𝕏

Task 54927045

Name HuVeMOp_20240627050047585186_ORdGradInc_k_24-Pueyo_APDR-conf_252_1
Workunit 26081750
Created 27 Jun 2024, 3:00:52 UTC
Sent 27 Jun 2024, 4:48:45 UTC
Report deadline 30 Jun 2024, 14:24:45 UTC
Received 28 Jun 2024, 1:36:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 220412
Run time 2 hours 22 min 44 sec
CPU time 2 hours 11 min 5 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.73 MB
Peak swap size 5.18 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627050047585186_ORdGradInc_k_24-Pueyo_APDR-conf_252.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627050047585186_ORdGradInc_k_24-Pueyo_APDR-conf_252_1_r581221930_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627050047585186_ORdGradInc_k_24-Pueyo_APDR-conf_252_1_r581221930_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.672075
     * GNaL_b in INaL: 0.008049
     * Gto_b in Ito: 0.066689
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033750
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.164780
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 63.904893
     * GKb_b in IKb: 0.003874
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040236
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15035381, states[0] = 17.775719, states[40]= 0.005937
Saving checkpoint... 
Iteration: 29218474, states[0] = -95.013684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42987638, states[0] = -95.155406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57092852, states[0] = -12.163354, states[40]= 0.001946
Saving checkpoint... 
Iteration: 71168324, states[0] = -94.648042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85175320, states[0] = -94.880878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96017798, states[0] = 23.744946, states[40]= 0.013075
Saving checkpoint... 
Iteration: 109893476, states[0] = -95.121187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124148759, states[0] = -72.982813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138003482, states[0] = 36.671573, states[40]= 0.132943
Saving checkpoint... 
Iteration: 152259608, states[0] = -95.039577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166336832, states[0] = -95.097138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180427749, states[0] = -95.127346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194429095, states[0] = -95.127500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208337909, states[0] = -95.097261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222507195, states[0] = 27.838458, states[40]= 0.092985
Saving checkpoint... 
Iteration: 236630471, states[0] = -48.934084, states[40]= 0.000034
Saving checkpoint... 
Iteration: 250542987, states[0] = 15.550145, states[40]= 0.005440
Saving checkpoint... 
Iteration: 264713622, states[0] = -94.975765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278781237, states[0] = -95.059629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292927928, states[0] = -95.126963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307006961, states[0] = 28.093734, states[40]= 0.097369
Saving checkpoint... 
Iteration: 321388889, states[0] = -95.116969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335314513, states[0] = -95.084054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349448979, states[0] = -95.130975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363338687, states[0] = -95.097391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374892605, states[0] = -95.118047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389650605, states[0] = -75.814552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404336010, states[0] = -95.096038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419128704, states[0] = -46.903560, states[40]= 0.000047
Saving checkpoint... 
Iteration: 433777665, states[0] = -95.056375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448573589, states[0] = 2.079010, states[40]= 0.004583
Saving checkpoint... 
Iteration: 463153357, states[0] = -80.720075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477841920, states[0] = -95.098888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492385860, states[0] = -95.115936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506979356, states[0] = -95.135505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521574370, states[0] = 1.658669, states[40]= 0.004536
Saving checkpoint... 
Iteration: 536229109, states[0] = -94.999982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550920715, states[0] = -95.125230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565507450, states[0] = 27.585654, states[40]= 0.088308
Saving checkpoint... 
Iteration: 580372841, states[0] = -95.111552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595048947, states[0] = 13.183781, states[40]= 0.005251
Saving checkpoint... 
Iteration: 610109592, states[0] = -27.347985, states[40]= 0.000601
Saving checkpoint... 
Iteration: 621307003, states[0] = -95.079062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635968584, states[0] = -95.133947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650771708, states[0] = -95.050749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665445902, states[0] = -95.130260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680066931, states[0] = 5.417961, states[40]= 0.004868
Saving checkpoint... 
Iteration: 694790632, states[0] = -95.067140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707743214, states[0] = -95.019189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722607965, states[0] = -25.783712, states[40]= 0.000676
Saving checkpoint... 
Iteration: 737297201, states[0] = -95.072121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752055191, states[0] = 10.618037, states[40]= 0.005128
Saving checkpoint... 
Iteration: 767001964, states[0] = 45.475666, states[40]= 0.083492
Saving checkpoint... 
Iteration: 781767541, states[0] = -95.046620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796325455, states[0] = -95.090241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811114706, states[0] = -32.307358, states[40]= 0.000367
Saving checkpoint... 
Iteration: 825603833, states[0] = -21.825388, states[40]= 0.000868
Saving checkpoint... 
Iteration: 840471764, states[0] = -95.134294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855013209, states[0] = 24.895508, states[40]= 0.026313
Saving checkpoint... 
Iteration: 869603235, states[0] = -21.253185, states[40]= 0.000900
Saving checkpoint... 
Iteration: 884460807, states[0] = -95.132643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899002845, states[0] = 39.992586, states[40]= 0.118367
Saving checkpoint... 
Iteration: 913874585, states[0] = -95.111988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928559834, states[0] = 8.635601, states[40]= 0.005044
Saving checkpoint... 
Iteration: 943364938, states[0] = -95.108456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957889362, states[0] = -95.116769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972408411, states[0] = -95.122054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987336578, states[0] = -95.096014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002162233, states[0] = -92.832933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016973986, states[0] = -95.134511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031552628, states[0] = 11.683011, states[40]= 0.005174
Saving checkpoint... 
Iteration: 1046455211, states[0] = -95.131660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061042249, states[0] = 15.838094, states[40]= 0.005472
Saving checkpoint... 
Iteration: 1071938477, states[0] = -95.128666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087066807, states[0] = 5.476789, states[40]= 0.004872
Saving checkpoint... 
Iteration: 1101680297, states[0] = -94.906354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116353339, states[0] = -95.103688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131048747, states[0] = 13.264557, states[40]= 0.005256
Saving checkpoint... 
Iteration: 1145962827, states[0] = -95.132818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160665896, states[0] = -94.216175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175469775, states[0] = -95.133834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190339146, states[0] = -95.097175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205093323, states[0] = -11.898041, states[40]= 0.001988
Saving checkpoint... 
Iteration: 1219923692, states[0] = -95.125542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234855583, states[0] = -95.104571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246500442, states[0] = -39.038259, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1261143101, states[0] = -64.480703, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1275851869, states[0] = -95.102973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287343794, states[0] = -95.099342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301603798, states[0] = -21.791701, states[40]= 0.000870
Saving checkpoint... 
Iteration: 1316151380, states[0] = -77.159492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330482974, states[0] = -95.135537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345088400, states[0] = -7.646431, states[40]= 0.002869
Saving checkpoint... 
Iteration: 1359604328, states[0] = -22.298841, states[40]= 0.000843
Saving checkpoint... 
Iteration: 1374328165, states[0] = -95.091426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388900019, states[0] = -95.119617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403539515, states[0] = 16.886812, states[40]= 0.005615
Saving checkpoint... 
Iteration: 1414665459, states[0] = -94.116953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429424326, states[0] = -95.125570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444059690, states[0] = 8.698387, states[40]= 0.005046
Saving checkpoint... 
Iteration: 1458741014, states[0] = -95.015955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473327754, states[0] = -95.091150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487629916, states[0] = -48.286848, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1502253410, states[0] = -95.055552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517110411, states[0] = 26.450877, states[40]= 0.046831
Saving checkpoint... 
Iteration: 1531840741, states[0] = 13.660812, states[40]= 0.006329
Saving checkpoint... 
Iteration: 1546704147, states[0] = -95.295205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561304932, states[0] = -41.662697, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1575945779, states[0] = 10.747764, states[40]= 0.006022
Saving checkpoint... 
Iteration: 1590480352, states[0] = -95.262660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605238044, states[0] = -95.357007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620187107, states[0] = -95.279394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634948996, states[0] = -95.370545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649689497, states[0] = -95.404390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1664389560, states[0] = -95.404675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679410789, states[0] = 25.939160, states[40]= 0.043594
Saving checkpoint... 
Iteration: 1693820790, states[0] = 22.163019, states[40]= 0.011132
Saving checkpoint... 
Iteration: 1708374108, states[0] = -95.253044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1723149824, states[0] = -95.372350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1737642226, states[0] = 12.474369, states[40]= 0.006234
Saving checkpoint... 
Iteration: 1752134125, states[0] = -86.327119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762990787, states[0] = -95.288285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777329563, states[0] = -77.639838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1791382654, states[0] = -17.591719, states[40]= 0.001309
Saving checkpoint... 
Iteration: 1805287408, states[0] = -95.114743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816323738, states[0] = -95.129683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830429885, states[0] = -95.154888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844461231, states[0] = -95.151282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858375635, states[0] = -95.124682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1872377594, states[0] = -95.121114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886434122, states[0] = -95.133135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900429256, states[0] = -95.130236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914251295, states[0] = -95.031071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928967696, states[0] = -95.134834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1944681274, states[0] = -94.910784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1960557361, states[0] = 9.685949, states[40]= 0.005090
Saving checkpoint... 
Iteration: 1972119303, states[0] = -36.903098, states[40]= 0.000204
Saving checkpoint... 
Iteration: 1986865614, states[0] = -95.108456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000821887, states[0] = -95.087764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014719525, states[0] = -94.984613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028603476, states[0] = -21.489991, states[40]= 0.000886
Saving checkpoint... 
Iteration: 2042616233, states[0] = -33.811552, states[40]= 0.000306
Saving checkpoint... 
Iteration: 2056556518, states[0] = 10.058293, states[40]= 0.005105
Saving checkpoint... 
Iteration: 2070562857, states[0] = 7.297331, states[40]= 0.004979
Saving checkpoint... 
Iteration: 2084407168, states[0] = -95.121122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098325332, states[0] = -95.089449, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.012969
 - CaMKt in component CaMK (millimolar): 0.006686
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.720278
 - nass in component intracellular_ions (millimolar): 6.720338
 - ki in component intracellular_ions (millimolar): 145.261641
 - kss in component intracellular_ions (millimolar): 145.261620
 - cansr in component intracellular_ions (millimolar): 1.296877
 - cajsr in component intracellular_ions (millimolar): 1.259236
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003578
 - hf in component INa (dimensionless): 0.881915
 - hs in component INa (dimensionless): 0.881911
 - j in component INa (dimensionless): 0.881885
 - hsp in component INa (dimensionless): 0.729450
 - jp in component INa (dimensionless): 0.881867
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.713154
 - hLp in component INaL (dimensionless): 0.456266
 - a in component Ito (dimensionless): 0.000619
 - iF in component Ito (dimensionless): 0.999872
 - iS in component Ito (dimensionless): 0.621968
 - ap in component Ito (dimensionless): 0.000315
 - iFp in component Ito (dimensionless): 0.999872
 - iSp in component Ito (dimensionless): 0.696377
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930576
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999873
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001558
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340402
 - xs1 in component IKs (dimensionless): 0.246677
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997308
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:02:30 (10296): called boinc_finish(0)

</stderr_txt>
]]>