𝕏

Task 54928999

Name HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122_0
Workunit 26082712
Created 27 Jun 2024, 3:50:46 UTC
Sent 27 Jun 2024, 5:13:41 UTC
Report deadline 30 Jun 2024, 14:49:41 UTC
Received 27 Jun 2024, 20:46:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218427
Run time 2 hours 43 min 58 sec
CPU time 2 hours 35 min 53 sec
Validate state Valid
Credit 57.54
Device peak FLOPS 4.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.02 MB
Peak swap size 32.57 GB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.16.19</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122_0_r360585973_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122_0_r360585973_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.057184
     * GNaL_b in INaL: 0.006149
     * Gto_b in Ito: 0.084385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033124
     * GKs_b in IKs: 0.001789
     * GK1_b in IK1: 0.174687
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 69.266402
     * GKb_b in IKb: 0.003883
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040809
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13200073, states[0] = -95.161577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26378883, states[0] = -95.281379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39798095, states[0] = -95.225151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53113117, states[0] = -35.143954, states[40]= 0.000254
Saving checkpoint... 
Iteration: 66511070, states[0] = 22.819162, states[40]= 0.041485
Saving checkpoint... 
Iteration: 79845371, states[0] = -95.230081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93117299, states[0] = -38.360952, states[40]= 0.000165
Saving checkpoint... 
Iteration: 106466945, states[0] = -95.257449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119858192, states[0] = -95.229056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133178870, states[0] = -95.031860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146562302, states[0] = 6.329768, states[40]= 0.004823
Saving checkpoint... 
Iteration: 159915742, states[0] = -95.244617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173178009, states[0] = -95.027847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186538807, states[0] = 15.752093, states[40]= 0.005338
Saving checkpoint... 
Iteration: 199975946, states[0] = -95.254649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213316697, states[0] = -95.206135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226653972, states[0] = -87.717708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239946577, states[0] = -95.249947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253311175, states[0] = -95.202625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266633029, states[0] = -55.383927, states[40]= 0.000012
Saving checkpoint... 
Iteration: 280041816, states[0] = 14.661754, states[40]= 0.005205
Saving checkpoint... 
Iteration: 293402981, states[0] = -95.240504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306649958, states[0] = -80.270489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319905375, states[0] = -95.241092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333098641, states[0] = -19.434777, states[40]= 0.001010
Saving checkpoint... 
Iteration: 346419437, states[0] = -95.244424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359802209, states[0] = -95.196655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373137099, states[0] = -60.376685, states[40]= 0.000005
Saving checkpoint... 
Iteration: 386456754, states[0] = -95.251453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399793953, states[0] = -95.190765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413135563, states[0] = -58.458349, states[40]= 0.000007
Saving checkpoint... 
Iteration: 426480080, states[0] = -95.254753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439813349, states[0] = -95.203783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453178920, states[0] = -95.029684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466495422, states[0] = -95.256553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479848713, states[0] = -95.221992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493193861, states[0] = -95.062447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506535568, states[0] = 16.892732, states[40]= 0.005538
Saving checkpoint... 
Iteration: 519889823, states[0] = -95.236700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533197189, states[0] = -95.068916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546531394, states[0] = 18.261715, states[40]= 0.005929
Saving checkpoint... 
Iteration: 559847258, states[0] = -95.221307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573223654, states[0] = -95.114500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586588303, states[0] = -9.681146, states[40]= 0.002422
Saving checkpoint... 
Iteration: 599925145, states[0] = -95.245500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613270846, states[0] = -95.171362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626366153, states[0] = -95.228850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639090369, states[0] = -11.533927, states[40]= 0.002052
Saving checkpoint... 
Iteration: 651955247, states[0] = -95.251041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664754769, states[0] = -95.154963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677763358, states[0] = -95.164035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690860853, states[0] = -95.226816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703985119, states[0] = -95.255203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716784112, states[0] = -95.182905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730094188, states[0] = -15.121868, states[40]= 0.001461
Saving checkpoint... 
Iteration: 743488990, states[0] = -95.255641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756825964, states[0] = -95.210813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770173693, states[0] = -95.007861, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122_0_r360585973_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627055043973765_ORdGradInc_k_24-Pueyo_APDR-conf_122_0_r360585973_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.057184
     * GNaL_b in INaL: 0.006149
     * Gto_b in Ito: 0.084385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033124
     * GKs_b in IKs: 0.001789
     * GK1_b in IK1: 0.174687
     * Gncx_b in INaCa_i: 0.000950
     * Pnak_b in INaK: 69.266402
     * GKb_b in IKb: 0.003883
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040809
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 770173693
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -95.007861 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 783585123, states[0] = -7.003861, states[40]= 0.002997
Saving checkpoint... 
Iteration: 797381847, states[0] = -95.234090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811100530, states[0] = -21.274420, states[40]= 0.000887
Saving checkpoint... 
Iteration: 824524304, states[0] = 20.272523, states[40]= 0.007356
Saving checkpoint... 
Iteration: 837911139, states[0] = -95.242178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851396756, states[0] = -95.238460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864439507, states[0] = -95.248183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878083844, states[0] = -5.995248, states[40]= 0.003214
Saving checkpoint... 
Iteration: 891610000, states[0] = -30.545698, states[40]= 0.000438
Saving checkpoint... 
Iteration: 905158400, states[0] = -92.796035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918453563, states[0] = -95.250598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932052101, states[0] = 10.686369, states[40]= 0.004978
Saving checkpoint... 
Iteration: 945780797, states[0] = -95.180002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959459216, states[0] = -95.251471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973043026, states[0] = 14.211100, states[40]= 0.005164
Saving checkpoint... 
Iteration: 986681741, states[0] = -95.036588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000411292, states[0] = -95.242111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014055213, states[0] = 9.417038, states[40]= 0.004937
Saving checkpoint... 
Iteration: 1027889659, states[0] = -95.236326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041655964, states[0] = -90.535302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055470696, states[0] = -95.253097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069202229, states[0] = -95.078091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082864790, states[0] = -95.228054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096648382, states[0] = -77.295107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110390675, states[0] = -95.236571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124303876, states[0] = -95.197287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138044440, states[0] = 13.677623, states[40]= 0.005122
Saving checkpoint... 
Iteration: 1151846835, states[0] = -95.220741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165573777, states[0] = 0.638587, states[40]= 0.004363
Saving checkpoint... 
Iteration: 1179375561, states[0] = -95.231796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193030867, states[0] = 18.426055, states[40]= 0.005993
Saving checkpoint... 
Iteration: 1206728101, states[0] = -95.120699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220450731, states[0] = -95.249936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234188006, states[0] = -95.050127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247875427, states[0] = -95.231707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261584149, states[0] = -6.231894, states[40]= 0.003164
Saving checkpoint... 
Iteration: 1275174646, states[0] = -95.013078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288776384, states[0] = -95.175966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302296919, states[0] = -95.192346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316013725, states[0] = 22.384583, states[40]= 0.023586
Saving checkpoint... 
Iteration: 1329641146, states[0] = -65.724202, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1343377141, states[0] = -95.232217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357068012, states[0] = 3.675814, states[40]= 0.004661
Saving checkpoint... 
Iteration: 1370775999, states[0] = -95.175572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384459710, states[0] = -95.251275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398190059, states[0] = -95.054239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411816585, states[0] = -95.205100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425430903, states[0] = -95.246160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439194749, states[0] = -95.063585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452930198, states[0] = -95.246000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466661768, states[0] = -94.255011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480372071, states[0] = -95.230412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494080153, states[0] = -3.310507, states[40]= 0.003754
Saving checkpoint... 
Iteration: 1507684780, states[0] = -95.337994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521151739, states[0] = -95.250618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1534824774, states[0] = 19.410410, states[40]= 0.008401
Saving checkpoint... 
Iteration: 1548448732, states[0] = -95.245152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561913636, states[0] = -56.547777, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1575507333, states[0] = -95.417479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1589010290, states[0] = -95.424314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602428933, states[0] = -82.558944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615562908, states[0] = -0.853331, states[40]= 0.004690
Saving checkpoint... 
Iteration: 1628999292, states[0] = -95.512907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641946730, states[0] = 8.991040, states[40]= 0.005747
Saving checkpoint... 
Iteration: 1655262704, states[0] = -95.332911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668524191, states[0] = -95.447625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681782253, states[0] = -95.503124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695133895, states[0] = -91.297666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708463220, states[0] = -95.488772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721676362, states[0] = -95.499080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735101117, states[0] = -95.413740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748561301, states[0] = -95.329615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761956235, states[0] = 3.554966, states[40]= 0.005276
Saving checkpoint... 
Iteration: 1775386449, states[0] = -95.506054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788963037, states[0] = -1.005635, states[40]= 0.004665
Saving checkpoint... 
Iteration: 1802432863, states[0] = -95.302709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815850213, states[0] = -95.261151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829231905, states[0] = -95.153425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842491256, states[0] = -95.273914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1855715918, states[0] = -95.114515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869026637, states[0] = 19.547677, states[40]= 0.006690
Saving checkpoint... 
Iteration: 1882360483, states[0] = -95.231750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895656602, states[0] = -91.604302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1908947916, states[0] = -95.251688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922263810, states[0] = -95.165522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1935567707, states[0] = 3.789325, states[40]= 0.004671
Saving checkpoint... 
Iteration: 1948805547, states[0] = -95.198683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962181951, states[0] = -95.037004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975495562, states[0] = -95.255946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988786030, states[0] = -95.183860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002102106, states[0] = -22.823096, states[40]= 0.000803
Saving checkpoint... 
Iteration: 2015355243, states[0] = -95.223816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028607563, states[0] = -28.151520, states[40]= 0.000551
Saving checkpoint... 
Iteration: 2041887193, states[0] = -95.234944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055096973, states[0] = -17.813780, states[40]= 0.001148
Saving checkpoint... 
Iteration: 2068179048, states[0] = -95.028969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081431187, states[0] = -95.245758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094699808, states[0] = -95.072857, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.131831
 - CaMKt in component CaMK (millimolar): 0.007015
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.538580
 - nass in component intracellular_ions (millimolar): 6.538641
 - ki in component intracellular_ions (millimolar): 145.437727
 - kss in component intracellular_ions (millimolar): 145.437706
 - cansr in component intracellular_ions (millimolar): 1.317255
 - cajsr in component intracellular_ions (millimolar): 1.279395
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003535
 - hf in component INa (dimensionless): 0.883934
 - hs in component INa (dimensionless): 0.883930
 - j in component INa (dimensionless): 0.883905
 - hsp in component INa (dimensionless): 0.733288
 - jp in component INa (dimensionless): 0.883888
 - mL in component INaL (dimensionless): 0.000047
 - hL in component INaL (dimensionless): 0.716938
 - hLp in component INaL (dimensionless): 0.461930
 - a in component Ito (dimensionless): 0.000614
 - iF in component Ito (dimensionless): 0.999875
 - iS in component Ito (dimensionless): 0.626002
 - ap in component Ito (dimensionless): 0.000313
 - iFp in component Ito (dimensionless): 0.999875
 - iSp in component Ito (dimensionless): 0.701996
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936073
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001629
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326201
 - xs1 in component IKs (dimensionless): 0.239095
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997276
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:46:08 (83475): called boinc_finish(0)

</stderr_txt>
]]>


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