𝕏

Task 54929412

Name HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_855_0
Workunit 26082916
Created 27 Jun 2024, 4:00:46 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 30 Jun 2024, 14:05:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 54 sec
CPU time 1 hours 27 min 22 sec
Validate state Valid
Credit 60.00
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_855.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_855_0_r540072643_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060045089179_ORdGradInc_k_24-Pueyo_APDR-conf_855_0_r540072643_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 123.320680
     * GNaL_b in INaL: 0.006581
     * Gto_b in Ito: 0.077118
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032562
     * GKs_b in IKs: 0.001903
     * GK1_b in IK1: 0.150461
     * Gncx_b in INaCa_i: 0.000963
     * Pnak_b in INaK: 68.133195
     * GKb_b in IKb: 0.003984
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033722
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11908593, states[0] = -94.968656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23554657, states[0] = 8.394268, states[40]= 0.005091
Saving checkpoint... 
Iteration: 35195633, states[0] = -94.725012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46827473, states[0] = -94.880670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58796745, states[0] = -94.851412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70362121, states[0] = -94.886695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82369595, states[0] = -94.886384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94331226, states[0] = -94.864982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105791169, states[0] = -94.834193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117660501, states[0] = -91.437170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129621288, states[0] = -42.768201, states[40]= 0.000086
Saving checkpoint... 
Iteration: 141226132, states[0] = -94.750082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153100408, states[0] = -22.309308, states[40]= 0.000843
Saving checkpoint... 
Iteration: 165069579, states[0] = 2.178669, states[40]= 0.004632
Saving checkpoint... 
Iteration: 177035860, states[0] = 16.675065, states[40]= 0.005886
Saving checkpoint... 
Iteration: 189032089, states[0] = 18.017662, states[40]= 0.006288
Saving checkpoint... 
Iteration: 200984860, states[0] = -94.907119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212555262, states[0] = 8.921722, states[40]= 0.005093
Saving checkpoint... 
Iteration: 224085087, states[0] = -8.043634, states[40]= 0.002815
Saving checkpoint... 
Iteration: 235768000, states[0] = -94.807004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247831122, states[0] = -94.859168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259919380, states[0] = -94.894433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271863417, states[0] = -94.875576, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283519779, states[0] = 21.700615, states[40]= 0.010890
Saving checkpoint... 
Iteration: 295202947, states[0] = -94.704970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307242789, states[0] = -94.774699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318884023, states[0] = -94.883646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330958750, states[0] = -94.902742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342952764, states[0] = -94.901652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354942495, states[0] = -94.899637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366589796, states[0] = -12.167841, states[40]= 0.001963
Saving checkpoint... 
Iteration: 378161491, states[0] = -92.004985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390105907, states[0] = -27.526473, states[40]= 0.000587
Saving checkpoint... 
Iteration: 402096029, states[0] = -18.055556, states[40]= 0.001143
Saving checkpoint... 
Iteration: 414054429, states[0] = 9.281436, states[40]= 0.005111
Saving checkpoint... 
Iteration: 425725261, states[0] = -94.746956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437301813, states[0] = -94.838813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448893262, states[0] = -94.886719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460871289, states[0] = -94.878728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472889300, states[0] = -94.885386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484882198, states[0] = -94.882887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496494368, states[0] = -94.907939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508316964, states[0] = -94.849936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520256967, states[0] = -94.793675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531947437, states[0] = -94.900524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543552711, states[0] = 10.009244, states[40]= 0.005147
Saving checkpoint... 
Iteration: 555541615, states[0] = 14.502924, states[40]= 0.005501
Saving checkpoint... 
Iteration: 567619287, states[0] = -40.597987, states[40]= 0.000119
Saving checkpoint... 
Iteration: 579272436, states[0] = -94.811570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591240749, states[0] = -94.771543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603295569, states[0] = -94.833601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614913412, states[0] = -94.892619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626952142, states[0] = -94.901370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638569486, states[0] = 2.244529, states[40]= 0.004638
Saving checkpoint... 
Iteration: 650165175, states[0] = -93.641787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661803327, states[0] = -94.839878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673616803, states[0] = -38.104683, states[40]= 0.000170
Saving checkpoint... 
Iteration: 685254807, states[0] = -94.790844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697265920, states[0] = -94.804295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708419148, states[0] = -94.894073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720252164, states[0] = -94.787392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731850576, states[0] = -94.869348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743769376, states[0] = -94.808151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755733955, states[0] = -94.761075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767689517, states[0] = -94.675503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779585266, states[0] = -8.187000, states[40]= 0.002783
Saving checkpoint... 
Iteration: 791170763, states[0] = -94.433622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802732707, states[0] = -94.759067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 814230143, states[0] = -94.754913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826213707, states[0] = -94.725877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837855868, states[0] = -94.871822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849606866, states[0] = -28.446538, states[40]= 0.000542
Saving checkpoint... 
Iteration: 861643200, states[0] = -67.174052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873618609, states[0] = -39.912194, states[40]= 0.000131
Saving checkpoint... 
Iteration: 885504561, states[0] = 32.076816, states[40]= 0.142900
Saving checkpoint... 
Iteration: 897471765, states[0] = -94.904565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909084236, states[0] = -7.340846, states[40]= 0.002971
Saving checkpoint... 
Iteration: 920829151, states[0] = -94.857539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932856232, states[0] = -94.871938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944833551, states[0] = -94.860132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956846318, states[0] = -94.867084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968910222, states[0] = -94.891543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980977553, states[0] = -94.905390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992957387, states[0] = -94.902120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004804982, states[0] = -94.840966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016735402, states[0] = -94.763194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028720326, states[0] = -94.737961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040763928, states[0] = -94.801797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052802170, states[0] = -94.838745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064800357, states[0] = -94.837291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076870088, states[0] = -94.877891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088573288, states[0] = 0.151374, states[40]= 0.004389
Saving checkpoint... 
Iteration: 1100505582, states[0] = 29.179481, states[40]= 0.132269
Saving checkpoint... 
Iteration: 1112493358, states[0] = -94.907463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124039877, states[0] = 15.175041, states[40]= 0.005595
Saving checkpoint... 
Iteration: 1135546611, states[0] = 12.520462, states[40]= 0.005302
Saving checkpoint... 
Iteration: 1147206767, states[0] = -94.712190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159102030, states[0] = -23.810950, states[40]= 0.000766
Saving checkpoint... 
Iteration: 1170844401, states[0] = -94.865972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182430270, states[0] = -94.896505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194030936, states[0] = 18.414667, states[40]= 0.006448
Saving checkpoint... 
Iteration: 1206077026, states[0] = -2.122880, states[40]= 0.004036
Saving checkpoint... 
Iteration: 1217677211, states[0] = -94.618057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229356143, states[0] = -94.871728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241415591, states[0] = -94.892845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253355616, states[0] = -94.871468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265306691, states[0] = -94.842121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277331801, states[0] = -94.858919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289077165, states[0] = -2.212405, states[40]= 0.004021
Saving checkpoint... 
Iteration: 1301074383, states[0] = -0.489754, states[40]= 0.004298
Saving checkpoint... 
Iteration: 1312661086, states[0] = -91.724896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324599675, states[0] = -21.553902, states[40]= 0.000885
Saving checkpoint... 
Iteration: 1336523925, states[0] = 20.596332, states[40]= 0.008185
Saving checkpoint... 
Iteration: 1348193253, states[0] = -94.683772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359781149, states[0] = -94.820042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371411284, states[0] = -94.891608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383417395, states[0] = -94.893237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395367854, states[0] = -94.876791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407327143, states[0] = -94.856034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419277440, states[0] = -94.816309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431259737, states[0] = -94.796577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443217357, states[0] = -94.732335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455086597, states[0] = -9.315291, states[40]= 0.002538
Saving checkpoint... 
Iteration: 1466720292, states[0] = -94.737649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478360185, states[0] = -94.873432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490369009, states[0] = -94.877214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502416707, states[0] = 22.892951, states[40]= 0.017919
Saving checkpoint... 
Iteration: 1514426821, states[0] = 19.006071, states[40]= 0.008439
Saving checkpoint... 
Iteration: 1526005411, states[0] = -95.074794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537594217, states[0] = -32.340656, states[40]= 0.000357
Saving checkpoint... 
Iteration: 1549541275, states[0] = 11.876700, states[40]= 0.006282
Saving checkpoint... 
Iteration: 1561504267, states[0] = 34.519939, states[40]= 0.117129
Saving checkpoint... 
Iteration: 1573093954, states[0] = -95.080704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585042247, states[0] = -93.768383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596948299, states[0] = 7.932252, states[40]= 0.005837
Saving checkpoint... 
Iteration: 1608571854, states[0] = -95.195806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620320862, states[0] = 20.887160, states[40]= 0.011315
Saving checkpoint... 
Iteration: 1632326164, states[0] = 18.781198, states[40]= 0.008548
Saving checkpoint... 
Iteration: 1644221983, states[0] = -95.138618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656206553, states[0] = -95.113037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667812462, states[0] = -54.978450, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1679425830, states[0] = 18.911106, states[40]= 0.008655
Saving checkpoint... 
Iteration: 1691419726, states[0] = 21.294758, states[40]= 0.012393
Saving checkpoint... 
Iteration: 1703356870, states[0] = -95.183775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715389811, states[0] = -95.212818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727367521, states[0] = -95.194348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1739364407, states[0] = -95.191405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751231806, states[0] = -83.061466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762807077, states[0] = 27.770921, states[40]= 0.095998
Saving checkpoint... 
Iteration: 1774327712, states[0] = -76.072590, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785888127, states[0] = -95.211592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797741417, states[0] = -93.581652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1809708992, states[0] = -94.769841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821637040, states[0] = -62.935281, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1833632165, states[0] = -56.404868, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1845668217, states[0] = -94.372069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857683795, states[0] = -94.674623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869714870, states[0] = -94.738069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881703737, states[0] = -94.713069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893728563, states[0] = -94.756892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905778696, states[0] = -94.820898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917403829, states[0] = -94.891686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929345434, states[0] = -94.867842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941276614, states[0] = -94.816411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953222326, states[0] = -94.741856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965170705, states[0] = -94.432441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976725400, states[0] = -94.746722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988370801, states[0] = -94.877938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000383029, states[0] = -94.882505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012348438, states[0] = -94.867671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024367483, states[0] = -94.876344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035924742, states[0] = -94.894746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047488780, states[0] = -94.906354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059466311, states[0] = -94.903030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070984158, states[0] = -94.905691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082595316, states[0] = -17.372227, states[40]= 0.001211
Saving checkpoint... 
Iteration: 2094504115, states[0] = 33.805211, states[40]= 0.141975
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.783551
 - CaMKt in component CaMK (millimolar): 0.006827
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.677406
 - nass in component intracellular_ions (millimolar): 6.677466
 - ki in component intracellular_ions (millimolar): 145.301520
 - kss in component intracellular_ions (millimolar): 145.301500
 - cansr in component intracellular_ions (millimolar): 1.309434
 - cajsr in component intracellular_ions (millimolar): 1.272014
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003662
 - hf in component INa (dimensionless): 0.877933
 - hs in component INa (dimensionless): 0.877928
 - j in component INa (dimensionless): 0.877898
 - hsp in component INa (dimensionless): 0.721945
 - jp in component INa (dimensionless): 0.877878
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707319
 - hLp in component INaL (dimensionless): 0.450026
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.623282
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.698143
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936359
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342704
 - xs1 in component IKs (dimensionless): 0.236655
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997368
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:04:51 (237432): called boinc_finish(0)

</stderr_txt>
]]>


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