𝕏

Task 54928637

Name HuVeMOp_20240627053547321039_ORdGradInc_k_24-Pueyo_APDR-conf_974_0
Workunit 26082535
Created 27 Jun 2024, 3:35:54 UTC
Sent 27 Jun 2024, 5:23:34 UTC
Report deadline 30 Jun 2024, 14:59:34 UTC
Received 28 Jun 2024, 4:34:20 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 29 min 12 sec
CPU time 1 hours 27 min 45 sec
Validate state Valid
Credit 62.07
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627053547321039_ORdGradInc_k_24-Pueyo_APDR-conf_974.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627053547321039_ORdGradInc_k_24-Pueyo_APDR-conf_974_0_r1403507284_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627053547321039_ORdGradInc_k_24-Pueyo_APDR-conf_974_0_r1403507284_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.399337
     * GNaL_b in INaL: 0.008915
     * Gto_b in Ito: 0.076802
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033752
     * GKs_b in IKs: 0.001753
     * GK1_b in IK1: 0.153219
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 62.855693
     * GKb_b in IKb: 0.003851
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038713
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11844821, states[0] = -94.986954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23807775, states[0] = -94.948151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35345004, states[0] = -94.963718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47301131, states[0] = -94.930168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59267418, states[0] = -94.894423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70815491, states[0] = -94.935738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81969828, states[0] = -94.990518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93828103, states[0] = -94.941522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105752845, states[0] = -94.870987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117580027, states[0] = -0.524747, states[40]= 0.004237
Saving checkpoint... 
Iteration: 129524803, states[0] = 21.655486, states[40]= 0.007428
Saving checkpoint... 
Iteration: 141008887, states[0] = 25.415945, states[40]= 0.068504
Saving checkpoint... 
Iteration: 153022025, states[0] = 22.334615, states[40]= 0.008613
Saving checkpoint... 
Iteration: 164492377, states[0] = -94.990296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176409903, states[0] = -94.974036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188357016, states[0] = -94.954560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199834755, states[0] = -94.942888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211243213, states[0] = -94.855663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223177658, states[0] = -94.620421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235102566, states[0] = -18.309235, states[40]= 0.001123
Saving checkpoint... 
Iteration: 246909690, states[0] = -94.973712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258487322, states[0] = -94.989239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270461396, states[0] = -94.985248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282416881, states[0] = -94.975635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294304563, states[0] = -94.922280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306278979, states[0] = -94.899383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318264762, states[0] = -94.883822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329820185, states[0] = -94.933585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341420111, states[0] = -94.976429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353385746, states[0] = -94.966012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365321058, states[0] = -94.934143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377270172, states[0] = -94.889968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389250504, states[0] = -94.865736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401234545, states[0] = -94.842230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412777085, states[0] = -94.897368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424676305, states[0] = -94.561952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436286096, states[0] = -94.906272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448207087, states[0] = -94.792908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459696466, states[0] = -94.770894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471241230, states[0] = -94.852480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483194910, states[0] = -94.767403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495127547, states[0] = -42.035891, states[40]= 0.000106
Saving checkpoint... 
Iteration: 506942411, states[0] = -94.981479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518449954, states[0] = -94.982983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530043445, states[0] = 15.669987, states[40]= 0.005275
Saving checkpoint... 
Iteration: 541985996, states[0] = -94.988860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553888548, states[0] = -94.966868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565052869, states[0] = 12.085627, states[40]= 0.005086
Saving checkpoint... 
Iteration: 576740653, states[0] = -94.851552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588750410, states[0] = -94.865484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600726842, states[0] = -94.829409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611967023, states[0] = -94.985969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623522682, states[0] = 22.186655, states[40]= 0.008272
Saving checkpoint... 
Iteration: 635387139, states[0] = -94.966328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646890265, states[0] = -94.967400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658798484, states[0] = -94.917133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670770599, states[0] = -94.890260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682797777, states[0] = -94.916527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694732170, states[0] = -94.838229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706688785, states[0] = -94.751053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718582545, states[0] = -2.013891, states[40]= 0.004002
Saving checkpoint... 
Iteration: 730524500, states[0] = 21.742457, states[40]= 0.007531
Saving checkpoint... 
Iteration: 742056021, states[0] = 10.833656, states[40]= 0.005048
Saving checkpoint... 
Iteration: 753184123, states[0] = -94.728996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765081053, states[0] = -1.094818, states[40]= 0.004151
Saving checkpoint... 
Iteration: 777005596, states[0] = 29.017129, states[40]= 0.134329
Saving checkpoint... 
Iteration: 788971242, states[0] = -94.986539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800569020, states[0] = 5.234238, states[40]= 0.004815
Saving checkpoint... 
Iteration: 812473558, states[0] = -94.986886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824427041, states[0] = -94.977848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836429011, states[0] = -94.978310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847921590, states[0] = -94.976491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860189759, states[0] = -94.754022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871809352, states[0] = -94.925578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883747448, states[0] = -94.861212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895704349, states[0] = -94.787134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907682523, states[0] = -94.715567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919639795, states[0] = -55.713934, states[40]= 0.000012
Saving checkpoint... 
Iteration: 931529693, states[0] = 20.309941, states[40]= 0.006338
Saving checkpoint... 
Iteration: 943425786, states[0] = -94.977472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955372614, states[0] = -94.960675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966901400, states[0] = -94.970795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978896736, states[0] = -94.969329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990796197, states[0] = -94.915000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002852384, states[0] = -94.951662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014362540, states[0] = -94.956383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026274414, states[0] = -94.894182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037832731, states[0] = -94.941053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049769737, states[0] = -94.889066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061898916, states[0] = -94.969968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073454674, states[0] = -94.983533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085035491, states[0] = 18.472341, states[40]= 0.005694
Saving checkpoint... 
Iteration: 1096632826, states[0] = -47.726326, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1108133038, states[0] = -47.962662, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1120101821, states[0] = -17.618559, states[40]= 0.001184
Saving checkpoint... 
Iteration: 1131931482, states[0] = -94.978703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143579502, states[0] = -0.178583, states[40]= 0.004285
Saving checkpoint... 
Iteration: 1155583440, states[0] = -2.584363, states[40]= 0.003903
Saving checkpoint... 
Iteration: 1167537527, states[0] = 17.780785, states[40]= 0.005549
Saving checkpoint... 
Iteration: 1179088236, states[0] = -5.918826, states[40]= 0.003238
Saving checkpoint... 
Iteration: 1190647065, states[0] = -64.537214, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1202614536, states[0] = -29.381676, states[40]= 0.000539
Saving checkpoint... 
Iteration: 1214560677, states[0] = 8.921286, states[40]= 0.004989
Saving checkpoint... 
Iteration: 1226572560, states[0] = 3.529753, states[40]= 0.004691
Saving checkpoint... 
Iteration: 1238245847, states[0] = -94.858731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250112493, states[0] = -27.480237, states[40]= 0.000635
Saving checkpoint... 
Iteration: 1261967871, states[0] = -94.985708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273832050, states[0] = -94.940503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285367339, states[0] = -94.958294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297267360, states[0] = -94.886225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308745617, states[0] = -94.858359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320649250, states[0] = -67.385892, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1332633390, states[0] = -48.356089, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1344034625, states[0] = 18.760018, states[40]= 0.005765
Saving checkpoint... 
Iteration: 1355607819, states[0] = -23.157254, states[40]= 0.000836
Saving checkpoint... 
Iteration: 1367549780, states[0] = 13.285590, states[40]= 0.005129
Saving checkpoint... 
Iteration: 1379123647, states[0] = -38.082937, states[40]= 0.000187
Saving checkpoint... 
Iteration: 1391151524, states[0] = -70.518991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402741105, states[0] = -94.851716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414751527, states[0] = -94.866483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426331337, states[0] = -94.939982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437885242, states[0] = -94.965163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449877836, states[0] = -94.962419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461408278, states[0] = -94.972527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472899264, states[0] = -94.969823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484918009, states[0] = -94.975178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496932255, states[0] = -94.978655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508494845, states[0] = -25.702697, states[40]= 0.000694
Saving checkpoint... 
Iteration: 1520452268, states[0] = 8.331729, states[40]= 0.005679
Saving checkpoint... 
Iteration: 1532342521, states[0] = -95.209853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543832906, states[0] = 17.347161, states[40]= 0.006927
Saving checkpoint... 
Iteration: 1555785315, states[0] = -95.268098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567719398, states[0] = -95.197393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579249953, states[0] = 8.931498, states[40]= 0.005788
Saving checkpoint... 
Iteration: 1590821132, states[0] = -95.205491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602746910, states[0] = -94.137504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614545015, states[0] = -95.241207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626526704, states[0] = -95.217365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638493989, states[0] = -95.159444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650452406, states[0] = -94.891780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662409321, states[0] = -44.818562, states[40]= 0.000073
Saving checkpoint... 
Iteration: 1674391667, states[0] = -25.432299, states[40]= 0.000726
Saving checkpoint... 
Iteration: 1685918145, states[0] = -95.205356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697506633, states[0] = -41.671184, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1709445843, states[0] = 10.944432, states[40]= 0.005967
Saving checkpoint... 
Iteration: 1721348276, states[0] = -95.247251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732935421, states[0] = -82.152609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744819850, states[0] = 22.148668, states[40]= 0.011551
Saving checkpoint... 
Iteration: 1756667053, states[0] = -95.093690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1768264991, states[0] = -0.081430, states[40]= 0.004870
Saving checkpoint... 
Iteration: 1779784910, states[0] = -95.140273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791687801, states[0] = -21.354105, states[40]= 0.000971
Saving checkpoint... 
Iteration: 1803510458, states[0] = 24.371136, states[40]= 0.047269
Saving checkpoint... 
Iteration: 1815453017, states[0] = -95.032421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827404404, states[0] = -95.007182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838911405, states[0] = -94.999189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850385949, states[0] = -94.983854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862259700, states[0] = -94.890156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873764989, states[0] = -94.892722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885687880, states[0] = -94.754464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897625749, states[0] = -40.485800, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1909562709, states[0] = 7.991498, states[40]= 0.004958
Saving checkpoint... 
Iteration: 1921505064, states[0] = 30.218641, states[40]= 0.144031
Saving checkpoint... 
Iteration: 1933423558, states[0] = -94.977989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945363061, states[0] = -94.957215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957318977, states[0] = -94.932583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968818805, states[0] = -94.932214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980796894, states[0] = -94.915374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992731137, states[0] = -94.836002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2004710853, states[0] = -94.799511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016267335, states[0] = -94.885859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027786363, states[0] = -94.905600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2039654493, states[0] = -74.952154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051224253, states[0] = -94.824041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063157417, states[0] = -79.693980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075056723, states[0] = 10.550193, states[40]= 0.005040
Saving checkpoint... 
Iteration: 2086591027, states[0] = -8.088221, states[40]= 0.002764
Saving checkpoint... 
Iteration: 2098750145, states[0] = -94.864145, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.865523
 - CaMKt in component CaMK (millimolar): 0.007116
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.831909
 - nass in component intracellular_ions (millimolar): 6.831971
 - ki in component intracellular_ions (millimolar): 145.143797
 - kss in component intracellular_ions (millimolar): 145.143777
 - cansr in component intracellular_ions (millimolar): 1.322004
 - cajsr in component intracellular_ions (millimolar): 1.283572
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003632
 - hf in component INa (dimensionless): 0.879369
 - hs in component INa (dimensionless): 0.879364
 - j in component INa (dimensionless): 0.879334
 - hsp in component INa (dimensionless): 0.724640
 - jp in component INa (dimensionless): 0.879314
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708162
 - hLp in component INaL (dimensionless): 0.448550
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.617032
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.690485
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929115
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999866
 - jca in component ICaL (dimensionless): 0.999975
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001652
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.346850
 - xs1 in component IKs (dimensionless): 0.251492
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997347
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:33:39 (232710): called boinc_finish(0)

</stderr_txt>
]]>


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