𝕏

Task 54928801

Name HuVeMOp_20240627054547981351_ORdGradInc_k_24-Pueyo_APDR-conf_352_0
Workunit 26082614
Created 27 Jun 2024, 3:45:49 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 7:31:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 41 sec
CPU time 1 hours 27 min 30 sec
Validate state Valid
Credit 59.58
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627054547981351_ORdGradInc_k_24-Pueyo_APDR-conf_352.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627054547981351_ORdGradInc_k_24-Pueyo_APDR-conf_352_0_r345952858_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627054547981351_ORdGradInc_k_24-Pueyo_APDR-conf_352_0_r345952858_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.682943
     * GNaL_b in INaL: 0.005443
     * Gto_b in Ito: 0.087631
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.033034
     * GKs_b in IKs: 0.001845
     * GK1_b in IK1: 0.151439
     * Gncx_b in INaCa_i: 0.000955
     * Pnak_b in INaK: 65.975819
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042111
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12424191, states[0] = -94.977766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23988476, states[0] = -94.966682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35988360, states[0] = -94.953373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47838198, states[0] = -94.900739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59737449, states[0] = -94.797597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71263052, states[0] = -94.828675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83281856, states[0] = -94.846259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95186783, states[0] = -94.688254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106705109, states[0] = -94.728676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118570095, states[0] = 1.664504, states[40]= 0.004473
Saving checkpoint... 
Iteration: 130599121, states[0] = -21.708602, states[40]= 0.000862
Saving checkpoint... 
Iteration: 142476909, states[0] = -94.925829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154431267, states[0] = -94.916989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166384159, states[0] = -94.903120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177913486, states[0] = -94.912116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189840906, states[0] = -94.883577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201719737, states[0] = -94.754162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213646241, states[0] = -71.797292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 225251101, states[0] = -94.803943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236769803, states[0] = -94.826912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248473479, states[0] = -94.924097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260294329, states[0] = -94.851023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272287821, states[0] = -94.845170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283792801, states[0] = -94.849651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295782835, states[0] = -94.840400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307703066, states[0] = -94.720818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319669941, states[0] = -94.424393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331611587, states[0] = -33.741719, states[40]= 0.000304
Saving checkpoint... 
Iteration: 343556039, states[0] = 8.351095, states[40]= 0.004863
Saving checkpoint... 
Iteration: 355476634, states[0] = -94.924441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367400545, states[0] = -94.907814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379364125, states[0] = -94.894447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391342133, states[0] = -94.883788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403279332, states[0] = -94.836830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415231610, states[0] = -94.774517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427146434, states[0] = -72.051152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438898639, states[0] = -94.907170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450887050, states[0] = -94.903334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462473002, states[0] = -94.923812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474067006, states[0] = 3.323730, states[40]= 0.004618
Saving checkpoint... 
Iteration: 485950774, states[0] = -94.919983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497537992, states[0] = 15.411123, states[40]= 0.005247
Saving checkpoint... 
Iteration: 509517567, states[0] = 21.106278, states[40]= 0.012025
Saving checkpoint... 
Iteration: 521496440, states[0] = -94.926992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533494871, states[0] = -94.926790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545476519, states[0] = -94.924284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 557332028, states[0] = -94.877952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568851158, states[0] = -94.888305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580364920, states[0] = -94.894644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591920466, states[0] = -94.913217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603462154, states[0] = -94.921951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614965443, states[0] = -94.922495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626529716, states[0] = 18.165092, states[40]= 0.005920
Saving checkpoint... 
Iteration: 638421963, states[0] = -94.913561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650384604, states[0] = -94.902326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661865099, states[0] = -94.894661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673762727, states[0] = -94.818326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685248899, states[0] = -94.800482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697141845, states[0] = -66.087012, states[40]= 0.000002
Saving checkpoint... 
Iteration: 709139164, states[0] = -62.897149, states[40]= 0.000003
Saving checkpoint... 
Iteration: 721056085, states[0] = 8.331715, states[40]= 0.004862
Saving checkpoint... 
Iteration: 733028806, states[0] = 18.437250, states[40]= 0.006045
Saving checkpoint... 
Iteration: 744979791, states[0] = -94.924618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 756922614, states[0] = -94.913637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768847577, states[0] = -94.886365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780807072, states[0] = -94.860965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792736190, states[0] = -94.781621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804711545, states[0] = -94.737820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816695973, states[0] = -94.705026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828318016, states[0] = -94.868826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840208241, states[0] = -94.731158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852154677, states[0] = -84.744250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864166163, states[0] = -93.984068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876120053, states[0] = -42.194399, states[40]= 0.000094
Saving checkpoint... 
Iteration: 888082574, states[0] = -6.367448, states[40]= 0.003139
Saving checkpoint... 
Iteration: 900034826, states[0] = 16.517198, states[40]= 0.005432
Saving checkpoint... 
Iteration: 912022034, states[0] = 20.211077, states[40]= 0.007917
Saving checkpoint... 
Iteration: 923595302, states[0] = -17.914287, states[40]= 0.001140
Saving checkpoint... 
Iteration: 935154616, states[0] = -84.649801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 946726254, states[0] = -94.765064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958639965, states[0] = -63.833267, states[40]= 0.000003
Saving checkpoint... 
Iteration: 970634515, states[0] = -57.648837, states[40]= 0.000008
Saving checkpoint... 
Iteration: 982442743, states[0] = -94.918033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994403519, states[0] = -94.908256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005865131, states[0] = -94.894425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017825325, states[0] = -94.873500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029367402, states[0] = -94.895375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040908083, states[0] = -94.909554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052863740, states[0] = -94.893789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064815393, states[0] = -94.866839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076394044, states[0] = -94.905240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088346025, states[0] = -94.885335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099867448, states[0] = -94.895343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111351325, states[0] = -94.887993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122957660, states[0] = -94.920789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134955083, states[0] = -94.920315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146519641, states[0] = 20.718642, states[40]= 0.009546
Saving checkpoint... 
Iteration: 1158463028, states[0] = -94.921696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170450167, states[0] = -94.919370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182413623, states[0] = -94.910993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193943732, states[0] = -94.918082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206336435, states[0] = -94.880042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217985606, states[0] = -94.925088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230503825, states[0] = 31.785786, states[40]= 0.166991
Saving checkpoint... 
Iteration: 1242587701, states[0] = -10.715728, states[40]= 0.002216
Saving checkpoint... 
Iteration: 1254329521, states[0] = -94.875937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266485934, states[0] = -94.925098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278113971, states[0] = -36.084595, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1290279809, states[0] = -94.836664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302297083, states[0] = -94.852578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314491233, states[0] = -94.925763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326478245, states[0] = -94.923971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338461474, states[0] = -94.921301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350494028, states[0] = -94.926092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362474235, states[0] = -94.923347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374469460, states[0] = -94.922596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386060898, states[0] = 6.225479, states[40]= 0.004788
Saving checkpoint... 
Iteration: 1397954831, states[0] = -94.920078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410216162, states[0] = -94.746350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422383967, states[0] = -94.901537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434253565, states[0] = -94.806240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446315855, states[0] = -94.866885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458282825, states[0] = -94.839528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469780033, states[0] = -94.836758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481758088, states[0] = -94.812034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493686422, states[0] = -94.681371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505713221, states[0] = 22.592595, states[40]= 0.027578
Saving checkpoint... 
Iteration: 1517685369, states[0] = -95.179426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529217842, states[0] = -61.060745, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1541130784, states[0] = 16.452264, states[40]= 0.006807
Saving checkpoint... 
Iteration: 1553208476, states[0] = -50.602801, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1564817865, states[0] = 20.989826, states[40]= 0.013095
Saving checkpoint... 
Iteration: 1576799894, states[0] = -95.229126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588857159, states[0] = 2.365338, states[40]= 0.005130
Saving checkpoint... 
Iteration: 1600811753, states[0] = 22.638821, states[40]= 0.036080
Saving checkpoint... 
Iteration: 1612840910, states[0] = 11.467499, states[40]= 0.005943
Saving checkpoint... 
Iteration: 1624495096, states[0] = -95.231799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636323082, states[0] = -70.354781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1648277212, states[0] = -15.674485, states[40]= 0.001564
Saving checkpoint... 
Iteration: 1660293031, states[0] = -33.466826, states[40]= 0.000312
Saving checkpoint... 
Iteration: 1671782909, states[0] = -95.078475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683379341, states[0] = -18.092160, states[40]= 0.001245
Saving checkpoint... 
Iteration: 1695318477, states[0] = 20.723110, states[40]= 0.012198
Saving checkpoint... 
Iteration: 1706818810, states[0] = -64.477173, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1718377033, states[0] = -95.219368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730451830, states[0] = 5.533244, states[40]= 0.005439
Saving checkpoint... 
Iteration: 1742405887, states[0] = 26.968158, states[40]= 0.124627
Saving checkpoint... 
Iteration: 1754287000, states[0] = -95.088334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766271417, states[0] = -95.049542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778274663, states[0] = -95.058146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790171124, states[0] = -9.130164, states[40]= 0.002870
Saving checkpoint... 
Iteration: 1801739911, states[0] = -94.857980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813276199, states[0] = -94.884488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1825299781, states[0] = -94.893051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837190840, states[0] = -94.720251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849174883, states[0] = -94.639052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861139352, states[0] = -64.095054, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1873328407, states[0] = -94.884469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884908347, states[0] = -94.915877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897009471, states[0] = 22.668175, states[40]= 0.059762
Saving checkpoint... 
Iteration: 1908689315, states[0] = -94.692179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920681709, states[0] = -94.667578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1932627094, states[0] = -49.695449, states[40]= 0.000029
Saving checkpoint... 
Iteration: 1944199386, states[0] = -94.712927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956134842, states[0] = -58.067816, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1968114994, states[0] = -37.130756, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1980070785, states[0] = 1.336612, states[40]= 0.004437
Saving checkpoint... 
Iteration: 1992166476, states[0] = -94.042564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004176222, states[0] = -94.623814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015737815, states[0] = -94.783361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027752145, states[0] = -94.803967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039742520, states[0] = -94.790382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051729195, states[0] = -94.769282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063276680, states[0] = -94.832876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075235896, states[0] = -94.780182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087221060, states[0] = -94.754939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099245458, states[0] = -94.794548, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.802098
 - CaMKt in component CaMK (millimolar): 0.007183
 - cass in component intracellular_ions (millimolar): 0.000075
 - nai in component intracellular_ions (millimolar): 6.719096
 - nass in component intracellular_ions (millimolar): 6.719156
 - ki in component intracellular_ions (millimolar): 145.253767
 - kss in component intracellular_ions (millimolar): 145.253747
 - cansr in component intracellular_ions (millimolar): 1.329598
 - cajsr in component intracellular_ions (millimolar): 1.291778
 - cai in component intracellular_ions (millimolar): 0.000076
 - m in component INa (dimensionless): 0.003655
 - hf in component INa (dimensionless): 0.878259
 - hs in component INa (dimensionless): 0.878254
 - j in component INa (dimensionless): 0.878224
 - hsp in component INa (dimensionless): 0.722556
 - jp in component INa (dimensionless): 0.878204
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707894
 - hLp in component INaL (dimensionless): 0.450829
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.624094
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.699586
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.938609
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999897
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001672
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.324173
 - xs1 in component IKs (dimensionless): 0.234599
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997363
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:32:39 (232979): called boinc_finish(0)

</stderr_txt>
]]>


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