𝕏

Task 54929418

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_557_0
Workunit 26082919
Created 27 Jun 2024, 4:00:51 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 3:21:40 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 57 sec
CPU time 1 hours 27 min 29 sec
Validate state Valid
Credit 61.25
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_557.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_557_0_r916826258_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_557_0_r916826258_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.892293
     * GNaL_b in INaL: 0.006984
     * Gto_b in Ito: 0.068429
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.168332
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 62.354458
     * GKb_b in IKb: 0.003867
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033592
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12001391, states[0] = 49.921801, states[40]= 0.047567
Saving checkpoint... 
Iteration: 23628562, states[0] = -54.733329, states[40]= 0.000013
Saving checkpoint... 
Iteration: 35768837, states[0] = -94.951652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47795516, states[0] = -94.970273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59451200, states[0] = -95.027255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71024297, states[0] = 21.104287, states[40]= 0.008138
Saving checkpoint... 
Iteration: 83065408, states[0] = 4.087002, states[40]= 0.004903
Saving checkpoint... 
Iteration: 95087445, states[0] = -11.085466, states[40]= 0.002211
Saving checkpoint... 
Iteration: 107181573, states[0] = -94.808055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118772846, states[0] = -94.944186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130697630, states[0] = -94.839746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142749958, states[0] = -94.919660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154319553, states[0] = -94.978129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166315141, states[0] = -94.975380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178228479, states[0] = -94.891094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190324951, states[0] = -94.980921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201945456, states[0] = -95.020489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213519166, states[0] = 22.655982, states[40]= 0.011552
Saving checkpoint... 
Iteration: 225529462, states[0] = 19.448806, states[40]= 0.006817
Saving checkpoint... 
Iteration: 237510483, states[0] = 25.305152, states[40]= 0.047745
Saving checkpoint... 
Iteration: 249514724, states[0] = 23.867006, states[40]= 0.020675
Saving checkpoint... 
Iteration: 261522199, states[0] = 21.790171, states[40]= 0.009119
Saving checkpoint... 
Iteration: 273089014, states[0] = -12.433725, states[40]= 0.001949
Saving checkpoint... 
Iteration: 285066669, states[0] = 3.514750, states[40]= 0.004850
Saving checkpoint... 
Iteration: 297059555, states[0] = 7.022794, states[40]= 0.005099
Saving checkpoint... 
Iteration: 309045450, states[0] = 13.234578, states[40]= 0.005466
Saving checkpoint... 
Iteration: 321068020, states[0] = 2.800749, states[40]= 0.004783
Saving checkpoint... 
Iteration: 333120641, states[0] = -44.222869, states[40]= 0.000071
Saving checkpoint... 
Iteration: 345166267, states[0] = -94.679843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357235337, states[0] = -94.900461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369243533, states[0] = -94.911175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380859848, states[0] = -94.997047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392934618, states[0] = -95.018257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404929013, states[0] = -95.017122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416600647, states[0] = -23.830533, states[40]= 0.000768
Saving checkpoint... 
Iteration: 428264821, states[0] = -94.935149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440266045, states[0] = -94.936370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451826946, states[0] = -94.981722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463740954, states[0] = -94.907842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475737757, states[0] = -94.903650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487765845, states[0] = -94.936143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499323250, states[0] = -94.979654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510952173, states[0] = -95.021365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522522733, states[0] = 21.631455, states[40]= 0.008833
Saving checkpoint... 
Iteration: 534483553, states[0] = -95.025872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546078956, states[0] = -3.947349, states[40]= 0.003763
Saving checkpoint... 
Iteration: 558135867, states[0] = -62.253604, states[40]= 0.000004
Saving checkpoint... 
Iteration: 570025743, states[0] = 20.696075, states[40]= 0.007664
Saving checkpoint... 
Iteration: 581907806, states[0] = -95.012176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593785858, states[0] = -94.954169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605423967, states[0] = -95.015940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617426556, states[0] = -95.016487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628989172, states[0] = -95.026494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640605207, states[0] = -28.340708, states[40]= 0.000548
Saving checkpoint... 
Iteration: 652645504, states[0] = -76.481206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664153793, states[0] = -90.257866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676135931, states[0] = -62.335857, states[40]= 0.000004
Saving checkpoint... 
Iteration: 688036533, states[0] = 16.841102, states[40]= 0.005961
Saving checkpoint... 
Iteration: 699988981, states[0] = -95.026432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712011843, states[0] = 24.758593, states[40]= 0.035674
Saving checkpoint... 
Iteration: 723418337, states[0] = -95.014621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735013688, states[0] = 24.164309, states[40]= 0.024811
Saving checkpoint... 
Iteration: 746984880, states[0] = -95.025914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758699233, states[0] = -94.841640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770625831, states[0] = -50.098101, states[40]= 0.000029
Saving checkpoint... 
Iteration: 782626138, states[0] = -50.454582, states[40]= 0.000027
Saving checkpoint... 
Iteration: 794528418, states[0] = 19.809253, states[40]= 0.007013
Saving checkpoint... 
Iteration: 806548839, states[0] = 11.801805, states[40]= 0.005359
Saving checkpoint... 
Iteration: 818464210, states[0] = -95.023084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830445330, states[0] = -95.020007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842529963, states[0] = 19.274459, states[40]= 0.006732
Saving checkpoint... 
Iteration: 854483402, states[0] = -95.025671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866441974, states[0] = -95.019381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878431959, states[0] = -95.017453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889951783, states[0] = -95.021084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901414987, states[0] = -95.013743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912971993, states[0] = -95.024145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924942480, states[0] = -95.019440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936893483, states[0] = -95.008116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948449356, states[0] = -95.020641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960492279, states[0] = -95.026665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972497931, states[0] = -95.027283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983723263, states[0] = -94.882624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994918037, states[0] = -95.014398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006489008, states[0] = -95.026260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018359346, states[0] = -94.996485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029841902, states[0] = -94.988942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041770819, states[0] = -94.940671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053329852, states[0] = -94.982933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065258978, states[0] = -94.928706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077178352, states[0] = -94.798226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089130232, states[0] = -55.287981, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1100704492, states[0] = -94.851154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112695210, states[0] = -94.833765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124322973, states[0] = -94.979142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136328820, states[0] = -94.982339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148299862, states[0] = -94.964499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160269931, states[0] = -94.939757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171860786, states[0] = -94.996965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183896644, states[0] = -95.008872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196007360, states[0] = 27.516149, states[40]= 0.094435
Saving checkpoint... 
Iteration: 1208039252, states[0] = 15.771964, states[40]= 0.005764
Saving checkpoint... 
Iteration: 1219598476, states[0] = -21.685824, states[40]= 0.000883
Saving checkpoint... 
Iteration: 1231683532, states[0] = -94.810184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243257848, states[0] = -94.927387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255262472, states[0] = -94.932276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266820450, states[0] = -94.977621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278814700, states[0] = -94.974196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290716217, states[0] = -94.871272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302258125, states[0] = -94.927653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314157572, states[0] = -93.211224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326064328, states[0] = 4.711922, states[40]= 0.004948
Saving checkpoint... 
Iteration: 1338062065, states[0] = 5.826726, states[40]= 0.005027
Saving checkpoint... 
Iteration: 1350015178, states[0] = 23.741490, states[40]= 0.019192
Saving checkpoint... 
Iteration: 1361547960, states[0] = 12.176536, states[40]= 0.005384
Saving checkpoint... 
Iteration: 1373007318, states[0] = 27.562913, states[40]= 0.095249
Saving checkpoint... 
Iteration: 1384575556, states[0] = -1.618622, states[40]= 0.004198
Saving checkpoint... 
Iteration: 1396476118, states[0] = -95.024428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408059831, states[0] = 6.893457, states[40]= 0.005092
Saving checkpoint... 
Iteration: 1419697983, states[0] = -94.838899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431769726, states[0] = -94.939405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443378538, states[0] = -95.003210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455357855, states[0] = -94.995640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467407667, states[0] = -95.011637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479746599, states[0] = -94.914327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491824450, states[0] = -94.979759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503783005, states[0] = -95.112393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515746426, states[0] = -94.895416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1527672945, states[0] = -9.431208, states[40]= 0.002846
Saving checkpoint... 
Iteration: 1539196486, states[0] = -95.165622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551182727, states[0] = -95.145350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562755840, states[0] = 3.635988, states[40]= 0.005477
Saving checkpoint... 
Iteration: 1574738996, states[0] = 13.162613, states[40]= 0.006589
Saving checkpoint... 
Iteration: 1586369422, states[0] = -95.271373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598322619, states[0] = -95.223662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1610246631, states[0] = -95.014175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622297986, states[0] = -95.187324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634306157, states[0] = -95.201593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645918188, states[0] = -65.410170, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1657910758, states[0] = -55.093371, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1669905479, states[0] = -48.233080, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1681680591, states[0] = -95.154921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693729275, states[0] = -95.235356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705346241, states[0] = -95.010205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716966011, states[0] = -4.113028, states[40]= 0.004167
Saving checkpoint... 
Iteration: 1728621020, states[0] = 21.404395, states[40]= 0.011187
Saving checkpoint... 
Iteration: 1740235097, states[0] = -95.242489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752279791, states[0] = -95.283901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764347666, states[0] = 8.332376, states[40]= 0.005986
Saving checkpoint... 
Iteration: 1776285595, states[0] = -95.287960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788243410, states[0] = -95.251783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800147974, states[0] = -94.501862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1811668181, states[0] = -94.799453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823178989, states[0] = -94.831352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835149553, states[0] = -86.995629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846772997, states[0] = -94.959387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858674858, states[0] = -94.800139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1870233738, states[0] = -94.906234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881964276, states[0] = -95.028685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893502731, states[0] = 41.709226, states[40]= 0.117618
Saving checkpoint... 
Iteration: 1905029784, states[0] = 19.293778, states[40]= 0.006759
Saving checkpoint... 
Iteration: 1916916283, states[0] = -95.015735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928831878, states[0] = -94.985100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940370371, states[0] = -95.001261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952206566, states[0] = -94.855211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963749749, states[0] = -94.918396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975330872, states[0] = -94.983338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986939465, states[0] = -95.018549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998576582, states[0] = -2.303362, states[40]= 0.004079
Saving checkpoint... 
Iteration: 2010621323, states[0] = -44.988588, states[40]= 0.000063
Saving checkpoint... 
Iteration: 2022567392, states[0] = 3.132291, states[40]= 0.004815
Saving checkpoint... 
Iteration: 2034074712, states[0] = -1.080878, states[40]= 0.004286
Saving checkpoint... 
Iteration: 2045549922, states[0] = 11.336277, states[40]= 0.005330
Saving checkpoint... 
Iteration: 2057479001, states[0] = -95.024424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069406147, states[0] = -95.010890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081373081, states[0] = -95.000965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093000117, states[0] = -80.650511, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.902701
 - CaMKt in component CaMK (millimolar): 0.006841
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.843319
 - nass in component intracellular_ions (millimolar): 6.843379
 - ki in component intracellular_ions (millimolar): 145.134185
 - kss in component intracellular_ions (millimolar): 145.134165
 - cansr in component intracellular_ions (millimolar): 1.315753
 - cajsr in component intracellular_ions (millimolar): 1.278589
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880016
 - hs in component INa (dimensionless): 0.880011
 - j in component INa (dimensionless): 0.879985
 - hsp in component INa (dimensionless): 0.725860
 - jp in component INa (dimensionless): 0.879967
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711566
 - hLp in component INaL (dimensionless): 0.457019
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.627293
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.702869
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935821
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001637
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337863
 - xs1 in component IKs (dimensionless): 0.235117
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:41:16 (232641): called boinc_finish(0)

</stderr_txt>
]]>


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