𝕏

Task 54929327

Name HuVeMOp_20240627060042195046_ORdGradInc_k_24-Pueyo_APDR-conf_557_1
Workunit 26082873
Created 27 Jun 2024, 4:00:46 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 30 Jun 2024, 14:05:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 58 sec
CPU time 1 hours 27 min 26 sec
Validate state Valid
Credit 62.39
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060042195046_ORdGradInc_k_24-Pueyo_APDR-conf_557.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060042195046_ORdGradInc_k_24-Pueyo_APDR-conf_557_1_r620422816_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627060042195046_ORdGradInc_k_24-Pueyo_APDR-conf_557_1_r620422816_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.892293
     * GNaL_b in INaL: 0.006984
     * Gto_b in Ito: 0.068429
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033969
     * GKs_b in IKs: 0.001932
     * GK1_b in IK1: 0.168332
     * Gncx_b in INaCa_i: 0.000962
     * Pnak_b in INaK: 62.354458
     * GKb_b in IKb: 0.003867
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033592
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11889490, states[0] = -95.037828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23939408, states[0] = -95.037351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35982836, states[0] = -95.037871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48028742, states[0] = 19.592153, states[40]= 0.006942
Saving checkpoint... 
Iteration: 59404736, states[0] = -95.017497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70922839, states[0] = -95.020162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82918408, states[0] = -95.017958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94970647, states[0] = -95.026523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106568721, states[0] = 2.378376, states[40]= 0.004742
Saving checkpoint... 
Iteration: 118202309, states[0] = -94.848843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130143283, states[0] = -72.875165, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141679537, states[0] = -94.802349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153592894, states[0] = -16.205153, states[40]= 0.001364
Saving checkpoint... 
Iteration: 165427425, states[0] = -95.017214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176967393, states[0] = -95.024122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188945308, states[0] = -95.020515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200545630, states[0] = 13.157381, states[40]= 0.005459
Saving checkpoint... 
Iteration: 212551696, states[0] = 10.567019, states[40]= 0.005286
Saving checkpoint... 
Iteration: 224163075, states[0] = -94.498699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236188678, states[0] = -94.821424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248089671, states[0] = -13.058660, states[40]= 0.001837
Saving checkpoint... 
Iteration: 259836517, states[0] = -94.986807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271832384, states[0] = -94.984711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283502877, states[0] = 40.811587, states[40]= 0.121808
Saving checkpoint... 
Iteration: 295550582, states[0] = 11.052177, states[40]= 0.005313
Saving checkpoint... 
Iteration: 307204727, states[0] = -94.852039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318868318, states[0] = -95.000302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330459156, states[0] = -95.022595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342519393, states[0] = 22.593843, states[40]= 0.011306
Saving checkpoint... 
Iteration: 354524130, states[0] = 21.205629, states[40]= 0.008211
Saving checkpoint... 
Iteration: 366549894, states[0] = 11.349180, states[40]= 0.005331
Saving checkpoint... 
Iteration: 378135961, states[0] = -62.374863, states[40]= 0.000004
Saving checkpoint... 
Iteration: 390041823, states[0] = 14.734321, states[40]= 0.005619
Saving checkpoint... 
Iteration: 401214037, states[0] = -94.868175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412931763, states[0] = -95.017678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424876903, states[0] = -95.003245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436846434, states[0] = -94.991360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448748330, states[0] = -94.917003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460309683, states[0] = -94.971518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472289369, states[0] = -94.957050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483843647, states[0] = -94.990065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495842899, states[0] = -94.989712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507817359, states[0] = -94.976240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519816201, states[0] = -94.975540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531343096, states[0] = -94.989783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543369181, states[0] = -95.000484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555016137, states[0] = 23.479896, states[40]= 0.016587
Saving checkpoint... 
Iteration: 566660560, states[0] = -94.155356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578246320, states[0] = -94.914503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590241340, states[0] = -94.908266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602216359, states[0] = -94.871899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614166898, states[0] = -94.698830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626123773, states[0] = -47.732231, states[40]= 0.000041
Saving checkpoint... 
Iteration: 638114660, states[0] = -37.853413, states[40]= 0.000179
Saving checkpoint... 
Iteration: 649759546, states[0] = -94.929551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661784372, states[0] = -94.952909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673878166, states[0] = -95.003525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685443441, states[0] = -95.019751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696992713, states[0] = -95.026864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708435186, states[0] = -95.018188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720045914, states[0] = 13.040344, states[40]= 0.005449
Saving checkpoint... 
Iteration: 731617947, states[0] = -41.301681, states[40]= 0.000109
Saving checkpoint... 
Iteration: 743189802, states[0] = -94.823349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755117907, states[0] = -41.258983, states[40]= 0.000110
Saving checkpoint... 
Iteration: 767066299, states[0] = 3.707556, states[40]= 0.004867
Saving checkpoint... 
Iteration: 779062995, states[0] = 5.372986, states[40]= 0.004996
Saving checkpoint... 
Iteration: 791017761, states[0] = 23.041171, states[40]= 0.013419
Saving checkpoint... 
Iteration: 803032275, states[0] = 18.445704, states[40]= 0.006398
Saving checkpoint... 
Iteration: 815028449, states[0] = 19.798683, states[40]= 0.007006
Saving checkpoint... 
Iteration: 827083746, states[0] = -7.697310, states[40]= 0.002944
Saving checkpoint... 
Iteration: 839166468, states[0] = -94.686037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851246603, states[0] = -94.914691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863256753, states[0] = -94.926410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874885224, states[0] = -95.005680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886577463, states[0] = -2.893289, states[40]= 0.003970
Saving checkpoint... 
Iteration: 898558356, states[0] = 7.581877, states[40]= 0.005130
Saving checkpoint... 
Iteration: 910183073, states[0] = -94.809383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921823921, states[0] = -94.979789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933423286, states[0] = -95.015605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945421975, states[0] = -95.015311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957058681, states[0] = 7.431168, states[40]= 0.005122
Saving checkpoint... 
Iteration: 969074783, states[0] = -1.123162, states[40]= 0.004279
Saving checkpoint... 
Iteration: 981053231, states[0] = 9.895461, states[40]= 0.005250
Saving checkpoint... 
Iteration: 993000741, states[0] = 44.411103, states[40]= 0.009406
Saving checkpoint... 
Iteration: 1004956646, states[0] = -95.021812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016894910, states[0] = -95.008478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028539973, states[0] = 15.483409, states[40]= 0.005720
Saving checkpoint... 
Iteration: 1040086651, states[0] = -10.241473, states[40]= 0.002384
Saving checkpoint... 
Iteration: 1052027950, states[0] = 19.968109, states[40]= 0.007109
Saving checkpoint... 
Iteration: 1063626427, states[0] = -50.790755, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1075264521, states[0] = -94.934476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086835846, states[0] = -94.985984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098868494, states[0] = -94.999918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110438707, states[0] = -95.018635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122412640, states[0] = -95.013059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134418034, states[0] = -95.014318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145990566, states[0] = -95.026363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158040537, states[0] = 15.256386, states[40]= 0.005687
Saving checkpoint... 
Iteration: 1170031327, states[0] = 18.789532, states[40]= 0.006524
Saving checkpoint... 
Iteration: 1182163763, states[0] = -94.553226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193770534, states[0] = -94.940313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205797741, states[0] = -94.962949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217700109, states[0] = -94.843020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229321116, states[0] = -94.978026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240937406, states[0] = -95.018314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252506623, states[0] = 28.447294, states[40]= 0.109114
Saving checkpoint... 
Iteration: 1264459197, states[0] = -95.022067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276441615, states[0] = -95.019082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288147318, states[0] = -79.709710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300150082, states[0] = -84.721291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312086685, states[0] = -10.272186, states[40]= 0.002378
Saving checkpoint... 
Iteration: 1323994043, states[0] = -95.026657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335570092, states[0] = 1.666520, states[40]= 0.004663
Saving checkpoint... 
Iteration: 1347461392, states[0] = -95.022358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359410503, states[0] = -95.012404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371012825, states[0] = 24.428272, states[40]= 0.029241
Saving checkpoint... 
Iteration: 1382977695, states[0] = -95.024644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394470253, states[0] = -95.023629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406033645, states[0] = 17.939890, states[40]= 0.006236
Saving checkpoint... 
Iteration: 1418005107, states[0] = 31.412460, states[40]= 0.136854
Saving checkpoint... 
Iteration: 1429637524, states[0] = -64.419989, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1441686512, states[0] = -94.816290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453675550, states[0] = -94.789521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465249028, states[0] = -94.917253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477303785, states[0] = -94.967037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488855778, states[0] = -94.994776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1500847297, states[0] = -95.188493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512461967, states[0] = -95.071378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524533673, states[0] = -95.209540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536467719, states[0] = -95.104019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548470268, states[0] = -95.116726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560478137, states[0] = -95.139200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572451483, states[0] = -95.065648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584444270, states[0] = -94.930000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596431025, states[0] = -87.689281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608424264, states[0] = -75.178914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1620532840, states[0] = -95.238297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632230201, states[0] = -95.235579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644269635, states[0] = -95.275495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1656322146, states[0] = 20.952426, states[40]= 0.010405
Saving checkpoint... 
Iteration: 1668299102, states[0] = -95.296236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680329048, states[0] = 17.948546, states[40]= 0.007912
Saving checkpoint... 
Iteration: 1692306743, states[0] = 29.212409, states[40]= 0.098840
Saving checkpoint... 
Iteration: 1703808911, states[0] = -52.685004, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1715351448, states[0] = -95.259982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726989844, states[0] = -95.173750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738569598, states[0] = -7.412020, states[40]= 0.003366
Saving checkpoint... 
Iteration: 1750496007, states[0] = -95.294657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762101602, states[0] = -95.195018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774115859, states[0] = -95.217387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785762145, states[0] = -95.112204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1797655476, states[0] = 3.630548, states[40]= 0.005489
Saving checkpoint... 
Iteration: 1809501994, states[0] = 46.512385, states[40]= 0.099918
Saving checkpoint... 
Iteration: 1821366153, states[0] = -95.033047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833441059, states[0] = -95.043463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845418746, states[0] = -95.031735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856988855, states[0] = -95.038446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868986446, states[0] = -95.034458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880979373, states[0] = -95.030953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1892920521, states[0] = -95.018973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904894166, states[0] = -95.010969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916867113, states[0] = -95.001219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928881682, states[0] = -95.005562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940497261, states[0] = -95.027800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952392412, states[0] = -95.008028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963963813, states[0] = -95.022936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975904829, states[0] = -95.011010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987431701, states[0] = -95.017035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1998915688, states[0] = -95.013461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010441062, states[0] = -95.018678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022421828, states[0] = -95.014733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034335979, states[0] = -94.985544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046174166, states[0] = -94.783731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058160181, states[0] = -94.076117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069686359, states[0] = -94.815596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081256733, states[0] = -94.925664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093120439, states[0] = -44.000572, states[40]= 0.000073
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.902701
 - CaMKt in component CaMK (millimolar): 0.006841
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.843319
 - nass in component intracellular_ions (millimolar): 6.843379
 - ki in component intracellular_ions (millimolar): 145.134185
 - kss in component intracellular_ions (millimolar): 145.134165
 - cansr in component intracellular_ions (millimolar): 1.315753
 - cajsr in component intracellular_ions (millimolar): 1.278589
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880016
 - hs in component INa (dimensionless): 0.880011
 - j in component INa (dimensionless): 0.879985
 - hsp in component INa (dimensionless): 0.725860
 - jp in component INa (dimensionless): 0.879967
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.711566
 - hLp in component INaL (dimensionless): 0.457019
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.627293
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.702869
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935821
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001637
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337863
 - xs1 in component IKs (dimensionless): 0.235117
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:04:58 (237441): called boinc_finish(0)

</stderr_txt>
]]>


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