.025431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035963824, states[0] = -95.029100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047928794, states[0] = -95.022212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059897493, states[0] = -95.013808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071521724, states[0] = 21.544372, states[40]= 0.009336
Saving checkpoint... 
Iteration: 2083561884, states[0] = 6.881267, states[40]= 0.004914
Saving checkpoint... 
Iteration: 2095464264, states[0] = -95.029054, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909881
 - CaMKt in component CaMK (millimolar): 0.006714
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.622819
 - nass in component intracellular_ions (millimolar): 6.622879
 - ki in component intracellular_ions (millimolar): 145.359089
 - kss in component intracellular_ions (millimolar): 145.359069
 - cansr in component intracellular_ions (millimolar): 1.296911
 - cajsr in component intracellular_ions (millimolar): 1.259357
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880140
 - hs in component INa (dimensionless): 0.880135
 - j in component INa (dimensionless): 0.880106
 - hsp in component INa (dimensionless): 0.726093
 - jp in component INa (dimensionless): 0.880087
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710274
 - hLp in component INaL (dimensionless): 0.452574
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622354
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696923
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934170
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001552
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343225
 - xs1 in component IKs (dimensionless): 0.241593
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:09:40 (232845): called boinc_finish(0)

</stderr_txt>
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