𝕏

Task 54929460

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_280_0
Workunit 26082940
Created 27 Jun 2024, 4:00:51 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 11:34:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 27 min 48 sec
CPU time 1 hours 26 min 42 sec
Validate state Valid
Credit 59.16
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.66 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_280.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_280_0_r1858111500_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_280_0_r1858111500_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 122.746464
     * GNaL_b in INaL: 0.006992
     * Gto_b in Ito: 0.087894
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032618
     * GKs_b in IKs: 0.001808
     * GK1_b in IK1: 0.143722
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 62.354202
     * GKb_b in IKb: 0.003946
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038414
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12036754, states[0] = 16.084427, states[40]= 0.005471
Saving checkpoint... 
Iteration: 24080342, states[0] = -3.366739, states[40]= 0.003737
Saving checkpoint... 
Iteration: 36173644, states[0] = -94.361038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48294725, states[0] = -94.833017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59959361, states[0] = -94.905291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72097874, states[0] = -17.511222, states[40]= 0.001187
Saving checkpoint... 
Iteration: 83660960, states[0] = -87.403444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95744230, states[0] = -94.764345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107373847, states[0] = -94.875240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119320129, states[0] = -94.844848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131350911, states[0] = -94.863453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142884121, states[0] = -94.878204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154896018, states[0] = -94.882322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166893415, states[0] = -94.881274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178639875, states[0] = -59.044831, states[40]= 0.000006
Saving checkpoint... 
Iteration: 190580823, states[0] = -3.139775, states[40]= 0.003784
Saving checkpoint... 
Iteration: 202545639, states[0] = 13.291520, states[40]= 0.005084
Saving checkpoint... 
Iteration: 214469017, states[0] = -94.899942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226545744, states[0] = 13.253088, states[40]= 0.005082
Saving checkpoint... 
Iteration: 238570081, states[0] = 2.987689, states[40]= 0.004605
Saving checkpoint... 
Iteration: 250580900, states[0] = -3.186584, states[40]= 0.003775
Saving checkpoint... 
Iteration: 262623761, states[0] = -41.816372, states[40]= 0.000104
Saving checkpoint... 
Iteration: 274687020, states[0] = -94.639484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 286758197, states[0] = -94.781811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298821980, states[0] = -94.844745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310551089, states[0] = 11.215940, states[40]= 0.004988
Saving checkpoint... 
Iteration: 322220677, states[0] = -94.720675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334261944, states[0] = -94.786710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346393390, states[0] = -94.880811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358515098, states[0] = 21.965352, states[40]= 0.018525
Saving checkpoint... 
Iteration: 370523071, states[0] = 20.449135, states[40]= 0.007798
Saving checkpoint... 
Iteration: 382287637, states[0] = -94.815873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394493670, states[0] = -94.903484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406509727, states[0] = 23.137006, states[40]= 0.058432
Saving checkpoint... 
Iteration: 418626547, states[0] = -44.662192, states[40]= 0.000068
Saving checkpoint... 
Iteration: 430355688, states[0] = -94.864797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442457116, states[0] = -94.897545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454543004, states[0] = 14.267641, states[40]= 0.005155
Saving checkpoint... 
Iteration: 466677478, states[0] = -94.504403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478282949, states[0] = -94.811037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490360260, states[0] = -94.867013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502402859, states[0] = -94.883886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514384477, states[0] = -94.877426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526426980, states[0] = -94.890794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538431391, states[0] = -94.891890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550470312, states[0] = -94.899849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562568556, states[0] = 3.737598, states[40]= 0.004665
Saving checkpoint... 
Iteration: 574167630, states[0] = -92.886768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586124309, states[0] = -42.368845, states[40]= 0.000096
Saving checkpoint... 
Iteration: 598247160, states[0] = -94.765893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610342167, states[0] = -94.857383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622335590, states[0] = -94.853464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634383170, states[0] = -94.876842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646023653, states[0] = 20.313846, states[40]= 0.007558
Saving checkpoint... 
Iteration: 658118953, states[0] = -37.074071, states[40]= 0.000206
Saving checkpoint... 
Iteration: 670134651, states[0] = -53.296601, states[40]= 0.000017
Saving checkpoint... 
Iteration: 681852962, states[0] = -94.863233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693954704, states[0] = -94.896908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705650180, states[0] = -71.338618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 717739590, states[0] = -94.753991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729965450, states[0] = -94.898888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742043853, states[0] = 13.955917, states[40]= 0.005130
Saving checkpoint... 
Iteration: 754053162, states[0] = 10.402425, states[40]= 0.004962
Saving checkpoint... 
Iteration: 765719949, states[0] = -94.718958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777469168, states[0] = -94.899502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789411009, states[0] = -94.886212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801428999, states[0] = -94.891120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 813548581, states[0] = 12.182567, states[40]= 0.005026
Saving checkpoint... 
Iteration: 825594307, states[0] = -13.980788, states[40]= 0.001628
Saving checkpoint... 
Iteration: 837724553, states[0] = -94.727687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849822890, states[0] = -94.845002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861411790, states[0] = -94.886395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873066279, states[0] = 4.817245, states[40]= 0.004739
Saving checkpoint... 
Iteration: 884740346, states[0] = -94.755099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896870501, states[0] = -94.871447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908904327, states[0] = -94.884081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921072447, states[0] = 1.779390, states[40]= 0.004491
Saving checkpoint... 
Iteration: 932709764, states[0] = -94.698207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944767410, states[0] = -94.793166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956692641, states[0] = -94.658693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968677198, states[0] = -94.493628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980606632, states[0] = -25.451344, states[40]= 0.000707
Saving checkpoint... 
Iteration: 992362863, states[0] = -94.867916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004354754, states[0] = -94.863936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016373141, states[0] = -94.872507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028046073, states[0] = 13.130949, states[40]= 0.005074
Saving checkpoint... 
Iteration: 1040037379, states[0] = 16.263298, states[40]= 0.005403
Saving checkpoint... 
Iteration: 1051724502, states[0] = -94.727447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063800490, states[0] = -94.827378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075955026, states[0] = -94.896714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088051348, states[0] = 11.115286, states[40]= 0.004985
Saving checkpoint... 
Iteration: 1099675018, states[0] = -94.380681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111336077, states[0] = -94.853433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123361387, states[0] = -94.867128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135306049, states[0] = -94.832041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147312701, states[0] = -94.837335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158949367, states[0] = -94.895521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170885196, states[0] = -94.877258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182555275, states[0] = 9.557748, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1194648118, states[0] = -68.669772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206672705, states[0] = -94.164970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218734039, states[0] = -94.744404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230263543, states[0] = -94.788151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242420960, states[0] = -94.888730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254828120, states[0] = -94.848277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267322126, states[0] = -94.844187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279556774, states[0] = 8.948052, states[40]= 0.004918
Saving checkpoint... 
Iteration: 1291538598, states[0] = 15.842664, states[40]= 0.005335
Saving checkpoint... 
Iteration: 1303721192, states[0] = -94.720998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315779087, states[0] = -94.806366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327936841, states[0] = -94.892660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339999135, states[0] = -94.903562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352097300, states[0] = -16.748281, states[40]= 0.001265
Saving checkpoint... 
Iteration: 1364227886, states[0] = -94.733465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376339686, states[0] = -94.855421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388070951, states[0] = 2.551332, states[40]= 0.004566
Saving checkpoint... 
Iteration: 1400266606, states[0] = -94.791871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412285352, states[0] = -94.812880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424304632, states[0] = -94.830670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436565993, states[0] = 4.950010, states[40]= 0.004747
Saving checkpoint... 
Iteration: 1448600481, states[0] = -19.717002, states[40]= 0.001004
Saving checkpoint... 
Iteration: 1460283064, states[0] = -94.810493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471878994, states[0] = -94.874628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483959169, states[0] = -94.897234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496015181, states[0] = 21.952112, states[40]= 0.018258
Saving checkpoint... 
Iteration: 1508195181, states[0] = -29.415491, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1520179057, states[0] = -13.227159, states[40]= 0.001960
Saving checkpoint... 
Iteration: 1532122383, states[0] = 20.189155, states[40]= 0.009475
Saving checkpoint... 
Iteration: 1543800721, states[0] = 45.438948, states[40]= 0.006455
Saving checkpoint... 
Iteration: 1555761162, states[0] = -95.182396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567743556, states[0] = -95.166717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579721186, states[0] = -95.137086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591782875, states[0] = -95.214708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603838034, states[0] = 13.459087, states[40]= 0.006257
Saving checkpoint... 
Iteration: 1615442451, states[0] = -95.174338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1627094641, states[0] = -95.091498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638909583, states[0] = 24.041351, states[40]= 0.060386
Saving checkpoint... 
Iteration: 1650933171, states[0] = 15.650186, states[40]= 0.006694
Saving checkpoint... 
Iteration: 1663042223, states[0] = -92.489313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674761785, states[0] = -94.996597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686805677, states[0] = -95.116370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698975886, states[0] = -11.893472, states[40]= 0.002248
Saving checkpoint... 
Iteration: 1710652985, states[0] = 5.695232, states[40]= 0.005494
Saving checkpoint... 
Iteration: 1722777238, states[0] = -95.050358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734940803, states[0] = 12.085646, states[40]= 0.006075
Saving checkpoint... 
Iteration: 1746704847, states[0] = -43.375842, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1758778021, states[0] = -95.052484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770942757, states[0] = 11.120768, states[40]= 0.005965
Saving checkpoint... 
Iteration: 1782724559, states[0] = -67.809683, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1794993025, states[0] = -30.331590, states[40]= 0.000460
Saving checkpoint... 
Iteration: 1806832459, states[0] = -94.918003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818943078, states[0] = -94.945204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831133851, states[0] = -54.717654, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1843140811, states[0] = -61.807697, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1855195150, states[0] = -94.683618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867332212, states[0] = -94.863650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879104998, states[0] = -24.372510, states[40]= 0.000756
Saving checkpoint... 
Iteration: 1890728186, states[0] = -94.740473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902837307, states[0] = -94.858366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914947000, states[0] = -94.897831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1926933736, states[0] = -94.893861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938614010, states[0] = -32.445176, states[40]= 0.000373
Saving checkpoint... 
Iteration: 1950710043, states[0] = -94.699286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963032782, states[0] = 17.767563, states[40]= 0.005756
Saving checkpoint... 
Iteration: 1975275219, states[0] = -94.802195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987369156, states[0] = -94.870490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999104042, states[0] = -23.052682, states[40]= 0.000818
Saving checkpoint... 
Iteration: 2011246347, states[0] = -94.763869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023424124, states[0] = -94.889139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035434079, states[0] = -94.891580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047514988, states[0] = 21.983007, states[40]= 0.018887
Saving checkpoint... 
Iteration: 2059112203, states[0] = -30.661335, states[40]= 0.000455
Saving checkpoint... 
Iteration: 2071251626, states[0] = -94.771437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082997832, states[0] = -94.902861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095282342, states[0] = -94.809267, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.778991
 - CaMKt in component CaMK (millimolar): 0.007190
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.847360
 - nass in component intracellular_ions (millimolar): 6.847422
 - ki in component intracellular_ions (millimolar): 145.126643
 - kss in component intracellular_ions (millimolar): 145.126622
 - cansr in component intracellular_ions (millimolar): 1.327231
 - cajsr in component intracellular_ions (millimolar): 1.289101
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003664
 - hf in component INa (dimensionless): 0.877853
 - hs in component INa (dimensionless): 0.877847
 - j in component INa (dimensionless): 0.877815
 - hsp in component INa (dimensionless): 0.721792
 - jp in component INa (dimensionless): 0.877794
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706188
 - hLp in component INaL (dimensionless): 0.446866
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.619419
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.693727
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935250
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001661
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339899
 - xs1 in component IKs (dimensionless): 0.241844
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997369
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:33:41 (233382): called boinc_finish(0)

</stderr_txt>
]]>


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