𝕏

Task 54921249

Name HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_692_1
Workunit 26078883
Created 27 Jun 2024, 1:40:54 UTC
Sent 27 Jun 2024, 3:40:59 UTC
Report deadline 30 Jun 2024, 13:16:59 UTC
Received 27 Jun 2024, 12:29:14 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237767
Run time 1 hours 28 min 52 sec
CPU time 1 hours 27 min 38 sec
Validate state Valid
Credit 61.65
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.50 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.20.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_692.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_692_1_r724296785_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240627034041599520_ORdGradInc_k_24-Pueyo_APDR-conf_692_1_r724296785_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.054188
     * GNaL_b in INaL: 0.007198
     * Gto_b in Ito: 0.067666
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033382
     * GKs_b in IKs: 0.001779
     * GK1_b in IK1: 0.148266
     * Gncx_b in INaCa_i: 0.000956
     * Pnak_b in INaK: 62.766366
     * GKb_b in IKb: 0.004041
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043823
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11963554, states[0] = -94.929553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23474331, states[0] = -94.916211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35005402, states[0] = 30.420041, states[40]= 0.130775
Saving checkpoint... 
Iteration: 46979155, states[0] = -94.902865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58894495, states[0] = -94.881133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70830125, states[0] = -94.850903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82790085, states[0] = -94.820629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94811703, states[0] = -94.836080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106408016, states[0] = -94.878451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118385428, states[0] = -94.870912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130347884, states[0] = -94.855141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142283828, states[0] = -94.811341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154254490, states[0] = -94.779587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165830604, states[0] = -94.845236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177803194, states[0] = -94.826974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189738498, states[0] = -94.757603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201221955, states[0] = -94.731354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213127632, states[0] = -49.430436, states[40]= 0.000031
Saving checkpoint... 
Iteration: 225048937, states[0] = 11.958332, states[40]= 0.005315
Saving checkpoint... 
Iteration: 236948384, states[0] = -94.885285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248926890, states[0] = -94.880833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260552337, states[0] = 10.517703, states[40]= 0.005230
Saving checkpoint... 
Iteration: 272549185, states[0] = 11.855091, states[40]= 0.005308
Saving checkpoint... 
Iteration: 284534295, states[0] = 17.813305, states[40]= 0.006126
Saving checkpoint... 
Iteration: 296555030, states[0] = 9.352654, states[40]= 0.005170
Saving checkpoint... 
Iteration: 308580977, states[0] = -4.594368, states[40]= 0.003585
Saving checkpoint... 
Iteration: 320557979, states[0] = 8.047169, states[40]= 0.005103
Saving checkpoint... 
Iteration: 332574682, states[0] = -0.437066, states[40]= 0.004335
Saving checkpoint... 
Iteration: 344604358, states[0] = -25.838069, states[40]= 0.000672
Saving checkpoint... 
Iteration: 356213665, states[0] = -94.716448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368201359, states[0] = -94.692903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380114205, states[0] = -35.397496, states[40]= 0.000248
Saving checkpoint... 
Iteration: 392086158, states[0] = -8.689875, states[40]= 0.002687
Saving checkpoint... 
Iteration: 403929780, states[0] = -94.881356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415865118, states[0] = -94.861527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427424441, states[0] = -94.880128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439300325, states[0] = -94.824319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451251609, states[0] = -94.775184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463232503, states[0] = -94.748211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474773976, states[0] = -94.800773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486797445, states[0] = -94.822017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498743341, states[0] = -94.764115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510378070, states[0] = -94.866480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521977659, states[0] = -94.889802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533882695, states[0] = -94.868109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545442621, states[0] = -94.883956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556971695, states[0] = -94.888924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568914660, states[0] = -94.877657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580934369, states[0] = -94.882252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592963052, states[0] = -94.887568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604853117, states[0] = -94.856189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616412527, states[0] = -94.877079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627994086, states[0] = -94.891862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639960181, states[0] = -94.887072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651947043, states[0] = -94.884745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663498966, states[0] = -94.892408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675461813, states[0] = -94.887321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687392918, states[0] = -94.871406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699372352, states[0] = -94.864241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711349581, states[0] = -94.854468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723337000, states[0] = -94.848064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735313729, states[0] = -94.833917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747292429, states[0] = -94.817746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758896460, states[0] = -94.872463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770885761, states[0] = -94.869026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782501580, states[0] = 48.632643, states[40]= 0.063202
Saving checkpoint... 
Iteration: 793680473, states[0] = -94.638147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805685653, states[0] = -94.657989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817696720, states[0] = -94.683263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829301133, states[0] = -94.824727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841262213, states[0] = -94.787835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853220962, states[0] = -94.729125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864739195, states[0] = -94.758017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876702503, states[0] = -94.694886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888674489, states[0] = -94.571951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900565425, states[0] = 4.558777, states[40]= 0.004885
Saving checkpoint... 
Iteration: 912478325, states[0] = -94.889676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924052654, states[0] = 10.382283, states[40]= 0.005223
Saving checkpoint... 
Iteration: 936047231, states[0] = 12.671997, states[40]= 0.005364
Saving checkpoint... 
Iteration: 948073281, states[0] = 0.388389, states[40]= 0.004452
Saving checkpoint... 
Iteration: 959994637, states[0] = -94.891742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971971880, states[0] = -94.888719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983505643, states[0] = 30.003035, states[40]= 0.125956
Saving checkpoint... 
Iteration: 995003092, states[0] = 39.089594, states[40]= 0.127246
Saving checkpoint... 
Iteration: 1006563426, states[0] = 5.528686, states[40]= 0.004955
Saving checkpoint... 
Iteration: 1018567218, states[0] = 3.662480, states[40]= 0.004811
Saving checkpoint... 
Iteration: 1030168635, states[0] = -94.278560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042133760, states[0] = -56.318162, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1054112129, states[0] = -33.360592, states[40]= 0.000322
Saving checkpoint... 
Iteration: 1066096920, states[0] = -18.673140, states[40]= 0.001092
Saving checkpoint... 
Iteration: 1078062615, states[0] = 5.914367, states[40]= 0.004980
Saving checkpoint... 
Iteration: 1090068995, states[0] = 2.745585, states[40]= 0.004726
Saving checkpoint... 
Iteration: 1102067783, states[0] = 3.374251, states[40]= 0.004785
Saving checkpoint... 
Iteration: 1113656363, states[0] = -87.109176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125676644, states[0] = -94.606457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137284936, states[0] = -94.810960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148864173, states[0] = -94.860726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160452189, states[0] = -94.885405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172453381, states[0] = -94.885611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184459488, states[0] = -94.886653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196461176, states[0] = -94.886926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208420538, states[0] = -94.878764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219995704, states[0] = -94.891723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232037864, states[0] = 16.453075, states[40]= 0.005816
Saving checkpoint... 
Iteration: 1244002734, states[0] = 41.229336, states[40]= 0.116346
Saving checkpoint... 
Iteration: 1255564967, states[0] = 4.783644, states[40]= 0.004902
Saving checkpoint... 
Iteration: 1267574800, states[0] = -0.507636, states[40]= 0.004324
Saving checkpoint... 
Iteration: 1279156827, states[0] = -87.731371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290738610, states[0] = -94.756927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302639352, states[0] = -62.834146, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1314228730, states[0] = -94.741785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325370379, states[0] = -94.863127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337296180, states[0] = -94.820520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349156450, states[0] = -87.227547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361172957, states[0] = -94.532480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373176942, states[0] = -94.609826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385168357, states[0] = -94.249477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397040873, states[0] = 15.266739, states[40]= 0.005626
Saving checkpoint... 
Iteration: 1408593814, states[0] = -15.688804, states[40]= 0.001413
Saving checkpoint... 
Iteration: 1420541104, states[0] = 15.174391, states[40]= 0.005613
Saving checkpoint... 
Iteration: 1432548076, states[0] = 12.320098, states[40]= 0.005339
Saving checkpoint... 
Iteration: 1444573070, states[0] = 0.510203, states[40]= 0.004468
Saving checkpoint... 
Iteration: 1456608018, states[0] = -29.368137, states[40]= 0.000500
Saving checkpoint... 
Iteration: 1468211872, states[0] = -94.712518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479780372, states[0] = -94.806514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491728869, states[0] = -94.741908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503282127, states[0] = -95.129407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1514784204, states[0] = -19.778620, states[40]= 0.001075
Saving checkpoint... 
Iteration: 1526289246, states[0] = -95.033396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538218035, states[0] = -60.305707, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1550069213, states[0] = -95.166520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561583154, states[0] = -20.444792, states[40]= 0.001029
Saving checkpoint... 
Iteration: 1573185822, states[0] = -95.189349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585119646, states[0] = -95.119561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596617426, states[0] = 22.887785, states[40]= 0.015366
Saving checkpoint... 
Iteration: 1608599392, states[0] = -95.204682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620531044, states[0] = -95.140167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632477362, states[0] = -95.041832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644378002, states[0] = -15.266130, states[40]= 0.001648
Saving checkpoint... 
Iteration: 1656336496, states[0] = 14.465363, states[40]= 0.006778
Saving checkpoint... 
Iteration: 1668246216, states[0] = -95.160684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679764281, states[0] = -2.098044, states[40]= 0.004560
Saving checkpoint... 
Iteration: 1691685738, states[0] = -95.197795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703649968, states[0] = -95.165184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715576393, states[0] = -95.040726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727189409, states[0] = -27.900767, states[40]= 0.000568
Saving checkpoint... 
Iteration: 1738730638, states[0] = -95.141493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1750705060, states[0] = -95.101131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762738890, states[0] = -95.152271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1774281599, states[0] = -19.278602, states[40]= 0.001137
Saving checkpoint... 
Iteration: 1786254991, states[0] = 4.261069, states[40]= 0.005512
Saving checkpoint... 
Iteration: 1798173462, states[0] = -95.188104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810102737, states[0] = -27.416829, states[40]= 0.000610
Saving checkpoint... 
Iteration: 1821616244, states[0] = -39.872723, states[40]= 0.000135
Saving checkpoint... 
Iteration: 1833474392, states[0] = -94.919467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845049910, states[0] = 11.214835, states[40]= 0.005295
Saving checkpoint... 
Iteration: 1856945422, states[0] = -94.899579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1868486706, states[0] = -94.901627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880397747, states[0] = -94.880303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891922112, states[0] = -94.884565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1903935936, states[0] = -94.885956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915547315, states[0] = 12.593957, states[40]= 0.005362
Saving checkpoint... 
Iteration: 1927482255, states[0] = -94.891732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939429679, states[0] = -94.881948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951462718, states[0] = -94.887789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963409674, states[0] = -94.876293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975451375, states[0] = -94.885303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987591533, states[0] = -13.544836, states[40]= 0.001731
Saving checkpoint... 
Iteration: 1999709499, states[0] = -94.708009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2011711098, states[0] = -94.710922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022939589, states[0] = -94.882620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034923176, states[0] = -94.878984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046873272, states[0] = -94.863861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058778218, states[0] = -94.804114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070702457, states[0] = -94.694108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2082665381, states[0] = -93.758827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094197281, states[0] = -94.683663, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.767564
 - CaMKt in component CaMK (millimolar): 0.006780
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.820246
 - nass in component intracellular_ions (millimolar): 6.820305
 - ki in component intracellular_ions (millimolar): 145.159243
 - kss in component intracellular_ions (millimolar): 145.159224
 - cansr in component intracellular_ions (millimolar): 1.307158
 - cajsr in component intracellular_ions (millimolar): 1.269872
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003668
 - hf in component INa (dimensionless): 0.877651
 - hs in component INa (dimensionless): 0.877647
 - j in component INa (dimensionless): 0.877618
 - hsp in component INa (dimensionless): 0.721418
 - jp in component INa (dimensionless): 0.877599
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.707012
 - hLp in component INaL (dimensionless): 0.449879
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.623268
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.697859
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934759
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001596
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.341749
 - xs1 in component IKs (dimensionless): 0.238050
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997372
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:17:59 (231206): called boinc_finish(0)

</stderr_txt>
]]>


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