𝕏

Task 54929458

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_779_0
Workunit 26082939
Created 27 Jun 2024, 4:00:51 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 10:27:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 29 min 9 sec
CPU time 1 hours 27 min 52 sec
Validate state Valid
Credit 56.99
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_779.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_779_0_r1449184721_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_779_0_r1449184721_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.557341
     * GNaL_b in INaL: 0.009020
     * Gto_b in Ito: 0.069058
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032558
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.156155
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 69.730090
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043640
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12242652, states[0] = -95.018279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24086042, states[0] = -4.707179, states[40]= 0.003499
Saving checkpoint... 
Iteration: 36094302, states[0] = -10.545923, states[40]= 0.002245
Saving checkpoint... 
Iteration: 48011503, states[0] = 25.390777, states[40]= 0.036230
Saving checkpoint... 
Iteration: 59828540, states[0] = -95.020867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71435772, states[0] = -95.054751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82997159, states[0] = -95.060720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94901006, states[0] = -95.039323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106401655, states[0] = -95.037590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118318495, states[0] = -94.998964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129808011, states[0] = -94.990769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141773456, states[0] = -94.960002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153282270, states[0] = -94.968205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164882350, states[0] = -95.027456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176770986, states[0] = -94.956309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188270051, states[0] = -94.955133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200308271, states[0] = -94.988814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212310055, states[0] = -94.989997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223879878, states[0] = -95.025836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235693076, states[0] = -94.832808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247274504, states[0] = -94.959390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259074263, states[0] = 3.751824, states[40]= 0.004687
Saving checkpoint... 
Iteration: 270991219, states[0] = -95.050431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282444410, states[0] = -95.043038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294285705, states[0] = -94.970110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306204533, states[0] = -94.857128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317962669, states[0] = -95.046274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329868931, states[0] = -95.021476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341671162, states[0] = -93.069103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353630667, states[0] = -42.100056, states[40]= 0.000106
Saving checkpoint... 
Iteration: 365561977, states[0] = 9.274244, states[40]= 0.004996
Saving checkpoint... 
Iteration: 377509391, states[0] = 26.293433, states[40]= 0.058138
Saving checkpoint... 
Iteration: 389448573, states[0] = -95.043746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401385686, states[0] = -95.027612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413246890, states[0] = -94.926651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425146102, states[0] = -59.357005, states[40]= 0.000007
Saving checkpoint... 
Iteration: 437158200, states[0] = -75.802990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449069529, states[0] = 5.987673, states[40]= 0.004844
Saving checkpoint... 
Iteration: 460655595, states[0] = -71.777304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472574325, states[0] = 3.722801, states[40]= 0.004685
Saving checkpoint... 
Iteration: 484513335, states[0] = 25.153136, states[40]= 0.025051
Saving checkpoint... 
Iteration: 496411217, states[0] = -95.035272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508356478, states[0] = -95.016081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519892244, states[0] = -95.029706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531889039, states[0] = -95.028658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543782128, states[0] = -94.966628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555631809, states[0] = -43.278096, states[40]= 0.000089
Saving checkpoint... 
Iteration: 567561824, states[0] = 9.338165, states[40]= 0.004999
Saving checkpoint... 
Iteration: 579137705, states[0] = -49.653100, states[40]= 0.000033
Saving checkpoint... 
Iteration: 591131917, states[0] = -43.390509, states[40]= 0.000087
Saving checkpoint... 
Iteration: 603096685, states[0] = -10.797112, states[40]= 0.002173
Saving checkpoint... 
Iteration: 615029520, states[0] = 21.275042, states[40]= 0.006420
Saving checkpoint... 
Iteration: 627023133, states[0] = 23.055167, states[40]= 0.008125
Saving checkpoint... 
Iteration: 638553444, states[0] = 12.714420, states[40]= 0.005103
Saving checkpoint... 
Iteration: 650590681, states[0] = -6.009074, states[40]= 0.003191
Saving checkpoint... 
Iteration: 662450268, states[0] = -95.043902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673966352, states[0] = -95.046651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685433511, states[0] = -95.040534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697277491, states[0] = -94.962053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709166380, states[0] = -88.989509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720779979, states[0] = -94.964472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732689777, states[0] = -94.821878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744413747, states[0] = -95.035796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756274180, states[0] = -94.958684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768232518, states[0] = -94.905604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780166202, states[0] = -88.760773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792033898, states[0] = 19.880501, states[40]= 0.005874
Saving checkpoint... 
Iteration: 803521148, states[0] = 23.535300, states[40]= 0.009200
Saving checkpoint... 
Iteration: 815513677, states[0] = 25.082445, states[40]= 0.023486
Saving checkpoint... 
Iteration: 827533449, states[0] = 20.028871, states[40]= 0.005918
Saving checkpoint... 
Iteration: 839475795, states[0] = -95.047987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850957863, states[0] = -95.045147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862535384, states[0] = 19.381887, states[40]= 0.005742
Saving checkpoint... 
Iteration: 874380539, states[0] = -95.025541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886124025, states[0] = -35.579848, states[40]= 0.000266
Saving checkpoint... 
Iteration: 898045052, states[0] = 15.921487, states[40]= 0.005254
Saving checkpoint... 
Iteration: 909601772, states[0] = -15.264655, states[40]= 0.001436
Saving checkpoint... 
Iteration: 921180380, states[0] = -94.697738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933053676, states[0] = 12.623654, states[40]= 0.005100
Saving checkpoint... 
Iteration: 944575450, states[0] = 3.165433, states[40]= 0.004637
Saving checkpoint... 
Iteration: 956553284, states[0] = 12.777024, states[40]= 0.005105
Saving checkpoint... 
Iteration: 968479019, states[0] = -95.048371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980376685, states[0] = -95.024076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991874336, states[0] = -95.023188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003839696, states[0] = -95.007583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015669374, states[0] = -91.985867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027136635, states[0] = -48.463102, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1039003073, states[0] = 38.379834, states[40]= 0.134240
Saving checkpoint... 
Iteration: 1050962122, states[0] = -95.045748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062876367, states[0] = -95.023910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074724320, states[0] = -94.892233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086165696, states[0] = -88.081417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098104915, states[0] = -18.102770, states[40]= 0.001137
Saving checkpoint... 
Iteration: 1109623466, states[0] = -35.051280, states[40]= 0.000285
Saving checkpoint... 
Iteration: 1121225892, states[0] = -94.894809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133113599, states[0] = -25.964706, states[40]= 0.000720
Saving checkpoint... 
Iteration: 1144673082, states[0] = -93.799287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156665416, states[0] = -87.688128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168209044, states[0] = -94.865152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180115296, states[0] = -27.506473, states[40]= 0.000645
Saving checkpoint... 
Iteration: 1192000730, states[0] = 41.405823, states[40]= 0.008928
Saving checkpoint... 
Iteration: 1203928074, states[0] = -95.039025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215521467, states[0] = 23.460672, states[40]= 0.008996
Saving checkpoint... 
Iteration: 1227504199, states[0] = 33.491220, states[40]= 0.145686
Saving checkpoint... 
Iteration: 1239047121, states[0] = 15.145337, states[40]= 0.005204
Saving checkpoint... 
Iteration: 1251140745, states[0] = -53.093941, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1263159209, states[0] = -77.453015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274766351, states[0] = -94.950030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286685695, states[0] = -94.797726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298311754, states[0] = -94.990347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310264279, states[0] = -94.947685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322260544, states[0] = -94.943362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333706330, states[0] = -94.859947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345606077, states[0] = -19.155452, states[40]= 0.001056
Saving checkpoint... 
Iteration: 1357514596, states[0] = 24.898574, states[40]= 0.019930
Saving checkpoint... 
Iteration: 1369386570, states[0] = -95.027348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381252638, states[0] = -94.933633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393171417, states[0] = -93.187209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404559157, states[0] = 10.436944, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1416404807, states[0] = -95.032972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428397420, states[0] = -95.030793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440315489, states[0] = -94.992829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451797671, states[0] = -94.979674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463718695, states[0] = -94.882410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475642345, states[0] = -54.936701, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1487592397, states[0] = -7.306206, states[40]= 0.002910
Saving checkpoint... 
Iteration: 1499532198, states[0] = 20.436285, states[40]= 0.006054
Saving checkpoint... 
Iteration: 1511500932, states[0] = -29.833022, states[40]= 0.000497
Saving checkpoint... 
Iteration: 1523388294, states[0] = -95.300215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535244134, states[0] = -89.375171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1547177525, states[0] = -7.932254, states[40]= 0.003141
Saving checkpoint... 
Iteration: 1558746901, states[0] = -95.286793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570246655, states[0] = 11.519795, states[40]= 0.005962
Saving checkpoint... 
Iteration: 1582147571, states[0] = -95.294085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594097482, states[0] = -95.219884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606063607, states[0] = -95.131837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617679418, states[0] = -10.343373, states[40]= 0.002578
Saving checkpoint... 
Iteration: 1629587784, states[0] = -95.335522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641531144, states[0] = -95.278542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653368883, states[0] = -1.480959, states[40]= 0.004609
Saving checkpoint... 
Iteration: 1665309359, states[0] = 26.803335, states[40]= 0.058182
Saving checkpoint... 
Iteration: 1677204324, states[0] = -95.236517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688714239, states[0] = 24.859801, states[40]= 0.022741
Saving checkpoint... 
Iteration: 1700631450, states[0] = -95.279634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712038731, states[0] = -95.289163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723829838, states[0] = 19.240192, states[40]= 0.007400
Saving checkpoint... 
Iteration: 1735662209, states[0] = -95.125441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1747188304, states[0] = -95.337022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759111009, states[0] = -95.248516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770912021, states[0] = 25.608357, states[40]= 0.033871
Saving checkpoint... 
Iteration: 1782440375, states[0] = -86.007705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794272643, states[0] = -95.324589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1806143667, states[0] = -61.516200, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1817982473, states[0] = -95.091893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829827383, states[0] = -95.031362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1841744773, states[0] = -94.945166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853598051, states[0] = -12.739163, states[40]= 0.001824
Saving checkpoint... 
Iteration: 1865021630, states[0] = 23.315881, states[40]= 0.008861
Saving checkpoint... 
Iteration: 1876472844, states[0] = -95.054856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887943224, states[0] = -95.047469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899414425, states[0] = -95.039302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911249416, states[0] = -94.931990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923193932, states[0] = -94.835928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934744644, states[0] = -94.924096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1946644309, states[0] = -57.310404, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1958518848, states[0] = 24.040409, states[40]= 0.011207
Saving checkpoint... 
Iteration: 1970338012, states[0] = -95.006575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981798274, states[0] = -94.980161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993759143, states[0] = -94.941512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005736012, states[0] = -94.910340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017821017, states[0] = -94.996189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029581277, states[0] = 0.066969, states[40]= 0.004290
Saving checkpoint... 
Iteration: 2041095175, states[0] = -9.533438, states[40]= 0.002430
Saving checkpoint... 
Iteration: 2052916589, states[0] = -95.035757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064574918, states[0] = 3.429892, states[40]= 0.004660
Saving checkpoint... 
Iteration: 2076534121, states[0] = 19.806327, states[40]= 0.005853
Saving checkpoint... 
Iteration: 2088036843, states[0] = 18.881853, states[40]= 0.005632
Saving checkpoint... 
Iteration: 2099872263, states[0] = -95.021705, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.926212
 - CaMKt in component CaMK (millimolar): 0.006993
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.579377
 - nass in component intracellular_ions (millimolar): 6.579437
 - ki in component intracellular_ions (millimolar): 145.399146
 - kss in component intracellular_ions (millimolar): 145.399126
 - cansr in component intracellular_ions (millimolar): 1.310420
 - cajsr in component intracellular_ions (millimolar): 1.271768
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880423
 - hs in component INa (dimensionless): 0.880418
 - j in component INa (dimensionless): 0.880390
 - hsp in component INa (dimensionless): 0.726626
 - jp in component INa (dimensionless): 0.880370
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709002
 - hLp in component INaL (dimensionless): 0.448132
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.614081
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.686854
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.925347
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999853
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.350346
 - xs1 in component IKs (dimensionless): 0.257708
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:30:58 (233282): called boinc_finish(0)

</stderr_txt>
]]>


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