𝕏

Task 54925817

Name HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_779_1
Workunit 26081143
Created 27 Jun 2024, 2:40:51 UTC
Sent 27 Jun 2024, 4:28:56 UTC
Report deadline 30 Jun 2024, 14:04:56 UTC
Received 27 Jun 2024, 9:29:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217041
Run time 2 hours 50 min 20 sec
CPU time 2 hours 48 min 49 sec
Validate state Valid
Credit 58.26
Device peak FLOPS 3.79 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 4.10 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_779.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_779_1_r1631291339_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627044042218173_ORdGradInc_k_24-Pueyo_APDR-conf_779_1_r1631291339_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 94.557341
     * GNaL_b in INaL: 0.009020
     * Gto_b in Ito: 0.069058
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.032558
     * GKs_b in IKs: 0.001905
     * GK1_b in IK1: 0.156155
     * Gncx_b in INaCa_i: 0.000949
     * Pnak_b in INaK: 69.730090
     * GKb_b in IKb: 0.003902
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043640
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11682514, states[0] = -94.908125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23405794, states[0] = -95.094127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35273242, states[0] = -94.999199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47033491, states[0] = 19.677112, states[40]= 0.005908
Saving checkpoint... 
Iteration: 58818528, states[0] = -95.015241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70604511, states[0] = -18.455133, states[40]= 0.001111
Saving checkpoint... 
Iteration: 82369941, states[0] = -95.031691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94123970, states[0] = -35.933926, states[40]= 0.000254
Saving checkpoint... 
Iteration: 105907601, states[0] = -95.039351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117644769, states[0] = -58.049271, states[40]= 0.000008
Saving checkpoint... 
Iteration: 129395673, states[0] = -95.033440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140922135, states[0] = -95.039984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152655438, states[0] = -71.676139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164409843, states[0] = -95.035968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176185904, states[0] = -94.801061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187931879, states[0] = -95.040906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199669952, states[0] = -92.402790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211402918, states[0] = -95.033353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223191803, states[0] = -94.829265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234951084, states[0] = -95.044412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246747166, states[0] = -94.927200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258501238, states[0] = 47.836661, states[40]= 0.046474
Saving checkpoint... 
Iteration: 270241763, states[0] = -94.919669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281995434, states[0] = -95.050929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293756043, states[0] = -94.938559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305539049, states[0] = 18.108316, states[40]= 0.005494
Saving checkpoint... 
Iteration: 317304599, states[0] = -94.985739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329005725, states[0] = 29.685084, states[40]= 0.124867
Saving checkpoint... 
Iteration: 340770641, states[0] = -94.955239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352510803, states[0] = 25.776038, states[40]= 0.042351
Saving checkpoint... 
Iteration: 364247073, states[0] = -94.926929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376030343, states[0] = 21.022291, states[40]= 0.006295
Saving checkpoint... 
Iteration: 387795905, states[0] = -94.978859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399572344, states[0] = 4.678749, states[40]= 0.004759
Saving checkpoint... 
Iteration: 411342314, states[0] = -95.009299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423067401, states[0] = 6.943700, states[40]= 0.004897
Saving checkpoint... 
Iteration: 434832940, states[0] = -95.004210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446561531, states[0] = 9.460139, states[40]= 0.005003
Saving checkpoint... 
Iteration: 458254894, states[0] = -94.937018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469934804, states[0] = -95.040937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481225832, states[0] = -94.895085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492558892, states[0] = 10.544585, states[40]= 0.005038
Saving checkpoint... 
Iteration: 504269483, states[0] = -94.953901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516024658, states[0] = 22.661694, states[40]= 0.007543
Saving checkpoint... 
Iteration: 527795423, states[0] = -94.978379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539556742, states[0] = 11.410852, states[40]= 0.005064
Saving checkpoint... 
Iteration: 551307407, states[0] = -94.987674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563078710, states[0] = 1.480894, states[40]= 0.004466
Saving checkpoint... 
Iteration: 574825030, states[0] = -94.999466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586592886, states[0] = -7.687302, states[40]= 0.002826
Saving checkpoint... 
Iteration: 598373075, states[0] = -95.022936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610169723, states[0] = -92.234564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621922311, states[0] = -95.038013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633694682, states[0] = -94.836510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645461992, states[0] = -95.045962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657180887, states[0] = -94.714884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668944907, states[0] = -95.042882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680706906, states[0] = -94.861421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692429029, states[0] = -95.039539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704165849, states[0] = -88.291775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715939389, states[0] = -95.041754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727698576, states[0] = -94.845041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739445335, states[0] = -95.042924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751199720, states[0] = -94.847373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762947922, states[0] = -95.043406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774710864, states[0] = -94.868758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786480637, states[0] = -95.048703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798171168, states[0] = -93.071307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809933716, states[0] = -95.040506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821497392, states[0] = -95.050820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833261952, states[0] = -94.945294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844997950, states[0] = -95.050872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856746488, states[0] = -94.925847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868525621, states[0] = 22.402602, states[40]= 0.007249
Saving checkpoint... 
Iteration: 880267809, states[0] = -94.951867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891996729, states[0] = -95.050701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903746065, states[0] = -94.925245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915475258, states[0] = -95.047864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927233280, states[0] = -94.906689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938997115, states[0] = -95.050719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950737424, states[0] = -94.912935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962502306, states[0] = 42.980340, states[40]= 0.107466
Saving checkpoint... 
Iteration: 974275455, states[0] = -94.959854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986006307, states[0] = 28.774569, states[40]= 0.112895
Saving checkpoint... 
Iteration: 997789568, states[0] = -94.973130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009580542, states[0] = 0.482181, states[40]= 0.004345
Saving checkpoint... 
Iteration: 1021342803, states[0] = -95.009196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033043394, states[0] = 16.535904, states[40]= 0.005305
Saving checkpoint... 
Iteration: 1044831209, states[0] = -95.002865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056581307, states[0] = 0.052348, states[40]= 0.004288
Saving checkpoint... 
Iteration: 1068358835, states[0] = -95.016804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080055312, states[0] = 11.979611, states[40]= 0.005080
Saving checkpoint... 
Iteration: 1091830119, states[0] = -95.002206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103562522, states[0] = 9.046241, states[40]= 0.004988
Saving checkpoint... 
Iteration: 1115341939, states[0] = -95.008694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127101021, states[0] = -14.591538, states[40]= 0.001527
Saving checkpoint... 
Iteration: 1138806265, states[0] = -94.986493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150561331, states[0] = 9.543342, states[40]= 0.005006
Saving checkpoint... 
Iteration: 1162338313, states[0] = -95.006752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173977485, states[0] = -95.048035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185432475, states[0] = -95.040018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196515443, states[0] = 24.732820, states[40]= 0.017345
Saving checkpoint... 
Iteration: 1208002951, states[0] = 39.048146, states[40]= 0.131000
Saving checkpoint... 
Iteration: 1219727493, states[0] = -94.897367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231499180, states[0] = -95.050790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243256834, states[0] = -94.938956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254963383, states[0] = -95.045836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266734702, states[0] = -94.908666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278469062, states[0] = -95.046724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290220893, states[0] = -94.886312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301960302, states[0] = -95.045299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313710003, states[0] = -94.866851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325465471, states[0] = -95.046133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337207063, states[0] = -94.861334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348946766, states[0] = -95.042845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360693342, states[0] = -94.832738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371540033, states[0] = 17.757802, states[40]= 0.005443
Saving checkpoint... 
Iteration: 1383163862, states[0] = -85.314180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394889219, states[0] = -95.028216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406646439, states[0] = -59.760453, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1418395048, states[0] = -95.030068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430125643, states[0] = -37.123557, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1441858629, states[0] = -95.016496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453579406, states[0] = 1.106488, states[40]= 0.004423
Saving checkpoint... 
Iteration: 1465316525, states[0] = -94.993509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477050566, states[0] = 13.831326, states[40]= 0.005142
Saving checkpoint... 
Iteration: 1490003680, states[0] = 35.469176, states[40]= 0.144380
Saving checkpoint... 
Iteration: 1502911232, states[0] = -95.188737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515951980, states[0] = 9.439085, states[40]= 0.005715
Saving checkpoint... 
Iteration: 1529403342, states[0] = 38.033272, states[40]= 0.111302
Saving checkpoint... 
Iteration: 1542990443, states[0] = -20.754151, states[40]= 0.001014
Saving checkpoint... 
Iteration: 1556915637, states[0] = -95.243228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570775196, states[0] = -95.318575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584643402, states[0] = 13.084223, states[40]= 0.006117
Saving checkpoint... 
Iteration: 1598508857, states[0] = -40.967767, states[40]= 0.000127
Saving checkpoint... 
Iteration: 1612225828, states[0] = 20.890184, states[40]= 0.008306
Saving checkpoint... 
Iteration: 1626177375, states[0] = -95.178470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639955648, states[0] = -94.995229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653860685, states[0] = -95.313131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667688998, states[0] = -95.337255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681518991, states[0] = 23.338341, states[40]= 0.012417
Saving checkpoint... 
Iteration: 1695451653, states[0] = -94.673959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711202621, states[0] = 41.678075, states[40]= 0.098905
Saving checkpoint... 
Iteration: 1728969060, states[0] = -1.622392, states[40]= 0.004583
Saving checkpoint... 
Iteration: 1747021252, states[0] = -56.282597, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1765094993, states[0] = -95.218731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783217686, states[0] = 23.763336, states[40]= 0.014168
Saving checkpoint... 
Iteration: 1801314840, states[0] = -95.064204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819521473, states[0] = 23.066570, states[40]= 0.008779
Saving checkpoint... 
Iteration: 1838589948, states[0] = -6.446996, states[40]= 0.003121
Saving checkpoint... 
Iteration: 1857569505, states[0] = 5.693731, states[40]= 0.004844
Saving checkpoint... 
Iteration: 1876603106, states[0] = -16.879426, states[40]= 0.001253
Saving checkpoint... 
Iteration: 1895674905, states[0] = -94.275430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914735103, states[0] = -94.911460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933802896, states[0] = -94.984929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952832074, states[0] = -95.003629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971907528, states[0] = -95.033843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990861897, states[0] = -95.017821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009981899, states[0] = -95.048270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028279445, states[0] = -94.963232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047363562, states[0] = -95.018267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066399095, states[0] = -95.030903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085528119, states[0] = 21.693963, states[40]= 0.006667
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.926212
 - CaMKt in component CaMK (millimolar): 0.006993
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.579377
 - nass in component intracellular_ions (millimolar): 6.579437
 - ki in component intracellular_ions (millimolar): 145.399146
 - kss in component intracellular_ions (millimolar): 145.399126
 - cansr in component intracellular_ions (millimolar): 1.310420
 - cajsr in component intracellular_ions (millimolar): 1.271768
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880423
 - hs in component INa (dimensionless): 0.880418
 - j in component INa (dimensionless): 0.880390
 - hsp in component INa (dimensionless): 0.726626
 - jp in component INa (dimensionless): 0.880370
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709002
 - hLp in component INaL (dimensionless): 0.448132
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.614081
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.686854
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.925347
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999853
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.350346
 - xs1 in component IKs (dimensionless): 0.257708
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:28:45 (91049): called boinc_finish(0)

</stderr_txt>
]]>


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